Hao S, Lv J, Yang Q, Wang A, Li Z, Guo Y, Zhang G (April 2019). "Identification of Key Genes and Circular RNAs in Human Gastric ... In triple-negative breast cancer cells, immuno-activation by tumor necrosis factor alpha (TNFα) was found to up-regulate ... which typically has a better prognosis. In renal cancer, high expression of TMEM171 is a favorable prognostic marker. ... Dezso Z, Nikolsky Y, Sviridov E, Shi W, Serebriyskaya T, Dosymbekov D, et al. (November 2008). "A comprehensive functional ...
The median age at diagnosis in a study of 138 women was 67 years, of these 54 had stage I, 20 stage II, 41 stage III, and 23 ... Prognosis of uterine papillary serous carcinoma is affected by age, stage, and histology as well as treatment. Gründker C, ... The antibody trastuzumab (Herceptin), which is used to treat breast cancers that overexpress the HER2/neu protein, has been ... In 2009, the journal of "Gynecologic Oncology" reported the following 5-year survival rates based upon stage of cancer: Stage I ...
Antibodies are Y-shaped which allows them to work properly because that is how their unique sites bind with a matching site on ... The prognosis is difficult to evaluate given the rarity of this condition, some patients with autoimmune oophoritis may have ... A few risk factors associated with the hormone replacement therapies are: breast cancer, endometrial cancer, and ovarian cancer ... N. Y. Acad. Sci. 1135 (1): 118-22. Bibcode:2008NYASA1135..118W. doi:10.1196/annals.1429.006. PMID 18574216. S2CID 12016629. " ...
Despite the medical prognosis of having an estimated 18 months left to live, Stewart survived for several more years and died ... Stewart's breast cancer returned after she was imprisoned. Scheduled for surgery for other problems the week she was sentenced ... Shifrel, Scott; Fanelli, James (July 15, 2010). "Lynn Stewart, 70-year-old radical lawyer, sentenced to 10 years in prison for ... She was re-sentenced on July 15, 2010, to 10 years in prison in light of her perjury at trial. She served her sentence at the ...
Given in alternate years, with the Hunterian Oration given in the intervening years). 2016 Nigel Hunt 2014 Antony Narula 2012 ... Ellis, H. (September 1987). "The treatment of breast cancer: a study in evolution". Ann R Coll Surg Engl. 69 (5): 212-5. PMC ... Bury, J. S. (1901). "The Bradshaw Lecture on Prognosis in Relation to Disease of the Nervous System: Delivered before the Royal ... It is held on alternate years in rotation with the Hunterian Oration. 2018 Sir Leszek Borysiewicz How do we improve outcomes in ...
... gene in human breast cancer is associated with unfavorable prognosis". Carcinogenesis. 29 (5): 991-998. doi:10.1093/carcin/ ... Hu E, Zhu Y, Fredrickson T, et al. (1998). "Tissue restricted expression of two human Frzbs in preadipocytes and pancreas". ...
Yamada G, Ueno K, Nakamura S, Hanamure Y, Yasui K, Uemura M, Eizuru Y, Mansouri A, Blum M, Sugimura K (April 1997). "Nasal and ... Studies have shown that in highly metastatic ovarian, lung, breast, and other cancer cells, GSC is highly expressed early in ... "may be the most potential biomarker of drug response and poor prognosis." GRCh38: Ensembl release 89: ENSG00000133937 - Ensembl ... Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, ...
It results in chronic non-healing wounds and indicates poor prognosis, with typical life expectancy of less than one year. ... Non-uremic calciphylaxis has been observed in patients with primary hyperparathyroidism, breast cancer (treated with ... the clinical prognosis for calciphylaxis is poor. The 1-year mortality rate in patients who have end-stage kidney disease is 45 ... The median age of patients at diagnosis of calciphylaxis is 60 years and the majority of these patients are women (60-70%). The ...
