... 's chief method of activity is as a tyrosine kinase inhibitor. Tyrosine kinases are less widespread than their ser/thr ... "Genistein Inhibits Cell Growth by Modulating Various Mitogen-Activated Protein Kinases and AKT in Cervical Cancer Cells". ... The main known activity of genistein is tyrosine kinase inhibitor, mostly of epidermal growth factor receptor (EGFR). Tyrosine ... inhibition of several tyrosine kinases inhibition of topoisomerase inhibition of AAAD direct antioxidation with some pro ...

Navas TA, Baldwin DT, Stewart TA (November 1999). "RIP2 is a Raf1-activated mitogen-activated protein kinase kinase". The ... Yokoo T, Kitamura M (May 1996). "Antioxidant PDTC induces stromelysin expression in mesangial cells via a tyrosine kinase-AP-1 ... "Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane ... Manicassamy S, Gupta S, Huang Z, Sun Z (June 2006). "Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up ...

Early research has shown potential for using the c-kit tyrosine kinase blocking properties of imatinib to treat plexiform ... "Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells". Molecular ... This drug is a Farnesyltransferase inhibitor which inhibits the Ras kinase in a post translational modification step before the ... The mast cells then secrete mitogens or survival factors that alter the developing tumor microenvironment and result in ...

This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related ... of the lymphoid system in B cell subsets enhances B cell antigen receptor signaling through mitogen-activated protein kinase ... and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen ... Liu SK, McGlade CJ (Dec 1998). "Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine- ...

... translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR ... Guasch G, Delaval B, Arnoulet C, Xie MJ, Xerri L, Sainty D, Birnbaum D, Pébusque MJ (January 2004). "FOP-FGFR1 tyrosine kinase ... "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity ...

A mechanism for negative signaling by the Lyn tyrosine kinase". The Journal of Biological Chemistry. 277 (35): 31703-31714. doi ... impaired activation of the mitogen-activated protein (MAP) kinases p38, JNK, and somewhat inhibited ERK activation upon (BCR) ... Evidence suggests that BLNK is phosphorylated by the tyrosine-protein kinase Syk after B cell receptor activation. ... October 1999). "Identification of the SH2 domain binding protein of Bruton's tyrosine kinase as BLNK--functional significance ...

Kamakura S, Moriguchi T, Nishida E (1999). "Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. ... Janknecht R, Hunter T (1997). "Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen- ... a novel mitogen-activated protein kinase with distinct properties". J. Biol. Chem. 272 (31): 19509-17. doi:10.1074/jbc.272.31. ... Janknecht R, Hunter T (1997). "Convergence of MAP kinase pathways on the ternary complex factor Sap-1a". EMBO J. 16 (7): 1620-7 ...

Li Y, Kuwahara H, Ren J, Wen G, Kufe D (March 2001). "The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 ... Stambolic V, Woodgett JR (November 1994). "Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 ... May 2002). "Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta ... "A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent ...

"MAP2K1 mitogen-activated protein kinase kinase 1 [Homo sapiens (human)] - Gene - NCBI". Lones MA, Raphael M, McCarthy K, ... Bruon's tyrosine kinase inhibitor, ibrutinib, to block the B-cell maturating actions of this kianase; 4) BCL inhibitor ... Bruton's tyrosine kinase inhibitor produced overall and complete response rates of 38% and 18%, respectively; the Bcl inhibitor ... Phosphoinositide 3-kinase inhibitors such as copanlisib, duvelisib, and idelalisib which block the phosphoinositide 3-kinase ...

Baker CV, Sharpe CR, Torpey NP, Heasman J, Wylie CC (April 1995). "A Xenopus c-kit-related receptor tyrosine kinase expressed ... Fu XB, Xing F, Yang YH, Sun TZ, Guo BC (September 2003). "Activation of phosphorylating-p38 mitogen-activated protein kinase ... receptor tyrosine kinase". Blood. 90 (1): 111-25. PMID 9207445. Pfeilstöcker M, Karlic H, Paukovits J, et al. (April 1999). "In ... 2005). "Leukemia inhibitory factor as an anti-apoptotic mitogen for pluripotent mouse embryonic stem cells in a serum-free ...

FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase". ... Haystead TA, Haystead CM, Hu C, Lin TA, Lawrence JC (1994). "Phosphorylation of PHAS-I by mitogen-activated protein (MAP) ... kinase. Identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes". J. Biol. ... a novel protein kinase regulated by the p38 MAP kinase". EMBO J. 17 (12): 3372-3384. doi:10.1093/emboj/17.12.3372. PMC 1170675 ...

... receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation". ... "Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine ... factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase- ... "Stimulation of leukemia inhibitory factor receptor degradation by extracellular signal-regulated kinase". The Journal of ...

The authors found that KOR activates p38, a member of the mitogen-activated protein kinase (MAPK) family, through ... The N-terminal tyrosine of dynorphin A is necessary to activate opioid receptors such as KOR, but is unnecessary in binding to ... causes an increase in phosphorylated p38 mitogen-activated protein kinase (MAPK) in microglia in the dorsal horn of the spinal ... "Prostaglandin E2 release evoked by intrathecal dynorphin is dependent on spinal p38 mitogen activated protein kinase". ...

Paruch S, El-Benna J, Djerdjouri B, Marullo S, Périanin A (January 2006). "A role of p44/42 mitogen-activated protein kinases ... The ability of PLD to suppress apoptosis in cells with elevated tyrosine kinase activity makes it a candidate oncogene in ... Balboa MA, Firestein BL, Godson C, Bell KS, Insel PA (April 1994). "Protein kinase C alpha mediates phospholipase D activation ... Mammalian PLD directly interacts with kinases like PKC, ERK, TYK and controls the signalling indicating that PLD is activated ...

"Tumorigenesis Suppressor Pdcd4 Down-Regulates Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 Expression to Suppress ... "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nature Biotechnology. 23 (1): 94-101. doi:10.1038/ ... "Robust Phosphoproteomic Profiling of Tyrosine Phosphorylation Sites from Human T Cells Using Immobilized Metal Affinity ...

... inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain". Genes Cells. ... "The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced ... inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain". Genes Cells. ... The SOCS3 protein can bind to JAK2 kinase, and inhibits the activity of JAK2 kinase. SOCS3 has been shown to interact with: ...

Microglia interact with β-amyloid plaques through cell surface receptors that are linked to tyrosine kinase based signaling ... have shown that they are activated by diverse stimuli but they are dependent on activation of mitogen-activated protein kinase ... and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase ... are upregulated following injury and the increase in purinergic signaling activates p38-mitogen-activated protein kinase (p38 ...

... the JAK kinases (a family of protein tyrosine kinases), and the PIP3-dependent kinase cascade were discovered. Kinases are ... Garrington TP, Johnson GL (April 1999). "Organization and regulation of mitogen-activated protein kinase signaling pathways". ... Whereas RAF and MAPK are both serine/threonine kinases, MAPKK is a tyrosine/threonine kinase. MAPK can regulate transcription ... The protein kinases make up the majority of all kinases and are widely studied. These kinases, in conjunction with phosphatases ...

Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression". European Journal of Biochemistry. ... on CB2 receptors revealed that changes in cAMP levels result in the phosphorylation of leukocyte receptor tyrosine kinase at ... "Regulation of cell motility by mitogen-activated protein kinase". The Journal of Cell Biology. 137 (2): 481-492. doi:10.1083/ ...

Buhl AM, Osawa S, Johnson GL (1995). "Mitogen-activated protein kinase activation requires two signal inputs from the human ... "Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase". Proc. Natl. Acad. Sci ... "Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2". J. Biol. Chem. 275 ( ...

... he demonstrated that focal adhesion kinases and p38 mitogen-activated protein kinases could be used as possible drug targets. ... could be stopped by inhibiting the activity of the insulin receptor tyrosine kinase, which was a new discovery. His research ... phosphatidylinositol 3-kinase and extracellular signal regulated kinases". Journal of Cellular Physiology. 193 (2): 187-198. ... Recombinant DNA Protein kinase C GLUT4 Metformin India portal Medicine portal See also "Selected bibliography" section "Faculty ...

"Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase ... the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu". The Journal of Biological Chemistry. 279 (15): 14909-16 ... "Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A". The Journal of ... Janknecht R (Feb 2003). "Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated ...

"BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3". ... BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases". Oncogene. 15 (2): 143-57. ... kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment ... ATM/ATR are kinases activated by DNA damage. Mutation of serine residues may affect localization of BRCA1 to sites of DNA ...

... factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase ... Giepmans BN, Feiken E, Gebbink MF, Moolenaar WH (2003). "Association of connexin43 with a receptor protein tyrosine phosphatase ... Cooper CD, Lampe PD (Nov 2002). "Casein kinase 1 regulates connexin-43 gap junction assembly". The Journal of Biological ...

Zhu, AJ; Haase, I; Watt, FM (1999). "Signaling via beta1 integrins and mitogen-activated protein kinase determines human ... Wnt and receptor tyrosine kinase signalling in regulating their behavior. She identified the first marker, integrin ...

ROS facilitates cancer cell survival since cell-cycle progression driven by growth factors and receptor tyrosine kinases (RTK) ... of signaling pathways involved in cell migration and invasion such as members of the mitogen activated protein kinase (MAPK) ... family - extracellular regulated kinase (ERK), c-jun NH-2 terminal kinase (JNK) and p38 MAPK. ROS can also promote migration by ... checkpoint kinase 1 (Chk 1), Chk 2; and reduced cell division cycle 25 homolog c (CDC25). A cancer cell can die in three ways: ...

... subunit kinase EC 2.7.11.24: mitogen-activated protein kinase EC 2.7.11.25: mitogen-activated protein kinase kinase kinase EC ... kinase EC 2.7.1.112: Now EC 2.7.10.2, non-specific protein-tyrosine kinase EC 2.7.1.113: deoxyguanosine kinase EC 2.7.1.114: ... dual-specificity kinase EC 2.7.12.2: mitogen-activated protein kinase kinase EC 2.7.13.1: protein-histidine pros-kinase EC 2.7. ... kinase EC 2.7.11.6: [tyrosine 3-monooxygenase] kinase EC 2.7.11.7: myosin-heavy-chain kinase EC 2.7.11.8: Fas-activated serine/ ...

"Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity". The ... Midde NM, Yuan Y, Quizon PM, Sun WL, Huang X, Zhan CG, Zhu J (March 2015). "Mutations at tyrosine 88, lysine 92 and tyrosine ... and protein kinase C (PKC) signaling. Phosphorylation by either protein kinase can result in DAT internalization (non- ... it reduces the firing rate of the postsynaptic neuron and triggers protein kinase A and protein kinase C signaling, resulting ...

... protein-tyrosine kinase - protein-tyrosine-phosphatase - proteinoid - proteomics - protirelin - proto-oncogene - proto-oncogene ... mitogen receptor - mitosis - mitotic spindle - mixture - modern evolutionary synthesis - molar volume - mole (unit) - molecular ... receptor protein-tyrosine kinase - recombinant fusion protein - recombinant interferon-gamma - recombinant protein - ... tyrosine - tyrosine 3-monooxygenase ubiquitin - urea - urea cycle - uric acid - UV/VIS spectroscopy vaccine - vacuole - valence ...

Mikels, Amanda; Minami, Yasuhiro; Nusse, Roel (2009-10-30). "Ror2 Receptor Requires Tyrosine Kinase Activity to Mediate Wnt5A ... "The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin ... involvement of the wnt/glycogen synthase kinase-3 beta pathway". Journal of Immunology. 169 (7): 3717-25. doi:10.4049/jimmunol. ...

... cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine ... "Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase". Proc. Natl. Acad. Sci. U.S.A. 94 ( ... "Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB ... Mitogen-activated protein kinase 8 (also known as JNK1) is a ubiquitous enzyme that in humans is encoded by the MAPK8 gene. The ...

