• Further studies indicate that adenoviruses are associated with 4 - 15% of all hospitalized cases of viral gastroenteritis. (rapidtest.com)
  • Adenoviruses have an incubation period of 8 - 10 days, followed by viral shedding for an approximate period of 7 - 14 days. (rapidtest.com)
  • Of interest is the role of adenoviruses as viral vectors in vaccination and in gene therapy.For example, in viral vector vaccines against SARS-CoV2, the vector virus is used to deliver RNA encoding SARS-CoV2 spike protein into target cells. (medscape.com)
  • Viral DNA and a viral peptide are cofactors of adenovirus virion proteinase activity. (microbiologyresearch.org)
  • Adenoviral DNA is retained by peripheral epithelial cells of the lung (PLECs) in humans in whom the viral E1A gene is expressed 4 without replication of a complete virus 5 . (ersjournals.com)
  • Human adenovirus has been described as a " viral pathogen with increasing importance ,' and outbreaks, though still relatively rare, typically occur in "congregate settings. (contagionlive.com)
  • Human Adenovirus Infection Causes Cellular E3 Ubiquitin Ligase MKRN1 Degradation Involving the Viral Core Protein pVII. (scilifelab.se)
  • Human adenoviruses (HAdVs) are common human pathogens encoding a highly abundant histone-like core protein, VII, which is involved in nuclear delivery and protection of viral DNA as well as in sequestering immune danger signals in infected cells. (scilifelab.se)
  • The most common viral pathogens recovered from hospitalized patients admitted with CAP include human rhinovirus and influenza . (medscape.com)
  • Human adenoviruses (HAdVs) are prevalent in patients with respiratory infections, in which recombination has important implications for viral detection and pathogenicity. (biomedcentral.com)
  • Intro Adenovirus vectors are believed a respected viral vector system for vaccines for their powerful immunogenicity and making feasibility. (synanet2020.com)
  • A comparison of 52 matched samples showed an excellent correlation between the quantitative viral loads measured by the in-house assay and the RealStar® Adenovirus PCR Kit (R 2 = 0.984), with an average bias of − 0.16 log 10 copies/mL. (biomedcentral.com)
  • As in the case of other viral respiratory pathogens, community outbreaks of adenovirus infections may occur, especially with respiratory tract infections and keratoconjunctivitis. (biomedcentral.com)
  • Adenovirus DNA : the viral genome and its expression / edited by Walter Doerfler. (who.int)
  • Serotypes (named with Arabic numbers) have been grouped into species designated Human adenovirus A-F. (childrensmercy.org)
  • Possessing over60 serotypes, adenovirus is recognized as the etiologic agent of various diverse syndromes. (medscape.com)
  • The Adenoviridae family consists of five genera, of which the genus Mastadenovirus includes human viruses classified into 57 serotypes clustered into 7 subgroups (A-G). Human adenoviruses have different organ tropisms, causing a wide variety of clinical manifestations including respiratory tract infections, acute conjunctivitis, cystitis, gastroenteritis and systemic infections in immunocompromised patients. (pjmonline.org)
  • The present study aimed to investigate the prevalence of adenovirus and RSV serotypes A and B in individuals with acute exacerbations of COPD (COPD‑AE) and stable COPD. (spandidos-publications.com)
  • Human Advs are divided into seven subgroups including 53 serotypes based on immunologic and biological characteristics. (hindawi.com)
  • The coxsackievirus-adenovirus receptor (CAR) appears to play a major role during infection of most human serotypes, whereas the alpha (v)beta (3/5) integrins have been reported to play a significant auxiliary role. (cnrs.fr)
  • Currently, human adenoviruses (HAdVs) are classified into seven groups (HAdV-A to HAdV-G), including 52 serotypes and 90 genotypes [ 4 ]. (biomedcentral.com)
  • They support the development of E1/E4-removed vectors predicated on Advertisement5 aswell as choice adenovirus serotypes (43C46). (synanet2020.com)
  • There are 7 human adenovirus species (A to G) and 57 serotypes. (msdmanuals.com)
  • Human adenoviruses (HAdVs) are members of the Adenoviridae family, group of medium-sized viruses characterized by a nonenveloped icosahedral nucleocapsid and a double stranded DNA genome. (pjmonline.org)
  • IMPORTANCE Human adenoviruses (HAdVs) are common pathogens causing a wide range of diseases. (scilifelab.se)
