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  • study
  • No immunogenicity analyses were performed because the results from a previous study, V520-023 (NCT00095576), which used the same vaccine as the one used in this study (NCT00849680) proved it was not efficacious. (clinicaltrials.gov)
  • Primate Research Laboratories study chimpanzees and monkeys to answer AIDS vaccine-related questions. (nih.gov)
  • influenza
  • He is known for his researches in the fields of protein structure and protein folding and his contributions in developing vaccines and drugs for treating a type of fatal influenza and HIV-1. (wikipedia.org)
  • Despite the fact that this killed whole virus strategy is widely exercised to prevent diseases like polio, influenza, cholera, mumps, rabies, typhoid fever and hepatitis A in the past, it failed to receive any serious attention in the effort to develop vaccines against HIV for various scientific, economical and technical reasons. (wikipedia.org)
  • monkeys
  • Primate research laboratories answer HIV vaccine-related questions by testing HIV and HIV-like vaccines in chimpanzees and monkeys. (nih.gov)
  • In tests in 24 rhesus monkeys at Yerkes, the vaccine successfully contained a highly virulent hybrid of simian and human immunodeficiency viruses (SHIV). (emory.edu)
  • Fourth, the early studies with the monkeys using the killed simian immunodeficiency virus (SIV) vaccine showed some optimism but it turned out that the protection was attributable to responses to both the cellular proteins on the SIV vaccine and on the challenge virus grown not in monkey cells but in human cells. (wikipedia.org)
  • development
  • National Cooperative Vaccine Development Groups (NCVDGs) represent the core HIV vaccine discovery and development effort sponsored by NIAID. (nih.gov)
  • Master Contracts for Preclinical HIV Vaccine Development provide flexible resources for the preclinical development of the most promising HIV vaccine candidates. (nih.gov)
  • These resources include vaccine production, preclinical evaluation of vaccines in nonhuman primates and the development of biological and chemical substances called reagents for use in comparative vaccine studies. (nih.gov)
  • Most likely we will have to have a third trial to test the combined regimen of the DNA and booster portions of the vaccine," said Harriet Robinson, chief of the Yerkes Division of Microbiology and Immunology, who led the development of the vaccine. (emory.edu)
  • As a result, a number or riders and volunteers gathered together to form a volunteer organization whose purpose is to forward the cause of AIDS awareness and raise funds for vital research in the development of a vaccine. (wikipedia.org)
  • It also partners with civil society organizations and other entities to advocate jointly for the development of AIDS vaccines, and is a member of the Global Health Technologies Coalition, an alliance of more than 30 non-profit groups that aims to increase awareness of the urgent need for technologies that save lives in developing countries. (wikipedia.org)
  • citation needed] In June 2009, SAAVI announced that it was testing a new HIV vaccine candidate but suspended all further vaccine development indefinitely due to lack of funds. (wikipedia.org)
  • the development of vaccines against Hepatitis A and membership of the International Task Force for Hepatitis B Immunization. (wikipedia.org)
  • AIDS Vaccine Development: Challenges and Opportunities. (wikipedia.org)
  • In interviews, Ertl has been cautious and critical when it comes to the development of vaccines for AIDS. (wikipedia.org)
  • As Executive Director, Bernstein oversaw the Enterprise Secretariat in implementing activities to support the goals and mission of the Enterprise, including the development of the 2010 Scientific Strategic Plan for HIV vaccine development and facilitating and integrating the activities of the Enterprise partners to ensure their effective implementation of the Enterprise Scientific Strategic Plan. (wikipedia.org)
  • 2002
  • Action Cycling Atlanta, Inc. (ACA) was formed in 2003 by a group of cyclists who had participated in the 2002 European AIDS Vaccine Ride, one of the last AIDSRides produced by Pallotta Teamworks. (wikipedia.org)
  • novel
  • Teams of scientists from industry, academia and government collaborate to develop and test novel experimental HIV vaccine concepts in the laboratory and in animal models. (nih.gov)
  • epidemic
  • There has been such widespread homophobia in the wake of the AIDS epidemic that it is important for the general population to appreciate that among a substantial number of homosexuals there is a strong sense of compassion and responsibility. (latimes.com)
  • They acknowledge and thank the thousands of volunteers, community members, health professionals, supporters and scientists who are working together to find a safe and effective AIDS vaccine and urge the international community to recognize the importance of investing in new technologies as a critical element of a comprehensive response to the HIV/AIDS epidemic. (wikipedia.org)
  • 2006). Ending an epidemic: the International AIDS Vaccine Initiative pioneers a public-private partnership. (wikipedia.org)
  • beneficiaries
  • Fundraising Results by Year The big wheel / Critics don't faze Dan Pallotta, who has helped raise big bucks for AIDS research - and his company Pallotta announces end to AIDS Vaccine Rides: Even with production fee forfeited, beneficiaries to receive less than 10 percent Archived May 25, 2011, at the Wayback Machine. (wikipedia.org)
  • antibodies
  • However, more than a third of those surveyed, 273 men in all, responded that they are willing both to be tested and to volunteer if they are determined not to be carrying antibodies to the AIDS virus. (latimes.com)
  • Vaccines work by exposing the body to the disease-causing agent or a fragment of it, which primes the immune system to produce a flood of antibodies that stick to the infecting organism and block it from entering cells. (scientificamerican.com)
