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*  DNA vaccination
If this capsid protein is included in the DNA, the resulting vaccine can combine the potency of a live vaccine without ... Second generation vaccines were developed to reduce the risks from live vaccines. These are subunit vaccines, consisting of ... First generation vaccines are whole-organism vaccines - either live and weakened, or killed forms. Live, attenuated vaccines, ... A veterinary DNA vaccine to protect horses from West Nile virus has been approved. DNA vaccines elicit the best immune response ...
*  Vaccinia
Vaccine potency and efficacy prior to the invention of refrigerated methods of transportation was unreliable. The vaccine would ... Unlike vaccines that use weakened forms of the virus being vaccinated against, the Vaccinia virus vaccine cannot cause a ... Other poxviruses are also used as live recombinant vaccines. The original vaccine for smallpox, and the origin of the idea of ... "Notice to Readers: Newly Licensed Smallpox Vaccine to Replace Old Smallpox Vaccine". MMWR Morb. Mortal. Wkly. Rep. 57 (8): 207- ...
*  SRD
... devices with low transmission power Single-radial-immunodiffusion an immunological technique used to quantify vaccine potency ...
*  George Siber bibliography
"Reappraisal of existing methods for potency testing of vaccines against tetanus and diphtheria". Vaccine. 13 (11): 965-6. doi: ... "Reappraisal of existing methods for potency testing of vaccines against tetanus and diphtheria". Vaccine. 13 (11): 965-6. doi: ... "Phase 1 trial of a 13-valent pneumococcal conjugate vaccine in healthy adults". Vaccine. 25 (33): 6164-6. doi:10.1016/j.vaccine ... Gupta, RK; Siber, GR (1996). "Use of in vitro Vero cell assay and ELISA in the United States potency test of vaccines ...
*  Expanded Program on Immunization (Philippines)
To ensure the optimal potency of vaccines,a careful attention is needed in handling practices at the country level. These ... "A Look at Each Vaccine: Hepatitis B Vaccine". Vaccine Education Center. The Children's Hospital of Philadelphia. Archived from ... vaccine system is practiced to assure that all vaccines are utilized before its expiry date. Proper arrangement of vaccines and ... Department of Vaccines and Biologicals (December 2000). "WHO Recommendations for Diluents" (PDF). Vaccines and Biologicals ...
*  Efficacy
Potency (pharmacology) Vaccine efficacy Holford NHG & Sheiner LB (1981). "Understanding the dose-effect relationship: Clinical ... a property known as potency. In medicine, efficacy is the capacity for beneficial change (or therapeutic effect) of a given ...
*  Poliomyelitis eradication
Another challenge has been maintaining the potency of live (attenuated) vaccines in extremely hot or remote areas. The oral ... The risk of vaccine-derived polio will persist long after the switch to inactivated vaccine, since a small number of chronic ... Due to shortages in the global supply of injectable vaccine, an emergency campaign was launched using vaccine at one fifth the ... Mutated vaccine strains can also result in polio, and so-called circulating vaccine-derived cases of type 1 (cVDPV1) and 2 ( ...
*  Thiomersal
Unlike other vaccine preservatives used at the time, thiomersal does not reduce the potency of the vaccines that it protects. ... Autism cases in vaccine court: Sugarman SD (2007). "Cases in vaccine court-legal battles over vaccines and autism". N Engl J ... "Vaccines Do Not Cause Autism". www.cdc.gov. Retrieved 2015-11-29. Gołoś, A; Lutyńska, A (2015). "Thiomersal-containing vaccines ... Its use as a vaccine preservative was controversial, and it was phased out from routine childhood vaccines in the European ...
*  Walter Reed Army Institute of Research
Once the vaccine is tested for safety, potency, and identity, the vaccine is released for use in approved human clinical ... Vaccines are produced that will protect Soldiers against diseases that they might encounter in areas of deployment. These ... The PBF at the Forest Glen Annex is a multi-use facility designed and operated for production of vaccines in compliance with ... The Centers focus, respectively, on soldier fitness, brain injury, and sleep management and in the development of vaccines and ...
