Glaser L, Melo A, Paul R (1987). "Uridine diphosphate sugar hydrolase. Purification of enzyme and protein inhibitor". J. Biol. ... nucleosidediphosphate-sugar diphosphatase, UDP-sugar hydrolase, and UDP-sugar pyrophosphatase. As of late 2007, 6 structures ... In enzymology, an UDP-sugar diphosphatase (EC 3.6.1.45) is an enzyme that catalyzes the chemical reaction UDP-sugar + H2O ⇌ {\ ... The systematic name of this enzyme class is UDP-sugar sugarphosphohydrolase. Other names in common use include ...
... or UDP-GalNAc is a nucleotide sugar composed of uridine diphosphate (UDP) and N- ... Galactosamine Globoside N-Acetylgalactosamine (N-Acetylglucosamine) GlcNAc "Uridine-diphosphate-n-acetylgalactosamine". pubchem ...
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in ... DNA Nucleoside Nucleotide Oligonucleotide RNA TDP-glucose Uracil Uridine diphosphate Rademacher T, Parekh R, Dwek R (1988). " ... UDP-glucose is used in nucleotide sugar metabolism as an activated form of glucose, a substrate for enzymes called ...
... or UDP-GlcNAc is a nucleotide sugar and a coenzyme in metabolism. It is used by ... and is the biochemical precursor of all nitrogen-containing sugars. To be specific, glucosamine-6-phosphate is synthesized from ...
... and related molecules such as uridine diphosphate (UDP) sugars] that have actions akin to those of ATP Eltzschig HK, Sitkovsky ... The signalling effects of uridine triphosphate (UTP) and uridine diphosphate (UDP) are generally comparable to those of ATP. ... The P2Y6 receptor, which is primarily mediated by uridine diphosphate (UDP), plays a significant role in microglial phagoptosis ... During the blood clotting process, adenosine diphosphate (ADP) plays a crucial role in the activation and recruitment of ...
It is important in nucleotide sugars metabolism, and is the substrate for the transferase B4GALT5. Galactose UDP galactose ... Uridine diphosphate galactose (UDP-galactose) is an intermediate in the production of polysaccharides. ... epimerase Uridine diphosphate "Galactose 1 Phosphate Uridyltransferase Deficiency". StatPearls. StatPearls. 2022. v t e ( ...
It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrophosphate group, the pentose sugar ... Uridine diphosphate, abbreviated UDP, is a nucleotide diphosphate. ... the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, ...
... sequential addition of monosaccharides by glycosyltransferase from a reactive sugar-phosphate donor such as uridine diphosphate ... which reduces the coenzyme NADPH and produces pentose sugars such as ribose, the sugar component of nucleic acids.[citation ... Each nucleotide is composed of a phosphate attached to a ribose or deoxyribose sugar group which is attached to a nitrogenous ... Once inside, the major route of breakdown is glycolysis, where sugars such as glucose and fructose are converted into pyruvate ...
... such as uridine 5-diphosphate(UDP)-galactose, or UDP-glucose to the ceramide unit. The glycosyl-transferase catalyzed reaction ... They consist of a ceramide with a single sugar residue at the 1-hydroxyl moiety. The sugar residue can be either glucose or ... The sugar moiety is linked glycosidically to the C-1 hydroxyl group of ceramide, such as in lactosylceramide. Cerebrosides ... Cerebroside molecules are able form up to eight intermolecular hydrogen bonds between the polar hydrogens of the sugar and the ...
These nucleotide sugars are not physiologically favored and must to be converted from UDP-glucose and Uridine diphosphate N- ... Although the sugar residues are arranged in no particular/discrete order, and thus a heteroglycan, the residues are all linked ... the synthesis of precursor nucleotide sugars has been studied. The galactose component originates from UDP-galactose and the ... galactosaminogalactan is synthesized by polymerization of nucleotide sugars. Although the actual glycosyltransferase ...
UDP-glucuronic acid is a sugar used in the creation of polysaccharides and is an intermediate in the biosynthesis of ascorbic ...
