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*  PAWR
... modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1". Molecular and Cellular Biology. ... modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1". Molecular and Cellular Biology. ... The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein ... is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells. ...
*  Clear-cell sarcoma of the kidney
A Report From the National Wilms' Tumor Study Group, Journal of Clinical Oncology, Feb 1 2004, vol. 22(3), pp. 468-473, jco. ... A Review of 351 Cases From the National Wilms Tumor Study Group Pathology Center, American Journal of Surgical Pathology, Jan ... Poppe B, Forsyth R, Dhaene K, Speleman F., Soft tissue tumors: Clear cell sarcoma, Atlas Genet Cytogenet Oncol Haematol, ...
*  Large-cell lung carcinoma with rhabdoid phenotype
Beckwith JB, Palmer NF (May 1978). "Histopathology and prognosis of Wilms tumors: results from the First National Wilms' Tumor ... Colby TV, Koss MN, Travis WD (1995). "Carcinoid and other neuroendocrine tumors". In Travis WD. Tumors of Lower Respiratory ... "Wilms tumor". LCLC-RP were first recognized as a distinct entity under the 3rd (published in 1999) revision of the World Health ... aggressive tumor type. One report described a very early stage patient whose tumor recurred 6 years after initial treatment. ...
*  National Wilms Tumor Study Group
The National Wilms Tumor Study Group (NWTS) is a cancer research cooperative group in the United States formed to study a type ... Approximately 70-80% of patients with Wilms' tumor were enrolled on NWTS treatment protocols, totalling 440 patients per year. ... of kidney tumor that affects children called Wilms' tumor. In 2001, NWTS merged with several other pediatric oncology ... The NWTS was created with the purpose of improving survival of children with Wilms' tumor. NWTS studies were conducted at over ...
*  Wilms' tumor
Metastasis of tumor to lymph nodes not identified. Stage II Wilms tumor, 1 or more of the following criteria must be met: Tumor ... Stage III Wilms tumor, 1 or more of the following criteria must be met: Inoperable primary tumor. Lymph node metastasis. Tumor ... Wilms' tumor at Curlie (based on DMOZ) GeneReviews/NCBI/NIH/UW entry on Wilms Tumor Overview Information from National Cancer ... People of African descent may have slightly higher rates of Wilms tumor. The peak age of Wilms tumour is 3 to 4 years and most ...
*  PPP2R1A
"Absence of PPP2R1A mutations in Wilms tumor". Oncogene. 20 (16): 2050-2054. doi:10.1038/sj.onc.1204301. PMID 11360189. Lubert ... Walter G, Ferre F, Espiritu O, Carbone-Wiley A (1989). "Molecular cloning and sequence of cDNA encoding polyoma medium tumor ... Walter G, Ruediger R, Slaughter C, Mumby M (1990). "Association of protein phosphatase 2A with polyoma virus medium tumor ... 1994). "Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens". J. ...
*  FAM123B
It has been associated with Wilms tumor. Rivera MN, Kim WJ, Wells J, et al. (February 2007). "An X chromosome gene, WTX, is ... commonly inactivated in Wilms tumor". Science. 315 (5812): 642-645. doi:10.1126/science.1137509. PMID 17204608. ...
*  WTAP (gene)
"Entrez Gene: WTAP Wilms tumor 1 associated protein". Small TW, Bolender Z, Bueno C, et al. (2007). "Wilms' tumor 1-associating ... The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of ... 2007). "Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA". Proc. Natl. Acad ... 2007). "Wilms' tumor 1 and signal transducers and activators of transcription 3 synergistically promote cell proliferation: a ...
*  Chemotherapy regimen
Treatment of Wilms Tumor at National Cancer Institute. Last Modified: 03/29/2012 El Weshi, A; Memon, M; Raja, M; Bazarbashi, S ... in adult patients with recurrent or refractory Ewing sarcoma family of tumors". American journal of clinical oncology. 27 (5): ...
*  WT1
... Wilms tumor 1". Han Y, San-Marina S, Yang L, Khoury H, Minden MD (2007). "The zinc finger domain of Wilms' tumor 1 ... Haber DA, Buckler AJ (Feb 1992). "WT1: a novel tumor suppressor gene inactivated in Wilms' tumor". The New Biologist. 4 (2): 97 ... "The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor ... "The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor ...
*  Virtual karyotype
National Wilms Tumor Study Group (October 2005). "National Wilms Tumor Study Group. Loss of heterozygosity for chromosomes 1p ... and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group ... Tumor-specific loss-of-heterozygosity (LOH) for chromosomes 1p and 16q identifies a subset of Wilms' tumor patients who have a ... In these tumors, the INI1 gene (SMARCB1)on chromosome 22q functions as a classic tumor suppressor gene. Inactivation of INI1 ...
*  Jane M. Olson
She subsequently became involved in the National Wilms Tumor Study Group. She then worked as a research assistant in the ...
*  Amphiregulin
1999). "The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin". Cell. 98 (5): 663-73. doi:10.1016/ ... 1990). "The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity". ... "The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity". Molecular and ...
*  Metanephric dysplastic hematoma of the sacral region
Cases of primary lumbosacral Wilms tumor were described by Abrahams et al. and by Govender et al.,. It is therefore of primary ... Cancer 33:1355-1363 Tebbi K, Ragab AH, Ternberg JL, Vietti TJ (1974) An extrarenal Wilms tumor arising from a sacrococcygeal ... Pediatr Neurosurg 31:40-44 Govender D, Hadley GP, Nadvi SS, Donnellan RB (2000) Primary lumbosacral Wilms tumor with occult ... Brain Pathol 8:817-818 Ward SP, Dehner LP (1974) Sacrococcygeal teratoma with nephroblastoma (Wilms tumor). A variant of ...
