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*  Negative-sense single-stranded RNA virus
After assembly and maturation of nucleocapsid, the new virions exit the cell by budding or lysing through cell membrane to ... parainfluenza viruses, influenza viruses, Ebola virus, Marburg virus are included within the NSV. The life cycle of NSV has a ... includes Measles virus, Mumps virus, Nipah virus, Hendra virus, and NDV Family Pneumoviridae - includes RSV and Metapneumovirus ... Viruses of the family Tenuivirus only infect plants. A few viruses known to infect humans include Marburg virus, Ebola, measles ...
*  Discovery and development of NS5A inhibitors
This may cause abnormal assembly leading to malformed viruses. Some studies have revealed that inhibition of the viral assembly ... "Kinetic Analyses Reveal Potent and Early Blockade of Hepatitis C Virus Assembly by NS5A Inhibitors". Gastroenterology. 147 (2 ... "Involvement of Hepatitis C Virus NS5A Hyperphosphorylation Mediated by Casein Kinase I- in Infectious Virus Production". ... The virus has been around for over a millennia and has been classified into six known genotypes, each of which contains ...
*  Vesiculovirus matrix proteins
These proteins play a major role in assembly and budding of VSIV virions. Their main role is to aid virus assembly. They starts ... Enveloped viruses acquire their membrane by budding at a membrane of their host cell. The structure of these matrix proteins ... The matrix (M) protein of the virus causes many of the cytopathic effects of VSV, including an inhibition of host gene ... Kopecky SA, Lyles DS (May 2003). "The cell-rounding activity of the vesicular stomatitis virus matrix protein is due to the ...
*  NS2 (HCV)
... "trans-Complementation of an NS2 Defect in a Late Step in Hepatitis C Virus (HCV) Particle Assembly and Maturation". PLoS Pathog ... Nonstructural protein 2 (NS2) is a viral protein found in the hepatitis C virus. It is also produced by influenza viruses, and ... Lorenz, Ivo (Aug 2010). "The Hepatitis C Virus Nonstructural Protein 2 (NS2): An Up-and-Coming Antiviral Drug Target". Viruses ... "Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly". J Biol Chem ...
*  N-myristoyltransferase 1
1990). "Myristoylation of gag proteins of HIV-1 plays an important role in virus assembly". AIDS Res. Hum. Retroviruses. 6 (6 ... Bryant M, Ratner L (1990). "Myristoylation-dependent replication and assembly of human immunodeficiency virus 1". Proc. Natl. ... Lee PP, Linial ML (1994). "Efficient particle formation can occur if the matrix domain of human immunodeficiency virus type 1 ... Tashiro A, Shoji S, Kubota Y (1990). "Antimyristoylation of the gag proteins in the human immunodeficiency virus-infected cells ...
*  Megalocytivirus
A headful mechanism is utilized to package the concatameric viral DNA into virions formed at cytoplasmic virus assembly sites. ... Megalocytivirus is one of five genera of viruses within the family Iridoviridae and one of three genera within this family ... Infection with these viruses produces a characteristic presence of enlarged basophilic cells within infected organs. ... In Fauquet CM, Mayo MA, Maniloff J, Desselburger U, Ball LA (eds). Virus Taxonomy, Eighth report of the International Committee ...
*  Ebola viral protein 24
"Biochemical and functional characterization of the Ebola virus VP24 protein: Implications for a role in virus assembly and ... The history of Ebola virus characterization is rather short as most research on the mechanisms employed by the virus have ... eVP24 provides Ebola with an advantages over other viruses which disrupt STAT1 because unlike most other viruses, eVP24 uses ... 2014). "Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of ...
*  Enterobacteria phage P22
The viral capsid has been the subject of studies in P22 virus assembly. Like other large dsDNA viruses, P22 first builds a ... The action scaffolding protein in procapsid assembly is common in other large icosahedral viruses including the herpes viruses ... Like many phage viruses, it has been used in molecular biology to induce mutations in cultured bacteria and to introduce ... Olia AS, Al-Bassam J, Winn-Stapley DA, Joss L, Casjens SR, Cingolani G (2006). "Binding-induced stabilization and assembly of ...
*  Hepatitis E
"Structure of the hepatitis E virus-like particle suggests mechanisms for virus assembly and receptor binding". Proceedings of ... A new virus designated rat hepatitis E virus has been isolated. A rabbit hepatitis E virus has been described, with a study ... caused by infection with a virus called hepatitis E virus. It is one of five known human hepatitis viruses: A, B, C, D, and E. ... Recovery leads to virus clearance from the blood, while the virus may persist in stool for much longer. Recovery is also marked ...
