*Vascular endothelial growth factor

Proteopedia Vascular_Endothelial_Growth_Factor - the Vascular Endothelial Growth Factor Structure in Interactive 3D. ... Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced ... Ribatti D (2005). "The crucial role of vascular permeability factor/vascular endothelial growth factor in angiogenesis: a ... "Transcriptional regulation of vascular endothelial growth factor in cancer". Cytokine Growth Factor Rev. 16 (1): 77-89. doi: ...

*Vascular endothelial growth factor A

... has been shown to interact with: ADAMTS1, CTGF, and NRP1, Vascular endothelial growth ... This gene is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes ... "Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PLGF) genes to human chromosome 6p12-p21 ... "Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis". FASEB ...

*Vascular endothelial growth factor B

1996). "Vascular endothelial growth factor B, a novel growth factor for endothelial cells". Proc. Natl. Acad. Sci. U.S.A. 93 (6 ... VEGF-B is a growth factor that belongs to the vascular endothelial growth factor family, of which VEGF-A is the best-known ... Vascular endothelial growth factor B also known as VEGF-B is a protein that, in humans, is encoded by the VEGF-B gene. ... "Extracellular matrix tenascin-X in combination with vascular endothelial growth factor B enhances endothelial cell ...

*Vascular endothelial growth factor C

... (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular ... Tsai PW, Shiah SG, Lin MT, Wu CW, Kuo ML (Feb 2003). "Up-regulation of vascular endothelial growth factor C in breast cancer ... Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI (Mar 1996). "Vascular endothelial growth factor-related protein: a ligand ... Seipel K, Eberhardt M, Müller P, Pescia E, Yanze N, Schmid V (Oct 2004). "Homologs of vascular endothelial growth factor and ...

*Anti-vascular endothelial growth factor therapy

... , also known as anti-VEGF therapy or anti-VEGF medication, is the use of ... Simha A, Braganza A, Abraham L, Samuel P, Lindsley K (2013). "Anti-vascular endothelial growth factor for neovascular glaucoma ... Virgili G, Parravano M, Evans JR, Gordon I, Lucenteforte E (2017). "Anti-vascular endothelial growth factor for diabetic ... "Anti-vascular endothelial growth factor for macular oedema secondary to central retinal vein occlusion". The Cochrane Database ...

*Vascular endothelial growth factor (VEGF) IRES A

This family represents the vascular endothelial growth factor (VEGF) internal ribosome entry site (IRES) A. VEGF is an ... Page for Vascular endothelial growth factor (VEGF) IRES A at Rfam. ... "Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA ... endothelial cell mitogen with many crucial functions such as embryogenic development and wound healing. The 5' UTR of VEGF mRNA ...

*Therapeutic angiogenesis

Vascular endothelial growth factor 1. Isner JM. Therapeutic angiogenesis: a new frontier for vascular therapy. Vasc Med. 1996 1 ... Spatiotemporal control over growth factor signaling for therapeutic neovascularization. Adv Drug Deliv Rev. 2007 Nov 10;59(13): ...

*VEGFR1

"Entrez Gene: FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)". ... Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to ... Shibuya M (2007). "Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis". ... FLT1 has been shown to interact with PLCG1 and vascular endothelial growth factor B (VEGF-B). VEGF receptors GRCh38: Ensembl ...

*FLT4

Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI (March 1996). "Vascular endothelial growth factor-related protein: a ligand ... This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be ... Petrova TV, Makinen T, Alitalo K (November 1999). "Signaling via vascular endothelial growth factor receptors". Experimental ... "Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 ( ...

*Kinase insert domain receptor

"Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism ... "16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells". Mol ... Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase) also known as vascular endothelial growth factor ... Petrova TV, Makinen T, Alitalo K (1999). "Signaling via vascular endothelial growth factor receptors". Exp. Cell Res. 253 (1): ...

*Molecular processor

Vascular endothelial growth factor (VEGF) and enhanced green fluorescent protein (EGFP) cDNA was ligated to either side of an ... Leung, D.; Cachianes, G; Kuang, W.; Goeddel, D.; Ferrara, N (1989). "Vascular endothelial growth factor is a secreted ... engineered cells produce a bioluminescent marker and a chemotactic growth factor. In this instance, increased fluorescence of ... A key factor that differentiates molecular processors is "the ability to control output" of protein or peptide concentration as ...

*Neuropilin 2

"Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor ... Gluzman-Poltorak Z, Cohen T, Herzog Y, Neufeld G (2000). "Neuropilin-2 is a receptor for the vascular endothelial growth factor ... Gluzman-Poltorak Z, Cohen T, Shibuya M, Neufeld G (2001). "Vascular endothelial growth factor receptor-1 and neuropilin-2 form ... "Entrez Gene: NRP2 neuropilin 2". Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z (1999). "Vascular endothelial growth factor ( ...

*Glaucoma

Simha A, Braganza A, Abraham L, Samuel P, Lindsley K (2013). "Anti-vascular endothelial growth factor for neovascular glaucoma ... "Regulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein ... Risk factors for glaucoma include increased pressure in the eye, a family history of the condition, migraines, high blood ... Positive family history is a risk factor for glaucoma. The relative risk of having primary open-angle glaucoma (P.O.A.G.) is ...