  • Human adenoviruses (HAdVs) can cause a variety of human illnesses, with associated temporal and geographic changes in disease incidence. (annals.edu.sg)
  • Human adenoviruses (HAdVs) are well known pathogens that cause a variety of human illnesses. (annals.edu.sg)
  • The first is lytic infection, which occurs when an adenovirus enters human epithelial cells and continues through an entire replication cycle, which results in cytolysis, cytokine production, and induction of host inflammatory response. (medscape.com)
  • The present study analyzed the effect of adenovirus on bacterial adherence to human respiratory tract epithelial cells. (lu.se)
  • Although miRNAs have been examined in Adv type 3-infected human laryngeal epithelial cells and Adv type 2-infected human lung fibroblast cells [ 19 , 20 ], there is no research about small RNA profiling in whole blood of Adv-infected pneumonia children. (hindawi.com)
  • Guinea pig primary peripheral lung epithelial cells (PLECs) transfected with adenovirus E1A (E1A-PLECs) were compared to guinea pig normal lung fibroblasts (NLFs) transfected with E1A (E1A-NLFs). (ersjournals.com)
  • Case-control studies have shown that the E1A DNA from group C adenoviruses is present in greater amounts in the lungs of patients with COPD than in controls with normal lung function matched for age, sex and smoking history 5 , and that the excess inflammation in the lungs of smokers with severe emphysema is associated with increased numbers of alveolar epithelial cells expressing E1A 6 . (ersjournals.com)
  • Human adenovirus 41 belongs to the Adenoviridae family, and along with human adenovirus 40, is a member of species human mastadenovirus F. It can particularly target the gastrointestinal tract to cause gastroenteritis in very young children. (wikipedia.org)
  • Quantitative real-time PCR assays for identification of species C human adenoviruses. (cdc.gov)
  • Species of the genus MASTADENOVIRUS, causing a wide range of diseases in humans. (childrensmercy.org)
  • Human adenovirus (HAdV) diversity in sewage was assessed by species-specific molecular methods. (pjmonline.org)
  • Adenoviruses from B species were not detected. (pjmonline.org)
  • The aim of this study was species-specific identification of human adenoviruses in sewage from Poland. (pjmonline.org)
  • Predominant adenovirus species in sewage were determined. (pjmonline.org)
  • Homologous recombination in E3 genes of human adenovirus species D. (bvsalud.org)
  • A comprehensive genomics and bioinformatics analysis of the E3 transcription unit for 38 viruses within human adenovirus species D (HAdV-D) revealed distinct and surprising patterns of homologous recombination . (bvsalud.org)
  • As of August 2022, human adenovirus 41 has been identified in a majority of small children with hepatitis of unknown cause in 2 case series. (wikipedia.org)
  • In an investigation of 5 children with an inflammation of the liver (hepatitis) of unknown cause at Birmingham, Alabama in October 2021, all turned out to have human adenovirus 41. (wikipedia.org)
  • In August 2022, 9 children in a U.S. case series of hepatitis of unknown cause and 27 of 30 children in a U.K. case series with hepatitis of unknown cause who underwent molecular testing tested positive for human adenovirus type 41 in a sample. (wikipedia.org)
  • CDC is investigating a possible association between pediatric hepatitis and adenovirus infection. (cdc.gov)
  • In seawater, the enteric adenoviruses have been shown to be substantially more stable than either polio 1 or hepatitis A virus (Enriquez and Gerba, 1995). (pjmonline.org)
  • Human Adenoviruses: From Villains To Vectors. (wikipedia.org)
  • Canine adenovirus type 2 (CAV-2) vectors may be attractive tools for gene transfer thanks to the lack of preexisting immunity in humans, and because of the preferential transduction of neurons when the vector is injected into the brain and some innervated tissues. (cnrs.fr)
  • Ex vivo infection of human corneas with adenoviral vectors containing lacZ, under transcriptional control of either cytomegalovirus (CMV) or Rous sarcoma virus (RSV) promoters, provided high-level gene expression, which was largely restricted to endothelium. (ox.ac.uk)
  • Following infection of human corneas with adenoviral vectors encoding CTLA-4 Ig protein, high levels of the fusion protein were detected in corneal culture supernatants for up to 28 days. (ox.ac.uk)
