The enzyme tyrosine phenol-lyase (EC 4.1.99.2) catalyzes the chemical reaction L-tyrosine + H2O ⇌ {\displaystyle \ ... and L-tyrosine phenol-lyase (deaminating). This enzyme participates in tyrosine metabolism and nitrogen metabolism. It employs ... class of carbon-carbon lyases. The systematic name of this enzyme class is L-tyrosine phenol-lyase (deaminating; pyruvate- ... Kumagai H, Yamada H, Matsui H, Ohkishi H, Ogata K (1970). "Tyrosine phenol lyase. II. Cofactor requirements". J. Biol. Chem. ...
The second utilizes enzymatic synthesis from phenolics, pyruvate, and ammonia through the use of tyrosine phenol-lyase. ... It transforms L-tyrosine into p-coumaric acid.Tyrosine is also the precursor to the pigment melanin. Tyrosine (or its precursor ... Tyrosine residues may also be modified by the addition of a sulfate group, a process known as tyrosine sulfation. Tyrosine ... tyrosine to morphine by using Carbon-14 radio-labelled tyrosine to trace the in-vivo synthetic route.Tyrosine ammonia lyase ( ...
... citramalyl-CoA lyase * *No Wikipedia article EC 4.1.99.1: tryptophanase EC 4.1.99.2: tyrosine phenol-lyase EC 4.1.99.3: ... tyrosine ammonia-lyase EC 4.3.1.24: phenylalanine ammonia-lyase EC 4.3.1.25: phenylalanine/tyrosine ammonia-lyase EC 4.3.1.26: ... tyrosine ammonia-lyase), EC 4.3.1.24 (phenylalanine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase) EC ... pectin lyase EC 4.2.2.11: guluronate-specific alginate lyase EC 4.2.2.12: xanthan lyase EC 4.2.2.13: exo-(1→4)-α-D-glucan lyase ...
Tyrosine ammonia lyase (EC 4.3.1.23, L-tyrosine ammonia-lyase, TAL or Tyrase) is an enzyme in the natural phenols biosynthesis ... phenylalanine ammonia-lyase) EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase) Louie GV, Bowman ME, Moffitt MC, Baiga TJ, ... "Discovery of a substrate selectivity switch in tyrosine ammonia-lyase, a member of the aromatic amino acid lyase family". ... Tyrosine+ammonia-lyase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) www.hhmi.org Portal: Biology v ...
... tyrosine phenol-lyase MeSH D08.811.520.232.300 - amidine-lyases MeSH D08.811.520.232.300.200 - adenylosuccinate lyase MeSH ... chondroitin lyases MeSH D08.811.520.241.700.350.500.500 - chondroitin abc lyase MeSH D08.811.520.241.700.512 - heparin lyase ... ammonia-lyases MeSH D08.811.520.232.400.200 - aspartate ammonia-lyase MeSH D08.811.520.232.400.350 - ethanolamine ammonia-lyase ... receptor protein-tyrosine kinases MeSH D08.811.913.696.620.682.725.400.020 - fms-like tyrosine kinase 3 MeSH D08.811.913.696. ...
It is also produced from L-tyrosine by the action of tyrosine ammonia lyase (TAL). → T A L {\displaystyle {\xrightarrow {\ ... Vinyl phenol reductase then catalyzes the reduction of 4-vinylphenol to 4-ethylphenol. Coumaric acid is sometimes added to ...
L-tyrosine is converted to p-coumaric acid by the enzyme tyrosine ammonia lyase (TAL). From here, p-coumaric acid is converted ... Phenols, Allyl compounds, O-methylated natural phenols, O-methylated phenylpropanoids). ... Like many other anesthetic agents, these 2-alkyl(oxy)phenols act as positive allosteric modulators of the GABAA receptor. ... The biosynthesis of eugenol begins with the amino acid tyrosine. ... these findings led to the development of 2-substituted phenol ...
This was indeed proven when isotopically labeled 4-HBA was observed to be incorporated into the phenol ring of PBP at >80%. ... a chorismate lyase (CL), to yield 4-HBA. 4-HBA is then di-halogenated by the flavin-dependent halogenase, Bmp5 (Hal), to yield ... proline in addition to tyrosine, histidine, ornithine, glycine, potassium bromide (KBr), and PBP. From this feeding experiment ... In 1994, a feeding experiment study conducted on Alteromonas luteoviolaceus demonstrated that the phenol ring of PBP is derived ...