*  Robert Eenhoorn
Eenhoorn's son Ryan died at age 6 of Wilms tumor in 2003; Eenhoorn and his wife Maureen have one surviving son, Ralph. On ...
*  CPVL
The deletion of this gene has been reported associated with Wilms tumor. GWAS show that genetic variations of the CPVL gene are ... "Loss of heterozygosity for the short arm of chromosome 7 in sporadic Wilms tumour". Oncogene. 17 (3): 395-400. doi:10.1038/sj. ...
*  WAGR syndrome
... (also known as WAGR complex, Wilms tumour-aniridia syndrome, aniridia-Wilms tumour syndrome) is a rare genetic ... About 50% of people develop Wilms' tumour. WAGR syndrome is caused by a mutation on chromosome 11 in the 11p13 region. ... Children with WAGR syndrome receive regular (3-4 yearly) kidney surveillance for Wilms' tumour until at least the age of 6-8 ... Specifically, several genes in this area are deleted, including the PAX6 ocular development gene and the Wilms' tumour gene ( ...
*  Beckwith-Wiedemann syndrome
In addition to Wilms tumor and hepatoblastoma, children with BWS have been shown in individual case reports to develop ... Wilms tumor, hepatoblastoma, and mesoblastic nephroma can usually be cured if diagnosed early. Early diagnosis allows ... Choyke PL, Siegel MJ, Craft AW, Green DM, DeBaun MR (March 1999). "Screening for Wilms tumor in children with Beckwith- ... particularly Wilms' tumor (nephroblastoma), pancreatoblastoma and hepatoblastoma. Individuals with BWS appear to only be at ...
*  WT1-AS
1990). "Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor". Science. 250 (4983): 991 ... "Identification of differential methylation of the WT1 antisense regulatory region and relaxation of imprinting in Wilms' tumor ... "A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' ...
*  TMEM158
2006). "Target genes of the WNT/beta-catenin pathway in Wilms tumors". Genes Chromosomes Cancer. 45 (6): 565-74. doi:10.1002/ ... 2006). "Analysis of the candidate tumor suppressor Ris-1 in primary human breast carcinomas". Mutat. Res. 594 (1-2): 78-85. doi ... Sussan TE, Pletcher MT, Murakami Y, Reeves RH (2006). "Tumor suppressor in lung cancer 1 (TSLC1) alters tumorigenic growth ... "Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence". Exp Cell Res. 273 (2 ...
*  Perlman syndrome
Diagnosis of Perlman syndrome also overlaps with other disorders associated with Wilms tumor, namely, Sotos syndrome and Weaver ... Perlman M (December 1986). "Perlman syndrome: familial renal dysplasia with Wilms tumor, fetal gigantism, and multiple ... and an increased risk for Wilms' tumor at an early age. The prognosis for Perlman syndrome is poor and it is associated with a ... and an increased risk for Wilms' tumor at an early age. The gene thought to cause some of the cases of Perlman syndrome is ...
*  Embryoma
Embryonal tumors may be benign or malignant, and include neuroblastomas and Wilms tumors. Also called embryoma. Embryomas have ... Embryonal tumor is a mass of rapidly growing cells. It is believed that it begins in embryonic (fetal) tissue. ... http://www.embryomas.net Embryonal tumor entry in the public domain NCI Dictionary of Cancer Terms This article incorporates ...
*  Simpson-Golabi-Behmel syndrome
The most common types of tumors developed in patients are the Wilms tumor and hepatoblastoma. Since the syndrome is caused by a ... There are five different types of tumors that patients with SGBS might develop, all intra-abdominal: Wilms tumor, ... Due to the high percentage of male deaths during the neonatal period, early detection of tumors is crucial. In order to detect ... SGBS in particular has been found to have a 10% tumor predisposition frequency with 94% of cases occurring in the abdominal ...
*  Frasier syndrome
"Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome--proof that a tumour-suppressor gene ... and the tumour risk phenotype is different; whilst Denys-Drash syndrome is associated with Wilms' tumour, Frasier syndrome is ... Frasier syndrome is a urogenital anomaly associated with the WT1 (Wilms tumor 1 gene) gene. It was first characterized in 1964 ... Results of various investigations identified the loss of function of WT1 to be a prerequisite of Wilms' tumour development, and ...
*  GLIPR1
"Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors". Neoplasia. 9 (11): 970-8. ... p53, the tumor suppressor gene is the most commonly mutated gene in human cancer. Mutation in p53 gene can lead to cellular ... The previous finding of RTVP1 (GLIPR1) as a p53 target gene with tumor suppressor functions prompted the researches to initiate ... Hence, GLIPR1 has been proposed to act as a tumor suppressor that undergoes epigenetic inactivation in prostate cancer. This ...
*  R-type calcium channel
2006). "Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors". Clin. Cancer ...
*  Malignant rhabdoid tumour
... (MRT) is a very aggressive form of tumour originally described as a variant of Wilms' tumour, which ... "Histopathology and prognosis of Wilms tumors: results from the First National Wilms' Tumor Study". Cancer. 41 (5): 1937-48. doi ... MRT was first described as a variant of Wilms' tumour of the kidney in 1978. MRTs are a rare and highly malignant childhood ... Weeks DA, Beckwith JB, Mierau GW, Luckey DW (1989). "Rhabdoid tumor of kidney. A report of 111 cases from the National Wilms' ...