• epitopes
  • For established targets we seek to add antibodies that recognize new epitopes, including post-translational modifications such as phosphorylation and methylation. (abgent.com)
  • Cross-reactive antibodies to shared epitopes between B. burgdorferi and the endocarditis organism may account for the high false-positive results. (prohealth.com)
  • Bacteria
  • As a consequence, the bacteria are protected against phagocytic killing, whereas in blood plasma where the concentration of IgG is high, the antibodies preferentially bind via Fab, facilitating opsonization and bacterial killing. (lu.se)
  • Bacterial display (or bacteria display or bacterial surface display) is a protein engineering technique used for in vitro protein evolution. (wikipedia.org)
  • He enjoys international recognition as an authority on the basic biology and medical significance of atypical bacterial organisms and is considered a pioneer and an expert on the role of these unusual bacteria in the persistence and expression of kidney and urological infectious diseases. (wikipedia.org)
  • They noted that the forms, which they called electron dense bodies were so small that they could pass through bacterial filters that normally withheld ordinary bacteria with cell walls. (wikipedia.org)
  • After applying these data to the human condition, Domingue reasoned that in some patients who suffer from chronic bacterial infections, the disease process could be related to the fact that bacteria are able to differentiate into the resistant electron dense bodies that he observed in tissue cultures. (wikipedia.org)
  • The papers detail how L-form bacteria inside an experimental human embryonic kidney tissue culture system are able to persist in cells and explains how they are able to revert into the cell wall-containing parent bacterial form. (wikipedia.org)
  • Passive immunity is also provided through colostrum and breast milk, which contain IgA antibodies that are transferred to the gut of the infant, providing local protection against disease causing bacteria and viruses until the newborn can synthesize its own antibodies. (wikipedia.org)
  • ELISA
  • Demonstration of antibodies against the agent either with the classic Huddleson, Wright, and/or Bengal Rose reactions, either with ELISA or the 2-mercaptoethanol assay for IgM antibodies associated with chronic disease Histologic evidence of granulomatous hepatitis on hepatic biopsy Radiologic alterations in infected vertebrae: the Pedro Pons sign (preferential erosion of the anterosuperior corner of lumbar vertebrae) and marked osteophytosis are suspicious of brucellic spondylitis. (wikipedia.org)
  • Identification of specific antibodies against bacterial lipopolysaccharide and other antigens can be detected by the standard agglutination test (SAT), rose Bengal, 2-mercaptoethanol (2-ME), antihuman globulin (Coombs') and indirect enzymelinked immunosorbent assay (ELISA). (wikipedia.org)
  • gastric
  • By 2003 several PDP products for the treatment of human diseases were under development by nearly 200 biotech companies, including recombinant gastric lipase for the treatment of cystic fibrosis, and antibodies for the prevention of dental caries and the treatment of non-Hodgkin's lymphoma. (wikipedia.org)
  • affinity
  • The unique property of specific high-affinity binding to more or less any target of interest has made antibodies tremendously useful in numerous applications. (diva-portal.org)
  • targets
  • We provide tools for path-breaking research by developing antibodies that detect a comprehensive library of novel and established targets. (abgent.com)
  • For new targets we consult with leading experts to accelerate development of antibodies that will propel state-of-the-art research in cellular health and disease. (abgent.com)
  • high
  • High-resolution imaging was employed to explore the structural features of fimbriae as well as monitoring the antibody-fimbriae interactions. (diva-portal.org)
  • Type
  • Bacteriophage display is the most common type of display system used although bacterial display is becoming increasingly popular as technical challenges are overcome. (wikipedia.org)
  • Maternal passive immunity is a type of naturally acquired passive immunity, and refers to antibody-mediated immunity conveyed to a fetus or infant by its mother. (wikipedia.org)
  • clinical
  • The bacterial evolution, indeed, led to the emergence of antibiotic resistance as soon as the clinical consumption of antibiotics started. (diva-portal.org)
  • disease
  • Both seroprevalence and antibody optical density index exhibited 1-year cycles, indicating that disease outbreaks were seasonal and suggesting that long-lasting antibody protection was transient. (nih.gov)
  • Passive immunization can be provided when people cannot synthesize antibodies, and when they have been exposed to a disease that they do not have immunity against. (wikipedia.org)
  • Cell
  • Crown antibodies pass additional stringent quality requirements, including extended control sets, uniform results against multiple biologically relevant cell lines and tissues, and function in multiple applications. (abgent.com)
  • presence
  • The aims of this thesis are: to provide insight into the structural and biomechanical differences of fimbriae expressed by enterotoxigenic and uropathogenic Escherichia coli, and to investigate how fimbrial mechanics are affected in the presence of anti-fimbrial antibodies. (diva-portal.org)
  • We used force measuring optical tweezers to characterize the force-extension responses of fimbriae in the absence and presence of antibodies. (diva-portal.org)
  • either
  • It binds to an antibody at either κ or λ light chains using hydrogen bonds and salt bridges, from backbone atoms and conserved side chains, and some conserved van der Waals interactions with other nonconserved interactions. (wikipedia.org)
  • results
  • Proper validation with controls and optimization ensure the quality of the antibody, and establish confidence in your results. (abgent.com)
  • Further
  • Further investigation showed that efficient bacterial IgGFc-binding occurs only in IgG-poor environments, such as saliva. (lu.se)