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*  Depolarization
"Membrane potential depolarization decreases the stiffness of vascular endothelial cells". Journal of Cell Science. 124: 1936- ... but also to the ability of the vascular endothelium to aid in the regulation of vascular tone, prevention of vascular rigidity ... The endothelium that lines blood vessels is known as vascular endothelium, which is subject to and must withstand the forces of ... Endothelial cells within blood vessels can alter the strength of their structure to maintain the vascular tone of the blood ...
*  Advanced glycation end-product
Increased arterial stiffness Inhibition of vascular dilation by interfering with nitric oxide. Oxidizing LDL. Binding cells- ... They are also believed to play a causative role in the vascular complications of diabetes mellitus. Under certain pathologic ... In the context of cardiovascular disease, AGEs can induce crosslinking of collagen which can cause vascular stiffening and ... AGEs have a range of pathological effects, such as: Increased vascular permeability. ...
*  Durotaxis
"Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: Implications for atherosclerosis". ... ECM stiffness was also noted to influence cytoskeletal stiffness, fibronectin fibril assembly, the strength of integrin- ... "Vascular smooth muscle cell durotaxis depends on substrate stiffness gradient strength". Biophysical Journal. 97 (5): 1313-22. ... Increased liver stiffness (of existing collagen) has actually been shown to precede fibrosis and to be required for the ...
*  Monckeberg's arteriosclerosis
This is probably due to vascular calcification causing increased arterial stiffness, increased pulse pressure and resulting in ... The mechanism of vascular calcification is not fully understood, but probably involves a phenotypic change in the vascular ... Hydroxyapatite is secreted in vesicles that bleb out from vascular smooth muscle cells or pericytes in the arterial wall. ... It is unclear whether Mönckeberg's arteriosclerosis is a distinct entity or forms part of a spectrum of vascular calcification ...
*  Arterial stiffness
Vascular Explorer, and SphygmoCor. The primary sites of end-target organ damage following an increase in arterial stiffness are ... Arterial stiffness may also affect the time at which pulse wave reflections return to the heart. As the pulse wave travels ... Arterial stiffness occurs as a consequence of biological aging and arteriosclerosis. Inflammation plays a major role in ... Increased arterial stiffness is associated with an increased risk of cardiovascular events such as myocardial infarction and ...
*  Vascular myelopathy
In diseases such as subarachnoid hemorrhage, signs and symptoms include headache, neck stiffness and back and leg pain. ... Vascular myelopathy (vascular disease of the spinal cord) refers to an abnormality of the spinal cord in regard to its blood ... "Vascular myelopathies-vascular malformations of the spinal cord: presentation and endovascular surgical management". Semin ... The anterior spinal artery has a less efficient supply of blood and is therefore more susceptible to vascular disease. Whilst ...
*  Adhesion (medicine)
Beyond adhesion they can cause stiffness or flexibility problems. There are three general types of adhesions: filmy, vascular, ... Vascular adhesions are problematic. Using Wikipedia for Research "adhesion" at Dorland's Medical Dictionary diZerega, Gere; ...
*  Vascular remodelling in the embryo
In general, the stiffness and resistance of these tissues dictates the degree to which they can be deformed and the way in ... the balance between vascular forces and tissue forces is shifted and some vascular branches may be disconnected or diminished ... The study of vascular or remodelling in the embryo is widely believed to have been pioneered by Thoma in 1893 when he observed ... Therefore, vascular remodelling does not depend on the presence of oxygen and in fact occurs before perfused tissues require ...
*  Geriatric psychology
Vascular dementia, the second most common type of dementia, is the result of a stroke. A geriatric psychologist aids in the ... Parkinson's disease is a movement disorder that has symptoms like tremors, slowing down, stiffness, and impaired balance. A ... "Vascular Dementia , Signs, Symptoms, & Diagnosis". www.alz.org. Retrieved 2016-12-12. "NINDS , Parkinson's Disease Information ... assessment, diagnosing, treatment, and research of vascular dementia. ...
*  Pulse pressure
If the usual resting pulse pressure is consistently greater than 100 mmHg, the most likely basis is stiffness of the major ... and Vascular Biology. 21 (12): 2072-2079. doi:10.1161/hq1201.100223. Retrieved 15 February 2017. CS1 maint: Multiple names: ... and concluded that folic acid is an effective supplement that targets large artery stiffness and may prevent isolated systolic ... and there was no effect on common carotid artery stiffness. Blood pressure Mean arterial pressure Cold pressor test ...
*  Self-healing material
Two main strategies exist for housing these agents, namely capsules and vascular tubes. These capsules and vascular tubes, once ... The stiffness of sandwich structures is high, making it an attractive option for pressurized chambers. For the most part in ... A vascular or fibre-based approach may be more appropriate for self-healing impact damage in fibre-reinforced polymer composite ... Vascular systems have a number of advantages over microcapsule based systems, such as the ability to continuously deliver large ...
*  Disease registry
... the international registry for ambulatory blood pressure and arteral stiffness telemonitoring. Clinical trials registry McNeil ... international database that tracks demographic and clinical outcome data from patients with Gaucher disease Vascular health ...
*  Starfish
The water vascular system of the starfish is a hydraulic system made up of a network of fluid-filled canals and is concerned ... This arrangement enables both easy flexion of the arms by the starfish and the rapid onset of stiffness and rigidity required ... The water vascular system serves to transport oxygen from, and carbon dioxide to, the tube feet and also nutrients from the gut ... Some of the body cavities degenerate but others become the water vascular system and the visceral coelom. The starfish is now ...
