*  DNA vaccination
Second generation vaccines were developed to reduce the risks from live vaccines. These are subunit vaccines, consisting of ... First generation vaccines are whole-organism vaccines - either live and weakened, or killed forms. Live, attenuated vaccines, ... A veterinary DNA vaccine to protect horses from West Nile virus has been approved. DNA vaccines elicit the best immune response ... Several DNA vaccines are available for veterinary use. Currently no DNA vaccines have been approved for human use. Research is ...
*  HIV vaccine
The trial uses the ALVAC-HIV vaccine and a two-component gp120 protein subunit vaccine with an adjuvant. The trial aims to ... Vaccine Research Center (VRC)- Information concerning Preventive HIV vaccine research studies NIAID HIV vaccine site (DAIDS) ... Global Alliance for Vaccines and Immunization (GAVI) International AIDS Vaccine Initiative (IAVI) AIDS Vaccine Advocacy ... HIV Vaccine Trials Network World AIDS Vaccine Day Sharp, Paul M.; Hahn, Beatrice H. (2011-09-01). "Origins of HIV and the AIDS ...
*  Cubosome
Subunit Vaccine Delivery. pp. 130-131. ISBN 978-1-4939-1417-3. Puvvada, S.; Baral, S.; Chow, G.M.; Qadri, S.B.; Ratna, B.R. ( ...
*  Shingles
They include a live-virus vaccine and a non-live subunit vaccine. A review by Cochrane concluded that the live vaccine was ... Two doses of an adjuvanted herpes zoster subunit vaccine had levels of protection of about 90% at 3.5 years. So far it has been ... The shingles vaccine reduces the risk of shingles by 50 to 90% depending on the vaccine used. It also decreases rates of ... Cunningham, AL (2016). "The herpes zoster subunit vaccine". Expert opinion on biological therapy. 16 (2): 265-71. doi:10.1517/ ...
*  Dengue vaccine
Several vaccine candidates are in development including live attenuated, inactivated, DNA and subunit vaccines. Live attenuated ... Dengue vaccine is a vaccine to prevent dengue fever in humans. The World Health Organization only recommends the vaccine as a ... "Vaccine Development. Dengue Vaccine Initiative". Retrieved 31 July 2015. Roehrig, John T. "Current Status of Dengue Vaccine ... Merck is studying recombinant subunit vaccines expressed in Drosophila cells. Studies are in phase I stage as of 2015. The ...
*  Immunity (medical)
Subunit vaccines are composed of small fragments of disease causing organisms. A characteristic example is the subunit vaccine ... Examples are vaccines against flu, cholera, plague, and hepatitis A. Most vaccines of this type are likely to require booster ... Artificially acquired active immunity can be induced by a vaccine, a substance that contains antigen. A vaccine stimulates a ... There are four types of traditional vaccines: Inactivated vaccines are composed of micro-organisms that have been killed with ...
*  Herpes simplex
Unsuccessful clinical trials have been conducted for some glycoprotein subunit vaccines. As of 2017, the future pipeline ... There is no available vaccine and once infected, there is no cure. Paracetamol (acetaminophen) and topical lidocaine may be ... Koelle DM, Corey L (2008). "Herpes Simplex: Insights on Pathogenesis and Possible Vaccines". Annu Rev Med. 59: 381-95. doi: ... Research has gone into vaccines for both prevention and treatment of herpes infections. ...
*  ADAS (company)
Isolation of subunit vaccine candidates for application within veterinary medicine. Development of immunoreagents and their ...
*  Vaccine
... vaccine), a fragment of it can create an immune response.[citation needed] Examples include the subunit vaccine against ... Examples include the polio vaccine, hepatitis A vaccine, rabies vaccine and some influenza vaccines.[citation needed] Some ... The first DIVA vaccines (formerly termed marker vaccines and since 1999 coined as DIVA vaccines) and companion diagnostic tests ... and the hemagglutinin and neuraminidase subunits of the influenza virus.[citation needed] Subunit vaccine is being used for ...
*  Cholera vaccine
Graves PM, Deeks JJ, Demicheli V, Jefferson T (2010). "Vaccines for preventing cholera: killed whole cell or other subunit ... The first vaccines used against cholera were developed in the late 1800s. They were the first widely used vaccine that was made ... The first vaccines used against cholera were developed in the late 19th century. They were the first widely used vaccine that ... Oral cholera vaccines were first introduced in the 1990s and oral cholera vaccine is on the World Health Organization's List of ...