  • The strongest adenovirus vectors for make use of as vaccines derive from adenovirus serotype 5 (Advertisement5) (1C6). (synanet2020.com)
  • Adenovirus-based vectors can handle generating powerful and protecting T cell and antibody reactions in animal versions (7C17), and medical data conclusively display that Advertisement5 vectors can induce powerful Compact disc8+ and Compact disc4+ T cell and antibody reactions in vaccinated volunteers (18C25). (synanet2020.com)
  • The Advertisement5-centered hexon-modified vectors which contain subgroup D hypervariable areas (Advertisement43 or Advertisement48) induced powerful transgene-specific immune reactions which were unaffected by Advertisement5-particular NAb in murine and SLC2A3 non-human primate vaccine versions. (synanet2020.com)
  • In immunocompetent hosts, most adenovirus infections are asymptomatic. (msdmanuals.com)
  • abstract = "Human serum butyrylcholinesterase (Hu BChE) is a promising therapeutic against the toxicity of chemical warfare nerve agents, pesticide intoxication, and cocaine overdose. (nebraska.edu)
  • The role of adenovirus structural proteins in the regulation of adenovirus infection. (microbiologyresearch.org)
  • The present report concerns the role of adenovirus infection in inducing this transformation in an animal model of chronic obstructive pulmonary disease. (ersjournals.com)
  • four (8%) did not test positive for adenovirus. (cdc.gov)
  • The results showed that three sputum samples were positive for adenovirus in patients experiencing an exacerbation, while one was positive among the patients in a stable condition. (spandidos-publications.com)
  • Adenovirus has been associated with both sporadic and epidemic disease and, with regard to infections among military recruits, who were routinely immunized against types 4 and 7 from 1971 until the cessation of vaccine production in 1996. (medscape.com)
  • A live oral vaccine against adenovirus types 4 and 7 was approved for use in this population by the US Food and Drug Administration (FDA) in 2011, and subsequent incidence of acute respiratory disease declined. (medscape.com)
  • Adenovirus type 4 and type 7 live vaccine is used to prevent febrile (with fever) acute respiratory disease (ARD) caused by adenovirus type 4 and type 7. (drugs.com)
  • Appropriate studies have not been performed on the relationship of age to the effects of adenovirus type 4 and type 7 live vaccine in children up through 16 years of age. (drugs.com)
  • Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector. (emmes.com)
  • The development of an effective human immunodeficiency virus (HIV) vaccine is a high global priority. (emmes.com)
  • Here, we report the safety, tolerability, and immunogenicity of a replication-defective recombinant adenovirus serotype 5 (rAd5) vector HIV-1 candidate vaccine. (emmes.com)
  • Adenovirus serotype 14 (Ad14) is a rarely reported but emerging serotype of adenovirus that can cause severe and sometimes fatal respiratory illness in patients of all ages, including healthy young adults. (cdc.gov)
  • It is a double antibody (sandwich) ELISA using a polyclonal anti-adenovirus antibody to capture the antigen from the stool supernatant. (rapidtest.com)
  • The second incubation adds an additional anti-adenovirus antibody that sandwiches the antigen. (rapidtest.com)
  • Adenovirus is often cultured from the pharynx and stool of asymptomatic children, and most adults have measurable titers of anti-adenovirus antibodies, implying prior infection. (medscape.com)
  • Research has shown that enteric adenoviruses, primarily Ad40 and Ad41, are a leading cause of diarrhea in many of these children, second only to the rotaviruses. (rapidtest.com)
  • The diarrhea resulting from enteric adenoviruses is longer in duration than that caused by the rotaviruses, usually lasting 7 - 8 days. (rapidtest.com)
  • Enteric adenoviruses multiply in the gastrointestinal tract, and are excreted in large numbers in the faeces of infected persons (even more than 10 8 copies/g of stool). (pjmonline.org)
  • Exploring the potential of biotherapy through oncolytic adenoviruses is a hot area in cancer research. (sciencedaily.com)
  • A community outbreak of adenovirus was reported in Taiwan in 2011, using a vigilant surveillance system comprising 12 contract virological laboratories across the country. (annals.edu.sg)
