Loading...
  • Disease
  • Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's disease, is a severe neurodegenerative syndrome that is associated with a particular mutation of the androgen receptor's polyglutamine tract called a trinucleotide repeat expansion. (wikipedia.org)
  • high androgen
  • The unwanted effects produced by high androgen output can be regulated through natural means that are obtainable and simple to incorporate into daily life. (reference.com)
  • In addition to PCOS, other causes of high androgen levels (called hyperandrogenism) include congenital adrenal hyperplasia (a genetic disorder affecting the adrenal glands that afflicts about one in 10,000 to one in 18,000 Americans, about half of whom are women) and other adrenal abnormalities, and ovarian or adrenal tumors. (healthywomen.org)
  • androstenedione
  • She also had low cortisol (and its precursors 17[alpha]-hydroxyprogesterone and 11-deoxycortisol), low adrenal androgens (DHEA sulfate and androstenedione), high mineralocorticoids precursors (11-deoxycorticosterone and corticosterone), high ACTH, and chromosomal analysis revealed a normal male karyotype 46 XY. (thefreedictionary.com)
  • testes
  • Androgens are synthesized in the testes , the ovaries , and the adrenal glands . (wikipedia.org)
  • during the embryonic stage of development, testes form in an androgen-independent process that occurs due to the influence of the SRY gene on the Y chromosome. (wikipedia.org)
  • MIH and androgens cooperate to allow for movement of testes into the scrotum. (wikipedia.org)
  • Immature sperm cells in the testes do not mature past an early stage, as sensitivity to androgens is required in order for spermatogenesis to complete. (wikipedia.org)
  • estrogen
  • In adult women, androgens are necessary for estrogen synthesis and have been shown to play a key role in the prevention of bone loss, as well as sexual desire and satisfaction. (healthywomen.org)
  • Androgens cause slow epiphysis, or maturation of the bones, but more of the potent epiphysis effect comes from the estrogen produced by aromatization of androgens. (wikipedia.org)
  • secondary
  • At the time of puberty, androgen levels increase dramatically in males, and androgens mediate the development of masculine secondary sexual characteristics as well as the activation of spermatogenesis and fertility and masculine behavioral changes such as gynephilia and increased sex drive. (wikipedia.org)
  • gonads
  • This process is triggered by androgens produced by the gonads, which in genetic females had earlier become ovaries, but in genetic males had become testicles due to the presence of the Y Chromosome. (wikipedia.org)
  • cyproterone acetate
  • Such conditions may be treated with drugs with antiandrogen actions, including androgen receptor antagonists such as cyproterone acetate, spironolactone, and bicalutamide, 5α-reductase inhibitors such as finasteride and dutasteride, CYP17A1 inhibitors such as abiraterone acetate, gonadotropin-releasing hormone (GnRH) analogues such as leuprolide and cetrorelix, and/or other antigonadotropins such as megestrol acetate and medroxyprogesterone acetate. (wikipedia.org)
  • males
  • The Free Androgen Index is not valid for adult males Robinson S, Rodin DA, Deacon A, Wheeler MJ, Clayton RN (March 1992). (wikipedia.org)
  • libido
  • Low androgen levels can be a problem as well, producing effects such as low libido (interest in or desire for sex), fatigue, decreased sense of well-being and increased susceptibility to bone loss, osteoporosis and fractures. (healthywomen.org)
  • Small studies find they are effective in boosting libido, energy and well-being in women with androgen deficiencies, as well as providing added protection against bone loss. (healthywomen.org)
  • PCOS
  • The results of this study show the benefits of marjoram tea in women with PCOS by reducing adrenal androgens and improving insulin sensitivity. (thefreedictionary.com)
  • Left untreated, high levels of androgens, regardless of whether a woman has PCOS or not, are associated with serious health consequences, such as insulin resistance and diabetes, high cholesterol, high blood pressure and heart disease. (healthywomen.org)
  • tract
  • This action of androgens is supported by a hormone from Sertoli cells, Müllerian inhibitory hormone (MIH), which prevents the embryonic Müllerian ducts from developing into fallopian tubes and other female reproductive tract tissues in male embryos. (wikipedia.org)
  • At the Center for Congenital Anomalies of the Reproductive Tract , we understand the needs of a girl with androgen insensitivity. (childrenshospital.org)
  • levels
  • Low androgen levels may affect women at any age, but most commonly occur during the transition to menopause, or "perimenopause," a term used to describe the time before menopause (usually two to eight years). (healthywomen.org)
  • Androgen levels begin dropping in a woman's 20s, and by the time she reaches menopause, have declined 50 percent or more from their peak as androgen production declines in the adrenal glands, and the mid-cycle ovarian androgen boost lessens or evaporates altogether. (healthywomen.org)
  • Surprising new research findings show that male lemurs' androgen levels increase the more they engage in child care behaviors. (wn.com)
  • Symptoms of androgen insensitivity experienced by men with SBMA are also progressive and include testicular atrophy, severe oligospermia or azoospermia, gynecomastia, and feminized skin changes despite elevated androgen levels. (wikipedia.org)