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  • nucleotides
  • Results: A novel variable number of tandem repeat (VNTR) polymorphism in the 5'-flanking region (-1241 nucleotides from the major transcriptional initiation site) was discovered. (medsci.org)
  • The fact that AAV has evolved to integrate into this ubiquitously transcribed region and that the chromosomal motifs required for integration are located a few nucleotides upstream of the translation initiation start codon of MBS85 suggests that the transcriptional activity of MBS85 might influence site-specific integration and thus might be involved in the evolution of this mechanism. (pubmedcentralcanada.ca)
  • The numbering scheme for nucleotide positions is based on assignment of the (+1) position to the "A" in the translation initiation codon, with nucleotides 5′ to that position assigned negative and those 3′ within the cDNA assigned positive numbers. (aacrjournals.org)
  • genes
  • Cordes S, Deikman J, Margossian LJ, Fischer RL: Interaction of a developmentally regulated DNA-binding factor with sites flanking two different fruit-ripening genes from tomato. (springer.com)
  • human
  • In the absence of such helper functions, AAV-2 establishes latency by site-specifically integrating its genome into a region of human chromosome 19 (19q13.42) termed AAVS1 ( 27 - 30 , 51 ). (pubmedcentralcanada.ca)
  • receptor
  • 1 , 3 , 5 Animal models became resistant to the induction of EAMG when circulating complement was either depleted by cobra venom toxin or functionally inhibited by the administration of a monoclonal C5 antibody or soluble C1 receptor. (pubmedcentralcanada.ca)
  • Chromosome
  • Here, we present a method for rapid manipulation of the V. cholerae chromosome(s) 5 ( Figure 1 ). (jove.com)
  • contains
  • The cDNA contains an open reading frame (ORF) of 1449 bp that encodes 483 amino acid residues and 126- and 296-bp non-coding regions at the 5′- and 3′-ends, respectively. (mdpi.com)
  • Several lines of evidence suggest that AAVS1 contains a transcriptionally active region. (pubmedcentralcanada.ca)
  • Its heavy chain contains two fibronectin-type domains (type I and II), two epidermal growth factor-like domains, a kringle domain, and a proline-rich region, and its light chain contains the protease domain. (wikipedia.org)
  • enzyme
  • Adjacent to the C-terminal TSR is a disintegrin-like domain, a cysteine-rich region that stacks against the active-site of the enzyme when in its final folded tertiary structure. (wikipedia.org)
  • Cell
  • By use of electrophoretic mobility shift assays with rat aortic smooth muscle cell nuclear extracts, Sp1 and Sp3 transcription factors bound to this region, and transfection assays in D.Mel.2 cells revealed that both Sp1 and Sp3 transactivated the ACLP promoter. (ahajournals.org)
  • repeat
  • Kosuge K, Soma M, Nakayama T, Aoi N, Sato M, Izumi Y, Matsumoto K. A Novel Variable Number of Tandem Repeat of the Natriuretic Peptide Precursor B gene's 5'-Flanking Region is Associated with Essential Hypertension among Japanese Females. (medsci.org)