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*  Aldehyde oxidase 1
1993). "cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase". Proc ... "Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial ...
*  Xanthine oxidase
... can also have xanthine dehydrogenase activity (EC 1.17.1.4). Most of the protein in the liver exists in a form with xanthine ... "Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion". ... explaining why xanthine oxidase is being researched for links to cardiovascular health. Both xanthine oxidase and xanthine ... xanthine + H2O2 xanthine + H2O + O2 ⇌ {\displaystyle \rightleftharpoons } uric acid + H2O2 Xanthine oxidase can also act on ...
*  Xanthine dehydrogenase
... xanthine-NAD+ oxidoreductase, xanthine/NAD+ oxidoreductase, and xanthine oxidoreductase. Defects in xanthine dehydrogenase ... Xanthine dehydrogenase, also known as XDH, is a protein that, in humans, is encoded by the XDH gene. Xanthine dehydrogenase ... Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic ... aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MOCOS xanthine oxidase GRCh38: Ensembl release 89: ...
*  Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
Xanthine dehydrogenase (EC 1.1.1.204) catalyzes the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and ... The aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain is an evolutionary conserved protein domain. Aldehyde ... This activity is often found in a bifunctional enzyme with xanthine oxidase (EC 1.1.3.22) activity too. The enzyme can be ... Dobbek H, Gremer L, Meyer O, Huber R (August 1999). "Crystal structure and mechanism of CO dehydrogenase, a molybdo iron-sulfur ...
*  Molybdopterin
Although a tungsten-containing xanthine dehydrogenase from bacteria has been found to contain tungsten-molydopterin and also ... Schräder T, Rienhöfer A, Andreesen JR (September 1999). "Selenium-containing xanthine dehydrogenase from Eubacterium barkeri". ... carbon monoxide dehydrogenase, aldehyde oxidase. Prosthetic group of: formate dehydrogenase, purine hydroxylase, thiosulfate ... In some enzymes, such as xanthine oxidase, the metal is bound to one molybdopterin, whereas, in other enzymes, e.g., DMSO ...
*  Tungsten
Although a tungsten-containing xanthine dehydrogenase from bacteria has been found to contain tungsten-molydopterin and also ... "Selenium-containing xanthine dehydrogenase from Eubacterium barkeri". Eur. J. Biochem. 264 (3): 862-71. doi:10.1046/j.1432- ... One of the enzymes in the oxidoreductase family which sometimes employ tungsten (bacterial formate dehydrogenase H) is known to ... 1998). "Selenium-Containing Formate Dehydrogenase H from Escherichia coli: A Molybdopterin Enzyme That Catalyzes Formate ...
*  Adenine phosphoribosyltransferase
It is degraded by xanthine dehydrogenase to 2,8-dihydroxyadenine (DHA). Although DHA is protein-bound in plasma, it has poor ... It is treatable with regular doses of allopurinol or febuxostat, which inhibit xanthine dehydrogenase activity to prevent the ...
*  Oxidoreductase NAD-binding domain
Xanthine dehydrogenases, that also bind FAD/NAD, have essentially no similarity. Bacterial ferredoxin-NADP+ reductase may be ...
*  Martin Kreitman
"Sequence of the structural gene for xanthine dehydrogenase (rosy locus) in Drosophila melanogaster". Genetics. 116 (1): 67-73. ... Kreitman, M. (1983). "Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster". Nature. 304 (5925 ... subscription required) Kreitman, Martin Edward (1983). Nucleotide Sequence Variation of Alcohol dehydrogenase in Drosophila ... specifically Nucleotide Sequence Variation of Alcohol dehydrogenase in Drosophila melanogaster in 1983. The Kreitman lab does ...
*  Enzyme-thiol transhydrogenase (glutathione-disulfide)
... xanthine-dehydrogenase]:glutathione-disulfide S-oxidoreductase. Other names in common use include [xanthine-dehydrogenase]: ... xanthine oxidase] + 2 glutathione Thus, the two substrates of this enzyme are xanthine dehydrogenase and glutathione disulfide ... whereas its two products are xanthine oxidase and glutathione. This enzyme belongs to the family of oxidoreductases, ...
*  Superoxide
Xanthine oxidase - This form of the enzyme xanthine dehydrogenase produces large amounts of superoxide. IUPAC: Red Book. p. 73 ... with the enzyme xanthine oxidase. Researchers have developed a series of tool compounds termed "spin traps"(see spin trapping) ... for example xanthine oxidase. Because superoxide is toxic, nearly all organisms living in the presence of oxygen contain ...
