Identifying 'non-medical' datasets to monitor community health and well-being.
(49/709)
BACKGROUND: The aim of the study was to identify 'non-medical' datasets holding routinely collected information that might be used to measure and monitor the wider determinants of community health and well-being. METHODS: An expert panel discussion, involving public health and environmental health academics and professionals with expertise in a variety of backgrounds (including environmental health, housing, transport, community safety, public health, primary and secondary care), and interrogation of the Office for National Statistics database were carried out for the West Midlands region. The aim was to identify routinely collected 'non-medical' datasets containing information on the following factors: physical environment, crime, housing and homelessness, social services, socio-economic environment including employment, lifestyles, education, leisure and culture, transport and accidents. RESULTS: Fifty-six datasets were identified. Although 43 (77 per cent) were collected at least annually, few (17; 30 per cent) held data that were disaggregated and routinely available at the sub-local authority level. CONCLUSIONS: This study has identified a number of datasets that hold information relevant to health. However, no single dataset is likely to provide information on all dimensions of health and the determinants of health, and local agencies should consider carefully the strengths and weaknesses of each. Through the development of inter-sectoral working and multi-agency involvement at the local level there is now considerable scope to improve the quality of many of these datasets and to promote their use in the measurement and monitoring of community health. (+info)
Correlation between serum IL-6 levels and death: usefulness in diagnosis of "traumatic shock"?
(50/709)
Interleukin-6 (IL-6) has been considered as an important mediator of inflammation. Clinically it is a well-known marker of the severity of injury following major trauma. In this study, the levels of IL-6 in body serum were applied to a traumatic death index. Of ninety victims 55 were men and 35 women, with a mean age of 53.4+/- 19 (S.D.) years. The cases were classified as traumatic deaths (38 cases), non-traumatic deaths other than natural causes of deaths (36 cases), and deaths due to natural causes (16 cases). All samples were collected within 2 days after death. The mean values of IL-6 levels of the traumatic, non-traumatic and disease groups were 8608.97, 2205.65, and 3266.64 pg/ml, respectively. Some cases in non-traumatic and disease cases were beyond 10 000 pg/ml, however, the mean value of the traumatic group was statistically higher than that of the other two groups. Even though several cases had high levels of IL-6 in spite of instantaneous death, the results showed that IL-6 levels are helpful in the diagnosis of traumatic shock. (+info)
Two cases of sodium azide poisoning by accidental ingestion of Isoton.
(51/709)
Accidental ingestion of sodium azide in 0-1% solution by a patient and a laboratory technician in a haematological laboratory has demonstrated that very small quantities of sodium azide can give rise to toxic symptoms and that Isoton should be handled with care. (+info)
Carotid sinus hypersensitivity is common in older patients presenting to an accident and emergency department with unexplained falls.
(52/709)
OBJECTIVE: To determine the prevalence of carotid sinus hypersensitivity and orthostatic hypotension in older patients with non-accidental falls attending an accident and emergency department. DESIGN: A prospective case-control non-randomized study. Data were collected from semi-structured interviews, physical examination and neurocardiovascular investigations. SETTING: We recruited cases and controls from an inner-city accident and emergency department. PARTICIPANTS: 26 consecutive patients presenting to accident and emergency with non-accidental falls and 54 controls matched for age, sex and cognitive function presenting to the same department either because of an accidental fall or a reason other than falling. MAIN VARIABLES MEASURED: Detailed history and clinical evaluation, including postural phasic blood pressure measurements, heart rate and blood pressure responses to supine and upright carotid sinus stimulation. RESULTS: Orthostatic blood pressure responses did not differ between groups. The heart rate and blood pressure responses to carotid sinus massage were abnormal in patients with non-accidental falls compared with controls (P=0.002). Asystolic responses were present in 12 (46%) of 26 cases and seven (13%) of 54 controls. Loss of consciousness occurred during carotid sinus massage in seven (27%) of the cases, all of whom had asystole, and in none of the controls. CONCLUSIONS: Almost half of the cognitively normal older patients attending accident and emergency with non-accidental falls have carotid sinus hypersensitivity, emphasizing that a post-fall intervention strategy should include carotid sinus studies. (+info)
Intensive care management of organophosphate insecticide poisoning.
