... and resistance to chemotherapy". Blood. 99 (6): 2179-2184. doi:10.1182/blood.V99.6.2179. PMID 11877295. S2CID 2838185. Ueda M, ... Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular ... January 1998). "Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and ... January 2004). "Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic ...
The blood viscosity refers to the resistance to the movement of blood. It is vital to sustaining the vascular homeostasis in ...
The transportation of water from the vascular tissue into storage cells is a very slow process as it is a high-resistance path ... The water is absorbed into the vascular tissue of the tree, where it can be moved into the tree's parenchyma cells for long- ... The water fluxes from the vascular tissue into the parenchyma cells at the center of the tree with the help of actively ... which would cause the water potentials in the vascular tissue to drop too low and pull water out of the vacuoles in the ...
8 was tested in 1804 hemodialysis patients with a primary fistula or synthetic graft vascular access. After 40 weeks following ... Antibiotic resistance is a subset of antimicrobial resistance. This more specific resistance is linked to bacteria and thus ... Resistance in bacteria can arise naturally by genetic mutation, or by one species acquiring resistance from another. Resistance ... Fungi evolve antifungal resistance. Viruses evolve antiviral resistance. Protozoa evolve antiprotozoal resistance, and bacteria ...
There is mechanistic and epidemiological evidence for a link between insulin resistance and HFpEF. This pro-inflammatory state ... Specifically, loss of cardiac reserve, diminished vascular compliance, and diastolic dysfunction are characteristic of both ... It is thought that increased pressure, in concert with a pro-inflammatory state (insulin resistance, obesity), encourage ... may also induce changes in the vascular endothelium of the heart. Specifically, by reducing availability of nitric oxide, an ...
... and is suitable for use in all catheter based vascular access devices. Bacterial resistance against taurolidine has never been ... Side effects and the induction of bacterial resistance is uncommon. It is also being studied as a treatment for cancer. It is ... taurolidine also promotes apoptosis by inducing various apoptotic factors and suppresses the production of vascular endothelial ... and also appears to preclude susceptibility to resistance mechanisms. Taurolidine binding to lipopolysaccharides (LPS) prevents ...
An allele of PIEZO1, E756del, results in a gain-of-function mutation, resulting in dehydrated RBCs and conveying resistance to ... November 2014). "Piezo1 integration of vascular architecture with physiological force". Nature. 515 (7526): 279-282. Bibcode: ... PIEZO1 channels are pivotal integrators in vascular biology. ...
Design principles of vascular beds. Pries AR, Secomb TW, Gaehtgens P. Circ Res 1995; 77(5): 1017-1023. Resistance to blood flow ... Coronary vascular regulation, remodelling, and collateralization: mechanisms and clinical implications on behalf of the working ... From 1996 to 2011 Pries was General Secretary of the German Society for Microcirculation and vascular biology, and General ... evidence for a novel concept of vascular network maturation. Nitzsche B, Rong WW, Goede A, Hoffmann B, Scarpa F, Kuebler WM, ...
... -A has been shown to facilitate the binding of free fatty acids to TLR4 receptors, thereby inducing insulin resistance in ... Fetuin-A was originally discovered to be an inhibitor of vascular calcification in early 1990s. Since then many more roles have ... Fetuin-A has been demonstrated to play an important role in free fatty acid induced insulin resistance in the liver. Increased ... "Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance" (PDF). Nature Medicine. 18 (8): 1279 ...
Resistance to antibiotics is frequently the result of action of MFS resistance genes. Mutations in MFS transporters have also ... been found to be cause neurodegerative disease, vascular disorders of the brain, and glucose storage diseases. Disease ... Paulsen IT, Brown MH, Littlejohn TG, Mitchell BA, Skurray RA (April 1996). "Multidrug resistance proteins QacA and QacB from ... or drug resistance. The OAT1 transporter transports a number of nucleoside analogs central to antiviral therapy. ...
... is that abnormal vascular control in diabetic nephropathy leads to a reduction in afferent glomerular arteriolar resistance and ... NF-κB and the activation of growth factors TGF-B and vascular endothelial growth factor (VEGF). These factors, along with the ... an increase in efferent glomerular arteriolar resistance, leading to a net increase in renal blood flow (RBF) and glomerular ...
... function of vascular smooth muscle regulates the lumenal diameter of the small arteries-arterioles called resistance arteries, ... Vascular smooth muscle tumors are very rare. They can be malignant or benign, and morbidity can be significant with either type ... In the walls of blood vessels, and lymph vessels, (excluding blood and lymph capillaries) it is known as vascular smooth muscle ... The Rhoa and Rac portion of the signaling pathway provides a calcium-independent way to regulate resistance artery tone. To ...
This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth ... This protein is a member of the MRP subfamily which is involved in multi-drug resistance. ... "Protein kinase C-epsilon induces caveolin-dependent internalization of vascular adenosine 5'-triphosphate-sensitive K+ channels ...
The climate encourages restoration of the general tonus of the human body and resistance towards illnesses[citation needed]. ... The climatotherapy of this zone is used to treat: cardio-vascular system diseases (first stage of essential hypertension; ...
The assumption at that time was that fluoride by way of the blood vascular system would be incorporated into tooth substance ... during tooth development, and positively affect caries resistance. Mühlemann was able to demonstrate that fluoride was also ...