*  Molybdenum deficiency (plant disorder)
... and Xanthine dehydrogenase, which is involved in the synthesis of uric acid from purines. Molybdenum deficiency symptoms in ...
*  Xanthinuria
Ichida K, Amaya Y, Kamatani N, Nishino T, Hosoya T, Sakai O. "Identification of two mutations in human xanthine dehydrogenase ... Type I xanthinuria can be caused by a deficiency of xanthine dehydrogenase, which is an enzyme necessary for converting ... Xanthinuria, also known as xanthine oxidase deficiency, is a rare genetic disorder causing the accumulation of xanthine. It is ... "Identification of two mutations in human xanthine dehydrogenase gene responsible for classical type I xanthinuria". J. Clin. ...
*  Abscisic-aldehyde oxidase
Sagi M, Fluhr R, Lips SH (1999). "Aldehyde oxidase and xanthine dehydrogenase in a flacca tomato mutant with deficient abscisic ...
*  Aldehyde oxidase
... and xanthine dehydrogenase, a/b hammerhead domain Gordon AH, Green DE, Subrahmanyan V (May 1940). "Liver ... AO is very similar in amino acid sequence to xanthine oxidase (XO). The active sites of AO has been found to have a ...
*  Molybdenum cofactor sulfurtransferase
"ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis ...
*  Molybdenum cofactor deficiency
Furthermore, a mutational block in molybdenum cofactor biosynthesis causes absence of enzyme activity of xanthine dehydrogenase ... xanthine, and uric acid in urine. Additionally, the disease produces characteristic MRI images that can aid in diagnosis. The ...
*  MOCOS
... sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH) and aldehyde oxidase (AOX1), which is required for ...
*  Reperfusion injury
The enzyme xanthine dehydrogenase acts in reverse, that is as a xanthine oxidase as a result of the higher availability of ... Xanthine oxidase also produces uric acid, which may act as both a prooxidant and as a scavenger of reactive species such as ...
*  Cyclic pyranopterin monophosphate
... xanthine dehydrogenase/oxidase and aldehyde oxidase. Günter Schwarz; José Angel Santamaria-Araujo; Stefan Wolf; Heon-Jin Lee; ...
*  XDH
... a mathematic assumption used in elliptic curve cryptography xanthine dehydrogenase, an enzyme. ...
*  Hyperuricemia
... and is a possible weak inhibitor of xanthine dehydrogenase. As a byproduct of its fermentation process, beer additionally ... Xanthine oxidase inhibitors decrease the production of uric acid, by interfering with xanthine oxidase. Uricosurics increase ... Yamamoto T, Moriwaki Y, Takahashi S (June 2005). "Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and ... Ethanol also increases the plasma concentrations of hypoxanthine and xanthine via the acceleration of adenine nucleotide ...
*  George B. Johnson
In POLYPLOIDY (W. Lewis, Ed.), Academic Press, N.Y. Post-translational modification of xanthine dehydrogenase in natural ... Polymorphism and predictability at the alpha-glycerophosphate dehydrogenase locus in Colias butterflies: Gradients in allele ... Hidden alleles at the alpha-glycerophosphate dehydrogenase locus in Colias butterflies, 1976, Genetics 83: 149-167 Enzyme ... 233-234 Purification and characterization of glutamic acid dehydrogenase from Escherichia coli strain K-12. Master's thesis, ...
*  Uric acid
Within cells, xanthine oxidase can exist as xanthine dehydrogenase and xanthine oxireductase, which has also been purified from ... The enzyme xanthine oxidase catalyzes formation of uric acid from xanthine and hypoxanthine, which in turn are produced from ... Allopurinol, which weakly inhibits xanthine oxidase, is an analog of hypoxanthine that is hydroxylated by xanthine ... Xanthine oxidase is a large enzyme whose active site consists of the metal molybdenum bound to sulfur and oxygen. ...
*  Selenoprotein
... nicotinate dehydrogenase of Eubacterium barkeri, or xanthine dehydrogenases). Selenium is also specifically incorporated into ...
*  IMPDH2
Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the ... IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then ... IMP dehydrogenase 2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in ... IMP dehydrogenase GRCh38: Ensembl release 89: ENSG00000178035 - Ensembl, May 2017 GRCm38: Ensembl release 89: ...