... while dogs with invasive adenocarcinomas have an average survival time of one year. Tumor size also affects the prognosis, in ... Szabo S, Haislip A, Garry R (2005). "Of mice, cats, and men: is human breast cancer a zoonosis?". Microsc Res Tech. 68 (3-4): ... The average age of dogs with mammary tumors is ten to eleven years old. Obesity at one year of age and eating red meat have ... A recent study showed a better prognosis in dogs that are spayed at the time of surgery or that had been recently spayed. ...
Ren XR, Ming GL, Xie Y, Hong Y, Sun DM, Zhao ZQ, Feng Z, Wang Q, Shim S, Chen ZF, Song HJ, Mei L, Xiong WC (Nov 2004). "Focal ... They concluded that loss of 18q remains a marker for poor prognosis, and that DCC status has the potential to define a group of ... Similar results have been seen in breast cancer, acute lymphoblastic leukemia, and several others. DCC has found to be a useful ... Matsumoto Y, Irie F, Inatani M, Tessier-Lavigne M, Yamaguchi Y (April 2007). "Netrin-1/DCC signaling in commissural axon ...
"Significance of alpha 9 beta 1 and alpha v beta 6 integrin expression in breast carcinoma". Breast Cancer. 7 (1): 19-26. doi: ... Xu M, Chen X, Yin H, Yin L, Liu F, Fu Y, et al. (2015). "Cloning and characterization of the human integrin β6 gene promoter". ... High αvβ6 expression in fibrosis and cancer is usually associated with a poorer prognosis. Fibrosis occurs in response to ... Xu M, Yin L, Cai Y, Hu Q, Huang J, Ji Q, et al. (May 2018). "Epigenetic regulation of integrin β6 transcription induced by TGF- ...
ACC, generally, carries a poor prognosis, with an overall 5-year survival rate of about 50%. Five-year disease-free survival ... Feminization (estrogen excess) is most readily noted in men, and includes breast enlargement, decreased libido, and impotence. ... Wang C, Sun Y, Wu H, Zhao D, Chen J (March 2014). "Distinguishing adrenal cortical carcinomas and adenomas: a study of ... Wang C, Sun Y, Wu H, Zhao D, Chen J (March 2014). "Distinguishing adrenal cortical carcinomas and adenomas: a study of ...
In addition to results associating PLAC1 expression with risk of various cancers as well as with prognosis, the ability of ... PMID 24600606 [18] Deyssenroth MA, Li Q, Lacasaña M, Nomura Y, Marsit C, Chen J. 2017 Expression of placental regulatory genes ... and breast cancers[44-49]. In nearly all cases, PLAC1 expression is associated with poor clinical outcomes. Nowhere is this ... Chen Y, Moradin A, Schlessinger D, Nagaraja R. 2011 RXRα and LXR activate two promoters in placenta- and tumor-specific ...
... including breast cancer, after 10 years. The authors of systematic review write: "If we assume that screening reduces breast ... Digital breast tomosynthesis is associated with a higher detection of poor prognosis cancers compared to digital mammography. ... Y. Y.; Canadian Task Force on Preventive Health Care (2011). "Recommendations on screening for breast cancer in average-risk ... "Five Consecutive Years of Screening with Digital Breast Tomosynthesis: Outcomes by Screening Year and Round". Radiology. 295 (2 ...
High expression of pioneer factors is associated with poor prognosis with the exception of breast cancer where FoxA1 is ... NF-Y is a heterotrimeric complex composed of NF-YA, NF-YB, and NF-YC subunits. The key structural feature of the NF-Y/DNA ... FOXA1 particularly is expressed in 90% of breast cancer metastases and 89% of metastic prostate cancers. In the breast cancer ... In knockdown studies in the MCF-7 breast cancer cell line it was found that decreasing pioneer factors FoxA1 and AP2ɣ decreased ...
