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  • high
  • The close proximity on chromosome 6 and high sequence homology to the other trace amine receptors suggest that TA4 is likely to bind a related or unidentified amine. (genetex.com)
  • compounds
  • Compounds with a nitrogen atom attached to a carbonyl group, thus having the structure R-CO-NR′R″, are called amides and have different chemical properties from amines. (wikipedia.org)
  • It is a broad class of compounds that encompasses anilines, but also many more complex aromatic rings and many amine substituents beyond NH2. (wikipedia.org)
  • Heterocyclic amines, also sometime referred to as HCAs, are chemical compounds containing at least one heterocyclic ring, which by definition has atoms of at least two different elements, as well as at least one amine (nitrogen-containing) group. (wikipedia.org)
  • Typically it is a nitrogen atom of an amine group that also makes the ring heterocyclic (e.g., pyridine), though compounds exist in which this is not the case (e.g., the drug Zileuton). (wikipedia.org)
  • The commercial products, which contain amine fluoride or compounds of this with tin-fluoride in their formula, are present under different forms: - gels, - fluids, - dentifrice, - mouth rinse. (wikipedia.org)
  • chiral
  • Amines of the type NHRR′ and NRR′R″ are chiral: the nitrogen center bears four substituents counting the lone pair. (wikipedia.org)
  • demonstrated that a ferrocene derivative bearing a chiral amine substituent could participate in directed ortho lithiation of the same ring of the ferrocene, yielding products with planar chirality diastereoselectively. (wikipedia.org)
  • alcohols
  • For example, methyl and ethyl amines are gases under standard conditions, whereas the corresponding methyl and ethyl alcohols are liquids. (wikipedia.org)
  • Thus the melting point and boiling point of amines is higher than those of the corresponding phosphines, but generally lower than those of the corresponding alcohols and carboxylic acids. (wikipedia.org)
  • metabolites
  • Modern psychopharmacology gave rise to the amine hypotheses of affective disorders and the search began for amine metabolites that could fulfil our hopes for biological markers of depression and mania. (springer.com)
  • In the Meisenheimer rearrangement (after Jakob Meisenheimer) certain N-oxides R1R2R3N+O− rearrange to hydroxylamines R2R3N−O−R1 in a 1,2-rearrangement: or a 2,3-rearrangment: In the Polonovski reaction a tertiary N-oxide is cleaved by acetic acid anhydride to the corresponding acetamide and aldehyde: Amine oxides are common metabolites of medication and psychoactive drugs. (wikipedia.org)
  • solubility
  • The lone electron pair is represented in this article by a two dots above or next to the N. The water solubility of simple amines is enhanced by hydrogen bonding involving these lone electron pairs. (wikipedia.org)
  • Small aliphatic amines display significant solubility in many solvents , whereas those with large substituents are lipophilic. (wikipedia.org)
  • fatty
  • In chemistry, a fatty amine is any amine attached to a hydrocarbon chain of eight or more carbon atoms in length. (wikipedia.org)
  • More commonly fatty amines are derived from C12-C18 hydrocarbons, which in turn are derived from the more abundant fatty acids. (wikipedia.org)
  • RCOOH + NH3 → RC≡N + 2 H2O The fatty amine is obtained from this by hydrogenation with any of a number of reagents, including Raney nickel or cobalt, and copper chromite catalysts. (wikipedia.org)
  • methyl
  • This is usually accomplished by quaternization of the amine with methyl iodide or acetic acid, which upon heating eliminates, resulting in a stable α-ferrocenylethyl cation intermediate. (wikipedia.org)
  • acetic
  • Amine oxides are readily converted to the parent amine by common reduction reagents including lithium aluminium hydride, sodium borohydride, catalytic reduction, zinc / acetic acid, and iron / acetic acid. (wikipedia.org)
  • reactivity
  • The presence of an amine group strongly increases the reactivity of the aromatic ring, due to an electron-donating effect. (wikipedia.org)
  • surfactants
  • Amine oxides are surfactants commonly used in consumer products such as shampoos, conditioners, detergents, and hard surface cleaners. (wikipedia.org)
  • Long-chain alkyl amine oxides are used as amphoteric surfactants and foam stabilizers. (wikipedia.org)
  • Eye irritation due to amine oxides and other surfactants is moderate and temporary with no lasting effects. (wikipedia.org)
  • group
  • Higher amines have the prefix amino as a functional group. (wikipedia.org)
  • So my thoughts, would the oxygens on the nitrite substitute off the hydrogens on the amine group? (thestudentroom.co.uk)