  • Potent Antibodies Spark Vaccine Hopes. (wikipedia.org)
  • The study was completed in August 2013 and reported no serious adverse effects while boosting antibodies in the volunteers injected with SAV001-H vaccines. (wikipedia.org)
  • 2000
  • He received a number of research fellowships which included the Swarnajayanthi Fellowship for Biological Sciences of the Department of Science and Technology and AIDS-Innovation Grant Award of the National Institutes of Health ( both in 1999), Senior Research Fellowship of Wellcome Trust (2000) and the J. C. Bose National Fellowship of the Department of Science and Technology (2007-12). (wikipedia.org)
  • Volunteers
  • Pending final approval of the trial by institutional review boards, 30 human volunteers at three sites around the country will begin receiving the vaccine within the next several months. (emory.edu)
  • The trial will compare the effects of high and low dosages of the vaccine in two groups of (HIV negative) volunteers, who will receive two intramuscular injections. (emory.edu)
  • The riders and volunteers were committed to the cause of raising the public awareness about AIDS, and felt compelled to not let this be a one-time event. (wikipedia.org)
  • hopes
  • By late 2004, the Vaccine Center hopes to begin a Phase I trial of a trivalent vaccine incorporating the DNA from clades B, AG, and C. Subtype C is the most prevalent form of HIV in India and southern Africa. (emory.edu)
  • Clinic
  • The Emory Vaccine Center's Hope Clinic will serve as one of the clinical test sites for this trial. (emory.edu)
  • The ride originally traveled from the Hope Clinic in Decatur, GA to Athens, GA. To accommodate more riders, in 2007, ride organizers changed the route to begin and end on the Emory University campus with a Saturday night stay at Rock Eagle near Eatonton, GA. In 2009, the name of the ride was changed to the AIDS Vaccine 200 to communicate more clearly the purpose of the ride. (wikipedia.org)
  • virology
  • If virology ever gets to the point they can create a safe and reliable vaccine to treat virus' the world would be better served by a common cold vaccination. (newser.com)
  • He established the National HIV reference laboratory and directed the National Health and Medical Research Council's special unit for AIDS virology. (wikipedia.org)
  • laboratories
  • Collaborating with Merck Research Laboratories on behalf of Jawaharlal Nehru Centre for Advanced Scientific Research, his team developed a number of immunogens which have been demonstrated to have positive effect as HIV-1 vaccines and he holds the patent for the invention. (wikipedia.org)
  • Ertl said that the vaccines the laboratories in the center are developing "have important implications for public health because they can reduce disease and death from very common infections. (wikipedia.org)
  • evaluate
  • and * to promptly evaluate promising candidate vaccines in animal models and, if warranted, in humans. (nih.gov)
  • The groups also develop new adjuvant formulations and evaluate vaccine-adjuvant combinations in relevant animal models. (nih.gov)
  • effective
  • Currently, even the "cocktail treatment", the most effective measure to deal with AIDS so far, can only stabilize or ease the AIDS symptoms instead of killing the virus in the body. (chinadaily.com.cn)
  • National Instit
  • To help reach this goal, the National Institute of Allergy and Infectious Diseases (NIAID), which spearheads federal funding for biomedical research on HIV/AIDS for the National Institutes of Health (NIH), has intensified its HIV vaccine research program. (nih.gov)
  • develop
  • Ten years ago today, President Bill Clinton announced a national goal to develop an AIDS vaccine within a decade. (scientificamerican.com)
  • But with the strides of recent years, it is no longer a question of whether we can develop an AIDS vaccine, it is simply a question of when . (scientificamerican.com)
  • Many of these patients have been HIV positive for 30 years without progressing to the point of needing to take medication in order not to develop AIDS. (wikipedia.org)
  • The classification "Long-term non-progressor" is not permanent, because some patients in this category have gone on to develop AIDS. (wikipedia.org)
  • These patients, however, are not typically classified as LTNPs, but rather as slow progressors, who will eventually develop AIDS. (wikipedia.org)
  • test
  • As Dr. Lawrence K. Altman wondered earlier this year, who will test such a vaccine? (latimes.com)
  • Dr. Leon McKusick, a psychologist with the University of California at San Francisco, has surveyed 644 homosexual men about their willingness to participate in a test of an AIDS vaccine. (latimes.com)
  • Many of those surveyed by McKusick have not taken the antibody test--a blood test that indicates if the subject has been exposed to AIDS. (latimes.com)
  • Human body test, or stage I clinical test, of the compound AIDS vaccine aims to further assess the security of the vaccine, an SFDA official said. (chinadaily.com.cn)
  • international
  • Funders include The Bill and Melinda Gates Foundation, the Ford Foundation, the International AIDS Vaccine Initiative, Until There's a Cure Foundation, Broadway Cares/Equity Fights AIDS, the Gill Foundation, and the Overbrook Foundation. (wikipedia.org)
  • Merck have tested the a few vaccines and some of the other proposals are being tested by International AIDS Vaccine Initiative. (wikipedia.org)
  • human
  • AIDS is a peculiarly human disease. (latimes.com)
  • Chinese-developed AIDS vaccine has won government approval to be tested by human bodies, Xinhua reported Friday quoting sources with the State Food and Drug Administration (SFDA) of China. (chinadaily.com.cn)
  • Zinc finger nucleases have also been used in a mouse model of haemophilia and a clinical trial found CD4+ human T-cells with the CCR5 gene disrupted by zinc finger nucleases to be safe as a potential treatment for HIV/AIDS. (wikipedia.org)