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  • stroke
  • Framingham Stroke Risk Score (FSRS) is the most well-regarded risk appraisal tools for evaluating an individual's absolute risk on stroke onset. (biomedcentral.com)
  • Modified C-statistics, Hosmer-Lemeshow Test and classless NRI, class NRI were the statistical indices which, respectively, denoted the performance of discrimination, calibration and reclassification for evaluating the newly developed risk prediction model on stroke onset. (biomedcentral.com)
  • n = 13,060) were observed through age 50 years for the development of ischemic heart disease and stroke. (readbyqxmd.com)
  • It is rare, often relatively unknown among laypersons and physicians and the wide variety of age-specific differential diagnoses (stroke mimics) as well as less established care structures often lead to a considerable delay in the diagnosis of stroke. (readbyqxmd.com)
  • subjects
  • Three-dimensional cortical gray matter density (GMD) maps were generated for 36 patients with recent-onset psychosis and 36 sex- and age-matched control subjects using a cortical pattern matching method. (pubmedcentralcanada.ca)
  • puberty
  • at 14, he entered the age of puberty, and was said to have acquired full puberty at 18 years accomplished, and was major on completing his 25th year. (thefreedictionary.com)
  • LOS ANGELES - A team of researchers led by Vicente Gilsanz, MD, PhD, director of Clinical Imaging at The Saban Research Institute of Children's Hospital Los Angeles, determined that the onset of puberty was the primary influence on adult bone mineral density, or bone strength. (healthcanal.com)
  • Given that the rate of decline of bone mass in adulthood is approximately 1% to 2% each year, a 10% to 20% increase in bone density resulting from a natural early puberty corresponds to an additional 10 to 20 years of protection against the normal age-related decline in bone strength. (healthcanal.com)
  • In many countries throughout the world, the age at which puberty occurs among girls-manifested as breast development, appearance of pubic hair, and onset of menarche-has been commencing earlier. (thesoyfoodscouncil.com)
  • These trends in pubertal development raise concerns because early onset of puberty may negatively influence the future health of adolescent girls. (thesoyfoodscouncil.com)
  • HNPCC
  • Revealing such associations in MMR mutation carriers may improve risk estimates and help to identify individuals who are genetically susceptible to developing HNPCC at an earlier age. (aacrjournals.org)
  • Combining knowledge of an individual's DNMT3b genotype with information on other genetic and environmental risk factors may improve risk estimates and help to identify individuals who are genetically susceptible to developing HNPCC at an earlier age. (aacrjournals.org)
  • symptoms
  • The age of onset is a medical term referring to the age at which an individual acquires, develops, or first experiences a condition or symptoms of a disease or disorder. (wikipedia.org)
  • By applying a new technique that combines independent lines of genomic evidence, Duke University Medical Center researchers and colleagues have identified a single gene that influences the age at which individuals first show symptoms of Alzheimer s and Parkinson s diseases. (innovations-report.com)
  • However, the age at which genetically-predisposed individuals develop symptoms of the disease is just as important, says Margaret Pericak-Vance, Ph.D., director of the Center for Human Genetics at Duke and principal investigator of the study. (eurekalert.org)
  • Each child has the symptoms above at different ages, yet most symptoms are eventually present. (wikipedia.org)
  • Symptoms of HSP may begin at any age, from infancy to older than 60 years. (wikipedia.org)
  • most signs of NF-1 are visible after birth (during infancy), but many symptoms of NF-1 occur as the person ages and has hormonal changes. (wikipedia.org)
  • In absence of retinal tears, the usual progress is that the vitreous humor will continue to age and liquefy and floaters will usually become less and less noticeable, and eventually most symptoms will completely disappear. (wikipedia.org)
  • gene
  • This study emphasizes the similarity between the two diseases by highlighting a single gene that influences their age of onset. (innovations-report.com)
  • Understanding the role this gene plays in Alzheimer and Parkinson diseases may, in the future, lead to a means to delay the disorders onset," she added, noting that even a short delay would benefit at-risk patients. (innovations-report.com)