  • Amine oxides are used as protecting group for amines and as chemical intermediates. (wikipedia.org)
  • Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists - and hence, monoaminergic neuromodulators - that are structurally and metabolically related to classical monoamine neurotransmitters. (wikipedia.org)
  • atoms
  • Pyrimidine is a heterocyclic amine that contains two nitrogen atoms in an unsaturated six-membered ring. (wikipedia.org)
  • Surfaces
  • Achieve consistent and reproducible results in cell culture assays with Corning PureCoat amine and carboxyl surfaces-chemically defined, animal-free enhanced cell culture surfaces that are manufactured using a proprietary surface technology to deliver high lot-to-lot consistency. (corning.com)
  • Due to their surface activity the amine fluorides are rapidly dispersed in the oral cavity and wet all surfaces. (wikipedia.org)
  • Amine fluoride covers the tooth surfaces with a homogenous molecular layer. (wikipedia.org)
  • hydrogen
  • Aromatic amines, such as aniline , have their lone pair electrons conjugated into the benzene ring, thus their tendency to engage in hydrogen bonding is diminished. (wikipedia.org)
  • examples
  • Examples of cyclic amines include the 3-membered ring aziridine and the six-membered ring piperidine . (wikipedia.org)
  • Examples of noncatecholamine sympathomimetic amines include ephedrine, phenylephrine, methoxamine and salbutamol. (reference.com)
  • Dopamine
  • Dopamine is also a catecholamine sympathomimetic amine and its effects are similar to a lower dose of adrenaline. (reference.com)
  • Like dopamine, norepinephrine, and serotonin, the trace amines have been implicated in a vast array of human disorders of affect and cognition, such as ADHD, depression and schizophrenia, among others. (wikipedia.org)
  • footballer
  • Amine Khammas (born 6 April 1999) is a footballer who currently plays for Belgian club K.R.C. Genk. (wikipedia.org)
  • Amine Ferid Gouiri (born 16 February 2000) is a French professional footballer, who plays for Ligue 1 club Olympique Lyonnais as a striker. (wikipedia.org)
  • substitution
  • The reaction is called nucleophilic aliphatic substitution (of the halide), and the reaction product is a higher substituted amine. (wikipedia.org)
  • Moroccan
  • Amine Laâlou (born 13 May 1982) is a Moroccan track and field athlete, who specializes in middle-distance running. (wikipedia.org)
  • include
  • Important representatives include dimethylamine , while an example of an aromatic amine would be diphenylamine . (wikipedia.org)
  • procedure
  • The standard describes a procedure to detect EU banned aromatic amines derived from azo colorants in textile fibres, including natural, man-made, regenerated, and blended fibres. (wikipedia.org)
  • profile
  • 400 metres - 47.57 s (2005) 800 metres - 1:43.25 min (2006) 1500 metres - 3:29.53 min (2010) Amine Laâlou profile at IAAF Amine Laalou. (wikipedia.org)
  • significant
  • Trace amines play significant roles in regulating the quantity of monoamine neurotransmitters in the synaptic cleft of monoamine neurons with co-localized TAAR1. (wikipedia.org)
  • drugs
  • Sympathomimetic amines are drugs that stimulate the sympathetic nervous system and induce various responses. (reference.com)
  • Amine oxides of anti-cancer drugs have been developed as prodrugs that are metabolized in the oxygen deficient cancer tissue to the active drug. (wikipedia.org)
  • Amine fluorides are dental drugs. (wikipedia.org)
  • High
  • High quality Amine inspired T-Shirts, Posters, Mugs and more by independent artists and designers from around the world. (redbubble.com)
  • The high diastereoselectivity is independent of the electrophile used to trap the metalate, providing evidence for the stereoinductive step being lithiation and allowing broad synthetic utility of Ugi's amine. (wikipedia.org)
  • Research has shown that heterocyclic amine formation in meat occurs at high cooking temperatures. (wikipedia.org)
  • possible
  • changes in trace amines, in particular PE, have been identified as a possible factor for the onset of attention deficit/hyperactivity disorder (ADHD) [5, 27, 43, (wikipedia.org)
  • certain
  • Since August 2012, the new standard EN 14362-1:2012 Textiles - Methods for determination of certain aromatic amines derived from azo colorants - Part 1: Detection of the use of certain azo colorants accessible with and without extracting the fibres is effective. (wikipedia.org)
  • Neurotransmitter Monoamine neurotransmitters Trace amine-associated receptor (TAAR) TAAR1 Certain trace amines (e.g., phenethylamine) functionally inhibit the vesicular monoamine transporter VMAT2, while others do not (e.g., octopamine). (wikipedia.org)