Tsuda M, Tozaki-Saitoh H, Masuda T, Toyomitsu E, Tezuka T, Yamamoto T, Inoue K (January 2008). "Lyn tyrosine kinase is required ... This upregulation allows for increased activation of p38 mitogen-activated protein kinases, thereby increasing the release of ... and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase ... Royle SJ, Bobanović LK, Murrell-Lagnado RD (September 2002). "Identification of a non-canonical tyrosine-based endocytic motif ...

"Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation". Biochemical and Biophysical ... "Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic ... family of proteins that regulate growth factor-induced activation of the MAP kinase cascade. GRCh38: Ensembl release 89: ...

LDL binding to T-cadherin leads to the activation of Erk 1/2 tyrosine kinase and the nuclear translocation of NF-kappaB. T- ... Known mitogens such as platelet-derived growth factor (PDGF)-BB, epidermal growth factor (EGF) or insulin-like growth factor ( ... T-cadherin overexpression in HUVEC leads to higher phosphorylation of Phosphatidylinositol 3-kinase (PIK3) - target of Akt, and ...

... mitogen-activated protein kinase kinases MeSH D12.644.360.440.100 - map kinase kinase 1 MeSH D12.644.360.440.200 - map kinase ... cdc2 protein kinase MeSH D12.644.360.275 - eif-2 kinase MeSH D12.644.360.287 - focal adhesion protein-tyrosine kinases MeSH ... map kinase kinase kinase 1 MeSH D12.644.360.400.200 - map kinase kinase kinase 2 MeSH D12.644.360.400.300 - map kinase kinase ... kinase 3 MeSH D12.644.360.400.400 - map kinase kinase kinase 4 MeSH D12.644.360.400.500 - map kinase kinase kinase 5 MeSH ...

"Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and ... tyrosine phosphatase (TYP 1) which inactivates ERK2 and p54jnk". Oncogene. 11 (12): 2553-63. PMID 8545112. Chu Y, Solski PA, ... They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are ... Khosravi-Far R, Der CJ, Kelly K (Mar 1996). "The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have ...

The Insulin Receptor is a type of tyrosine kinase receptor, in which the binding of an agonistic ligand triggers ... This protein then begins a phosphorylation cascade, culminating in the activation of mitogen-activated protein kinase (MAPK), ... IGF-II and belongs to the large class of receptor tyrosine kinase. Metabolically, the insulin receptor plays a key role in the ... "Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family". Oncogene. 19 (25): 2895-903. doi: ...

... cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3 ... and protein kinase C (PKC). Smad7 does not have the MH1 domain. A proline-tyrosine (PY) motif presents at its linker region ... Erk-family MAP kinases, the Ca2+ /calmodulin-dependent protein kinase II (CamKII) ... Yakymovych I, Ten Dijke P, Heldin CH, Souchelnytskyi S (March 2001). "Regulation of Smad signaling by protein kinase C". FASEB ...

Zheng Q, Yin G, Yan C, Cavet M, Berk BC (March 2004). "14-3-3beta binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) ... "Entrez Gene: YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide". Ewing RM, Chu P, ... "Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1". J. Biol. Chem ... Qiu W, Zhuang S, von Lintig FC, Boss GR, Pilz RB (October 2000). "Cell type-specific regulation of B-Raf kinase by cAMP and 14- ...

... and/or 271 by mitogen-activated protein kinases, S6 kinase, protein kinase A (PKA), protein kinase C, Cdc2, and/or a Ca2+/ ... promotes its binding to proteins with SH3 domains such as Grb2 and may thereby link the enzyme's regulation to tyrosine kinase ... This chemotactic factor stimulation concurrently causes the activation of mitogen-activated protein kinases (MAPK) which in ... calmodulin-dependent protein kinase; b) moves to bind with phospholipids in the nuclear membrane and, probably, endoplasmic ...

For example, the Na⁺-K⁺ pump interacts directly with Src, a non-receptor tyrosine kinase, to form a signaling receptor complex ... signals through ouabain-triggered protein phosphorylation events include activation of the mitogen-activated protein kinase ( ... However, upon subsequent ouabain binding, the Src kinase domain is released and then activated. Based on this scenario, NaKtide ... membrane protein can also relay extracellular ouabain-binding signalling into the cell through regulation of protein tyrosine ...

