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*  PLA2R1
Secretory phospholipase A2 receptor is an enzyme that in humans is encoded by the PLA2R1 gene. M-type phospholipase A2 receptor ... "M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy". The New England Journal of Medicine. ... "Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals". European Journal ... "Entrez Gene: PLA2R1 phospholipase A2 receptor 1, 180kDa". Beck LH, Bonegio RG, Lambeau G, Beck DM, Powell DW, Cummins TD, Klein ...
*  Membranous glomerulonephritis
One study has identified antibodies to an M-type phospholipase A2 receptor in 70% (26 of 37) cases evaluated. Other studies ... July 2, 2009). "M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephrovv pathy". The New England ...
*  Sphingomyelin
It is hydrolyzed by sphingomyelinases (sphingomyelin specific type-C phospholipases). The phosphocholine head group is released ... Children with this type rarely live beyond 18 months. Type B involves an enlarged liver and spleen, which usually occurs in the ... Of the two types involving sphingomyelinase, type A occurs in infants. It is characterized by jaundice, an enlarged liver, and ... Due to the specific types of lipids in these microdomains, lipid rafts can accumulate certain types of proteins associated with ...
*  Lecithinase
... is a type of phospholipase that acts upon lecithin. It can be produced by Clostridium perfringens, Staphylococcus ...
*  Versican
Sartipy P, Johansen B, Camejo G, Rosengren B, Bondjers G, Hurt-Camejo E (1996). "Binding of human phospholipase A2 type II to ... Sartipy P, Bondjers G, Hurt-Camejo E (1999). "Phospholipase A2 type II binds to extracellular matrix biglycan: modulation of ... The C-terminal (G3) globular domain consists of one or two Epidermal growth factor (EGF) repeats, a C-type lectin domain and ... Aspberg A, Miura R, Bourdoulous S, Shimonaka M, Heinegârd D, Schachner M, Ruoslahti E, Yamaguchi Y (1997). "The C-type lectin ...
*  PLA2G2A
1996). "Binding of human phospholipase A2 type II to proteoglycans. Differential effect of glycosaminoglycans on enzyme ... Phospholipase A2, membrane associated is an enzyme that in humans is encoded by the PLA2G2A gene. Phospholipase A2 GRCh38: ... 1995). "The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal ... "Entrez Gene: PLA2G2A Phospholipase A2, group IIA (platelets, synovial fluid)". Kramer RM, Johansen B, Hession C, Pepinsky RB ( ...
*  ENPP7
... is the only enzyme that has a type of phospholipase C activity against sphingomyelin. ENPP7 is the key enzyme in the gut ... ENPP7 is a new name for an old enzyme whose activity was originally identified in 1969 by Nilsson as a type of sphingomyelinase ... Liu F, Cheng Y, Wu J, Tauschel HD, Duan RD (April 2006). "Ursodeoxycholic acid differentially affects three types of ... The activity of ENPP7 depends specifically on two types of primary bile salts, taurocholate (TC) and taurochenodeoxycholate ( ...
*  Snake venom
For instance, Phospholipases type A2 (PLA2s) from the Tunisian vipers Cerastes cerastes and Macrovipera lebetina has been found ... Phospholipases: Phospholipase is an enzyme that transforms the phospholipid molecule into a lysophospholipid (soap) ==> the new ... Phospholipase A2 causes hemolysis by lysing the phospholipid cell membranes of red blood cells. Amino acid oxidases and ... There are numerous other types of toxin which both elapids and viperids may carry. The beginning of a new impulse: A) An ...
*  Varespladib methyl
"Circulating Levels of Secretory Type II Phospholipase A2 Predict Coronary Events in Patients with Coronary Artery Disease". ... Varespladib methyl (also known as A-002, formerly LY333013 and S-3013) is a secretory phospholipase A2 (sPLA2) inhibitor ... a secretory phospholipase A2 inhibitor, reduces atherosclerosis and aneurysm formation in ApoE-/- mice". Journal of ... "Circulating Secretory Phospholipase A2 Activity Predicts Recurrent Events in Patients With Severe Acute Coronary Syndromes". ...
*  Thromboregulation
... receptor type α, phospholipase Cβ3, and IP3 receptors. Signalization in platelets is very sensitive in cAMP levels. Nitric ... Both receptors mediate phospholipase C stimulation causing an increase of intracellular levels of inositol 1,4,5-triphosphate ... This kinase inhibits Gαq-phospholipase C-inositol 1,4,5-triphosphate signaling and the mobilization of calcium inside the cell ...
*  CD90
Thy-1, like many other GPI anchored proteins can be shed by special types of Phospholipase C e.g. PI-PLC (phosphatidyl-Inositol ... Crosslinking anti-Thy-1 Ab can promote neurite outgrowth which is dependent on G{alpha}i and L- and N-type calcium channel ... In this regard it has yet another historic association: Thy1 happens to be the first glycoprotein in which cell type ... learning from other mice which foods are safe to eat as compared to wild-type mice). This failure can be rescued by the ...
*  PLA2G1B
Sartipy P, Bondjers G, Hurt-Camejo E (1999). "Phospholipase A2 type II binds to extracellular matrix biglycan: modulation of ... Phospholipase A2, group 1B is an enzyme that in humans is encoded by the PLA2G1B gene. Phospholipase A2 (EC 3.1.1.4) catalyzes ... "Diversity of group types, regulation, and function of phospholipase A2". J Biol Chem. 269 (18): 13057-60. PMID 8175726. "Entrez ... 1995). "Phospholipase A2 gene expression and activity in histologically normal ileal mucosa and in Crohn's ileitis". Gut. 37 (3 ...