... fatigue resistance, motor performance, and connective tissue integrity. In addition, there are cardiopulmonary and vascular ... Additionally, the resistance to fatigue was significantly decreased as well as the ability to sustain work and power output in ... This likely reflects use of these muscles during bed rest to adjust body position and to reduce the potential for vascular ... Akima, H; Kubo, K; Kanehisa, H; Suzuki, Y; Gunji, A; Fukunaga, T (May 2000). "Leg-press resistance training during 20 days of 6 ...
2005 to investigate the mechanism of resistance provided by Lr21 against wheat leaf rust in hexaploid wheat. RNAi is under ... The molecules are absorbed into the plants' vascular system and poison insects feeding on them. Another approach involves ... This would allow faster adaptation to resistance. Such approaches would require low cost sources of dsRNAs that do not ... While it was known that plants expressing virus-specific proteins showed enhanced tolerance or resistance to viral infection, ...
... in vascular plants. Finally, lignin also confers disease resistance by accumulating at the site of pathogen infiltration, ... Thus, lignin makes it possible for the plant's vascular tissue to conduct water efficiently. Lignin is present in all vascular ... Lignin fills the spaces in the cell wall between cellulose, hemicellulose, and pectin components, especially in vascular and ... 2006). "Bark decay by the white-rot fungus Lentinula edodes: Polysaccharide loss, lignin resistance and the unmasking of ...
PHA resistance exercise promoted cardiovascular adaptations, with a decrease in the power spectral component of vascular ... This investigation also want to emphasize the beneficial effects of this particular resistance exercise training, considering ...
Biopsy of the infected nasal tissue showed signs of necrosis and vascular invasion. Cunninghamella echinulata, like other ... members of the genus, exhibit strong resistance to the antifungal polyene, amphotericin B with a MIC (Minimum Inhibitory ...
... which leads to insulin resistance and the inability of the beta-cells to produce an important peptide that prevents vascular ... The most common vascular complication in patients with Type 2 Diabetes is retinopathy which causes many patients to go blind. ... The defects in pancreatic beta cell function and insulin resistance in peripheral tissues were thought to be the result of ... Epigenetics may play a role in a wide array of vascular complications and in diabetes. The epigenetic variations involved with ...
Various strains tested have shown resistance to beta lactam antibiotics, lincosamides, macrolides, and quinolones. Multiple ... drug-resistant strains were mainly isolated from wounds of patients treated in departments of general surgery and vascular ... amycolatum's characteristic traits is its resistance to a wide range of antibiotics. ...
The Siren turned red with demonic-looking face when faced with resistance and germs. When the ship she was doctor to crashed in ... They possess a binary vascular system (two hearts), and therefore a faster heart rate, as well as a cooler internal body ... Time Lords exhibit various other superhuman abilities, including certain mental powers, and resistance to otherwise harmful ... with unusual electrical activity in the brain and blackened teeth. As the Flood overrun the base with the intent of reaching ...
... "vascular dam". The limited venous drainage builds the blood flow resistance and adrenal venous pressure, resulting in the ... Adrenal gland is vulnerable to hemorrhage due to its special vascular supply. It has rich blood supply via 50 to 60 small ... While the elevated intravascular pressure increases vascular wall tension proportionally, hemorrhage occurs when the tension ...
... in particular those of vascular origin. Samuel Refetoff - discovered the Refetoff syndrome, resistance to thyrotropin (RTSH) ...
Its function allows it to regulate vascular and embryonic development by inhibiting LPA signaling, which is associated with a ... involving insulin resistance). In humans, PPAP2B emerged as 1 of 13 new loci associated with coronary artery disease by genome- ... Due to the regulatory role of LPP3 in vascular and embryonic development, inactivation of this protein can contribute to ... and vascular development". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831 (1): 126-32. doi: ...
... has specific functions for vasodilation, platelet function, and insulin resistance and in smooth and cardiac muscle. ... HSPB6 is most highly and constitutively expressed in vascular, airway, colonic, bladder, uterine smooth muscle, cardiac muscle ...
This enabled a number of joint reports on vascular disease, and in particular on the relevance of blood lipids, to be based on ... arterial resistance and its contribution to blood pressure has also been studied within the cohort. The randomised controlled ... Thus, while the initial aims of the study focused upon vascular disease, the wealth of data collected has enabled the testing ... reduction in vascular disease, a 35% reduction in cancer (attributable to non-smoking alone) and a 64% reduction in cognitive ...
An impairment of DDAH activity appears to be involved in the elevation of plasma ADMA, and impairment of vascular relaxation ... and insulin resistance). The activity of DDAH is impaired by oxidative stress, permitting ADMA to accumulate. A wide range of ... These findings are consistent with evidence from a number of groups that nitric oxide plays a critical role in vascular ... These insights into the role of DDAH in degrading endogenous inhibitors of NOS, and thereby maintaining vascular NO production ...
The most used selection markers in C. albicans are the CaNAT1 resistance marker (confers resistance against nourseothricin) and ... Excessive release of these pro-inflammatory mediators has been shown to exaggerate systemic inflammation leading to vascular ... "Antifungal Resistance - Fungal Diseases - CDC". www.cdc.gov. 26 June 2017. Retrieved 27 March 2018. "Stop neglecting fungi". ... In the maturation step, the biofilm biomass expands, the extracellular matrix accumulates and drug resistance increases. In the ...