• systemic
  • Elevated lactic acid levels have also been observed in individuals who are not septic and who are normotensive, but who have received systemic adrenergic agonist therapy. (hindawi.com)
  • Mitochondria
  • In such cases, when the body needs more energy than usual, for example during exercise or disease, mitochondria cannot match the cells' demand for ATP, and lactic acidosis results. (wikipedia.org)
  • Also, muscle types that have few mitochondria and preferentially use glycolysis for ATP production (fast-twitch or type II fibers) are naturally prone to lactic acidosis. (wikipedia.org)
  • cerebrospinal fluid
  • Whereas some individuals may have persistently elevated levels of lactic acid in blood, cerebrospinal fluid and urine, other persons may have only occasional increases in lactic acid that are brought on by another illness, such as an infection, a seizure or an asthmatic attack. (rarediseases.org)
  • bicarbonate
  • To the editor: In his recent letter (1), critical of our support (2) for bicarbonate therapy of keto and lactic acidosis, Hollander straddles the horns of an uncomfortable dilemma. (annals.org)
  • diagnosis
  • There were 10 subjects who had hospital discharges with a diagnosis of acidosis. (diabetesjournals.org)
  • The pathophysiology, causal classification, and diagnosis of lactic acidosis are reviewed. (annals.org)
  • The diagnosis is made on biochemical analysis of blood (often initially on arterial blood gas samples), and once confirmed, generally prompts an investigation to establish the underlying cause to treat the acidosis. (wikipedia.org)
  • urine
  • GRACILE is an acronym for growth retardation, amino aciduria (amino acids in the urine), cholestasis, iron overload, lactic acidosis, and early death. (wikipedia.org)
  • Citation
  • citation needed] Ketogenic diets, with high fat and low carbohydrate intake have been used to control or minimize lactic acidosis and anecdotal evidence shows successful control of the disease, slowing progress and often showing rapid improvement. (wikipedia.org)