*  Cholera
"Vaccines for preventing cholera: killed whole cell or other subunit vaccines (injected)". Cochrane Database Syst. Rev. (8): ... The vaccine that the FDA recommends, Vaxchora, is an oral attenuated live vaccine, that is effective as a single dose. One ... a single copy of the A subunit (part A), and five copies of the B subunit (part B), connected by a disulfide bond. The five B ... Vaccine. 23 (21): 2762-2774. doi:10.1016/j.vaccine.2004.11.044. PMID 15780724. Choe, Chongwoo; Raschky, Paul A. (January 2016 ...
*  ISCOM
"Immunogenicity and efficacy of recombinant subunit vaccines against phocid herpesvirus type 1". Vaccine. 21 (19-20): 2433-40. ... adjuvanted influenza vaccine". Vaccine. 21 (9-10): 946-9. doi:10.1016/S0264-410X(02)00545-5. PMID 12547607. Isconova's homepage ... The complex displays immune stimulating properties and is thus mainly used as a vaccine adjuvant in order to induce a stronger ... Vaccine. 20 (1-2): 158-63. doi:10.1016/S0264-410X(01)00262-6. PMID 11567760. Mooij, P; Nieuwenhuis, I. G; Knoop, C. J; Doms, R ...
*  Vi capsular polysaccharide vaccine
... it is a subunit vaccine. A newer conjugate form of the vaccine (Vi bound to a non-toxic recombinant Pseudomonas aeruginosa ... For an overview of vaccines against typhoid fever, see Typhoid vaccine. The Vi capsular polysaccharide vaccine (or ViCPS) is ... To maintain immunity, the vaccine should be repeated every three years. The vaccine offers effective protection the first year ... The vaccine may be used in endemic areas in order to prevent typhoid. It is also commonly used to protect people who are ...
*  Anthrax
New second-generation vaccines currently being researched include recombinant live vaccines and recombinant subunit vaccines. ... The human vaccine for anthrax became available in 1954. This was a cell-free vaccine instead of the live-cell Pasteur-style ... "Anthrax and Anthrax Vaccine - Epidemiology and Prevention of Vaccine-Preventable Diseases Archived 24 August 2012 at the ... The French scientist Louis Pasteur developed the first effective vaccine in 1881. Human anthrax vaccines were developed by the ...
*  Breakthrough infection
The presence of maternal antibodies in infants limits the efficacy of inactivated, attenuated and subunit vaccines. Maternal ... Vaccines may fail to provide immunity if the vaccine is of poor quality when administered. A vaccine loses potency if it is ... The mumps vaccine is a component of the Measles, Mumps and Rubella vaccine (MMR). The mumps vaccine, specifically, is 88% ... Indeed, vaccines, including the influenza vaccine, Tdap, and pneumococcal vaccines, are less effective in adults over the age ...
*  Henipavirus
... "a vaccine for people would take many more years." The vaccine is a subunit vaccine that neutralises Hendra virus and is ... Vaccine for horses. In November 2012, a vaccine became available for horses. The vaccine is to be used in horses only, since, ... "A recombinant Hendra virus G glycoprotein-based subunit vaccine protects ferrets from lethal Hendra virus challenge". Vaccine. ... While no vaccine currently exists, a recent (2012) study of a trial vaccine developed using the outer proteins of Hendra virus ...
*  Gajendra Pal Singh Raghava
In 2001, his group also focused on "Computer aided vaccine design" with emphasis on subunit vaccine design. Since 2006, his ...
*  Virus
These vaccines use only the capsid proteins of the virus. Hepatitis B vaccine is an example of this type of vaccine. Subunit ... Vaccines can consist of live-attenuated or killed viruses, or viral proteins (antigens). Live vaccines contain weakened forms ... Yellow fever vaccines and international travelers. Expert Review of Vaccines. 2008;7(5):579-87. doi:10.1586/14760584.7.5.579. ... Smallpox vaccines for biodefense: need and feasibility. Expert Review of Vaccines. 2008;7(8):1225-37. doi:10.1586/14760584.7. ...