Dual specificity mitogen-activated protein kinase kinase 7, also known as MAP kinase kinase 7 or MKK7, is an enzyme that in ... Once activated, MKK4 and MKK7 directly phosphorylate specific tyrosine and threonine residues located in the conserved T-P-Y ... Stress-activated protein kinase kinase 4 (SAPK kinase 4, SAPKK4) c-Jun N-terminal kinase kinase 2 (JNK kinase 2, JNKK2) Stress- ... "Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase". Proceedings of the National ...

"Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase ... Among the Ras kinase family, A-Raf has the lowest kinase activity towards MEK proteins in the Raf kinase family. Thus, it is ... Upstream of A-Raf, receptor tyrosine kinases (RTKs) are activated, leading to RAS-mediated activation of Raf kinases, including ... A-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases. Compared to the other members of this ...

YopJ, which shares an operon with YpkA, "...interferes with the mitogen-activated protein (MAP) kinase activities of c-Jun N- ... Persson C, Carballeira N, Wolf-Watz H, Fällman M (1997). "The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation ... enterocolitica promotes deactivation of macrophage mitogen-activated protein kinases extracellular signal-regulated kinase-1/2 ... terminal kinase (JNK), p38, and extracellular signal-regulated kinase", leading to macrophage apoptosis. In addition, YopJ ...

... kinase and mitogen-activated protein (MAP) kinase pathways". J. Leukoc. Biol. 78 (4): 1016-23. doi:10.1189/jlb.0105056. PMID ... 1998). "HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells ... The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling ... This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3- ...

STATs may also be tyrosine-phosphorylated directly by receptor tyrosine kinases - but since most receptors lack built-in kinase ... Secondly, a protein activated by the MAPK/ERK pathway, called MAPK (mitogen-activated protein kinase), can phosphorylate STATs ... but by other receptor-bound kinases. So, if one of the kinases (either JAK or the alternative SH2-containing kinase) cannot ... In this model, SH2 domain-containing kinases, can bind to phosphorylated tyrosines on receptors and directly phosphorylate ...

... is an orally available inhibitor of mitogen-activated protein kinase kinase (MEK), or more specifically, a MAP2K ... MEK1/2 are dual-specificity threonine/tyrosine kinases that play key roles in the activation of the RAS/RAF/MEK/ERK pathway and ... Binimetinib, uncompetitive with ATP, binds to and inhibits the activity of MEK1/2 kinase, which has been shown to regulate ... Binimetinib is a selective inhibitor of MEK, a central kinase in the tumor-promoting MAPK pathway. Inappropriate activation of ...

"Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete ... because they deactivate MAPK by dephosphorylating the Threonine and the Tyrosine residues residing in MAPKs activation site. ... Wu, J. J.; Zhang, L.; Bennett, A. M. (16 May 2005). "The Noncatalytic Amino Terminus of Mitogen-Activated Protein Kinase ... Wu, J. J.; Zhang, L.; Bennett, A. M. (16 May 2005). "The Noncatalytic Amino Terminus of Mitogen-Activated Protein Kinase ...

The phosphorylation mediates activation of tyrosine kinase SHP2. SIRP α has been shown to bind also phosphatase SHP1, adaptor ... that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion". Mol. Cell. ... 1996). "Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule". J. ... 1999). "Tyrosine phosphorylation and association of BIT with SHP-2 induced by neurotrophins". J. Neurochem. 72 (4): 1402-8. doi ...

"Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional ... Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor". Cell Stress & Chaperones. 1 (4 ... a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase ... Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor". Cell Stress & Chaperones. 1 (4 ...

Katzav S, Sutherland M, Packham G, Yi T, Weiss A (1995). "The protein tyrosine kinase ZAP-70 can associate with the SH2 domain ... Weng WK, Jarvis L, LeBien TW (1995). "Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces ... "Nuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic ... Hehner SP, Li-Weber M, Giaisi M, Dröge W, Krammer PH, Schmitz ML (April 2000). "Vav synergizes with protein kinase C theta to ...