... tyrosine ammonia-lyase, L-tyrosine ammonia-lyase, phenylalanine ammonium-lyase, PAL, and L-phenylalanine ammonia-lyase. ... "Mechanisms of inhibition of phenylalanine ammonia-lyase by phenol inhibitors and phenol/glycine synergistic inhibitors". ... phenylalanine ammonia-lyases), EC 4.3.1.25 (tyrosine ammonia-lyases), and EC 4.3.1.26 (phenylalanine/tyrosine ammonia-lyases). ... Phenylalanine ammonia lyase is specific for L-phenylalanine, and to a lesser extent, L-tyrosine. The reaction catalyzed by PAL ...
... is also very efficient at degrading alginate, expressing as many as five separate alginate lyases and ... Some strains are specialised in their associations with prochlorococcus species through enhanced phenol degradation, while ... and tyrosine during growth. An ATPase-independent mechanism is involved in the transport of the siderophores which scavenge ...
... phenylalanine ammonia lyase (PAL), E2, tyrosine ammonia lyase (TAL), E3, cinnamate 4-hydroxylase, E4, 4-coumaroyl: CoA-ligase, ... "Database on polyphenol content in foods, v. 3.6". Phenol Explorer. 2016. Hammerstone JF, Lazarus SA, Schmitz HH (August 2000 ... HSCoA, Coenzyme A. L-Tyr, L-tyrosine, L-Phe, L-phenylalanine. Flavan-3-ols are abundant in teas derived from the tea plant ...
Tyrosine), but is both Thr (Theronine) and Trp (Tryptophan). †Note that this initialism uses single letters for each amino acid ... Lyases 5 - Isomerases 6 - Ligases 7 - Translocases LMNOP: Lasix (furosemide) Morphine (diamorphine) Nitrates Oxygen (sit ... phenol, propranolol Benzodiazepine withdrawal, botanicals Ethanol withdrawal Lithium, lidocaine Lindane, lead ABCDEFGHI: Acute ...
... phenol, triclosan, and paraben. GFP is great as a reporter protein because it has no effect on the host when introduced to the ... known as a lyase. Jellyfish- and coral-derived GFP-like proteins require oxygen and produce a stoichiometric amount of hydrogen ... is accomplished by the T203Y mutation and is due to π-electron stacking interactions between the substituted tyrosine residue ... is nonfluorescent in the absence of the properly folded GFP scaffold and exists mainly in the un-ionized phenol form in wtGFP. ...
3-methyl-L-tyrosine peroxygenase * EC 1.11.2.6: L-tyrosine peroxygenase * *No Wikipedia article EC 1.12.1.1: Now EC 1.12.7.2, ... chlorite O2-lyase EC 1.13.11.50: acetylacetone-cleaving enzyme EC 1.13.11.51: 9-cis-epoxycarotenoid dioxygenase EC 1.13.11.52: ... phenol 2-monooxygenase EC 1.14.13.8: flavin-containing monooxygenase EC 1.14.13.9: kynurenine 3-monooxygenase EC 1.14.13.10: 2, ... L-tyrosine isonitrile desaturase * EC 1.14.20.10: L-tyrosine isonitrile desaturase/decarboxylase * EC 1.14.20.11: 3-[(Z)-2- ...
... receptor protein-tyrosine kinase EC 2.7.10.2: non-specific protein-tyrosine kinase EC 2.7.11.1: non-specific serine/threonine ... phenol β-glucosyltransferase EC 2.4.1.36: α,α-trehalose-phosphate synthase (GDP-forming) EC 2.4.1.37: fucosylgalactoside 3-α- ... lyase) S-acetyltransferase EC 2.3.1.50: serine C-palmitoyltransferase EC 2.3.1.51: 1-acylglycerol-3-phosphate O-acyltransferase ... tyrosine 3-monooxygenase] kinase EC 2.7.1.125: Now EC 2.7.11.14, rhodopsin kinase EC 2.7.1.126: Now EC 2.7.11.15, β-adrenergic- ...
L-tyrosine is converted to 4-coumaric acid by tyrosine ammonia lyase, which is converted to caffeic acid by Sam5, which is then ... Phenol antioxidants, O-methylated hydroxycinnamic acids, Bitter-masking compounds, Vinylogous carboxylic acids). ... "Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain". Microbial Cell Factories ...