*  Margaret Pittman
... she demonstrated that the potency assay of the cholera vaccine was directly related to the effectiveness of the vaccine. ... standards for pertussis vaccine, which also became the basis of the international potency requirement of the World Health ... who had pioneered an effective pertussis vaccine but who had been unable to develop a potency assay, Pittman guided the 1949 ... Pittman began work on a standard of potency for a pertussis (whooping cough) vaccine. In collaboration with Dr. Pearl Kindrick ...
*  Anthrax Vaccine Adsorbed
The potency of AVA vaccine lots is routinely determined both by the survival rates of parenterally challenged guinea pigs and ... For anthrax vaccines generally, see Anthrax vaccines. Anthrax Vaccine Adsorbed (AVA) - also called MDPH-PA or MDPH-AVA; trade ... U.S. anthrax vaccine package insert Gulf War Syndrome Fact or Fiction. Anthrax.osd.mil - 'AVIP: Anthrax Vaccine Immunization ... to supply up to 75 million doses of a recombinant anthrax vaccine, for $877 million. To be acceptable to HHS, this vaccine was ...
*  Breakthrough infection
Vaccines may fail to provide immunity if the vaccine is of poor quality when administered. A vaccine loses potency if it is ... The mumps vaccine is a component of the Measles, Mumps and Rubella vaccine (MMR). The mumps vaccine, specifically, is 88% ... Indeed, vaccines, including the influenza vaccine, Tdap, and pneumococcal vaccines, are less effective in adults over the age ... doi:10.1016/j.vaccine.2015.07.085. Siegrist, Claire-Anne (2013). "Vaccine Immunology". Vaccines. Elsevier. ISBN 9781455700905 ...
*  Anthrax Vaccine Immunization Program
The anthrax vaccines were receiving criticism in several scientific circles, because of both potency problems and allegations ... FBI released emails by Ivins showing the vaccine "isn't passing the potency test" and that "no approved lots" were available ... FDA Citizen Petition, Docket 01P-0471 DoD News Article DoD Vaccines.mil Website) "Anthrax Vaccine, GEO's Survey of Guard and ... 1980N-0208 Biological Products; Bacterial Vaccines and Toxoids; Implementation of Efficacy Review; Anthrax Vaccine Adsorbed; ...
*  Nventa Biopharmaceuticals Corporation
These trials were initiated prior to the discovery that potency could be greatly enhanced by addition of a vaccine adjuvant. ... In June 2008, Nventa announced the development of a proprietary vaccine adjuvant, Poly IC - Poly Arginine (Poly-ICR), for use ... The company's lead candidate, HspE7, is a novel therapeutic vaccine intended for the treatment of HPV-related diseases. HspE7 ... Nventa is also developing two additional therapeutic vaccine programs based on its CoVal technology-a Hsp - HBV (hepatitis B) ...
*  Vaccine
Thiomersal is more effective against bacteria, has a better shelf-life, and improves vaccine stability, potency, and safety; ... Examples include the polio vaccine, hepatitis A vaccine, rabies vaccine and some influenza vaccines.[citation needed] Some ... The first DIVA vaccines (formerly termed marker vaccines and since 1999 coined as DIVA vaccines) and companion diagnostic tests ... the HPV vaccine, and the chicken pox vaccine. The World Health Organization (WHO) reports that licensed vaccines are currently ...
*  Mumps vaccine
... and later proved to have low potency. It was introduced in 1985. Monovalent mumps vaccine (Mumpsvax) remained available in the ... MMR Vaccine (Measles, Mumps, Rubella Vaccine) is the most commonly used form of the vaccine, formulated in combination with ... Mumps vaccines are vaccines which prevent mumps. When given to a majority of the population they decrease complications at the ... Mumps vaccines are normally refrigerated, but have a long half-life of 65 days at 23 degrees Celsius. "Mumps virus vaccines" ( ...
*  Polio vaccine
An enhanced-potency IPV (inactivated polio vaccine) was licensed in the United States in November 1987, and is currently the ... The first polio vaccine was the inactivated polio vaccine. It was developed by Jonas Salk and came into use in 1955. The oral ... Oral polio vaccine (OPV) is an attenuated vaccine, produced by the passage of the virus through non-human cells at a sub- ... The inactivated polio vaccines are very safe. Mild redness or pain may occur at the site of injection. Oral polio vaccines ...
