Bone marrow adipocytes (BMAds) originate from mesenchymal stem cell (MSC) progenitors that also give rise to osteoblasts, among ... Flow cytometric quantification can be used to purify adipocytes from the stromal vascular fraction of most fat depots. Early ... These hematopoietic cells are derived from hematopoietic stem cells (HSC) which give rise to diverse cells: cells of the blood ... milieu of cells, and secreted factors. Recent advances in cell surface and intracellular marker identification and single-cell ...
"A Tissue Engineering Approach to Progenitor Cell Delivery Results in Significant Cell Engraftment and Improved Myocardial ... This article details the relationship between endothelial cell nitric oxide synthase (NOS) and vascular homeostasis. He is also ... "A Tissue Engineering Approach to Progenitor Cell Delivery Results in Significant Cell Engraftment and Improved Myocardial ... Doyle, A.M., Nerem, R.M., and Ahsan, T. (2009). "Human Mesenchymal Stem Cells Form Multicellular Structures in Response to ...
"Skeletal muscle neural progenitor cells exhibit properties of NG2-glia". Experimental Cell Research. 319 (1): 45-63. doi: ... A lack of pericytes also causes an upregulation of vascular endothelial growth factor (VEGF), leading to vascular leakage and ... and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation ... These cells communicate with endothelial cells via gap junctions, and in turn cause endothelial cells to proliferate or be ...
Links Vascular Smooth Muscle Cell Apoptosis, Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway ... and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells". Oncogene ... Links Vascular Smooth Muscle Cell Apoptosis, Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway ... 2018) demonstrated that FOXO3a activation in vascular smooth muscle cells induces prominent apoptosis and extracellular matrix ...
Drug-eluting stents inhibit the growth of endothelial cells and vascular smooth muscle cells, which are essential for in-stent ... Coronary Artery Stent Drug-Eluting Stent Antiplatelet drug Endothelial Progenitor Cells Coronary Artery Disease Interventional ... Due to inhibition of vital vascular system cells, this causes risk of stent thrombosis, and, thus, patients with drug-eluting ... endothelial progenitor cell capturing stent vs. the Taxus Liberté stent in patients with de novo coronary lesions with a high- ...
identified nine cell types. They include endothelial cells that line capillaries (45% of cells), fibro-adipogenic progenitors ( ... "Identification of underexplored mesenchymal and vascular-related cell populations in human skeletal muscle". Am J Physiol Cell ... of mononuclear cells are muscle stem cells, adjacent to muscle fiber cells. Types of lymphoid cells (such as B-cells and T- ... However muscle cells cannot divide to produce new cells, and as a result there are fewer muscle cells in an adult than in a ...
Alpha toxin can activate the immune sensor NLRP3 in mammalian cells, causing the cells to die and release inflammatory ... One of the more aggressive progenitors of gas gangrene, C. septicum infection progresses very rapidly, with a mortality rate of ... Sites prone to infection are those with poor vascular supply, although because of pH, electrolyte and osmotic differences, the ... thus disrupting the ionic equilibrium within the cell. Alpha toxin binds GPI-anchored cell surface receptors including the ...
... cancer cells, kidney and epithelial cells ). In vitro, VEGF-A has been shown to stimulate endothelial cell mitogenesis and cell ... in the role of neurons because they too need vascular supply and abolishing the expression of VEGFA from neural progenitors ... These cells will secrete the signaling molecule vascular endothelial factor A (VEGFA) which will recruit the angioblasts ... VEGF-A shows prominent activity with vascular endothelial cells, primarily through its interactions with the VEGFR1 and -R2 ...
... and dendritic cells arise from a common bone marrow progenitor cell subset". Immunity. 3 (4): 459-73. doi:10.1016/1074-7613(95) ... Müllerian adenosarcoma Uterine high-grade leiomyosarcoma Uterine rhabdomyosarcoma Vascular tumors Epithelioid ... Some benign T cells can be CD10+ Clear cell renal cell carcinoma (Clear cell RCC) CD10+ distinguishes renal cell carcinoma, ... Follicular lymphoma (follicle centre cell lymphoma) are CD10+. Burkitt Lymphoma cells are CD10+. CD10+ diffuse large B cell ...
One theory suggests that PCD is an adaptive mechanism to regulate the number of progenitor cells. In humans, PCD in progenitor ... Results of this research suggest that mitochondria play the same key role in vascular plant PCD as in other eukaryotic cells. ... Cell death in arthropods occurs first in the nervous system when ectoderm cells differentiate and one daughter cell becomes a ... 2012). "Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death". Cell. 149 (5): 1060-1072. doi:10.1016/j.cell.2012.03. ...