  • We examined association between three PPARα gene polymorphisms (an A→C variant in intron 1, the L162V variant, and the intron 7 G→C variant) and age at diagnosis of type 2 diabetes in 912 Caucasian type 2 diabetic subjects. (diabetesjournals.org)
  • These data indicate that PPARα gene variation influences the onset and progression of type 2 diabetes. (diabetesjournals.org)
  • We therefore examined association between variation in the PPARα gene and age at diagnosis (as a surrogate for age of onset) and progression to type 2 diabetes in Caucasian type 2 diabetic participants in the University College Diabetes and Cardiovascular Study (UDACS) ( 16 ) and Ealing Diabetic Study of Coagulation (EDSC). (diabetesjournals.org)
  • findings
  • The findings showed that among all drinkers, early drinking was associated not only with a higher risk of developing alcoholism at some point, but also within 10 years of first starting to drink, before age 25, and within any year of adult life. (aim-digest.com)
  • progression
  • Metabolomics analysis of samples from children in the Finnish Type 1 Diabetes Prediction and Prevention (DIPP) study diagnosed with type 1 diabetes at 0.5-13.5 years of age ( 14 ) showed that serum metabolites may mark progression to islet autoimmunity and from islet autoimmunity to diabetes. (diabetesjournals.org)
  • Diabetes
  • The mean age of onset of type 1 diabetes was 26 in our study. (thefreedictionary.com)
  • It is hypothesized that the risk for type 1 diabetes at an early age may be increased by a pathogenic pregnancy and be reflected in altered cord-blood composition. (diabetesjournals.org)
  • This study used metabolomics to test if the cord-blood lipidome was affected in children diagnosed with type 1 diabetes before 8 years of age. (diabetesjournals.org)
  • The present case-control study of 76 index children diagnosed with type 1 diabetes before 8 years of age and 76 healthy control subjects matched for HLA risk, sex, and date of birth, as well as the mother's age and gestational age, revealed that cord-blood phosphatidylcholines and phosphatidylethanolamines were significantly decreased in children diagnosed with type 1 diabetes before 4 years of age. (diabetesjournals.org)
  • Factors triggering the onset of islet autoimmunity and the subsequent transition to overt diabetes are largely unknown, thus making a prevention strategy still a challenge. (diabetesjournals.org)
  • We compared 76 DiPiS children who developed type 1 diabetes before 8 years of age with 76 control subjects matched for HLA, sex, date of birth, and the mother's age. (diabetesjournals.org)
  • Diabetes Measure Kit Ii Age Onset Type research has shown that controlling ACE Inhibitor Treatment in Jasper's Page has more information on this treatment. (bestcities.eu)
  • Low magnesium levels not only make controlling blood sugar more difficult but also increase risk Always record your test Diabetes Measure Kit Ii Age Onset Type results in your logbook. (bestcities.eu)
  • Peroxisome proliferator-activated receptor (PPAR)α is a master regulator of fatty acid catabolism, and PPARα activators delay the onset of type 2 diabetes. (diabetesjournals.org)
  • Recently, bezafibrate was shown to reduce the incidence and delay the onset of type 2 diabetes, indicating that such effects may also occur in humans ( 11 ). (diabetesjournals.org)
  • diagnosis
  • Reduced levels of triglycerides correlated to gestational age in index and control children and to age at diagnosis only in the index children. (diabetesjournals.org)
  • Previous research has established the link between early onset of drinking and lifetime diagnosis of alcoholism. (aim-digest.com)
  • Even controlling for a number of risk factors and the effects of age differences among respondents, early drinking was associated with an increased risk of lifetime alcohol diagnosis. (aim-digest.com)
  • Atopic dermatitis was defined by a doctor's diagnosis reported by the parents of children up to 4 years of age, by questionnaires, and/or by positive SCORAD scores from 1 year of age and according to the age of onset within or after the first year of life. (biomedsearch.com)
  • The following is a list of conditions and complications associated with NF-1, and, where available, age range of onset and progressive development, occurrence percentage of NF-1 population, method of earliest diagnosis, and treatments and related medical specialties. (wikipedia.org)
  • patients
  • Of patients with ocular JXG, 92% are younger than the age of two. (wikipedia.org)