*  Vitamin K2
Vascular calcification was shown to appear in warfarin-treated experimental animals within two weeks. Also in humans on OAC ... Zieman, S. J.; Melenovsky, V.; Kass, D. A. (2005). "Mechanisms, pathophysiology, and therapy of arterial stiffness". ... Among consequences of anticoagulant treatment: increased aortic wall stiffness, coronary insufficiency, ischemia, and even ... but there does not seem to be enough vitamin K2 for the carboxylation of osteocalcin in bone and MGP in the vascular system. ...
*  Trabecula
As a result of less trabeculae in the beak, it has a higher stiffness of 1.0 GPa compared to the skull, 0.31 GPa. While the ... because they require increased vascular perfusion of trabeculae. The vascularization by tunneling osteons changes the ... It has a low stiffness and a high coefficient of friction of 0.98 so the implants remain secure without sliding. It is made of ... Trabecular bone has previously been known to increase stiffness by increasing the amount of bone per unit volume or by altering ...
*  Complications of diabetes mellitus
Annals of Vascular Surgery, 20(5), 653-658 Thornalley, P. J. (2005). The potential role of thiamine (vitamin B1) in diabetic ... though no significant difference in the odds of arterial stiffness and hypertension. A 1988 study over 41 months found that ... van Etten et al., found that a single dose of folic acid might help in reducing the risk of vascular complications and ... Various mechanisms are proposed, like alterations to the vascular supply of the brain and the interaction of insulin with the ...
*  Rheumatoid arthritis
In arthritis of non-inflammatory causes, signs of inflammation and early morning stiffness are less prominent with stiffness ... LTB4) increases vascular permeabiltity and stimulates other inflammatory substances. A third meta-analysis looked at fish ... Increased stiffness early in the morning is often a prominent feature of the disease and typically lasts for more than an hour ... Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with the same joints typically ...
*  Cerebrovascular disease
Any of these diseases can result in vascular dementia due to ischemic damage to the brain. The most common presentation of ... Hemorrhagic strokes can present with a very severe, sudden headache associated with vomiting, neck stiffness, and decreased ... This produces heterogeneous areas of ischemia at the affected vascular region, furthermore blood flow is limited to a residual ... attributable to a focal vascular lesion. The neurologic symptoms manifest within seconds because neurons need a continual ...
*  Pulse wave velocity
PWV is used clinically as a measure of arterial stiffness. It is easy to measure invasively and non-invasively in humans, is ... O'Rourke MF (April 1982). "Vascular impedance in studies of arterial and cardiac function". Physiol. Rev. 62 (2): 570-623. PMID ... Blacher J, Guerin AP, Pannier B, Marchais SJ, Safar ME, London GM (May 1999). "Impact of aortic stiffness on survival in end- ... May 2001). "Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients". ...
*  Hypertensive emergency
The vascular injury leads to deposition of platelets and fibrin, and a breakdown of the normal autoregulatory function. ... Increased arterial stiffness, increased systolic blood pressure, and widened pulse pressures, all resulting from chronic ... "Vascular Biology Working Group". Retrieved 2010-04-20. [dead link] Elliot, William J; Varon, Joseph; Bakris, George L. "Drugs ... As the left ventricle becomes unable to compensate for an acute rise in systemic vascular resistance, left ventricular failure ...
*  Eperisone
... acts by relaxing both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as ... thus alleviating stiffness and spasticity, and facilitating muscle movement Eperisone also improves dizziness and tinnitus ... Amyotrophic lateral sclerosis Cerebral palsy Spinocerebellar degeneration Spinal vascular diseases and other ...
*  Aorta
The stiffness of the aorta is associated with a number of diseases and pathologies, and noninvasive measures of the pulse wave ... The vascular wall consists of several layers known as the tunica externa, tunica media, and tunica intima. The thickness of the ... The smooth muscle component does not dramatically alter the diameter of the aorta but rather serves to increase the stiffness ... Measuring the pulse wave velocity (invasively and non-invasively) is a means of determining arterial stiffness. Maximum aortic ...
*  Alagebrium
In addition to this, the formation of AGE crosslinks leads to increased stiffness and loss of function of tissues and organs, ... play an integral role in the architecture of tissues and organs and maintenance of cardiovascular elasticity and vascular wall ... Pharmacologic intervention with alagebrium directly targets the biochemical pathway leading to the stiffness of the ...
*  Blood pressure
Venous pressure is the vascular pressure in a vein or in the atria of the heart. It is much less than arterial pressure, with ... Blood pressure is influenced by cardiac output, total peripheral resistance and arterial stiffness and varies depending on ... systemic vascular resistance (SVR), and central venous pressure (CVP): MAP = ( CO ⋅ SVR ) + CVP {\displaystyle \!{\text{MAP ... this is thought to be due to increased stiffness of the arteries. Differences between left and right arm blood pressure ...
*  Fibrin scaffold
When stiffness of the matrix is more than that of a normal brain, extension of spinal cord and cortical brain neurons is ... In biomedical research, fibrin scaffolds have been used to fill bone cavities, repair neurons, heart valves, vascular grafts ... Its stiffness can be managed by changing the concentration according to needs of surrounding or encapsulated cells. Additional ... The most substantial increase in stiffness is observed in PEG-Fibrinogen conjugated hydrogel after 28 days of mechanical ...
*  Senescence
... damage to collagen of blood vessel walls can lead to vessel-wall stiffness and, thus, hypertension, and vessel wall thickening ... enhance cardiac function and improve vascular reactivity in old mice, alleviate gait disturbance caused by radiation in mice, ...