*  Viral matrix protein
Structural proteins linking the viral envelope with the virus core. They play a crucial role in virus assembly, and interact ... This assembly complex will now bud out of the cell as new mature viruses. Viral matrix proteins, like many other viral proteins ... An example is the M1 protein of the influenza virus, showing affinity to the glycoproteins inserted in the host cell membrane ... They are found in many enveloped viruses including paramyxoviruses, orthomyxoviruses, herpesviruses, retroviruses, filoviruses ...
*  Carrot Yellow-leaf Virus
However, minor capsid protein is not essential for assembly nor genome protection. A virus with a mutated minor capsid protein ... This virus is non-enveloped, being a member of the closteroviridae virus family. Carrot yellow-leaf virus is a variant of beet ... The major capsid protein is essential for virus assembly; mutations in the gene responsible for encoding it result in ... The virus genome is 1250-2200 nm in length and 10-13 nm in diameter. In order to replicate, the carrot yellow leaf virus ...
*  Gammaretrovirus core encapsidation signal
... signal is an RNA element known to be essential for stable dimerisation and efficient genome packaging during virus assembly. ... D'Souza V, Summers MF (2004). "Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus". Nature. ... "NMR structure of the 101-nucleotide core encapsidation signal of the Moloney murine leukemia virus". J Mol Biol. 337 (2): 427- ...
*  Cache Valley virus
Once the virus has replicated enough, it is encapsidated. Assembly and budding of the newly synthesized virions occurs at the ... a teratogenic virus of the Orthobunyavirus genus closely related to Cache Valley Virus, the virus was shown to replicate in the ... Therefore, deer tend to act as amplifying hosts to the virus. While the virus is able to replicate in adult animals, besides a ... Role of the Cytoplasmic Tail Domains of Bunyamwera Orthobunyavirus Glycoproteins Gn and Gc in Virus Assembly and Morphogenesis ...
*  Nodamura virus
Virus assembly in the cytoplasm around genomic RNA1 and RNA2. Assembled capsid protein alpha is cleaved into capsid protein ... Nodamura virus is a +ssRNA virus. It is a member of the virus family nodaviridae. The virus family nodaviridae is made up of ... Other viruses in this genus are flock house virus and black beetle virus. The structure of nodamura virus is consistent with ... Replication of Nodamura virus, a +ssRNA virus, occurs in the cytoplasm of cells. Once the virus has entered the host cell, the ...
*  Lipid raft
Chazal, Nathalie; Gerlier, Denis (2003). "Virus Entry, Assembly, Budding, and Membrane Rafts". Microbiology and Molecular ... Human T-lymphotropic virus Type I (HTLV-1) enters cell via glucose transporter 1 (GLUT-1); Ebola virus and Marburg virus uses ... Semliki Forest virus (SFV) and Sindbis virus (SIN) require cholesterol and sphingolipids in target membrane lipid rafts for ... Human Immunodeficiency virus (HIV), as a sexually-transmitted animal virus, must first penetrate a barrier of epithelial cells ...
*  2,3-Bis(acetylmercaptomethyl)quinoxaline
It does not interfere with attachment, penetration or DNA synthesis, but interrupts a late stage in virus assembly and/or ...
*  Papillomaviridae
Twarock, R. (2004). "A tiling approach to virus capsid assembly explaining a structural puzzle in virology". Journal of ... Interactions between L1 and sulfated sugars on the cell surface promote initial attachment of the virus. The virus is then able ... Like most non-enveloped viruses, the capsid is geometrically regular and presents icosahedral symmetry. Self-assembled virus- ... Though many viruses present 72 capsomers, papillomaviridae are almost unique in that all of their capsomers are made of ...
*  Influenzavirus C
Ali A, Avalos RT, Ponimaskin E, Nayak DP (2000). "Influenza virus assembly: effect of influenza virus glycoproteins on the ... Influenza virus C is a genus in the virus family Orthomyxoviridae, which includes the viruses that cause influenza. The species ... Influenza viruses, like all viruses in the Orthomyxoviridae family, are enveloped RNA viruses with single stranded genomes. The ... The M1 protein is required for virus assembly and NP functions in transcription and replication. These viruses also contain ...