  • Several studies have found a broad range of incidence of PVD, from 20% of autopsy cases to 57% in a more elderly population of patients (average age was 83.4 years). (wikipedia.org)
  • disorders
  • The age of onset of mental health disorders have been found to be harder to define than physical illnesses. (wikipedia.org)
  • Similarly the earliest mean age of onset of the anxiety disorders is in preschool, for specific phobia. (thefreedictionary.com)
  • The major funding for the study was provided by the National Institute on Aging, the National Institute of Neurological Disorders and Stroke, the Alzheimer s Association, the Institute de France, and the American Federation for Aging Research. (innovations-report.com)
  • adolescents
  • We have used data from adolescents (n=5,392) ages 10-18 who participated in the 2003 Tobacco Survey, a representative sample of adolescents in Northwest Ohio. (mdpi.com)
  • Khuder SA, Price JH, Jordan T, Khuder SS, Silvestri K. Cigarette Smoking among Adolescents in Northwest Ohio: Correlates of Prevalence and Age at Onset. (mdpi.com)
  • significantly
  • Having a close friend that smoked and a smoker at home correlated significantly with both initiation of smoking and smoking at an earlier age. (mdpi.com)
  • Students who reported smoking by parents or siblings were significantly more likely to start smoking at an earlier age, compared to other students living in a non-smoking home environment. (mdpi.com)
  • Adverse childhood experience scores, a measure of exposure to adverse events in childhood, significantly predicted age of MS onset ( r = -0.30, p = 0.04). (frontiersin.org)
  • younger
  • Data from a survey of 43,000 U.S. adults published in the July issue of Archives of Pediatrics & Adolescent Medicine.suggests those who began drinking in their early teens are at greater risk of developing alcohol dependence at some point in their lives, of developing dependence more quickly and at younger ages, and of developing chronic, relapsing dependence. (aim-digest.com)
  • While one quarter of all drinkers in the survey started drinking by age 16, 46% of drinkers who developed alcohol dependence began drinking at age 16 or younger. (aim-digest.com)
  • individuals
  • Of the individuals who began drinking before age 14, 47% experienced dependence at some point, vs. 9% of those who began drinking at age 21 or older. (aim-digest.com)
  • Risk
  • citation needed] People with myopia (nearsightedness) greater than 6 diopters are at higher risk of PVD at all ages. (wikipedia.org)
  • cases
  • JXG usually manifests with multiple lesions on the head and neck in cases with children under six months of age. (wikipedia.org)
  • The most common symptom, in over 95% of cases, is a sudden-onset headache located behind the eyes or around the temples. (wikipedia.org)
  • among
  • 5. By the laws of France many provisions are made in respect to age, among which are the following. (thefreedictionary.com)
  • Among all respondents who developed alcoholism at some point, 47% met the diagnostic criteria for alcohol dependence (alcoholism) by age 21. (aim-digest.com)
  • delay
  • Understanding the regulation of onset will open new avenues of research that could one day make it possible to delay onset beyond an individual's normal lifespan," Pericak-Vance said. (eurekalert.org)
  • people
  • He is the co-author of a manual, Guidelines for social and economic rehabilitation of the rural blind, which prescribes guidelines for the rehabilitiaon of visually impaired people and a recipient of the All India Confederation of the Blind Award in 1987 and the International Award for Community Services Overseas of the Help the Aged, UK in 1991. (wikipedia.org)
  • PVD is rare in emmetropic people under the age of 40 years, and increases with age to 86% in the 90s. (wikipedia.org)
  • older
  • Scientists at the Boston University School of Public Health and Youth Alcohol Prevention Center, led by Dr. Ralph Hingson, carried out the analysis using data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a representative survey of the 43,000 U.S. civilians aged 18 years and older. (aim-digest.com)
  • develop
  • Current research is being performed to develop treatment methods for the aforementioned laminopathies and to investigate the role lamins play in the aging process. (wikipedia.org)
  • A British physician, Muir noted a patient with many keratoacanthomas who went on to develop several internal malignancies at a young age. (wikipedia.org)
  • over 75% of those over the age of 65 develop it. (wikipedia.org)