  • These primary cell cultures were often noted to spontaneously degenerate over time, and adenoviruses are now known to be a common cause of asymptomatic respiratory tract infection that produces in vitro cytolysis in these tissues. (medscape.com)
  • Postmortem tracheal and gastric swabs from the infant were sent to the Wadsworth Center laboratory of the New York State Department of Health, where adenovirus was detected by polymerase chain reaction (PCR). (cdc.gov)
  • Adenoplex® multiplex polymerase chain reaction (PCR) kits and Invitek RTP® DNA/RNA Virus Mini kits were used for PCR assays of adenovirus and RSV, respectively. (spandidos-publications.com)
  • We evaluated the presence of influenza A/B virus, human metapneumovirus, bocavirus, adenovirus, respiratory syncytial virus (RSV), and parainfluenza viruses in 105 SARS-CoV-2 positive dead patients, using polymerase chain reaction (PCR) and reverse transcription PCR tests. (nih.gov)
  • The analytical sensitivity, specificity, linearity, precision and accuracy of an in-house adenovirus quantitative polymerase chain reaction assay were evaluated against the RealStar® Adenovirus PCR Kit (Altona Diagnostics GmbH, Hamburg, Germany), using 122 clinical specimens and 18 proficiency testing samples. (biomedcentral.com)
  • Human adenovirus 41 (HAdV-F41), is an enteric Adenovirus, a nonenveloped virus with an icosahedral nucleocapsid containing a double-stranded DNA genome. (wikipedia.org)
  • The genome of adenovirus is well known and can be modified with relative ease to induce lysis or cytotoxicity of a specified cell line without affecting others. (medscape.com)
  • Notably, the 12 cases reported between December 2016 and February 2017 in New Jersey involved the human adenovirus genome type 7d. (contagionlive.com)
  • We found coinfection with influenza virus in 22.3%, RSV, and bocavirus in 9.7%, parainfluenza viruses in 3.9%, human metapneumovirus in 2.9%, and finally adenovirus in 1.9% of SARS-CoV-2 positive dead cases. (nih.gov)
  • Our findings highlight a high prevalence of coinfection with influenza A virus and the monopoly of coinfection with Human metapneumovirus in children. (nih.gov)
  • The following presentation contains content made by external presenters and not by the Centers for Disease Control and Prevention or the Department of Health and Human Services. (cdc.gov)
  • Molecular typing of human adenovirus by PCR and sequence of a partial region of the hexon gene. (cdc.gov)
  • The gene for the adenovirus 2 hexon polypeptide. (microbiologyresearch.org)
  • Adenovirus protein- protein interactions: hexon and protein VI. (microbiologyresearch.org)
  • The CDC investigators tested respiratory specimens using generic pan-human adenovirus rPCR (pan-rPCR) assay to confirm detection and then typed the specimens using PCR and sequencing of hexon capsid protein gene hypervariable regions 1-6. (contagionlive.com)
  • Adenoviruses are DNA viruses classified according to 3 major capsid antigens (hexon, penton, and fiber). (msdmanuals.com)
  • Transverse chest CT images demonstrated in- We identified a case of fatal acute respiratory disease creased areas of patchy shadows and consolidation in both from household transmission of human adenovirus type lungs compared to CT images from April 22, indicative of 55 (HAdV-55) in Anhui Province, China. (cdc.gov)
  • Surprisingly, the endogenous MKRN1 protein underwent proteasomal degradation during the late phase of HAdV-C5 infection in various human cell lines. (scilifelab.se)
  • This information would enhance the understanding of recombination of HAdV-C, and might assist with effective prevention and control of respiratory adenovirus infection in Qinghai Province. (biomedcentral.com)
  • The HAdV positive samples were inoculated onto human laryngeal epidermoid cancer cells (HEp-2) cultured with DMEM containing 2% FBS for virus isolation. (biomedcentral.com)
  • The types of specimens you should collect for human adenovirus detection depend on the patient's clinical presentation and type of infection. (cdc.gov)
  • To improve human adenovirus detection, you should collect specimens within a week of symptom onset. (cdc.gov)
  • Quantitative real-time PCR assay panel for detection and type-specific identification of the epidemic respiratory human adenoviruses. (cdc.gov)
  • However, increased awareness of human adenoviruses and availability of molecular testing methods has allowed for increased detection and identification of human adenoviruses. (contagionlive.com)