Ginsburg V, Neufeld EF, Hassid WZ (1956). "Enzymatic Synthesis of Uridine Diphosphate Xylose and Uridine Diphosphate Arabinose ... This enzyme participates in nucleotide sugars metabolism. ... diphosphate + UDP-xylose Thus, the two substrates of this ... enzyme are UTP and alpha-D-xylose 1-phosphate, whereas its two products are diphosphate and UDP-xylose. This enzyme belongs to ... uridine diphosphoxylose pyrophosphorylase, and xylose 1-phosphate uridylyltransferase. ...
Uridine Diphosphate: UDP-α-D-Glc, UDP-α-D-Gal, UDP-α-D-GalNAc, UDP-α-D-GlcNAc, UDP-α-D-GlcA, UDP-α-D-Xyl Guanosine Diphosphate ... Cytidine Diphosphate: CDP-D-Ribitol (i.e. CMP-[ribitol phosphate]); though not a sugar, the phosphorylated sugar alcohol ... Nucleotide sugars are the activated forms of monosaccharides. Nucleotide sugars act as glycosyl donors in glycosylation ... Listed below are the structures of some nucleotide sugars (one example from each type). Normal metabolism of nucleotide sugars ...
... uridine 5'-diphosphate-D-xylose 4-epimerase, and UDP-D-xylose 4-epimerase. This enzyme participates in nucleotide sugars ... FEINGOLD DS, NEUFELD EF, HASSID WZ (1960). "The 4-epimerization and decarboxylation of uridine diphosphate D-glucuronic acid by ... Other names in common use include uridine diphosphoarabinose epimerase, UDP arabinose epimerase, ...
Bailey RW, Hassid WZ (November 1966). "Xylan synthesis from uridine-diphosphate-d-xylose by particulate preparations from ... This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism. ... Other names in common use include uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase, 1,4-beta-xylan synthase, xylan ...
... uridine diphosphate galactose pyrophosphorylase, and uridine diphosphogalactose pyrophosphorylase. This enzyme participates in ... galactose metabolism and nucleotide sugars metabolism. As of late 2007[update], 3 structures have been solved for this class of ... ISSELBACHER KJ (1958). "A mammalian uridinediphosphate galactose pyrophosphorylase". J. Biol. Chem. 232 (1): 429-44. PMID ... diphosphate + UDP-galactose Thus, the two substrates of this enzyme are UTP and alpha-D-galactose 1-phosphate, whereas its two ...
FEINGOLD DS, NEUFELD EF, HASSID WZ (1960). "The 4-epimerization and decarboxylation of uridine diphosphate D-glucuronic acid by ... This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism. ... Other names in common use include uridine diphospho-D-galacturonic acid, UDP glucuronic epimerase, uridine diphosphoglucuronic ... epimerase, UDP-galacturonate 4-epimerase, uridine diphosphoglucuronate epimerase, and UDP-D-galacturonic acid 4-epimerase. ...
Uridine diphosphate N-acetylglucosamine and uridine diphosphate glucuronic acid in mung bean seedlings Solms, J. Feingold, D. S ... Sugar nucleotides in the interconversion of sugars of higher plants. Hassid, W. Z., Neufeld, E. F. and Feingold, D. S. Proc. ... Decarboxylation of uridine diphosphate-d-glucuronic acid by an enzyme preparation from hen oviduct. Uridine diphosphate d- ... Uridine diphosphate N-acetylglucosamine and uridine diphosphate glucuronic acid in mung bean seedlings. Enzymatic synthesis of ...
I. Uridine diphosphate-D-glucuronic acid-5-epimerase". The Journal of Biological Chemistry. 237 (3): 638-42. doi:10.1016/S0021- ... This enzyme participates in nucleotide sugars metabolism. It employs one cofactor, NAD+. Jacobson B, Davidson EA (March 1962 ... Other names in common use include uridine diphosphoglucuronate 5'-epimerase, UDP-glucuronic acid 5'-epimerase, and C-5-uronosyl ...
... by being joined via a glycosidic bond to the phosphate group of a nucleotide such as uridine diphosphate (UDP), guanosine ... thymidine diphosphate (TDP), or cytidine monophosphate (CMP). These activated biochemical intermediates are known as sugar ... nucleotides or sugar donors. Many biosynthetic pathways use mono- or oligosaccharides activated by a diphosphate linkage to ... A glycosidic bond or glycosidic linkage is a type of ether bond that joins a carbohydrate (sugar) molecule to another group, ...
