Weibel-Palade bodies are the main source of vWF, while α-granules probably play a minor role. The small subset of Weibel-Palade ... Weibel-Palade bodies were initially described by the Swiss anatomist Ewald R. Weibel and the Romanian physiologist George Emil ... Secretory pod formation is mediated by interposition of tiny nanovesicles between bodies. As Weibel-Palade bodies fuse with ... Weibel-Palade bodies (WPBs) are the storage granules of endothelial cells, the cells that form the inner lining of the blood ...

As a result of activation, enthothelium releases Weibel-Palade bodies. Elevating shear stress induces a vascular response by ...

... is found in endothelial cells and platelets where it is stored in Weibel-Palade bodies and α-granules, respectively ... In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets P-selectin is ... is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies". J. Clin. Invest. 84 (1): 92-9. doi ...

The discovery of the Weibel-Palade bodies in 1962 was an accidental observation. Ewald Weibel was married to the violinist and ... He was one of the first scientists to describe the endothelial organelles Weibel-Palade bodies, which are named after him and ... doi:10.1007/978-3-0348-8119-7. ISBN 978-3-0348-9445-6. Weibel ER, Palade GE (October 1964). "New cytoplasmic components in ... Weibel was born in Buchs in the Aargau canton of Switzerland. After studying medicine at the University of Zurich (state ...

Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is ... human venular endothelial cells store interleukin 8 in Weibel-Palade bodies". J. Exp. Med. 188 (9): 1757-62. doi:10.1084/jem. ... "Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells". J. Exp. Med. 188 (9 ... "Immunologic profile of excessive body weight". Biomarkers. 16 (3): 243-51. doi:10.3109/1354750X.2010.547948. PMID 21506696. ...

Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is ... human venular endothelial cells store interleukin 8 in Weibel-Palade bodies". J. Exp. Med. 188 (9): 1757-62. doi:10.1084/jem. ... "Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells". J. Exp. Med. 188 (9 ... it has since been found that interleukins are produced by a wide variety of body cells. The term was coined by Dr Vern Paetkau ...

"Structural organization of Weibel-Palade bodies revealed by cryo-EM of vitrified endothelial cells". Proceedings of the ...

3-fucosyltransferase VI in Weibel-Palade bodies of human endothelial cells". Proc. Natl. Acad. Sci. U.S.A. 97 (15): 8369-74. ...

"Aftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cells". Mol. ...

... including pinocytotic vesicles and Weibel-Palade bodies. Stomach. Section of the human esophagus. Moderately magnified. ... "Morphologic study of small intestinal submucosa as a body wall repair device". J. Surg. Res. 103 (2): 190-202. doi:10.1006/jsre ...

VWF is also stored in the Weibel-Palade bodies of the endothelial cells and secreted constitutively into the blood. Platelets ... being the central body; and the spread, a cooked fried egg with a denser central body. These changes are all brought about by ... List of distinct cell types in the adult human body Laki K (December 1972). "Our ancient heritage in blood clotting and some of ... Many factors affect the increment including the recipient's body size, the number of platelets transfused, and clinical ...

P-selectin release from Weibel-Palade bodies, on blood vessel endothelial cells, can be induced by a number of factors. One ...

... -2 is produced and stored in Weibel-Palade bodies in endothelial cells and acts as a TEK tyrosine kinase antagonist ...

These cytokines induce the externalisation of Weibel-Palade bodies in endothelial cells, presenting pre-formed P-selectins on ... is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies". The Journal of Clinical ... Leukocytes use the blood as a transport medium to reach the tissues of the body. Here is a brief summary of each of the four ... allowing in some cases for cells to migrate to specific sites within the body (e.g. the skin). At the same time, chemokines ...

VWFs coming out of the Golgi are packaged into storage organelles, Weibel-Palade bodies (WPBs) in endothelial cells and α- ... in the Weibel-Palade bodies), megakaryocytes (α-granules of platelets), and subendothelial connective tissue. The basic VWF ...

Desmopressin stimulates the release of VWF from the Weibel-Palade bodies of endothelial cells, thereby increasing the levels of ...

He focused on Weibel-Palade bodies (a storage organelle unique to the endothelium, containing von Willebrand factor and various ... Weibel, ER; Palade, GE (1964). "New cytoplasmic components in arterial endothelia". The Journal of Cell Biology. 23 (1): 101- ... Palade received his M.D. in 1940 from the Carol Davila School of Medicine in Bucharest. Palade was a member of the faculty at ... "The Palade Symposium: Celebrating Cell Biology at Its Best". Molbiolcell.org. Retrieved on 2016-06-10. "Prof. George Palade: ...

... nissl bodies MeSH A11.284.430.214.190.500.950 - weibel-palade bodies MeSH A11.284.430.214.190.750 - cytoskeleton MeSH A11.284. ... weibel-palade bodies MeSH A11.284.430.214.190.875.190.250 - endosomes MeSH A11.284.430.214.190.875.190.550 - lysosomes MeSH ... heinz bodies MeSH A11.284.420.390 - inclusion bodies, viral MeSH A11.284.420.400 - intranuclear inclusion bodies MeSH A11.284. ... 420.460 - lewy bodies MeSH A11.284.430.106 - cell nucleus MeSH A11.284.430.106.279 - cell nucleus structures MeSH A11.284. ...

Weibel-Palade body Angiocrine growth factors Endothelial Cell Tropism List of distinct cell types in the adult human body " ... An impaired function can lead to serious health issues throughout the body. The endothelium is a thin layer of single flat ( ...

P-selectin, the largest selectin, is stored in α-granules of platelets and in Weibel-Palade bodies of endothelial cells, and is ... histamine and thrombin cause endothelial cells to mobilize immediate release of preformed P-selectin from Weible-Palade bodies ...

Japanese men's magazine Weibel-Palade body, storage granules of endothelial cells West Palm Beach, Florida, United States, a ...

Swiss biologist eponymy Weibel Scientific - a Danish designer and manufacturer of doppler radars Weibel-Palade body - storage ... Weibel may refer to: office of "usher" in Switzerland, see Huissier a surname Charles Weibel (born 1950) - American ... mathematician Weibel (sport shooter) - Swiss Olympic sports shooter Peter Weibel (1944-2023) - Austrian artist Ewald Weibel - ... that form the inner lining of the blood vessels and heart Weibel Elementary School Weibel M/1932 - a light machine gun concept ...

... which is stored in vesicles called Weibel-Palade bodies, E-selectin is not stored in the cell and has to be transcribed, ...

German anatomist Weibel-Palade body - Ewald R. Weibel (1929-2019), Swiss biologist, and George Emil Palade (1912-2008), ... Austrian physician Herring bodies - Percy Theodore Herring (1872-1967), English physiologist Heschl's gyri - Richard L. Heschl ... Johannes Peter Müller Nissl bodies or granules and Nissl substance - Franz Nissl Sphincter of Oddi - Ruggero Oddi Pacinian ... German-American physiologist Balbiani bodies - Édouard-Gérard Balbiani Bartholin's gland - Caspar Bartholin the Younger (1655- ...