Koh, L.L; Kon, O.L; Loh, K.W; Long, Y.C; Ranford, J.D; Tan, A.L.C; Tjan, Y.Y (1998). "Complexes of salicylaldehyde ... When newborn babies are breastfed, the babies' livers and the mothers' breast milk provide sufficient quantities of copper for ... "A cuproptosis-associated long non-coding RNA signature for the prognosis and immunotherapy of lung squamous cell carcinoma". ... This multi-year research effort is expected to be finalized in 2011.[citation needed] Although a number of indicators are ...
In breast cancer, low ZXDC expression has been associated with tumor invasiveness, lymph node metastases, and poor prognosis. ... Takenawa T, Kuramitsu Y, Wang Y, Okada F, Tokuda K, Kitagawa T, et al. (January 2013). "Proteomic analysis showed down- ... Seetharam A, Bai Y, Stuart GW (April 2010). "A survey of well conserved families of C2H2 zinc-finger genes in Daphnia". BMC ... Hu J, Chen Z, Bao L, Zhou L, Hou Y, Liu L, et al. (July 2020). "Single-Cell Transcriptome Analysis Reveals Intratumoral ...
Yang J, Cao Y, Sun J, Zhang Y (2009). "Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 ... Altered expression of microRNA-16 has been observed in cancer, including malignancies of the breast, colon, brain , lung, ... 2010). "A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia". Expert Opin Ther ... Hua Z, Lv Q, Ye W, Wong CK, Cai G, Gu D, Ji Y, Zhao C, Wang J, Yang BB, Zhang Y (27 December 2006). "MiRNA-directed regulation ...
"Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma ... Zhang Y, Strehin I, Bedelbaeva K, Gourevitch D, Clark L, Leferovich J, et al. (June 2015). "Drug-induced regeneration in adult ... Cho Y, Shin JE, Ewan EE, Oh YM, Pita-Thomas W, Cavalli V (November 2015). "Activating Injury-Responsive Genes with Hypoxia ... Liu XW, Cai TY, Zhu H, Cao J, Su Y, Hu YZ, He QJ, Yang B (January 2014). "Q6, a novel hypoxia-targeted drug, regulates hypoxia- ...
Prognoses for treated localized and disseminated disease are good with long-term (e.g. up to 40 years) remissions reported for ... Primary EMZL of the breast (also termed primary MALT lymphoma of the breast) is an exceedingly rare disease. It usually ... Takeuchi Y, Miyahara K, Morito T, Okikawa Y, Kinugasa H, Moritou Y, Higashi R, Kunihiro M, Nakagawa M (January 2019). "The ... Regardless of the subtype of EMZL or its dissemination to other tissues, the prognosis for these lymphomas is good with 5 year ...
The breast cancer studies Cancer in the Augmented Breast: Diagnosis and Prognosis (1993) and Breast Cancer after Augmentation ... 10-year-mark study of the safety of the breast implants in 40,000 other women. The FDA warned the public that breast implants ... Breast Breast augmentation (Augmentation mammoplasty) Breast enlargement supplements Breast reconstruction Breast reduction ... have worse breast cancer prognosis. The use of implants for breast reconstruction after breast cancer mastectomy appears to ...
... Y (47,XYY; 48,XYYY; 48,XXYY; 49,XXYYY) occurs in 1 out of 975 males and may cause psychiatric, social, and somatic ... Overexpression of the HER2/neu gene on chromosome 17 and some type of polysomy has been reported in 8-68% of breast carcinomas ... defines a clinico-cytogenetic entity representing a subset of myeloid hematologic malignancies associated with a poor prognosis ... September 2009). "Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare ...
Implications for the Biology and Treatment of Breast Cancer Metastasis". Breast Disease. 26 (1): 87-98. doi:10.3233/bd-2007- ... Pang, Lisa Y.; Cervantes-Arias, Alejandro; Else, Rod W.; Argyle, David J. (2011-03-30). "Canine Mammary Cancer Stem Cells are ... Early diagnosis of recurrence is important and can improve the prognosis and survival of patients with cancer. Depending on the ... Pang, Lisa Y.; Hurst, Emma A.; Argyle, David J. (2016). "Cyclooxygenase-2: A Role in Cancer Stem Cell Survival and Repopulation ...