Precursors such as uridine diphosphate (UDP), UDP-N-acetyl-D-glucosamine, or glucosamine are used to synthesize galactosamine ... This amino sugar is a constituent of some glycoprotein hormones such as follicle-stimulating hormone (FSH) and luteinizing ... and uridine triphosphate (UTP), UDP, and uridine monophosphate (UMP) decrease. The depletion of high-energy molecules such as ... Additionally, other derivatives of uridine such as UDP-glucose are depleted and this interferes with glycogen synthesis in the ...
Ankel H, Feingold DS (1965). "Biosynthesis of uridine diphosphate D-xylose. 1. Uridine diphosphate glucuronate carboxy-lyase of ... This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism. It employs one cofactor, NAD+. As ... Other names in common use include uridine-diphosphoglucuronate decarboxylase, and UDP-D-glucuronate carboxy-lyase. ...
... becomes uridine, uridine monophosphate (UMP), uridine diphosphate (UDP), uridine triphosphate (UTP), and uridine ... In RNA, uracil binds with a ribose sugar to form the ribonucleoside uridine. When a phosphate attaches to uridine, uridine 5′- ... Uracil readily undergoes addition to ribose sugars and phosphates to partake in synthesis and further reactions in the body. ... Uracil is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes. Uracil is ...
The sole pathway for bilirubin elimination is through the uridine diphosphate glucuronosyltransferase isoform 1A1 (UGT1A1) ... enzyme, which performs a reaction called "glucuronidation". This reaction adds a large sugar to the bilirubin, which makes the ...
The energy for the reaction is gained by the cleavage of uridine diphosphate (UDP). Sucrose is formed by plants, algae and ... such as sanding sugar (also called "pearl sugar", "decorating sugar", nibbed sugar or sugar nibs) is a coarse grain sugar used ... Powdered, 10X sugar, confectioner's sugar (0.060 mm), or icing sugar (0.024 mm), produced by grinding sugar to a fine powder. ... beet sugar is almost always labeled simply as sugar or pure sugar. Interviews with the 5 major beet sugar-producing companies ...
Rudick VL, Weisman RA (1974). "Uridine diphosphate glucose pyrophosphorylase of Acanthamoeba castellanii. Purification, kinetic ... Tsumuraya Y; Yamaguchi, D; Ohzono, H; Hojo, S; Kaneko, S; Ishida, HK; Tsumuraya, Y (2004). "UDP-sugar pyrophosphorylase with ... diphosphate + UDP-monosaccharide Thus, the two substrates of this enzyme are UTP and monosaccharide 1-phosphate, whereas its ... Other names in common use include UDP-sugar pyrophosphorylase', and PsUSP. ...
Various donors, including p-nitrophenyl-β-galactopyranoside, uridine diphosphate galactose and lactose, can be used in ... Human milk oligosaccharides (HMOs), also known as human milk glycans, are short polymers of simple sugars that can be found in ... These have the ability to bind themselves to the glycan receptors (receptors for long chains of connected sugar molecules on ... Bacteria are then converting the lactose into human milk oligosaccharides by decorating it with other sugar monomers. After the ...
As a substituent it takes the form of the prefix cytidylyl-. CMP can be phosphorylated to cytidine diphosphate by the enzyme ... Since cytidine triphosphate is generated by amination of uridine triphosphate, the main source of CMP is from RNA being ... CMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase cytosine; hence, a ribonucleoside ...
The end-product of this pathway is uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), which is then used for making ... Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and ... and is the biochemical precursor of all nitrogen-containing sugars. Specifically in humans, glucosamine-6-phosphate is ...
... a precursor step for the synthesis of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc). Impaired function of PGM3 is ... Mutations in the sugar-binding domain leads to reduced PGM3 abundance and impairs PGM3 function and glycosylation to a higher ... It has been suggested that exogenous nondiabeotgenic sugar supplementations of GlcNAc might be used to increase UDP-GlcNAc and ... sugar-binding domain, and phosphate-binding domain. Missense and deletion mutations have been discovered within multiple of ...