(53/709)
INTRODUCTION: Organophosphate (OP) insecticides inhibit both cholinesterase and pseudo-cholinesterase activities. The inhibition of acetylcholinesterase causes accumulation of acetylcholine at synapses, and overstimulation of neurotransmission occurs as a result of this accumulation. The mortality rate of OP poisoning is high. Early diagnosis and appropriate treatment is often life saving. Treatment of OP poisoning consists of intravenous atropine and oximes. The clinical course of OP poisoning may be quite severe and may need intensive care management. We report our experience with the intensive care management of serious OP insecticide poisonings. METHODS: A retrospective study was performed on the patients with OP poisoning followed at our medical intensive care unit. Forty-seven patients were included. Diagnosis was performed from the history taken either from the patient or from the patient's relatives about the agent involved in the exposure. Diagnosis could not be confirmed with serum and red blood cell anticholinesterase levels because these are not performed at our institution. Intravenous atropine and pralidoxime was administered as soon as possible. Pralidoxime could not be given to 16 patients: 2 patients did not receive pralidoxime because they were late admissions and 14 did not receive pralidoxime because the Ministry of Health office was out of stock. Other measures for the treatment were gastric lavage and administration of activated charcoal via nasogastric tube, and cleansing the patient's body with soap and water. The patients were intubated and mechanically ventilated if the patients had respiratory failure, a depressed level of consciousness, which causes an inability to protect the airway, and hemodynamic instability. Mechanical ventilation was performed as synchronized intermittent mandatory ventilation + pressure support mode, either as volume or pressure control. Positive end expiratory pressure was titrated to keep SaO2 above 94% with 40% FIO2. Weaning was performed using either T-tube trials or pressure support weaning. The chi-square test was used for statistical analysis. Data are presented as mean +/- standard deviation. RESULTS: There were 25 female and 22 male patients. Thirty-two (68%) were suicide attempts and 15 (32%) were accidental exposure. The gastrointestinal route was the main route in 44 (93.6%) patients. The mortality rates for the patients who did and did not receive pralidoxime were 32 and 18.7%, respectively, and were not statistically different. The most frequent signs were meiosis, change in mental status, hypersalivation and fasciculations. Ten patients (21.2%) required mechanical ventilation. The mortality rate for the patients who required mechanical ventilation was 50%, but the rate was 21.6% for the patients who were not mechanically ventilated. Intermediate syndrome was observed in 9 (19.1%) patients. Complications were observed in 35 (74.4%) patients. These complications were respiratory failure (14 patients), aspiration pneumonia (10 patients), urinary system infection (6 patients), convulsion (4 patients) and septic shock (1 patient). The duration of the intensive care stay was 5.2 +/- 3.0 days. DISCUSSION: Ingestion of OP compounds for suicidal purposes is a major problem, especially in developing countries. Thirty-two (68%) of our patients used the OP insecticide for suicide. Two patients did not receive pralidoxime because of delayed admission and they were successfully treated with atropine alone. Three of the patients who did not receive pralidoxime because of unavailability died. The mortality rate was no different between the patients treated with pralidoxime or those without pralidoxime. De Silva and coworkers have also reported that the mortality rate was not different between each group. Three patients with intermediate syndrome died due to delay for endotracheal intubation. The average respiratory rate of these patients increased from 22 to 38 breaths/min, which is an important sign of respiratory distress. The nurse to patient ratio was increased after these events. Early recognition of respiratory failure resulting in intubation and mechanical ventilation is a life-saving intervention for patients with OP poisoning. Respiratory failure is the most troublesome complication, which was observed in 35 (74.4%) patients. Patients with OP poisoning may have respiratory failure for many reasons, including aspiration of the gastric content, excessive secretions, pneumonia and septicemia complicating acute respiratory distress syndrome. CONCLUSIONS: OP insecticide poisoning is a serious condition that needs rapid diagnosis and treatment. Since respiratory failure is the major reason for mortality, careful monitoring, appropriate management and early recognition of this complication may decrease the mortality rate among these patients. (+info)
Older people in accident and emergency departments.
