• drug
  • These include a slow onset of action, variable dose requirements reflecting, at least in part, common genetic polymorphisms that influence their metabolism, differences in dietary intake of vitamin K, and numerous drug-drug interactions that increase or decrease their anticoagulant effect. (ahajournals.org)
  • Significantly, this drug is used as an anticoagulant in humans. (alzforum.org)
  • treatment
  • People using anticoagulants to treat this condition should avoid using bed rest as a complementary treatment because there are clinical benefits to continuing to walk and remaining mobile while using anticoagulants in this way. (wikipedia.org)
  • effect
  • Their intake should be avoided whilst taking anticoagulants or, if coagulability is being monitored, their intake should be kept approximately constant so that anticoagulant dosage can be maintained at a level high enough to counteract this effect without fluctuations in coagulability. (wikipedia.org)