• Parasites
  • During the current funding period, we have characterized a major virulence protein of Acanthamoeba, the mannose-binding protein (MBP) that mediates the adhesion of parasites to host cells. (grantome.com)
  • organisms
  • We are hopeful that the proposed studies will help develop novel, rationally designed strategies to manage and protect against: (i) AK in the short run, and (ii) keratitis produced by other organisms in the long run. (grantome.com)
  • characteristics
  • Specifically, we have cloned and characterized the Acanthamoeba MBP and have shown that it is a transmembrane protein with characteristics of a typical cell surface receptor. (grantome.com)