Research has shown that MAL may be involved in vesicular transport of sulfatide and other myelin proteins and lipids to the ... ApoE is a protein that is involved in the transport of many lipids, including cholesterol, and thus, regulates how much ... New Insights into Cellular Functions and Mechanisms of Protein Recognition". Lipid-mediated Protein Signaling. Advances in ... The vaccinia virus has been shown to be able to bind to sulfatide through the L5 and A27 membrane proteins on the virus. It has ...
Members of the RAB family of RAS-related GTP-binding proteins are important regulators of vesicular transport and are located ... Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. Ras-related protein Rab-7a is involved in ... and endosome-lysosome transport through different protein-protein interaction cascades. RAB7A is also involved in regulation of ... "Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments ...
... a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal ... The encoded protein contains an SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein ... Mizuno E, Kawahata K, Kato M, Kitamura N, Komada M (September 2003). "STAM proteins bind ubiquitinated proteins on the early ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ...
Small GTPases of the RAB superfamily are recognized as key players of the protein machinery involved in vesicular transport and ... Ras-related protein Rab-2B is a protein that in humans is encoded by the RAB2B gene. RAB2B is required for protein transport ... RAB proteins are involved in docking and fusion of transport vesicles with their target membranes. These proteins associate ... RAB2B's main function is regulating vesicle transport and membrane fusion. RAB2B is a human protein whose gene is located in ...
The size of the multinucleated assembled osteoclast allows it to focus the ion transport, protein secretory and vesicular ... Energy-dependent acid transport was verified and the postulated proton pump purified. With the successful culture of ... In addition, it permits the vesicular transcytosis of the mineral and degraded collagen from the ruffled border to the free ... The osteoclast disassembles and digests the composite of hydrated protein and mineral at a molecular level by secreting acid ...
... which is responsible for transporting select cargo proteins between vesicular structures (e.g., endosomes, lysosomes, vacuoles ... where cargo proteins fail to be transported and dysfunctional or unnecessary proteins fail to be degraded. There are numerous ... whereby a heat shock protein 70kDa protein 8 (HSPA8)-containing complex facilitates degradation of proteins containing a KFERQ ... Vergés M (2016-01-01). Jeon KW (ed.). "Retromer in Polarized Protein Transport". International Review of Cell and Molecular ...
... usually present in proteins of the t-SNARE superfamily and has been found in other proteins associated with vesicular transport ... VAMP-Associated Protein A ( or Vesicle-Associated Membrane Protein-Associated Protein A) is a protein that in humans is encoded ... in regulation of lipid transport and metabolism, and in the Unfolded Protein Response (UPR). The protein is divided in three ... proteins containing the FFAT motif and viral proteins. VAPA is able to bind a range of SNARE proteins including syntaxin1A, ...
Vesicular transport proteins, Congenital disorders, Neurodevelopmental disorders). ... also known as KIAA0905 and SEC31-related protein A (SEC31L1), encodes the transport protein SEC31A, a 1220 amino acid protein ... through which membrane and luminal cargo proteins are transported from their site of synthesis to other cellular compartments. ... "Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles". ...
Translocase Vesicular transport protein Endocytosis Membrane+transport+proteins at the U.S. National Library of Medicine ... Often these redox proteins are not considered transport proteins. Every carrier protein, especially within the same cell ... Unlike channel proteins which only transport substances through membranes passively, carrier proteins can transport ions and ... Wikimedia Commons has media related to Membrane transport proteins. "Transport protein" at Dorland's Medical Dictionary ( ...
... may refer to: Signal transducing adaptor protein Vesicular transport adaptor protein Clathrin adaptor protein, ... also known as adaptin This disambiguation page lists articles associated with the title Adaptor protein. If an internal link ...
... vesicular transport and protein degradation are just a few examples. The forkhead associated (FHA) domain of polynucleotide ... Hofmann K, Bucher P (September 1995). "The FHA domain: a putative nuclear signalling domain found in protein kinases and ... The domain is present in a diverse range of proteins, such as kinases, phosphatases, kinesins, transcription factors, RNA- ... To date, genes encoding FHA-containing proteins have been identified in eubacterial, eukaryotic and archaeal genomes. ...
... adaptor proteins.2C vesicular transport "Role of Signal Transducing Adaptor Protein (STAP) Family in Chronic Myelogenous ... Signal transducing adaptor proteins (STAPs) are proteins that are accessory to main proteins in a signal transduction pathway. ... Adaptor proteins contain a variety of protein-binding modules that link protein-binding partners together and facilitate the ... These proteins tend to lack any intrinsic enzymatic activity themselves, instead mediating specific protein-protein ...
... vesicular transport, protein translation and transport, as well as the population dynamics of malaria parasites. Perhaps the ...
... the involved protein is processed for ERAD using a set of factors including the vesicular trafficking machinery that transports ... The Vpu protein of HIV-1 is a protein on the ER membrane and targets newly made CD4 in the endoplasmic reticulum for ... Most evidence suggest that the Hrd1 E3 ubiquitin-protein ligase can function as a retrotranslocon or dislocon to transport ... However, HIV produces the membrane protein Vpu that binds to CD4. The Vpu protein mainly retains the CD4 in the ER by SCFβ-TrCP ...
... vesicular transport, and plasticity in hippocampal neuronal cells". The FASEB Journal. 26 (10): 3980-92. doi:10.1096/fj.12- ... 2012). "Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, ...
In Saccharomyces the Vts1 impacts vesicular transport and sporulation. Protein-protein interactions through SAM domains ... Proteins having such domains were also shown to recognize and interact with RNA structures of similar shape to the Smaug ... Schultz J, Ponting CP, Hofmann K, Bork P (January 1997). "SAM as a protein interaction domain involved in developmental ... The protein is found in Saccharomyces cerevisiae and several eukaryotes. ...