  • The in-house adenovirus assay is a sensitive and reliable assay with lower cost for the detection and quantification of adenoviral DNA when compared to the RealStar® Adenovirus PCR Kit. (biomedcentral.com)
  • Human adenovirus (Adv) infection is responsible for most community-acquired pneumonia in infants and children, which results in significant morbidity and mortality in children every year. (hindawi.com)
  • Knowing the miRNA expression profile will help understand the role of miRNAs in modulating the host response to adenovirus infection and possibly improve the diagnosis of adenovirus-infected pneumonia. (hindawi.com)
  • In our study, total RNA extracted from whole blood of adenovirus-infected pneumonia children and healthy controls were analyzed by small RNA deep sequencing. (hindawi.com)
  • These highly upregulated microRNAs may have crucial roles in Adv pathogenesis and are potential biomarkers for adenovirus-infected pneumonia. (hindawi.com)
  • Human adenovirus (Adv) infection is responsible for most community-acquired pneumonia in infants and children [ 1 , 2 ]. (hindawi.com)
  • Viruses are microscopic organisms that survive and multiply inside living hosts, such as animals and humans. (medicalnewstoday.com)
  • Viruses are minuscule - 45,000 times smaller than the width of a human hair. (medicalnewstoday.com)
  • But while there are many types of viruses in the world, only some are known to cause illness in humans. (medicalnewstoday.com)
  • Selvaraju SB, Kovac M, Dickson LM, Kajon AE, Selvarangan R. Molecular epidemiology and clinical presentation of human adenovirus infections in Kansas City children. (childrensmercy.org)
  • We tested the possibility of interfering with apoptotic photoreceptor cell death in the rd mouse through subretinal delivery of a recombinant replication-defective adenovirus containing the human cDNA for bcl-2, Ad.2.5HRPbcl-2. (nih.gov)
  • During the first incubation, adenovirus antigens present in the stool supernatant are captured by antibodies attached to the wells. (rapidtest.com)
  • daughter of AQ-1, had a febrile respiratory infection with Human Adenovirus Type 55 cough. (cdc.gov)
  • In comparison with the Ad14 patients, among the 12 adenovirus non-type 14 patients (i.e., all but three) whose medical charts were reviewed, nine (75%) were male. (cdc.gov)
  • Gene and mRNA for precursor polypeptide VI from adenovirus type 2. (microbiologyresearch.org)
  • Genetic analysis of adenovirus type 2. (microbiologyresearch.org)
  • According to surveillance reports submitted to the US Centers for Disease Control and Prevention's (CDC) National Adenovirus Type Reporting System, nearly 2400 cases of human adenovirus were reported in the 50 states between 2006 and 2016, the most recent period for which data are available. (contagionlive.com)
  • The authors emphasized that all 4 of the fatalities in this case cluster occurred in patients over 50 years of age with preexisting co-morbidities (eg, congestive heart failure, hepatic cirrhosis, alcohol use disorder, and type 2 diabetes), although human adenovirus-7d has been associated with severe illness and higher fatality rates compared to other types, particularly in children. (contagionlive.com)
  • Recovery from adenovirus infection is associated with the development of serotype-specific neutralizing antibodies. (medscape.com)
  • Nevertheless, the high prevalence of Advertisement5-particular neutralizing antibodies (NAb) in human being populations, in sub-Saharan Africa especially, gets the potential to limit the potency of Advertisement5-centered vaccines (23, 27C30). (synanet2020.com)
  • Diagnostic Automation Adenovirus ELISA test kit is an in vitro procedure for the qualitative determination of adenovirus antigen in feces. (rapidtest.com)
  • Adenoviruses are immunogenic and elicit strong innate and adaptive immune responses. (medscape.com)
  • Adenovirus also was isolated by culture, confirmed by immunofluorescence assay (IFA), and typed as Ad14 by antibody neutralization assay. (cdc.gov)
  • The Qinghai adenovirus strain(QH-1665/2018) was isolated from an outpatient, whom was one month old and diagnosed with an influenza-like illness at Women's and Children's Hospital of Qinghai Province on November 26, 2018. (biomedcentral.com)
  • Scientists use a modified version of one of these adenoviruses, known as a vector, to deliver important instructions to cells, according to the US Centers for Disease Control (CDC) . (bbc.com)