*Primary hypertrophic osteoathropathy

... such as Von Willebrand factor and vascular endothelial growth factor (VEGF). These substances could also have a role in PDP ... 2000). "Vascular endothelial growth factor and hypertrophic osteoarthropathy". Clin Exp Rheumatol. 18: 57-62. Jin Hyun Kim; et ... platelet-derived growth factor (PDGF) and epidermal growth factor (EGF). It has not been described yet what role these ... Von Willebrand factor is a marker of platelet and endothelial activation. This suggests that the activation of endothelial ...

*Mitogen

Some growth factors, such as vascular endothelial growth factor, are also capable of directly acting as mitogens, causing ... This is not true for all growth factors, as some growth factors instead appear to cause mitogenic effects like growth ... "Vascular Endothelial Growth Factor is a Secreted Angiogenic Mitogen". 8 December 1989, Science, Vol. 246, pp 1306-1309. Santen ... Growth factor MAPK/ERK pathway Lectins Bohmer et al. "Cytoskeletal Integrity Is Required throughout the Mitogen Stimulation ...

*Autocrine signalling

Another agent involved in autocrine cancer signaling is vascular endothelial growth factor (VEGF). VEGF, produced by carcinoma ... Weigand, Melanie; Hantel, Pia; Kreienberg, Rolf; Waltenberger, Johannes (2005). "Autocrine vascular endothelial growth factor ... One approach used by tumors to upregulate growth and survival is through autocrine production of growth and survival factors. ... For example, despite widespread expression of epidermal growth factor receptors (EGFRs) and EGF family ligands in non-small- ...

*Neovasculgen

AdisInsight Vascular endothelial growth factor gene therapy - HSCI Page accessed 5 June 2016 "Gene Therapy for PAD Approved". 6 ... it delivers the gene encoding for vascular endothelial growth factor (VEGF). Neovasculogen is a plasmid encoding the CMV ...

*Tesevatinib

... epidermal growth factor receptor 2 (HER2; ERBB2), vascular endothelial growth factor receptor (VEGFR), and ephrin B4 (EphB4). ... June 15, 2007). "Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647". Clin. Cancer ... June 15, 2007). "Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647". Clinical ... including epidermal growth factor receptor (EGFR; ERBB1), ... cell line tesevatinib substantially inhibited the growth of ...

*Malignant pleural effusion

April 2005). "Vascular endothelial growth factor in pleural effusions of different origin". Eur. Respir. J. 25 (4): 600-4. doi: ... been shown to be raised in malignant pleural effusions compared to benign disease include vascular endothelial growth factor ( ... Clinical factors predicting the diagnosis of malignant pleural effusions are symptoms lasting more than 1 month and the absence ...

*Angiogenesis inhibitor

... vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and transforming growth factor-β (TGF-β). These ... Feb 2007). "Vascular endothelial growth factor-targeted therapy in renal cell carcinoma: current status and future directions ... Hugo H. Marti, "Vascular Endothelial Growth Factor", Madame Curie Bioscience Database, Landes Bioscience, retrieved January 25 ... Water Extract Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis Through Inhibition of Reactive Oxygen Species ...

*VEGF receptor

Endothelial_Growth_Factor_Receptor - the Vascular Endothelial Growth Factor Receptor Structure in Interactive 3D Molecular and ... "Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc". Biochemical ... "Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor ... Vascular endothelial growth factor (VEGF) is an important signaling protein involved in both vasculogenesis (the formation of ...

*Aflibercept

"Inhibition of Vascular Endothelial Growth Factor in the Primate Ovary Up-Regulates Hypoxia-Inducible Factor-1{alpha} in the ... Fraser HM, Wilson H, Silvestri A, Morris KD, Wiegand SJ (May 2008). "The Role of Vascular Endothelial Growth Factor and ... It is an inhibitor of vascular endothelial growth factor (VEGF). Aflibercept is being co-developed for cancer treatment by ... Virgili G, Parravano M, Evans JR, Gordon I, Lucenteforte E (2017). "Anti-vascular endothelial growth factor for diabetic ...

*Remitting seronegative symmetrical synovitis with pitting edema

One study suggested a possible role for vascular endothelial growth factor. A study using magnetic resonance imaging found that ... November 2005). "RS3PE syndrome presenting as vascular endothelial growth factor associated disorder". Ann. Rheum. Dis. 64 (11 ... and a negative serum rheumatoid factor. If no underlying disorder can be identified (idiopathic RS3PE), this entity has an ...

*Judah Folkman

"Napoleone Ferrara and the saga of vascular endothelial growth factor". Endothelium. 15 (1): 1-8. doi:10.1080/10623320802092377 ... soon identified the already-known fibroblast growth factor as an angiogenic factor, but the team's work showed that there were ... In these trials they also studied the levels of fibroblast growth factor in the urine of the trial subjects and published that ... basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers". J. Natl. Cancer Inst. 86 (5): 356-61 ...

*Primary peritoneal carcinoma

An association with vascular endothelial growth factor has been observed. Prognosis and treatment is the same as for the most ...

*Catenin

Yi ZY, Feng LJ, Xiang Z, Yao H (2011). "Vascular endothelial growth factor receptor-1 activation mediates epithelial to ... conditional inactivation of the β-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular ... to specifically have vascular endothelium cells deficient in β-catenin showed disrupted adhesion between vascular endothelial ... homeostasis and growth, also make it susceptible to alterations that can lead to abnormal cell behavior and growth. Any changes ...