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*  Management of atrial fibrillation
"Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: ... and is not an alternative for patients who are judged to be at high risk of bleeding on warfarin therapy. Warfarin treatment ... the combination of aspirin and the lower dose of warfarin was significantly inferior to the standard adjusted-dose warfarin ( ... a study comparing the initiation of warfarin alone with warfarin and low molecular weight heparin shows no significant ...
*  Arterial embolism
In case of high risk for developing thromboembolism, antithrombotic medication such as warfarin or coumadin may be taken ... Examples are: Anticoagulants (such as warfarin or heparin) and antiplatelet medication (such as aspirin, ticlopidine, and ...
*  Vitamin K2
Patients on warfarin (Coumadin) treatment, or treatment with other vitamin K antagonist drugs, are therefore advised not to ... Price, P. A.; Faus, S. A.; Williamson, M. K. (1998). "Warfarin causes rapid calcification of the elastic lamellae in rat ... Vascular calcification was shown to appear in warfarin-treated experimental animals within two weeks. Also in humans on OAC ... Bone mineral density was significantly lower in stroke patients with long-term warfarin treatment compared to untreated ...
*  VKORC1
As the pharmacological target of warfarin, VKORC1 is considered a candidate gene for the variability in warfarin response. ... Warfarin causes inhibition on VKORC1 activities and leads to a reduced amount of vitamin K available to serve as a cofactor for ... Lower warfarin doses are needed to inhibit VKORC1 and to produce an anticoagulant effect in carriers of the A allele. Genetic ... Warfarin is a commonly prescribed oral anticoagulant, or blood thinner used to treat blood clots such as deep vein thrombosis ...
*  Warfarin necrosis
... such as warfarin). Warfarin necrosis is a rare but severe complication of treatment with warfarin or related anticoagulants. ... Warfarin necrosis is also different from another drug eruption associated with warfarin, purple toe syndrome, which usually ... Zauber NP, Stark MW (May 1986). "Successful warfarin anticoagulation despite protein C deficiency and a history of warfarin ... so these drugs can also be used to prevent clotting during the first few days of warfarin therapy and thus prevent warfarin ...
*  Diphenadione
... longer than warfarin and other synthetic indandione anticoagulants.[better source needed] It is toxic to mammals, in all forms ... warfarin). For purposes of treating toxicity on exposure, diphenadione is grouped with other vitamin K antagonists (coumarins ...
*  Mixing study
K-dependent and a few nonvitamin K-dependent factors to be sure that the problem is not accidental or surreptitious warfarin ...
*  Warfarin
... major being 7-OH warfarin formed from S-warfarin by CYP2C9 and 10-OH warfarin from R-warfarin by CYP3A4. Warfarin is slower ... Drug Information Portal-Warfarin Warfarin bound to proteins in the PDB: R-warfarin, S-warfarin CDC - NIOSH Pocket Guide to ... S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response. Both the enantiomers of warfarin ... Warfarin was first registered for use as a rodenticide in the US in 1948, and was immediately popular. Although warfarin was ...
*  Warfarin resistance
In incomplete warfarin resistance, people only respond to high doses of warfarin; in complete warfarin resistance, the drug has ... Warfarin resistance is a rare condition in which people have varying degrees of tolerance to the anticoagulant drug warfarin. ... One gene that has been identified in warfarin resistance is VKORC1, a gene responsible for warfarin metabolism. It is inherited ... This can be because the drug is metabolized quickly or because the clotting cascade does not interact with warfarin as it ...
*  Fetal warfarin syndrome
... (dysmorphism due to warfarin, warfarin embryopathy) is a condition associated with administration of ... Datagenno - Fetal Warfarin Syndrome Raghav S, Reutens D (February 2007). "Neurological sequelae of intrauterine warfarin ... Hou JW (September 2004). "Fetal warfarin syndrome" (PDF). Chang Gung Med J. 27 (9): 691-5. PMID 15605910. Archived (PDF) from ... warfarin during pregnancy. Associated conditions include hypoplasia of nasal bridge, laryngomalacia, pectus carinatum, ...
*  Vitamin-K-epoxide reductase (warfarin-sensitive)
At least one compound, Warfarin is known to inhibit this enzyme. Lee JJ, Fasco MJ (1984). "Metabolism of vitamin K and vitamin ... In enzymology, a vitamin-K-epoxide reductase (warfarin-sensitive) (EC 1.17.4.4) is an enzyme that catalyzes the chemical ...
*  Vitamin-K-epoxide reductase (warfarin-insensitive)
In enzymology, a vitamin-K-epoxide reductase (warfarin-insensitive) (EC 1.17.4.5) is an enzyme that catalyzes the chemical ...