... can be used to mark endothelial progenitor cells which are critical to tumor growth and angiogenesis. Targeting ID1 results ... endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells ... September 2010). "Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells ... Ruzinova MB, Benezra R (August 2003). "Id proteins in development, cell cycle and cancer". Trends in Cell Biology. 13 (8): 410- ...
The progenitor cells which will become CNCCs are found in the epiblast about Henson's node. Progenitor cells are brought into ... The CNCCs themselves are the precursors to vascular smooth muscle cells and cardiac neurons. For example, CNCCs are required ... glial cells, pigment-containing cells in skin, skeletal tissue cells in the head, and many more. Cardiac neural crest cells ( ... Neural crest cells are a group of temporary, multipotent (can give rise to some other types of cells but not all) cells that ...
Multiple isoforms of MAP4K4 can be present at any given time in the same cell but the abundance of each isoform in the cell ... Atherosclerosis is the result of an inflammatory response to lipid-mediated vascular damage. It has been identified that ... Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) - also known as hepatocyte progenitor kinase-like/germinal ... Deletion of the MAP4K4 gene appears to affect membrane dynamics in endothelial cells, resulting in reduced cell migration and ...
Some proliferating reactive astrocytes can derive from NG2 progenitor cells in the local parenchyma from ependymal cell ... glutamate The potential contribution to seizure genesis Compromise of blood-brain barrier function as a result of vascular ... Oligodendrocyte precursor cells and C6 glioma cells produce metalloproteinase, which is shown to inactivate a type of ... They protect CNS cells and tissue through various methods, such as uptake of potentially excitotoxic glutamate, adenosine ...
This occurs by conversion of endothelial cells to hematopoietic stem and progenitor cells (HPSCs) - a process called ... CXCL12 was expressed throughout the vascular endothelial cells of the white pulp in spleens of EMH-negative and -positive cases ... This is supported by studies showing that blood leaving the lungs has more platelets and fewer progenitor cells than blood ... These hematopoietic stem cells are further closely associated with endothelial cells throughout human life. Later, they migrate ...
CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes". The Journal of Biological ... transcription of the cell type-restricted ankyrin repeat protein CARP gene through CAGA motif in vascular smooth muscle cells ... and in vascular smooth muscle cells, as a downstream target of TGF-beta/Smad sigmaling in response to balloon injury and ... activin induces CARP in smooth muscle cells". Arteriosclerosis, Thrombosis, and Vascular Biology. 23 (1): 64-8. doi:10.1161/01. ...
They are composed of Isl1+/Flk1+ cardiac progenitor cells (CPCs) that are localized into discrete clusters within a ColIV and ... Moeller BJ, Cao Y, Li CY, Dewhirst MW (May 2004). "Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: ... The GSC niche consists of necessary somatic cells-terminal filament cells, cap cells, escort cells, and other stem cells which ... cell-cell interactions between stem cells, as well as interactions between stem cells and neighbouring differentiated cells, ...
... differentiated cells may regain attributes of progenitor cells. An example is PAX5 factor, which is important in B cell ... and Vascular Biology. 36 (9): 1802-8. doi:10.1161/ATVBAHA.116.307519. PMC 5001901. PMID 27470513. Kimmel, Marek (1 January 2014 ... The lymphoid lineage is composed of T-cells, B-cells and natural killer cells. This is lymphopoiesis. Cells of the myeloid ... All blood cells are divided into three lineages. Red blood cells, also called erythrocytes, are the oxygen-carrying cells. ...
T-cells, and myeloid progenitor cells. As mentioned above the cytokine IFN-γ can be used to activate microglial cells. In ... "Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy". The Journal ... Macrophages and dendritic cells are constantly being used up and replaced by myeloid progenitor cells which differentiate into ... Another difference between microglia and other cells that differentiate from myeloid progenitor cells is the turnover rate. ...
and NIH funded study on Stem Cells by Thom, et al., indicate that HBO is actually beneficial in producing stem/progenitor cells ... "Rationale of hyperbaric oxygenation in cerebral vascular insult". Current Vascular Pharmacology. 8 (1): 35-43. doi:10.2174/ ... A study suggests that exposure to hyperbaric oxygen (HBOT) might also mobilize stem/progenitor cells from the bone marrow by a ... Some research also found evidence of an increase in stem progenitor cells and a decrease in inflammation. Tentative evidence ...
... binds to the erythropoietin receptor on erythroid progenitor cells, stimulating RBC production and ... thrombosis of vascular access, and tumor progression or recurrence. To avoid side effects, it is recommended for patients with ... It stimulates erythropoiesis (increases red blood cell levels) by the same mechanism as rHuEpo (binding and activating the Epo ... Darbepoetin is produced by recombinant DNA technology in modified Chinese hamster ovary cells. It differs from endogenous ...