*  Chlamydophila pneumoniae
Identification of immunogenic antigens is critical for the construction of an efficacious subunit vaccine against C. pneumoniae ... There is currently no vaccine to protect against Chlamydophila pneumoniae. ...
*  Computational immunology
"Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle ... March 2005). "HIV vaccine development by computer assisted design: the GAIA vaccine". Vaccine. 23 (17-18): 2136-48. doi:10.1016 ... "Exploring Leishmania secretory proteins to design B and T cell multi-epitope subunit vaccine using immunoinformatics approach ... donovani candidate peptide vaccines". Human Vaccines and Immunotheraputics. 8 (12): 1769-74. doi:10.4161/hv.21881. PMC 3656064 ...
*  Bluetongue disease
... a problem which could be resolved using next-generation subunit vaccines currently in development. In January 2015, Indian ... A vaccine for this is now available in the UK, produced by Intervet. Fort Dodge Animal Health has their vaccines available for ... "Evaluation of the immunogenicity of an experimental DIVA subunit vaccine against Bluetongue virus serotype 8 in cattle". ... Vaccine companies Fort Dodge Animal Health (Wyeth), Merial and Intervet were developing vaccines against serotype 8 (Fort Dodge ...
*  Anthrax Vaccine Adsorbed
AVA is classified as a subunit vaccine that is cell-free and containing no whole or live anthrax bacteria. The antigen ( ... For anthrax vaccines generally, see Anthrax vaccines. Anthrax Vaccine Adsorbed (AVA) - also called MDPH-PA or MDPH-AVA; trade ... U.S. anthrax vaccine package insert Gulf War Syndrome Fact or Fiction. Anthrax.osd.mil - 'AVIP: Anthrax Vaccine Immunization ... to supply up to 75 million doses of a recombinant anthrax vaccine, for $877 million. To be acceptable to HHS, this vaccine was ...
*  Influvac
Abbott acquired the vaccines sub-unit from Solvay Pharmaceuticals included in its $6.2 billion purchase and the sub-unit ... "Trivalent inactivated subunit influenza vaccine Influvac: 25-Year experience of safety and immunogenicity". Vaccine. Elsevier. ... Influvac is a sub-unit vaccine produced and marketed by Abbott Laboratories. It contains inactivated purified surface fragments ... Approximately $850 million of sales revenue from vaccines was reported by Solvay Pharmaceuticals in 2009. Giezeman, K.M.; J. ...
*  Antiviral drug
Recently "subunit" vaccines have been devised that consist strictly of protein targets from the pathogen. They stimulate the ... Low vaccine-preventable disease rates as a result of herd immunity also make vaccines seem unnecessary and leave many ... Vaccines are very effective on stable viruses, but are of limited use in treating a patient who has already been infected. They ... These vaccines can, in very rare cases, harm the host by inadvertently infecting the host with a full-blown viral occupancy. ...
*  Influenza research
Novartis has said that Optaflu is a subunit vaccine, meaning it contains individual viral proteins rather than whole virus ... polio vaccine, measles-mumps-rubella vaccine, chickenpox vaccine). In this system, viruses are grown in closed systems such as ... Vaccine manufacturing companies are being encouraged to increase capacity so that if a pandemic vaccine is needed, facilities ... Vaccine production capacity: The protective immune response generated by current influenza vaccines is largely based on viral ...
*  Trimeric autotransporter adhesin
Structure: The neck domain is a homotrimer, where three of the same subunits associate. All three subunits are arranged in such ... 2002). "NadA, a novel vaccine candidate of Neisseria meningitidis". J Exp Med. 195 (11): 1445-54. doi:10.1084/jem.20020407. PMC ... Homotrimerisation is a process whereby three of the same subunits, associate to make a complex of three identical YadA proteins ...
*  Stephen Straus
... including a glycoprotein subunit vaccine. With William Ruyechan and John Hay, Straus cloned VZV and mapped its genome. They ... for the Shingles Prevention Study Group (2005), "A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults ... With Lawrence Corey and David M. Knipe, Straus developed prophylactic and therapeutic vaccines against HSV, ... as well as antiviral drugs and vaccines. He researched the mechanisms by which HSV establishes latency and later recurs. His ...