(54/709)
Older people attend accident and emergency departments more frequently than younger people. However, most assessments indicate that this higher level of use is appropriate and is the result of more serious injury and illness among this population. Older patients discharged from accident and emergency departments are frequently functionally impaired with serious impacts upon their ability to perform activities of daily living. Despite this, relatively little attention has been paid to interventions to improve older patients' ability to self-care after discharge from accident and emergency departments. One study has suggested that dependency can be reduced by health visitor intervention. Targeted bi-disciplinary interventions have been demonstrated to reduce the risk of recurrent falls in elderly patients discharged from accident and emergency departments. (+info)
Morbidity patterns of non-urgent patients attending accident and emergency departments in Hong Kong: cross-sectional study.
(55/709)
OBJECTIVES: To study the morbidity patterns of non-urgent patients utilising accident and emergency services and compare these patients with 'true' accident and emergency cases. To analyse the morbidity pattern of non-urgent cases over different time periods, and across different age groups. DESIGN: A cross-sectional study completed over a 1-year period. SETTING: Four accident and emergency departments in Hong Kong. PATIENTS: Two thousand, four hundred and ten patients randomly selected from four accident and emergency departments. MAIN OUTCOME MEASURES: The morbidity patterns by body system, according to the International Classification of Primary Care, were tabulated and analysed for 'true' accident and emergency cases versus non-urgent cases. The ten most frequent diagnoses for the 'true' accident and emergency and non-urgent cases were also compared. Further analysis of accident and emergency service utilisation was conducted comparing different age groups, and also different time periods. RESULTS: Significantly more cases presenting to the accident and emergency service with respiratory and digestive problems were found to be non-urgent, rather than appropriate accident and emergency cases. In contrast, significantly more cases presenting with circulatory and neurological problems were appropriate cases for accident and emergency department management. The morbidity pattern for the ten most frequent diagnoses seen in non-urgent cases was noted to be similar to the Hong Kong general practice morbidity pattern for self-limiting conditions. Utilisation of accident and emergency services for acute self-limiting conditions was more marked in the late evening, and also among children and the younger population in general. CONCLUSION: The utilisation of accident and emergency services by patients requiring a general practice service only, reflects problems in the primary health care delivery system. These may be solved by appropriate interfacing between general practitioners and other service providers, with the aim of providing seamless health care. Without revision of primary health care services, accident and emergency departments will continue to be used inappropriately by patients as an alternative to general practice care. (+info)
Banning the "A word": where's the evidence?
(56/709)
BACKGROUND: It is argued that use of the term "accident" has a negative effect on prevention efforts as the term implies that such events are due to chance. AIM: To test the hypothesis that use of "injury" in place of "accident" can influence professional attitudes towards "accident/injury" prevention. SETTING: Leeds Health Authority area serving the population (n=740,000) of the city of Leeds in the Yorkshire region of England. METHOD: A randomised comparative study. Altogether 183 health visiting staff in the Leeds area were randomised (by place of work) to one of two groups. Each group received a similar postal questionnaire assessing attitudes relating to accident/injury prevention. One group received a questionnaire using only accident terminology while the other used injury terminology throughout. RESULTS: Fifty responses in the accident group were received and 39 in the injury group. Analysis by Mann-Whitney U tests showed little difference in group responses. The only significant finding was that respondents in the "accident" group were more likely to rank "accident prevention" of higher importance relative to respondents in the "injury" group (median 2, 25%-75% quartiles 1.8-4.0 compared with median 4, 25%-75% quartiles 2.0-5.0, p=0.04). However, this may have been a chance finding due to the multiple comparisons made. CONCLUSIONS: This study has shown little difference in health visitor responses when "accident" is replaced with "injury". It is possible that the effect of changing terminology is more nebulous--influencing society at large. However, it would be as well to recognise the lack of evidence and clarity relating to the terminology debate. Otherwise, there is a danger that the "injury" believers may become alienated from the "accident" diehards. (+info)