Loading...
*  Uridine triphosphate
Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1' ...
*  CTP synthetase
Pyrimidine biosynthesis Lieberman I (1956). "Enzymatic amination of uridine triphosphate to cytidine triphosphate". The Journal ... The triphosphate binding site overlaps with that of UTP, but the nucleoside moiety of CTP binds in an alternative pocket ... CTP (cytidine triphosphate) synthetase catalyzes the last committed step in pyrimidine nucleotide biosynthesis: ATP + UTP + ... Kassel KM, Au da R, Higgins MJ, Hines n M, Graves LM (2010). "Regulation of human cytidine triphosphate synthetase 2 by ...
*  Transferase
"Uridyl transferases and the formation of uridine triphosphate; enzymic production of uridine triphosphate: uridine ...
*  Thymidine triphosphate
The corresponding ribonucleoside triphosphate is called uridine triphosphate. It can be used by DNA ligase to create ... Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA. ... Unlike the other deoxyribonucleoside triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its ...
*  CAD (protein)
This enzyme is inhibited by uridine triphosphate (feedback inhibition). In 2015, the first observed pathological mutations of ...
*  Rostral ventromedial medulla
All on-cells showed a response to the non-specific P2 agonist uridine triphosphate (UTP). Activation of on cells by ATP was ...
*  Peptidoglycan
Uridine triphosphate, which is a pyrimidine nucleotide, has the ability to act as an energy source. In this particular reaction ...
*  Nucleotide
UMP is phosphorylated by two kinases to uridine triphosphate (UTP) via two sequential reactions with ATP. First the diphosphate ... They carry packets of chemical energy-in the form of the nucleoside triphosphates ATP, GTP, CTP and UTP-throughout the cell to ... This was in part achieved by the addition of a supportive algal gene that expresses a nucleotide triphosphate transporter which ... Thus, the terms "nucleoside diphosphate" or "nucleoside triphosphate" may also indicate nucleotides. Nucleotides contain either ...
*  Nucleic acid metabolism
After uridine-monophosphate is synthesized, it can react with 2 ATP to form uridine-triphosphate or UTP. UTP can be converted ... In order to synthesize thymidine, a component of DNA which only exists in the deoxy form, uridine is converted to deoxyuridine ... Once the nucleotides are synthesized they can exchange phosphates among one another in order to create mono-, di-, and tri-phosphate ... For example, the uracil base can be combined with ribose-1-phosphate to create uridine monophosphate or UMP. A similar reaction ...
*  Aminoallyl nucleotide
Finally the nitrogenous base and number of phosphates are indicated (i.e. aa-UTP = aminoallyl uridine triphosphate). The goal ... uridine-5′-triphosphate". Tetrahedron Letters. 54 (46): 6264-6266. doi:10.1016/j.tetlet.2013.09.026. Retrieved 9 April 2014. ... For example, 5-(3-Aminoallyl)-Uridine(AA-UTPs) are more effective for high density labeling of DNA than pre-labeling the DNA. ...
*  Purinergic signalling
The signalling effects of uridine triphosphate (UTP) and uridine diphosphate (UDP) are generally comparable to those of ATP. ... Cells release other nucleotides [for example, uridine triphosphate (UTP) and related molecules such as uridine diphosphate (UDP ... Extracellular nucleoside triphosphates and diphosphates are substrates of the ectonucleoside triphosphate diphosphohydrolases ( ... The P2Y6 receptor, which is primarily mediated by uridine diphosphate (UDP), plays a significant role in microglial phagoptosis ...
*  UCK2
Anderson, E.P.; Brockman, R.W. "Feedback onhibition of uridine kinase by cytidine triphosphate and uridine triphosphate". ... UCK2 is one of two human uridine-cytidine kinases. The other UCK protein is uridine-cytidine kinase 1, which shares about 70% ... 2001). "Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases". Mol. Pharmacol. 59 ( ... The protein encoded by this gene catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and ...