It is expressed by many cell types, including epithelial cells, endothelial cells, neural progenitor cells and leukocytes. The ... and Vascular Biology. 22 (7): 1200-1207. doi:10.1161/01.ATV.0000021411.53577.1C. PMID 12117738. Taylor PM, Woodfield RJ, ... November 2017). "EMMPRIN overexpression in SVZ neural progenitor cells increases their migration towards ischemic cortex". ... is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by ...
... human neural progenitor (ReN), and pheochromocytoma (PC12) cells. These types of cells are commercially available, relatively ... Current[when?] efforts are focusing on introducing endothelial cells into guided formation cultures in order to create vascular ... traditional 2D cell culture, 3D cell culture, microphysiological systems, and animal models. Traditional two dimensional cell ... and patient derived induced pluripotent stem cells (iPSC). Immortalized cell lines are cells from an organism which have been ...
... and the recruitment of endothelial progenitor cells (EPCs) where the marks are located. Beta-adrenergic receptors are found and ... It also limits the development of new blood vessels that is induced by vascular endothelial growth factor (VEGF). The typical ... VCR is a vinca alkaloid and works by binding to the tubulin in tumor cells and causes cell destruction. ... Blocking the beta-receptors can also initiate apoptosis of the endothelial cells to decrease the symptoms of the hemangioma and ...
... the expansion of multipotential hematopoietic progenitor cells, and more. A specific receptor for this cytokine is highly ... and Vascular Biology. 26 (9): 2090-2095. doi:10.1161/01.ATV.0000232502.88144.6f. PMID 16778121. S2CID 8237021. Hsu YH, Chang MS ... IL-20 is mainly produced by myeloid cells such as monocytes, granulocytes, and dendritic cells but can also be produced by ... Because IL-20 is involved in the promotion of proliferation of epithelial cells it is also linked to the development of cancer ...
2007). "TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration". ... 2006). "Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid ... 2003). "The Human Fn14 Receptor Gene Is Up-Regulated in Migrating Glioma Cells in Vitro and Overexpressed in Advanced Glial ... 2003). "Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells". Biochem. Biophys. Res. ...
125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt ... "miR-125a regulates angiogenesis of gastric cancer by targeting vascular endothelial growth factor A". International Journal of ... On the other hand, high expression of miR-125b was shown to decrease cell proliferation and induces apoptosis. The cell ability ... cell invasion and metastasis. Effects of miR-125 in cancer are cell type dependent. MiR-125 is defined either as an oncogene or ...
"Novel Path to Activation of Vascular Smooth Muscle Cells: Up-Regulation of gp130 Creates an Autocrine Activation Loop by IL-6 ... "A bioactive designer cytokine for human hematopoietic progenitor cell expansion". Nature Biotechnology. 15 (2): 142-145. doi: ... It turned out that hematopoietic stem cells, neural cells, smooth muscle cells and endothelial cells are typical target cells ... Gp130 is expressed on all cells of the human body whereas the Interleukin-6 receptor is only found on few cells such as ...
A single tissue, formed from a single type of progenitor cell or stem cell, often consists of several differentiated cell types ... A vascular plant begins from a single celled zygote, formed by fertilisation of an egg cell by a sperm cell. From that point, ... This occurs when individual cells or groups of cells grow longer. Not all plant cells will grow to the same length. When cells ... These cell divisions are usually rapid with no growth so the daughter cells are half the size of the mother cell and the whole ...
Progenitors of traditional white fat cells and adrenergically induced brown fat do not have the capacity to activate the Myf5 ... These findings may prompt further research into the role played by irisin not only in vascular disorders but also in life span ... muscle cells), adipocytes, and chondrocytes (cartilage cells). The classic population of brown fat cells and muscle cells both ... and brown fat cells without PRDM16 were converted into muscle cells. The mitochondria in a eukaryotic cell utilize fuels to ...
Transiently amplifying progenitor cells. Transiently amplifying (or transit-amplifying) progenitor cells are highly ... "A Specialized Vascular Niche for Adult Neural Stem Cells". Cell Stem Cell. 3 (3): 279-288. doi:10.1016/j.stem.2008.07.025. PMC ... Radial glial cells often divide asymmetrically, producing one new stem cell and one neuronal precursor cell per division. Thus ... The progression from neural stem cell to granule cell in the SGZ can be described by tracing the following lineage of cell ...
Livingston believed that after Progenitor hybridizes with cancer cells, it imparts an ability for them to produce hCG in a ... In 1965, she reported isolation of a variably acid-fast mycobacterium in patients with myocardial vascular disease. During this ... Livingston described Progenitor as an intermittently acid-fast mycobacterium that displayed highly variable growth cycles. ... According to her biography, Progenitor was a pseudonym meaning "ancestral" and the name was chosen because Livingston believed ...