Gentles AJ, Newman AM, Liu CL, Bratman SV, Feng W, Kim D, Nair VS, Xu Y, Khuong A, Hoang CD, Diehn M, West RB, Plevritis SK, ... Their abundance varies with tumor type and stage and in some cases relates to disease prognosis. TILs can often be found in the ... The use of TILs to treat other tumor types, including lung, ovarian, bladder, and breast, are under investigation. TIL therapy ... An active immune environment within the tumor often indicates a better prognosis as can be determined by the Immunological ...
Shen Y, Ge WP, Li Y, Hirano A, Lee HY, Rohlmann A, Missler M, Tsien RW, Jan LY, Fu YH, Ptáček LJ (March 2015). "Protein mutated ... For instance, in human breast cancer (MCF7) cells, PNKD may promote tumor cell proliferation by activating the MEK/ERK ... Guo J, Dong B, Ji JF, Wu AW (October 2012). "Myofibrillogenesis regulator-1 overexpression is associated with poor prognosis of ... Gong Y, He H, Liu H, Zhang C, Zhao W, Shao RG (August 2014). "Phosphorylation of myofibrillogenesis regulator-1 activates the ...
Kwak D, Choi S, Jeong H, Jang JH, Lee Y, Jeon H, Lee MN, Noh J, Cho K, Yoo JS, Hwang D, Suh PG, Ryu SH (2012). "Osmotic stress ... RPTOR could be valuable in the prediction and prognosis of pituitary adenoma due to this correlation between protein expression ... These mutations are frequently found in a very large variety of cancers, including prostate, breast, lung, bladder, melanoma, ... Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, Hidayat S, Tokunaga C, Avruch J, Yonezawa K (Aug 2002). "Raptor, a binding ...
Seto, M., Tagawa, H., Yoshida, Y., and Kira, S. (2008). Methods for Diagnosis and Prognosis of Malignant Lymphoma. Zarbl, H., ... PROSER2 may be a biomarker of epithelial cell, breast, prostate, ovarian, lung, brain, and blood cancers as demonstrated in ... Nguyen,L.S., Kim, H.-G., Rosenfeld, J.A., Shen, Y., Gusella, J.F., Lacassie, Y., Layman, L.C., Shaffer, L.G., and Gécz, J. ( ... Nguyen, LS, Kim, HG, Rosenfeld, JA, Shen, Y, Gusella, JF, Lacassie, Y, Layman, LC, Shaffer, LG, Gécz, J (May 2013). " ...
ISBN 978-0-87893-742-4. Nakai, Y; Jeong, JW; Brown, EC; Rothermel, R; Kojima, K; Kambara, T; Shah, A; Mittal, S; Sood, S; Asano ... Studies have also found that prognosis of expressive aphasia correlates strongly with the initial severity of impairment. ... Will, A.; Akalin, Murat (2012-04-24). "Paraneoplastic Limbic Encephalitis with NMDA Receptor (NR1) Antibodies in Breast Cancer ... In most individuals with expressive aphasia, the majority of recovery is seen within the first year following a stroke or ...
... testing is performed on breast biopsy of breast cancer patients to assess prognosis and to determine suitability for ... In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer ... One year of trastuzumab therapy is recommended for all patients with HER2-positive breast cancer who are also receiving ... HER2-positive breast cancers are well established as being associated with increased disease recurrence and a poor prognosis ...
Peter reluctantly shares the prognosis with his family, Gloria's hosts. Peter tells his friend Eileen that he still loves ... In October 1981, once contacting Gloria's doctor in Lancaster, Peter learns that Gloria's breast cancer has returned after ... Dex, Robert (13 January 2018). "Discover all the nominations for this year's Evening Standard British Film Awards". London ... some years later, her death from stomach cancer. The film premiered at the Telluride Film Festival on 1 September 2017. It was ...