"Vascular endothelial growth factor B, a novel growth factor for endothelial cells". Proc. Natl. Acad. Sci. U.S.A. 93 (6): 2567- ... Other growth factors in this family include vascular endothelial growth factors B and C (VEGF-B, VEGF-C) which are active in ... "Vascular endothelial growth factor: A new member of the platelet-derived growth factor gene family". Biochemical and ... Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In ...

Exogenous leptin can promote angiogenesis by increasing vascular endothelial growth factor levels. Hyperleptinemia produced by ... insulin-like growth factor, growth hormone, glucocorticoids, cytokines, and metabolites. Function The primary function of the ... and that of a permissive factor in puberty, activator of immune cells, activator of beta islet cells, and growth factor. In ... Factors that acutely affect leptin levels are also factors that influence other markers of inflammation, e.g., testosterone, ...

"Interaction between the epidermal growth factor receptor (EGFR) and the vascular endothelial growth factor (VEGF) pathways: a ... VEGF (vascular endothelial growth factor) is often over-expressed in epithelioid sarcoma. This is a critical pathway in ... "Patterns of expression and secretion of vascular endothelial growth factor in malignant soft-tissue tumours". Journal of Cancer ... "Expression of c-Met receptor and hepatocyte growth factor/scatter factor in synovial sarcoma and epithelioid sarcoma". Virchows ...

Adam Gideon King (2002). Estrogen induces uterine angiogenesis through the expression of vascular endothelial growth factor. ...

Inhibitors of vascular endothelial growth factor (VEGF) bevacizumab (Avastin)[unreliable medical source?] Inhibitor of EML4-ALK ... Riely GJ, Politi KA, Miller VA, Pao W (December 2006). "Update on epidermal growth factor receptor mutations in non-small cell ... Tatematsu A, Shimizu J, Murakami Y, Horio Y, Nakamura S, Hida T, Mitsudomi T, Yatabe Y (October 2008). "Epidermal growth factor ... Shigematsu H, Gazdar AF (January 2006). "Somatic mutations of epidermal growth factor receptor signaling pathway in lung ...

Another avenue of research has focused on the use of vascular endothelial growth factor inhibitors to treat psoriasis. Oral ... Weidemann AK, Crawshaw AA, Byrne E, Young HS (September 2013). "Vascular endothelial growth factor inhibitors: investigational ... These genes are on the pathway that upregulate tumor necrosis factor-α and nuclear factor κB, two genes involved in ... Social stigmatization is a risk factor for depression, however, other immune system factors may also be related to this ...

She started working on the vascular endothelial growth factor (VEGF) and its receptor (VEGFR) in ischemia and cancer. After ... Imoukhuede, P.I.; Popel, Aleksander S. (2011). "Quantification and cell-to-cell variation of vascular endothelial growth factor ... Fluorescently Labeled α6 and β3 Subunits Quantification and cell-to-cell variation of vascular endothelial growth factor ... VEGF receptors and platelet-derived growth factor receptors. In 2019 Imoukhuede and Sarah K. England partnered to improve the ...

Vascular endothelial growth factor (VEGF) is one of the main inducers of endothelial cell proliferation and permeability of ... Robinson CJ, Stringer SE (March 2001). "The splice variants of vascular endothelial growth factor (VEGF) and their receptors". ... Fibroblast growth factors comprise the largest family of growth factor ligands at 23 members. The natural alternate splicing of ... an autoinhibitor of the human epidermal growth factor receptor 2 tyrosine kinase, modulates epidermal growth factor signaling ...

Other factors released include interleukin-15 and vascular endothelial growth factor (VEGF). A reasonable understanding of the ... The decidua secretes hormones, growth factors, and cytokines. It has receptors for estrogen, progesterone, growth hormone, and ... Insulin-like growth factor-binding protein 1 (IGFBP1) also called placental protein 12, and PAEP (glycodelin) appear to be ... as well as vascular permeability, is enhanced in the decidualizing endometrium. Its leukocyte population is distinct, with the ...

"Capture of endothelial cells under flow using immobilized vascular endothelial growth factor". Biomaterials. 51: 303-312. doi: ... fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its ... Many growth factors bind to receptors at the cell surface and stimulate cells to progress through the cell cycle and divide. ... In this case, the ligand (called epidermal growth factor, or EGF) binds to the receptor (called EGFR). This activates the ...

Researchers at Beth Israel discovered vascular endothelial growth factor (VEGF) in 1983. The two neighboring hospitals merged ...

Mediators that promote angiogenesis are angiopoietin and vascular endothelial growth factor (VEGF). Prostaglandin E2 promotes ... In juveniles, an arachnoid cyst is a risk factor for subdural hematoma. Other risk factors include taking blood thinners ( ... Factors increasing the risk of a subdural hematoma include very young or very old age. As the brain shrinks with age, the ... Treatment of a subdural hematoma depends on its size and rate of growth. Some small subdural hematomas can be managed by ...

Decreased expression is also observed in cells treated with vascular endothelial growth factor. The protein is thought to be ...

"Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis". Circ. Res. 96 (4): 467-75. doi: ... ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety ... Frank S, Upender S, Hansen SH, Casanova JE (1998). "ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6 ... "ADP-ribosylation factor 6 as a target of guanine nucleotide exchange factor GRP1". J. Biol. Chem. 274 (38): 27099-104. doi: ...