*  HspE7
These trials were initiated prior to the discovery that potency could be greatly enhanced by addition of a vaccine adjuvant, ... HPV vaccines Gardasil and Cervarix, which block initial infection with some of the most common sexually transmitted HPV types, ... HspE7 is an investigational therapeutic vaccine candidate being developed by Nventa Biopharmaceuticals for the treatment of ... Lowy DR, Schiller JT (2006). "Prophylactic human papillomavirus vaccines". J. Clin. Invest. 116 (5): 1167-73. doi:10.1172/ ...
*  VVM
... vial vaccines which gives a visual indication of whether the vaccine has been kept at a temperature which preserves its potency ... VVM may refer to: Vaccine vial monitor, a label placed on ...
*  Vaccine vial monitor
... vaccines which gives a visual indication of whether the vaccine has been kept at a temperature which preserves its potency. The ... Zweig, S. (2006). "Advances in vaccine stability monitoring technology". Vaccine. 24 (33-34): 5977-5985. doi:10.1016/j.vaccine. ... In 1996 the vaccine vial monitor was first used in a vaccine project, and by the next year it was widely accepted for use on ... The vaccine vial monitor is intended for use on vaccines which may travel outside of the cold chain, but its use on certain ...
*  H5N1 vaccine
5.9 million full-potency doses) in spite of 0.2 million doses used for research and 1.4 million doses that have begun to lose ... A H5N1 vaccine is an influenza vaccine intended to provide immunization to influenza A virus subtype H5N1. Vaccines have been ... polio vaccine, measles-mumps-rubella vaccine, chickenpox vaccine). In this system, viruses are grown in closed systems such as ... Three H5N1 vaccines for humans have been licensed as of June 2008: Sanofi Pasteur's vaccine approved by the United States in ...
*  Vaccine refrigerator
... failure to adhere to recommended specifications for storage and handling of immunobiologics can reduce or destroy their potency ... Maintenance of vaccine quality is the shared responsibility of all handlers of vaccines from the time a vaccine is manufactured ... Solar power Vaccines Vaccine Handling Tips, Immunization Action Coalition KXN Nigeria Ltd, Nigeria: PV-powered vaccine fridges ... Many vaccines must be stored at low temperatures, some below -15°C, and others between 2 and 8°C. If vaccines are not stored ...
*  Reverse genetics
Vaccines can be created by engineering novel genotypes of infectious viral strains which diminish their pathogenic potency ... This synthesized vaccine strain can then be used as a seed virus to create further vaccines. Vaccines engineered from reverse ... Vaccines created through reverse genetics methods are known as attenuated vaccines, named because they contain weakened ( ... and therefore are taken from the current strain for which the vaccine is being produced to create a well matching vaccine. cDNA ...
*  Center for Biologics Evaluation and Research
CBER's Vaccines and Related Biological Products Advisory Committee meets annually for a discussion and vote concerning the next ... Karen Midthun, M.D. CBER is responsible for assuring the safety, purity, potency, and effectiveness of biologics and related ... Its mission included a mandate to foster the development of new vaccines. The Bureau was transferred from the NIH to the FDA in ... As of 2003, the Vaccine Adverse Event Reporting System was based on a data integration platform from Informatica. The FDA uses ...
*  Ty21a
The vaccine must be stored at 2 to 8 °C, but will retain its potency for 14 days at 25°C. The vaccine offers a statistically ... the other being the Vi capsular polysaccharide vaccine). The vaccine is given by mouth. The vaccine is presented either as ... The vaccine is most commonly used to protect travelers to endemic countries, but some agencies claim that the vaccine could be ... Side effects of this vaccine are mild and rare. Vivotif (manufactured by PaxVax) A newer Vi-rEPA vaccine is being tested for ...
*  RXi Pharmaceuticals
In 2011 RXi Pharmaceuticals acquired Apthera, developer of a peptide vaccine called NeuVax, and changed its name to Galena ... "Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC". Nucleic Acids Res. 38 (11 ...