  • Their adenovirus vector contains mutant DNA polymerase (dNTP) that should activate only in cells with a high concentration of dNTP, such as cancer cells. (sciencedaily.com)
  • Genes within the E3 transcription unit of human adenoviruses modulate host immune responses to infection . (bvsalud.org)
  • QH-1665/2018 caused adenovirus-like CPE of HEp-2 cells, and the cultures underwent three passages to obtain high-titer stocks. (biomedcentral.com)
  • BACKGROUND: In 2007, a US Air Force training facility reported a cluster of severe respiratory illnesses associated with a rare human adenovirus (Ad) serotype, Ad14. (itg.be)
  • These findings are discussed in relation to the role of pVI in triggering the adenovirus maturation pathway. (microbiologyresearch.org)
  • Case clusters of severe respiratory disease, caused by specific adenoviruses (particularly types 7, 14, and 55), have occurred in healthy adults. (msdmanuals.com)
  • Adenovirus, a DNA virus, was first isolated in the 1950s in adenoid tissue-derived cell cultures, hence the name. (medscape.com)
  • An extremely hardy virus, adenovirus is ubiquitous in human and animal populations, survives long periods outside a host, and is endemic throughout the year. (medscape.com)
  • The adenovirus protease is activated by a virus-coded disulphide-linked peptide. (microbiologyresearch.org)
  • 1953) isolated a new virus from cultures of human adenoids. (cabi.org)
  • Latent infection with adenovirus and respiratory syncytial virus (RSV) is associated with chronic obstructive pulmonary disease (COPD). (spandidos-publications.com)
  • Human adenovirus, a DNA virus, is associated with respiratory infections and smoking-induced lung function impairment ( 2 , 3 ). (spandidos-publications.com)
  • These human observations are supported by experiments in guinea pigs, where, in the absence of actively replicating virus but the presence of E1A DNA, adenovirus infection resulted in excess lung inflammation following a single exposure to cigarette smoke 7 , and increased parenchymal and airway wall inflammation with greater emphysematous destruction after chronic exposure 8 . (ersjournals.com)
  • In a new study, the researchers redesigned the human adenovirus so that the virus is not easily captured by a part of the innate immune system. (sooperarticles.com)
  • One popular oncolytic virus is Adenovirus, in which serotype modifications are directly made to the virus' fiber used for attachment to host cells. (kzoo.edu)
  • Scientists are testing a new innovation in biotherapy by altering a common childhood respiratory virus, the adenovirus, to destroy cancer cells. (sciencedaily.com)
  • Expression of TAP1 is down-regulated by human Epstein-Barr virus vil-10 protein, thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. (lu.se)
  • Sewage samples from 14 sewage disposal systems in Poland (located in 13 towns) were examined for the presence of adenoviruses by molecular methods. (pjmonline.org)
  • Adv infects the host cells through binding to different cellular receptors such as coxsackievirus and adenovirus receptor (CAR) [ 12 ]. (hindawi.com)
  • The aim of the present study was to investigate the prevalence of adenovirus and RSV A and B among patients with COPD-AE and those in a stable condition. (spandidos-publications.com)
  • See the Adenovirus ELISA Kit product insert for details on preparation, procedures, quality control, and test result interpretation. (rapidtest.com)
  • Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea. (ox.ac.uk)
  • In this study, we have examined the feasibility of gene transfer to human corneal endothelium, using a number of recombinant adenovirus constructs. (ox.ac.uk)
  • View cart "h SOX2 expression Adenovirus, in vivo ready" has been added to your cart. (gentarget.com)
  • However, its widespread application is hampered by difficulties in large-scale production of the native protein from human plasma and/or availability as a recombinant protein suitable for use in vivo. (nebraska.edu)
  • In this study, recombinant (r) adenoviruses (Ads) encoding full-length and truncated rHu BChEs were tested for in vivo expression in mice. (nebraska.edu)
  • The knockdown of this human gene was validated by qPCR in A549 cells. (vectorbiolabs.com)
  • Additional information on adenovirus testing at CDC is available at Submitting Specimens to CDC . (cdc.gov)
  • Before collecting any specimens, discuss with a laboratory and a clinician familiar with adenovirus. (cdc.gov)