Loading...
*  Hepatitis B virus precore mutant
The C gene has a precore and a core region. If translation is initiated at the precore region, the protein product is HBeAg. If ... The precore region is not necessary for viral replication. Precore mutants can replicate. They are readily detectable by HBV ... Basal core promoter mutants cause a reduction in HBeAg production. These mutations, A1762T and G1764A, occur in the basal core ... The HBV has four genes: S, P, C, and X. The S gene codes for the "major" envelope protein (HBsAg). The largest gene is P. It ...
*  Orthomyxoviridae
The vRNA and viral core proteins leave the nucleus and enter this membrane protrusion (step 6). The mature virus buds off from ... which encode 11 proteins (HA, NA, NP, M1, M2, NS1, NEP, PA, PB1, PB1-F2, PB2). The best-characterised of these viral proteins ... or transported back into the nucleus to bind vRNA and form new viral genome particles (step 5a). Other viral proteins have ... part of the haemagglutinin protein fuses the viral envelope with the vacuole's membrane, releasing the viral RNA (vRNA) ...
*  SRPK2
... of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein ... "Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein". J. ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038/ ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038/ ...
*  Influenza
... which causes the core to disassemble and release the viral RNA and core proteins. The viral RNA (vRNA) molecules, accessory ... wrapped around a central core. The central core contains the viral RNA genome and other viral proteins that package and protect ... The vRNA and viral core proteins leave the nucleus and enter this membrane protrusion (step 6). The mature virus buds off from ... or transported back into the nucleus to bind vRNA and form new viral genome particles (step 5a). Other viral proteins have ...
*  Feline foamy virus
The foamy virus protease cuts the Gag protein and thus activates the viral core disassembly at the organizing center. Viral ... Once inside the host cell, the viral core makes its way along the microtubules to its destination; the microtubule-organizing ... mRNAs and proteins are produced and the virions or complete viral particles gather in the cytoplasm of the cell. A retrieval ... The FeFV viral genome is linear with (+) single stranded RNA or double stranded DNA depending on the timing of reverse ...
*  Coxsackie B4 virus
... and 3A are core viral proteins. The genome also codes for 4 capsid proteins, VP4, VP1, VP2, and VP3 that form an icosahedral ... Once viral genome and viral proteins reach high enough concentrations within the host cell, structural proteins must assemble. ... UTR is the viral protein VPg which aids in viral entry and replication. 2A and 3C are viral proteinases which aid in the ... As soon as viral proteins have been translated and cleaved, negative sense transcripts of the viral genome are made to serve as ...
*  Feline immunodeficiency virus
The capsid protein derived from the polyprotein Gag is assembled into a viral core (the protein shell of a virus) and the ... This interaction causes the viral and cellular membranes to fuse, allowing the transfer of the viral RNA into the cytoplasm, ... The viral envelope also has surface projections that are small, 8 nm, and evenly cover the surface. The FIV virus genome is ... The bovine protein is homologous with other mammalian species and is a homogeneous 50 kDa glycoprotein with an isoelectric ...
*  Endogenous retrovirus
These three genes are gag (encodes for structural proteins for the viral core), pol(encodes for reverse transcriptase, ... making the separate proteins functional. Reverse transcriptase functions to synthesize viral DNA from the viral RNA in the host ... integrase, and protease), and env (encodes for coat proteins for the virus's exterior). These viral proteins are encoded as ... protein-coding regions of the viral genome. The general retrovirus genome consists of three genes vital for the invasion, ...
*  Sheeppox
Then, SPV fuses with the plasma membrane which releases the viral core into the cytoplasm. Viral proteins help contribute to ... After early expression, the viral genome becomes free in the cytoplasm due to the core no longer being coated with the capsid. ... The virus enters the host cell via endocytosis which is initiated by the attachment of viral proteins to host ... Young, lactating, and older animals are more susceptible to this viral infection though no viral preference has been found. ...
*  Viral matrix protein
Structural proteins linking the viral envelope with the virus core. They play a crucial role in virus assembly, and interact ... Viral matrix proteins, like many other viral proteins, can exert different functions during the course of the infection. For ... In herpesviruses, the viral matrix is usually called viral tegument and contains many proteins involved in viral entry, early ... An example is the M1 protein of the influenza virus, showing affinity to the glycoproteins inserted in the host cell membrane ...
*  Camelpox
... the viral core dissolves, and the genetic material is bare within the cytoplasm. When all of the structural proteins have been ... The DNA is encased in the viral core. Two lateral bodies are found outside the viral core, and are believed to hold the enzymes ... After the virus attaches to a host cell, it injects its viral core (the shell containing its DNA) into the cell's cytoplasm. ... The most common medication used to treat Camelpox is Cidofovir, a broad spectrum anti-viral that acts by inhibiting the viral ...
*  Signal peptide peptidase
... also known as core protein) of the Hepatitis C virus and thus influences viral reproduction rate. In mice, a nonamer peptide ... processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral ... In molecular biology, the Signal Peptide Peptidase (SPP) is a type of protein that specifically cleaves parts of other proteins ... by the action of signal peptidase and also plays key roles in immune surveillance and the maturation of certain viral proteins ...
*  HBcAg
... (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person ... The presence of both HBcAg and HBeAg proteins together act as a marker of viral replication, and antibodies to these antigens ... May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg ... HBcAg is an antigen that can be found on the surface of the nucleocapsid core (the inner most layer of the hepatitis B virus). ...
*  Clusterin
The chaperone protein then aids hepatitis C viral assembly by stabilizing its core and NS5A units. CLU expression in the kidney ... CLU is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, ... which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP- ... CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been ...