The placental growth factor (PGF) gene is a protein-coding gene and a member of the vascular endothelial growth factor (VEGF) ... Placental growth factor (PGF) is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in ... "Entrez Gene: PGF placental growth factor, vascular endothelial growth factor-related protein". Maglione D, Guerriero V, ... "Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PLGF) genes to human chromosome 6p12-p21 ...

It is also associated with excessive amounts of vascular endothelial growth factor (VEGF). As well as in wet macular ... Zhu Y, Zhang T, Xu G, Peng L (December 2016). "Anti-vascular endothelial growth factor for choroidal neovascularisation in ... typically by binding to or deactivating the transmission of vascular endothelial growth factor ('VEGF'), a signal protein ...

"Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b". Oncogene. 23 (53): 8673-80. doi: ... This RNA binding protein most likely functions in regulating the response to growth factors. ZFP36L1 can degrade transcripts of ... Butyrate response factor 1 is a protein that in humans is encoded by the ZFP36L1 gene. This gene is a member of the TIS11 ... Reppe S, Olstad OK, Rian E, Gautvik VT, Gautvik KM, Jemtland R (November 2004). "Butyrate response factor 1 is regulated by ...

Among his research interests are vasculogenesis, angiogenesis, and vascular endothelial growth factor (VEGF). In 2016, ... "Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels". Cell. Elsevier BV. 131 (3 ...

"Phosphorylated endothelial nitric oxide synthase mediates vascular endothelial growth factor-induced penile erection". Biol ... "Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection". Proc Natl Acad Sci USA. 99 (6): ...

Ahmad, S; Ahmed, A (2004). "Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in ... Ahmed's laboratory has studied vascular growth factors in pregnancy and preeclampsia. Research topics include the enzyme ... Asif Ahmed FRSB is a British-Indian vascular scientist, whose research focuses on reducing the risk of mortality and morbidity ... He held the Inaugural Gustav Born Chair of Vascular Biology and was appointed as the Assistant Principal for International ...

Braithwaite T, Nanji AA, Lindsley K, Greenberg PB (May 2014). "Anti-vascular endothelial growth factor for macular oedema ... "Anti-vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema". Cochrane Database of ... Anti‐tumour necrosis factor agents have been proposed as a treatment for macular oedema due to uveitis but a Cochrane Review ... November 2014). "Prevalence of and risk factors for diabetic macular edema in the United States". JAMA Ophthalmology. 132 (11 ...

Lyttle, D J (Jan 1994). "Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus". Journal of ... An example of this is the pox virus vaccinia which encoded a viral growth factor that is very similar to the human growth ... Lythgoe KA, Morrison LJ, Read AF, Barry JD (2007). "Parasite-intrinsic factors can explain ordered progression of trypanosome ... factor and thought to be stolen from the human genome. Antigenic gift: Occurs when humans deliberately modify a virus's genome ...

Hussain RM, Ciulla TA (September 2017). "Emerging vascular endothelial growth factor antagonists to treat neovascular age- ...

A 2018 Cochrane review also examined the effectiveness of anti-vascular endothelial growth factor drugs and their use for ROP. ... Sankar MJ, Sankar J, Chandra P (January 2018). "Anti-vascular endothelial growth factor (VEGF) drugs for treatment of ... Plus disease can be present as a major complicating factor at any stage. It is characterised by: Significant level of vascular ... This is growth of abnormal new vessels; this may regress, but frequently progresses. Associated with the growth of these new ...

"Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C". J. ... Makinde T, Murphy RF, Agrawal DK (2007). "Immunomodulatory role of vascular endothelial growth factor and angiopoietin-1 in ... share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like ... Dunk C, Shams M, Nijjar S (2000). "Angiopoietin-1 and angiopoietin-2 activate trophoblast Tie-2 to promote growth and migration ...

"Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism ... "16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells". ... Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor ... Holmes K, Roberts OL, Thomas AM, Cross MJ (October 2007). "Vascular endothelial growth factor receptor-2: structure, function, ...

2007) Vascular endothelial growth factor (VEGF) signalling in tumor progression. Crit. Rev. Oncol. Hematol. 62, 179-213. ...

"Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating ... "Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family". ... Conversely, the fibroblast growth factor pathway promotes Notch signaling to keep stem cells of the cerebral cortex in the ... VEGF signaling, which is an important factor for migration and proliferation of endothelial cells, can be downregulated in ...

HIF activates downstream targets such as the vascular endothelial growth factor (VEGF), promoting angiogenesis. Mutations in ... Schmidt MH, Furnari FB, Cavenee WK, Bögler O (May 2003). "Epidermal growth factor receptor signaling intensity determines ... "Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury". Cell Death Discovery. 4 ( ... in patients with glioblastoma are related to the deletion of a part of the extracellular domain of the epidermal growth factor ...

Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells ... Iyer, R. K.; Odedra, D.; Chiu, L. L.; Vunjak-Novakovic, G.; Radisic, M. (2012). "Vascular endothelial growth factor secretion ...

... targeting vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor ... fibroblast growth factor receptor (FGFR) 1, 2, and 3; vascular endothelial growth factor receptor (VEGFR) 1, 2, and 3; and FLT3 ... RTK targets of nintedanib include platelet-derived growth factor receptor (PDGFR) α and β; ... The P-glycoprotein inhibitor ketoconazole is known to increase blood plasma levels of nintedanib by a factor of 1.8; other ...