Advani RJ, Yang B, Prekeris R, Lee KC, Klumperman J, Scheller RH (1999). "VAMP-7 mediates vesicular transport from endosomes to ... Vesicle-associated membrane protein 7 (VAMP-7), is a protein that in humans is encoded by the VAMP7 gene also known as the or ... VAMP-7 is a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor ... VAMP-7 localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes ...
... possible role of vesicular transport in axonal elongation". Brain Research. Molecular Brain Research. 85 (1-2): 1-12. doi: ... Gamma-aminobutyric acid receptor-associated protein-like 2 is a protein that in humans is encoded by the GABARAPL2 gene. ... possible role of vesicular transport in axonal elongation". Brain Research. Molecular Brain Research. 85 (1-2): 1-12. doi: ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ...
... possible role of vesicular transport in axonal elongation". Brain Research. Molecular Brain Research. 85 (1-2): 1-12. doi: ... Gamma-aminobutyric acid receptor-associated protein is a protein that in humans is encoded by the GABARAP gene. Gamma- ... Kanematsu T, Hirata M (Apr 2002). "[The analysis of protein-protein interaction with special reference to PRIP-1]". Nihon ... possible role of vesicular transport in axonal elongation". Brain Research. Molecular Brain Research. 85 (1-2): 1-12. doi: ...
... possible role of vesicular transport in axonal elongation". Brain Research. Molecular Brain Research. 85 (1-2): 1-12. doi: ... December 2000). "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. ... Ulk1/2 is an important protein in autophagy for mammalian cells, and is homologous to ATG1 in yeast. It is part of the ULK1- ...
This functions include signaling, vesicular trafficking, lipid metabolism and nonvesicular sterol transport. ORPs have been ... The oxysterol-binding protein (OSBP)-related proteins (ORPs) are a family of lipid transfer proteins (LTPs). Concretely, they ... It is thought that it takes part in protein-protein interactions, but it is not known for certain. In some proteins, it also ... Universal protein resource accession number Q96SU4 for "Oxysterol-binding protein-related protein 9 - Homo sapiens (Human)" at ...
This gene encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into ... Vesicular glutamate transporter 3 (VGLUT3) is a protein that in humans is encoded by the SLC17A8 gene. ... 2007). "Docking and homology modeling explain inhibition of the human vesicular glutamate transporters". Protein Sci. 16 (9): ... 2006). "Distribution of vesicular glutamate transporters in rat and human retina". Brain Res. 1082 (1): 73-85. doi:10.1016/j. ...
"VESICULAR TRANSPORT. A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly". Science. 349 ( ... Luminal proteins: Proteins found in the lumen of the Golgi complex that need to be transported to the lumen of the ER contain ... COPI is a coatomer, a protein complex that coats vesicles transporting proteins from the cis end of the Golgi complex back to ... This type of transport[clarification needed] is retrograde transport, in contrast to the anterograde transport associated with ...
... protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... Chow VT, Quek HH (1997). "Alpha coat protein COPA (HEP-COP): presence of an Alu repeat in cDNA and identity of the amino ... "Entrez Gene: COPA coatomer protein complex, subunit alpha". Gerich B, Orci L, Tschochner H, Lottspeich F, Ravazzola M, Amherdt ...
Fast transport involves vesicular contents (like organelles) being moved along microtubules by motor proteins at a rate of 50- ... As a result, most enzymes and large proteins are transported from the soma through the axoplasm. Axonal transport occurs either ... Slow axoplasmic transport involves the movement of cytosolic soluble proteins and cytoskeletal elements at a much slower rate ... Though axonal transport is responsible for most organelles and complex proteins present in the axoplasm, recent studies have ...
The encoded protein participates in the vesicular uptake, storage, and secretion of adenoside triphosphate (ATP) and other ... This gene encodes a member of a family of transmembrane proteins that are involved in the transport of small molecules. ... Sawada K, Echigo N, Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y (2008). "Identification of a vesicular ... Solute carrier family 17 member 9 is a protein that in humans is encoded by the SLC17A9 gene. ...
... transport in COPI vesicles returns many of the lost ER resident proteins back to the endoplasmic reticulum. Forward (or ... In another, COPI vesicular transport moves VTC material to the receiving face of the Golgi apparatus through movement of the ... of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus" (PDF). J. Cell Biol. ... The vesicular-tubular cluster (VTC), also referred to as the endoplasmic-reticulum-Golgi intermediate compartment (ERGIC), is ...
Activators of cholera toxin and critical components of intracellular vesicular transport processes". The Journal of Biological ... ARF requires assistance from other proteins in order to switch between binding to GTP and GDP. GTPase activating proteins (GAPs ... The active form, ARF*GTP, binds to vesicle coat proteins and adaptors, including coat protein I (COPI) and various ... Arp and Sar proteins: A family of GTP-binding proteins with a structural device for 'front-back' communication". EMBO Reports. ...
Other mechanisms of vesicular transport include retrograde transport, the movement of vesicles to the golgi apparatus, or ... v t e v t e (EH-domain-containing proteins, Protein families, All stub articles, Cell biology stubs, Protein stubs). ... Rab proteins have been found to play a major role in endocytotic recycling via SNARE-based vesicle fusion and transport. When ... EHD4 is implicated in vesicular transport from early endosome to ERC as well as in the lysosomal degradation pathway. Recent ...
This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several ... The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, ... The golgins are a family of proteins, of which the protein encoded by this gene is a member, that are localized to the Golgi. ... Golgin subfamily A member 2, also known as 130 kDa cis-Golgi matrix protein 1 (GM130) is a protein that in humans is encoded by ...