• acquired immunode
  • It was usually observed in the late stages of acquired immunodeficiency syndrome (AIDS), when CD4 + lymphocyte counts fall below 200 cells/mL, and was seen in up to 50% of patients prior to their deaths. (medscape.com)
  • Alzheimer's
  • While the degenerative dementias characteristically affect older patients, they are also an important cause of YOD: indeed, Alzheimer's disease is the commonest single cause of YOD with an estimated 3000 cases in the United Kingdom, followed by vascular dementia and the frontotemporal lobar degenerations (table 1). (bmj.com)
  • Topographical disorientation may result from a stroke or part of a progressive illness, hemispatial neglect, dementia, Alzheimer's disease. (wikipedia.org)
  • Infections
  • When the CD4 lymphocyte count falls below 200 cells/ml of blood, the HIV host has progressed to AIDS, a condition characterized by deficiency in cell-mediated immunity and the resulting increased susceptibility to opportunistic infections and certain forms of cancer. (wikipedia.org)
  • Phase
  • In 2005, the ACTG opened its first multinational AIDS clinical trial in 16 sites around the globe "A Phase IV, Prospective, Randomized, Open-Label Evaluation of the Efficacy of Once-Daily PI & Once-Daily Non-Nucleoside Reverse Transcriptase Inhibitor - Containing Therapy Combinations for Initial Treatment of HIV-1 Infected individuals from Resource - Limited Settings (PEARLS) Trial", the results of which suggested men and women respond to antiretroviral drugs differently. (wikipedia.org)
  • cognitive
  • Individuals with AIDS frequently suffer central nervous system (CNS) problems that are characterized by cognitive, motor, and behavioral deficits, in a disorder known as AIDS dementia complex. (clinicaltrials.gov)
  • Dementia is very rare before the age of 40: in young adults and adolescents, genetic and metabolic disorders predominate and many present as a "dementia-plus" syndrome, where cognitive impairment occurs in the setting of more widespread neurological disturbance. (bmj.com)
  • 6 Many of the dementia-plus syndromes and metabolic disorders have "subcortical" cognitive impairment that may be misinterpreted as a pseudodementia. (bmj.com)
  • Cognitive impairments identified in 1 do not meet the criteria for delirium, or if delirium is present, dementia was diagnosed when delirium was not present. (wikipedia.org)
  • cerebrospinal fluid
  • The effect of d4T-containing regimens is assessed for the following parameters: neurological status, survival, AIDS-defining conditions, CSF (cerebrospinal fluid) and plasma viral load, CSF and blood immunological markers, blood CD4 cell counts, and viral resistance. (clinicaltrials.gov)
  • mechanisms
  • The amount of virus in the brain does not correlate well with the degree of dementia, suggesting that secondary mechanisms are also important in the manifestation of ADC. (wikipedia.org)
  • However, gliosis has been shown to have both beneficial and detrimental effects, and the balance between these is due to a complex array of factors and molecular signaling mechanisms, which affect the reaction of all glial cell types. (wikipedia.org)
  • occurs
  • It occurs after the incubation stage, before the latency stage and the potential AIDS succeeding the latency stage. (wikipedia.org)
  • people
  • People with AIDS also have an increased risk of developing various cancers such as Kaposi's sarcoma, cervical cancer and cancers of the immune system known as lymphomas. (wikipedia.org)
  • Studying these people will aid in the understanding of the complex, multi-component behavior of navigation. (wikipedia.org)
  • Glossary
  • This is a list of AIDS-related topics, many of which were originally taken from the public domain U.S. Department of Health Glossary of HIV/AIDS-Related Terms, 4th Edition. (wikipedia.org)