*  Mammalian orthoreovirus
... which is enclosed in a 70-80 nm double layered protein capsid, made up of an inner (T=2) and outer layer (T=13). The viral core ... Mammalian orthoreovirus' viral proteins and its genomic RNAs aggregate in cytoplasm viral factories. The positive and negative ... The inner capsid proteins require the co-expression of the T2 protein and the σ2 protein, to stabilize the inner capsid ... viral core. This process occurs in this manner so the viral double stranded RNA is not exposed to the cytoplasm, as this would ...
*  Mastadenovirus
Import of the viral genome into host nucleus mediated by core protein VII. Transcription of early genes (E genes) by host RNA ... Microtubular transport toward nucleus of the viral genome still protected by the core protein VII and a partial capsid mainly ... The genome codes for 40 proteins. Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral ... Host translation shutoff performed by the viral 100K protein. Assembly of new virions in the nucleus. Virions are released by ...
*  Rotaviral gastroenteritis
This causes the breakdown of VP7 trimers into single protein subunits, leaving the VP2 and VP6 protein coats around the viral ... By remaining in the core, the viral RNA evades innate host immune responses called RNA interference that are triggered by the ... and consists of viral factories thought to be made by two viral nonstructural proteins: NSP5 and NSP2. Inhibition of NSP5 by ... of the two protein shells and the viral RNA-dependent RNA polymerasecreates mRNA transcripts of the double-stranded viral ...
*  List of MeSH codes (D12.776)
... capsid proteins MeSH D12.776.964.970.600.850 - viral core proteins MeSH D12.776.964.970.600.850.350 - gene products, gag MeSH ... fusion proteins, gag-pol MeSH D12.776.964.775.350.400 - hiv core protein p24 MeSH D12.776.964.775.375.325 - fusion proteins, ... hn protein MeSH D12.776.964.970.880.910 - viral fusion proteins MeSH D12.776.964.970.880.910.330 - hiv envelope protein gp41 ... groel protein MeSH D12.776.602.500.500.100 - fusion proteins, bcr-abl MeSH D12.776.602.500.500.320 - fusion proteins, gag-onc ...
*  Hepatitis B
... enclosing viral genome. The icosahedral core particle is made of 180 or 240 copies of the core protein, alternatively known as ... is used to make the new copies of the genome and to make the capsid core protein and the viral DNA polymerase. These four viral ... There are four known genes encoded by the genome, called C, X, P, and S. The core protein is coded for by gene C (HBcAg), and ... HBeAg is produced by proteolytic processing of the pre-core protein. In some rare strains of the virus known as Hepatitis B ...
*  Orthopoxvirus
Fusion of the viral envelope with the plasma membrane releases the viral core into the host cytoplasm. Expression of early- ... Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host ... The viral core is completely uncoated as early expression ends, releasing the viral genome into the cytoplasm. At this point, ... producing all viral structural proteins. Assembly of progeny virions begins in cytoplasmic viral factories, producing an ...
*  Cassava brown streak virus
"Reovirus core protein mu2 determines the filamentous morphology of viral inclusion bodies by interacting with and stabilizing ... Upon viral entry into the host cell, the virus uncoats its outer protein shell and releases the viral RNA into the host cell's ... The protein P3N-PIPO, a movement protein, may help to initiate cell-to-cell movement and transfer. Potyviruses are known to be ... These inclusion bodies are thought to be sites of viral replication and assembly, making then an important factor in the viral ...
*  Alphaentomopoxvirus
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host ... Core is completely uncoated as early expression ends, viral genome is now free in the cytoplasm. Intermediate phase: ... Fusion with the plasma membrane to release the core into the host cytoplasm. Early phase: early genes are transcribed in the ... "Viral Zone". ExPASy. Retrieved 12 June 2015. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 12 June 2015. Viralzone: ...
*  Parapoxvirus
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host ... Core is completely uncoated as early expression ends, viral genome is now free in the cytoplasm. Intermediate phase: ... Fusion with the plasma membrane to release the core into the host cytoplasm. Early phase: early genes are transcribed in the ... "Viral Zone". ExPASy. Retrieved 15 June 2015. Viralzone: Parapoxvirus ICTV Virus Pathogen Database and Analysis Resource (ViPR ...
*  Entomopoxvirinae
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host ... Core is completely uncoated as early expression ends, viral genome is now free in the cytoplasm. Intermediate phase: ... Fusion with the plasma membrane to release the core into the host cytoplasm. Early phase: early genes are transcribed in the ... Late phase: Late genes are expressed from 140 min to 48 hours post-infection, producing all structural proteins. Assembly of ...
*  Chordopoxvirinae
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host ... Core is completely uncoated as early expression ends, viral genome is now free in the cytoplasm. Intermediate phase: ... Fusion with the plasma membrane to release the core into the host cytoplasm. Early phase: early genes are transcribed in the ... The virus exits the host cell by microtubular outwards viral transport, and existing in occlusion bodies after cell death and ...
*  PSMD7
The calculated theoretical pI of this protein is 6.11. 26S proteasome complex is usually consisted of a 20S core particle (CP, ... "Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein". Nature. 418 (6898): 646-50 ... To recognize protein as designated substrate, 19S complex has subunits that are capable to recognize proteins with a special ... Accordingly, misfolded proteins and damaged protein need to be continuously removed to recycle amino acids for new synthesis; ...
*  Avipoxvirus
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host ... Core is completely uncoated as early expression ends, viral genome is now free in the cytoplasm. Intermediate phase: ... Fusion with the plasma membrane to release the core into the host cytoplasm. Early phase: early genes are transcribed in the ... This suggests avian pox is an emerging viral disease. Mosquitoes that feed on birds are the most consistent and efficient ...