*  CTP synthase 1
The catalytic conversion of uridine triphosphate (UTP) to cytidine triphosphate (CTP) is accomplished by the enzyme cytidine-5- ... 1999). "Cytidine triphosphate synthase activity and mRNA expression in normal human blood cells". Biol. Chem. 380 (1): 41-6. ... Thomas PE, Lamb BJ, Chu EH (1988). "Purification of cytidine-triphosphate synthetase from rat liver, and demonstration of ... 1991). "Chromosome mapping of the human cytidine-5'-triphosphate synthetase (CTPS) gene to band 1p34.1-p34.3 by fluorescence in ...
*  Orotidine 5'-phosphate decarboxylase
The function of this enzyme is essential to the de novo biosynthesis of the pyrimidine nucleotides uridine triphosphate, ... cytidine triphosphate, and thymidine triphosphate. OMP decarboxylase has been a frequent target for scientific investigation ... Many studies investigated the binding of a potent inhibitor of OMP decarboxylase, 6-hydroxy uridine monophosphate (BMP, a ... It catalyzes the decarboxylation of orotidine monophosphate (OMP) to form uridine monophosphate (UMP). ...
*  Glucose 6-phosphate
Glucose-1-phosphate can then be combined with uridine triphosphate (UTP) to form UDP-glucose, driven by the hydrolysis of UTP, ...
*  Glycogen branching enzyme
More specifically, during glycogen synthesis, a glucose 1-phosphate molecule reacts with uridine triphosphate (UTP) to become ...
*  Nucleotide salvage
... can phosphorylate UMP into uridine diphosphate, which nucleoside diphosphate kinase can phosphorylate into uridine triphosphate ... forming uridine. Uridine kinase (aka uridine-cytidine kinase) can then phosphorylate this nucleoside into uridine monophosphate ... which converts them to uridine and deoxyuridine, respectively. Alternatively, uridine-cytidine kinase can phosphorylate them ... which nucleoside diphosphate kinase can phosphorylate into cytidine triphosphate or deoxycytidine triphosphate. ...
*  Ledipasvir
Sofosbuvir, on the other hand, is metabolized to a uridine triphosphate mimic, which acts as a RNA chain terminator when ...
*  Cytidylate kinase
Ruffner BW Jr; Anderson EP (1969). "Adenosine triphosphate: uridine monophosphate-cytidine monophosphate phosphotransferase ...
*  DNA microarray
... using aminoallyl uridine triphosphate (aminoallyl-UTP, or aaUTP) and NHS amino-reactive dyes (such as cyanine dyes); for single ... The modified nucleotides (usually in a ratio of 1 aaUTP: 4 TTP (thymidine triphosphate)) are added enzymatically in a low ratio ...
*  P2RY6
"Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on ... for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not ... "Differential regulation of the uridine nucleotide-activated P2Y4 and P2Y6 receptors. SER-333 and SER-334 in the carboxyl ...
*  Glycogen
Energy for glycogen synthesis comes from uridine triphosphate (UTP), which reacts with glucose-1-phosphate, forming UDP-glucose ...
*  Nucleoside-diphosphate kinase
... such as guanosine triphosphate (GTP), cytidine triphosphate (CTP) and uridine triphosphate (UTP). Behind this apparently simple ... and triphosphates (NTP) in a reversible manner to produce nucleotide triphosphates. Many NDP serve as acceptor while NTP are ... when guanosine triphosphate (GTP) produced in the citric acid (Krebs) cycle is converted to adenosine triphosphate (ATP). Other ... In Eukaryotic systems, the role of the NDK is to synthesize nucleoside triphosphates other than ATP. The ATP gamma phosphate is ...
*  Uridine diphosphate
... the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, ... Uridine diphosphate, abbreviated UDP, is a nucleotide diphosphate. It is an ester of pyrophosphoric acid with the nucleoside ... uridine. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil. UDP is an important ...
*  UTP
Uridine triphosphate, in biochemistry Untripentium, a hypothetical chemical element Unifying Theories of Programming Unshielded ...
*  Metabolism
One central coenzyme is adenosine triphosphate (ATP), the universal energy currency of cells. This nucleotide is used to ... made by the sequential addition of monosaccharides by glycosyltransferase from a reactive sugar-phosphate donor such as uridine ...