*  Phospholipase A-2-activating protein
"Bimodal regulatory effect of melittin and phospholipase A2-activating protein on human type II secretory phospholipase A2". ... Phospholipase A-2-activating protein is an enzyme that in humans is encoded by the PLAA gene. GRCh38: Ensembl release 89: ... "Entrez Gene: PLAA phospholipase A2-activating protein". Clark MA, Ozgür LE, Conway TM, et al. (1991). "Cloning of a ... Ruiz A, Nadal M, Puig S, Estivill X (1999). "Cloning of the human phospholipase A2 activating protein (hPLAP) gene on the ...
*  Phospholipase A2
Additional types of phospholipases include phospholipase A1, phospholipase B, phospholipase C, and phospholipase D. ... There are atypical members of the phospholipase A2 family, such as PLA2G12B, that have no phospholipase activity with typical ... "Diversity of group types, regulation, and function of phospholipase A2". The Journal of Biological Chemistry. 269 (18): 13057- ... "Localization of structural elements of bee venom phospholipase A2 involved in N-type receptor binding and neurotoxicity". The ...
*  PLA2G2D
"Increased gene expression of novel cytosolic and secretory phospholipase A(2) types in human airway epithelial cells induced by ... "Interferon gamma-induced gene expression of the novel secretory phospholipase A2 type IID in human monocyte-derived macrophages ... Group IID secretory phospholipase A2 is an enzyme that in humans is encoded by the PLA2G2D gene. GRCh38: Ensembl release 89: ... "Entrez Gene: PLA2G2D phospholipase A2, group IID". Schröder HC, Perovic S, Kavsan V, et al. (1998). "Mechanisms of prionSc- and ...
*  PRDX6
1997). "Identification of a human cDNA clone for lysosomal type Ca2+-independent phospholipase A2 and properties of the ... Occurrence of phospholipase A1 and A2 in human decidua". Prostaglandins. 9 (5): 667-73. doi:10.1016/0090-6980(75)90106-9. PMID ... Yeats DA, Bakhle YS (1989). "Phospholipases A2 and C of human lung; subcellular distribution and substrate selectivity". ... 2003). "A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances ...
*  Lipidomics
"Quantitative profiling of polar glycerolipid species from organs of wild-type Arabidopsis and a phospholipase Dalpha1 knockout ... In practice, not all possible permutations are detected experimentally, due to chain preferences depending on the cell type and ... may be broadly defined as hydrophobic or amphipathic small molecules that originate entirely or in part from two distinct types ...
*  PLA2G4A
"Diversity of group types, regulation, and function of phospholipase A2". Journal of Biological Chemistry. 269 (18): 13057-13060 ... Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. This gene encodes a member of the ... "Entrez Gene: PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)". Sheridan AM, Force T, Yoon HJ, O'Leary E, ... 1995). "Cytosolic phospholipase A2 gene in human and rat: chromosomal localization and polymorphic markers". Genomics. 26 (1): ...
*  Toxicocalamus
Type-I phospholipase A2 (PLA2) and snake venom metalloproteinase (SVMP), while T. buergersi possesses long venom glands than ...
*  GNAQ
Petit A, Geoffroy P, Bélisle S (1997). "Expression of angiotensin II type-I receptor and phospholipase C-linked G alpha q/11 ... G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C- ...
*  Epoxydocosapentaenoic acid
... from the sn-2 position of their membrane-bound cellular phospholipid pools through the action of a Phospholipase A2-type enzyme ... The EDPs are commonly made by the stimulation of specific cell types by the same mechanisms which produce EETs (see ... Cell types that express certain cytochrome P450 (CYP) epoxygenases metabolize polyunsaturated fatty acid's (PUFAs) by ...
*  Lysophospholipid receptor
LPLs are usually the result of phospholipase A-type enzymatic activity on regular phospholipids such as phosphatidylcholine or ... Depending on which ligand, receptor, and cell type is involved, the activated receptor can have a range of effects on the cell ...
*  Epoxyeicosatrienoic acid
... arachidonic acid to be released from the sn-2 position of cellular phospholipids through the action of Phospholipase A2-type ... the studies suggest that the EETs have beneficial effects in Type I diabetes as well as Type II diabetes. These interventions ... They are one type of Endothelium-Derived Hyperpolarizing Factor, i.e. a substance and/or electrical signal synthesized or ... The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of ...
*  PLA2G12A
2001). "A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells". J. Biol. Chem. 276 (21): 18321-6 ... Group XIIA secretory phospholipase A2 is an enzyme that in humans is encoded by the PLA2G12A gene. GRCh38: Ensembl release 89: ... "Entrez Gene: PLA2G12A phospholipase A2, group XIIA". Schröder HC, Perovic S, Kavsan V, et al. (1998). "Mechanisms of prionSc- ... 2003). "Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII)". J. Biol ...
*  Lipase
Several other types of lipase activities exist in nature, such as phospholipases and sphingomyelinases, however these are ... "The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity". ... Phospholipases A2 UMich Orientation of Proteins in Membranes families/superfamily-29 - Outer membrane phospholipase A UMich ... Alpha toxin Lysosomal acid lipase deficiency Peripheral membrane proteins Phospholipase A Phospholipase C Triglyceride lipase ...
*  Brain ischemia
There are two types of ischemia: focal ischemia, which is confined to a specific region of the brain; and global ischemia, ... focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase ... It is a sub-type of stroke along with subarachnoid hemorrhage and intracerebral hemorrhage. Ischemia leads to alterations in ... Baldwin, Robert C. (2005). "Is vascular depression a distinct sub-type of depressive disorder? A review of causal evidence". ...