• Garcinia
  • In a study in Zucker rats, which are genetically predisposed to obesity, Garcinia cambogia extract containing HCA showed that high doses led to significant suppression of epididymal fat accumulation, but also had high testicular toxicity. (wikipedia.org)
  • obese
  • The antiobesity effects of a P. aviculare ethanol extract (PAE) in high-fat diet- (HFD-) induced obese mice were investigated. (hindawi.com)
  • These results suggest that PAE exerts antiobesity effects in HFD-induced obese mice through the suppression of lipogenesis in adipose tissue and increased antioxidant activity. (hindawi.com)
  • receptor
  • The 5-HT2c receptor agonist Fenfluramine (market names Pondimin, Ponderax and Adifax) was discovered in 1972 as a result of research performed to identify anorectic compounds lacking the effects of psycho-stimulants and sympathomimetic agents (such as amphetamines). (wikipedia.org)
  • However it was still considered a successful proof of concept of the potential of Y5 receptor antagonists as possible anti-obesity agents in future. (wikipedia.org)
  • drug
  • The present invention comprises a transdermal drug delivery device comprising a reservoir comprising a releasably stored dosage of a pharmaceutically active agent and a translucent film adjacent to at least a portion of the reservoir, wherein the translucent film comprises at least one inorganic ultraviolet-absorbing. (google.ca)
  • 15 . A transdermal drug delivery device according to claim 1 , wherein the pharmaceutically active agent may undergo ultraviolet light induced degradation. (google.ca)
  • A closely related type of drug is a serotonin-dopamine releasing agent (SDRA). (wikipedia.org)
  • Lipase inhibitors belong to a drug class that is used as an antiobesity agent. (wikipedia.org)
  • Cetilistat, a new lipase inhibitor, is an experimental drug for obesity. (wikipedia.org)
  • doi: 10.1021/acs.oprd.5b00023 George M, Rajaram M, Shanmugam E. New and emerging drug molecules against obesity. (wikipedia.org)
  • Methods
  • One of the most recent methods that is being developed for the delivery of anti-angiogenesis factors to tumour regions in cancer sufferers is using genetically modified bacteria that are able to colonize solid tumors in vivo. (wikipedia.org)
  • loss
  • The compound was found to potently induce body-fat loss while preserving protein stores in animals which is the ultimate goal of an anti-obesity agent as body protein loss is an undesired but inevitable (to some degree) side effect of fat loss via calorie restriction. (wikipedia.org)
  • factors
  • This method involves genetically engineering bacterial species such as Clostridium, Bifidobacteria and Salmonella by adding the genes for anti-angiogenic factors such as endostatin or IP10 chemokine and removing any harmful virulence genes. (wikipedia.org)