• paralysis
  • The classical variety manifests as quadriplegia, lower cranial nerve paralysis, and mutism with preservation of vertical gaze and, most notably, intact consciousness indicated by abilities to communicate via eye movements. (hindawi.com)
  • severe
  • Curran and Lang ( 26 ) placed akinetic mutism at the extreme end of the hydrocephalus-parkinsonian spectrum identifying the pathogenetic mechanism in a combination of severe bradykinesia/akinesia plus compromise of the ascending reticular activating system, such as the monoaminergic projection fibers from the brainstem in regions adjacent to the third ventricle that may be impaired when rapid ventricle dilatation occurs. (ispn.guide)