*  HHV capsid portal protein
Newcomb WW, Thomsen DR, Homa FL, Brown JC (September 2003). "Assembly of the herpes simplex virus capsid: identification of ... When a virus infects a cell, it is necessary for the viral DNA to be released from the capsid. The Herpes virus DNA exits ... "Involvement of the portal at an early step in herpes simplex virus capsid assembly". Journal of Virology. 79 (16): 10540-6. doi ... Assembly of portal units is an initial step in constructing capsids of viral progeny. Capsids assembled in the absence of ...
*  Capsid
"Involvement of the Portal at an Early Step in Herpes Simplex Virus Capsid Assembly". Journal of Virology. 79 (16): 10540-6. doi ... The most understood helical virus is the tobacco mosaic virus. The virus is a single molecule of (+) strand RNA. Each coat ... The majority of viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have ... The size is also different the tobacco mosaic virus has a 16.33 protein subunits per helical turn, while the influenza A virus ...
*  Nodaviridae
... at a conserved Asn/Ala site during virus assembly. Viral replication is cytoplasmic. Entry into the host cell is achieved by ... Black beetle virus Boolarra virus Flock House virus Nodamura virus Pariacoto virus Genus: Betanodavirus Barfin flounder nervous ... virus Redspotted grouper nervous necrosis virus Striped jack nervous necrosis virus Tiger puffer nervous necrosis virus While ... "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015. International Committee on Taxonomy of Viruses University of Leicester ...
*  M1 protein
... and a role in the virus assembly and budding. The protein was found to undergo phosphorylation in the host cell. The M1 protein ... The M1 protein is a matrix protein of the influenza virus. It forms a coat inside the viral envelope. This is a bifunctional ... H5N1 genetic structure Sha B, Luo M (March 1997). "Structure of a bifunctional membrane-RNA binding protein, influenza virus ... "Combined results from solution studies on intact influenza virus M1 protein and from a new crystal form of its N-terminal ...
*  Yizhi Jane Tao
Structure of the hepatitis E virus-like particle suggests mechanisms for virus assembly and receptor binding in Proceedings of ... Professor Tao led a team of researchers to be the first to map the structure of the influenza A virus nucleoprotein to an ... "Scientists Find Potential 'Achilles' Heel' in Bird-Flu Virus". The Washington Post. 2006-12-06. "Biochemist among most ... ". "The Stephen C. Harrison Laboratory of Structural Cell Biology - Alumni". The mechanism by which influenza A virus ...
*  VP40
The virus matrix protein VP40 is a major structural protein that plays a central role in virus assembly and budding at the ... Most commonly it is found in the Ebola virus (EBOV), a type of non-segmented, negative-strand RNA virus. Ebola virus causes a ... Silva LP, Vanzile M, Bavari S, Aman JM, Schriemer DC (2012). "Assembly of Ebola Virus Matrix Protein VP40 Is Regulated by Latch ... Study of the matrix protein VP40 is important due to the high mortality rate of the Ebola virus, which is listed as a WHO Risk ...
*  Hussein Naim
... basis of enveloped viruses assembly, and (ii) the mechanisms of membrane protein sorting and endocytosis in polarized ... Measles virus matrix protein specifies apical virus release and glycoprotein sorting in epithelial cells. EMBO J. 19, 3576-3585 ... Basis for selective incorporation of glycoproteins into influenza virus envelope. J. Virol. 67, 4831-4841 Measles Viruses with ... Oncolytic measles virus in cutaneous T-cell lymphomas mount anti-tumor immune responses in vivo and target interferon resistant ...
*  Camelpox
When all of the structural proteins have been produced, viral assembly takes place. The newly formed virus particles can be ... The Orthopox virus that causes Camelpox behaves very similarly to the virus that causes Smallpox. After the virus attaches to a ... The Camelpox Virus (CMPV) that causes Camelpox is an Orthopoxvirus that is very closely related to the Variola virus that ... "Orthopoxvirus". Virus Zone. Swiss Institute of Bioinformatics. Pfeffer, M (Jan 1998). "Fatal Form of Camelpox Virus Infection ...
*  Clinton Haines
He wrote his first computer virus in assembly language using the A86 assembler in the early 1990s. Haines was responsible for ... A computer virus was written in his honour (RIP Terminator-Z by VLAD). The virus, named 'Memorial', pays acknowledgement to ... The Dudley virus was a variant of the No Frills code with the text [Oi Dudley!][PuKE]. Haines died from a heroin overdose in ... His virus Dudley also infected the computers of Telstra (then called Telecom Australia), shutting down their system in two ...