*  DMOZ - Health: Pharmacy: Drugs and Medications: W: Warfarin
All sites related to the drug Warfarin - an anticoagulant. ... "Health ... Warfarin" search on: AOL - Ask - Bing - DuckDuckGo ... A free-to-use web interface that will simulate the action of oral anticoagulants such as warfarin and acenocoumarol based on ... helpful links and services are available for patients and healthcare professionals for warfarin sodium. ...
*  Dabigatran
It is used as an alternative to warfarin, since it does not have to be monitored by blood tests, but offers similar results in ... unlike for warfarin, The dabigatran antidote idarucizumab was approved by the FDA in 2015. Pradaxa received a Notice of ... In May 2014 the FDA reported the results of a large study comparing dabigatran to warfarin in 134,000 Medicare patients. The ... It appears to be as effective as warfarin in preventing nonhemorrhagic strokes and embolic events in those with atrial ...
*  List of OMIM disorder codes
RAB3GAP1 Warfarin resistance; 122700; VKORC1 Warfarin sensitivity; 122700; CYP2C9 Warsaw breakage syndrome; 613398; DDX11 ...
*  DPT vaccine
"The difference between Tdap and DTaP; dabigatran versus warfarin". JAAPA. Retrieved 2014-06-25. "DTaP-Tdap mix-ups now ...
*  List of drugs: Cm-Co
Redirects to Warfarin. coumafos (INN) coumamycin (INN) coumazoline (INN) coumetarol (INN) Covan Covera-HS Coversyl covirasil ( ...
*  Hypercoagulability in pregnancy
Warfarin, heparin and LMWH do not seem to pass into breast milk, so these are not contraindicated in breastfeeding. Valvular ... Whether warfarin can be reinitiated after the 12th week of pregnancy is unclear. In a recent retrospective analysis, resumption ... Warfarin and other vitamin K-inhibiting agents are contraindicated during the first trimester of pregnancy because of the ... Still, there seems to be no teratogenic effect of warfarin before six weeks of gestation. However, unfractionated heparin and ...
*  Boxed warning
"Black Box for Warfarin". Retrieved 2007-08-15. Associated Press (February 10, 2006). "Strongest warning suggested for ADHD ... the FDA added a boxed warning to the anticoagulant warfarin due to the risk of bleeding to death. In February 2006, the FDA's ...
*  Necrosis
Nazarian RM, Van Cott EM, Zembowicz A, Duncan LM (2009). "Warfarin-induced skin necrosis". J. Am. Acad. Dermatol. 61 (2): 325- ...
*  Prothrombin complex concentrate
It may also be used in those with not enough of these factors due to other reasons such as warfarin therapy. It is given by ... Baker, R. I.; Coughlin, P. B.; Gallus, A. S.; Harper, P. L.; Salem, H. H.; Wood, E. M.; Warfarin Reversal Consensus, G. (2004 ... PCC reverses the effects of warfarin and other vitamin K antagonist anti-coagulants and is used in cases of significant ... "Kcentra, from CSL Behring, Receives FDA Approval for Use in Warfarin Reversal in Patients Undergoing Surgery". CSL Behring. 13 ...
*  Dicloxacillin
Lacey, CS (May 2004). "Interaction of dicloxacillin with warfarin". The Annals of pharmacotherapy. 38 (5): 898. doi:10.1345/aph ... Dicloxacillin has potential interactions with following drugs: Warfarin Methotrexate Tetracyclines Despite dicloxacillin being ...
*  Discovery and development of direct Xa inhibitors
He and his colleagues worked on several variations and ended up with a substance they named warfarin in 1948. It wasn't until ... Direct Xa inhibitors are just as efficacious as LMWH and warfarin but they are given orally and don't need as strict monitoring ... Warfarin treatment requires blood monitoring and dose adjustments regularly due to its narrow therapeutic window. If ... 2008). "Warfarin: An Historical Perspective". Hematology, The Education Program. 2008: 251. doi:10.1182/asheducation-2008.1.251 ...
*  4-Hydroxycoumarins
See warfarin for this history. The synthetic drugs in the 4-hydroxycoumarin class are all noted primarily for their use as ... The simplest synthetic molecule in the 4-hydroxycoumarin class is warfarin, in which the aromatic 3-position substituent is a ... Coumadin is a brandname for warfarin). They are also referred to as "coumarins," in reference to their derivation, although ... were developed as rodenticides for rodents that have developed warfarin resistance. The second generation agents have even ...
*  Antiphospholipid syndrome
In pregnancy, low molecular weight heparin and low-dose aspirin are used instead of warfarin because of warfarin's ... Warfarin/Coumadin is not used during pregnancy because it can cross the placenta, unlike heparin, and is teratogenic. The ... The goal of the prophylactic treatment with warfarin is to maintain the patient's INR between 2.0 and 3.0. It is not usually ... Often, this disease is treated by giving aspirin to inhibit platelet activation, and/or warfarin as an anticoagulant. ...