Vestergaard C, Johansen C, Otkjaer K, Deleuran M, Iversen L (January 2005). "Tumor necrosis factor-alpha-induced CTACK/CCL27 ( ... February 2005). "Induction of cytokine (interleukin-1alpha and tumor necrosis factor-alpha) and chemokine (CCL20, CCL27, and ... Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M (September 2004). "TARC augments TNF-alpha-induced CTACK ... November 1999). "Molecular cloning of a novel CC chemokine, interleukin-11 receptor alpha-locus chemokine (ILC), which is ...
... processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death ... 2002). "DBC2, a candidate for a tumor suppressor gene involved in breast cancer". Proc. Natl. Acad. Sci. U.S.A. 99 (21): 13647- ... 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97 ... Trauernicht AM, Kim SJ, Kim NH, Boyer TG (2007). "Modulation of estrogen receptor alpha protein level and survival function by ...
Endothelial zinc finger protein induced by tumor necrosis factor alpha is a protein that in humans is encoded by the ZNF71 gene ... "A novel zinc finger protein mRNA in human umbilical vein endothelial cells is profoundly induced by tumor necrosis factor alpha ...
"Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer ... "A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome". Molecular Autism. 5 (1): ...
NGR-hTNF is a recombinant protein derived from the fusion between peptide CNGRCG and human tumor necrosis factor alpha (TNFα). ... Curnis F, Sacchi A, Borgna L, Magni F, Gasparri A, Corti A (2000), Enhancement of tumor necrosis factor alpha antitumor ... NGR-hTNF is an experimental antitumor drug designed to act on tumor blood vessels. It is currently undergoing Phase III ... NGR-hTNF is also being investigated, alone or in combination with chemotherapy, on four different solid tumors in four other ...
"Reversible glutathiolation of caspase-3 by glutaredoxin as a novel redox signaling mechanism in tumor necrosis factor-alpha- ... reactivates the DNA-binding activity of oxidation-inactivated nuclear factor I." J. Biol. Chem. 273 (1): 392-7. doi:10.1074/jbc ...
"MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression ... Dermal and subcutaneous tumors". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Elsevier. pp. 593-594. ISBN ... Vascular tumors". Weedon's Skin Pathology Essentials (2nd ed.). Elsevier. p. 690. ISBN 978-0-7020-6830-0. Stockman, David L. ( ... They are a harmless benign tumour, containing an abnormal proliferation of blood vessels, and have no relationship to cancer. ...
Natalizumab may be appropriate in patients who do not respond to medications that block tumor necrosis factor-alpha, such as ... is a mouse-human chimeric antibody that targets tumor necrosis factor alpha (TNFα), a cytokine in the inflammatory response. It ... Adalimumab, like infliximab, is an antibody that targets tumor necrosis factor. It has been shown to reduce the signs and ... "Human Anti-Tumor Necrosis Factor Monoclonal Antibody (Adalimumab) in Crohn's Disease: The CLASSIC-I Trial". Gastroenterology. ...
These gene candidates include certain variations in tumor necrosis factor-alpha (TNF-alpha), IL-1 alpha, and CYP1A1 genes, ... The brain tumor risk with cyproterone acetate is due to its strong progestogenic actions and is not related to antiandrogenic ... Another common factor is the excessive growth of the bacterium Cutibacterium acnes, which is present on the skin. Treatments ... Age is one factor that may help distinguish between these disorders. Skin disorders such as perioral dermatitis and keratosis ...
Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA ... LT-alpha was known as lymphotoxin. As years progressed, its name was changed to tumor necrosis factor-beta (TNF-β). Later ... "Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell ... "The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse ...
These keratinocytes exhibit the capacity to release TNF-α (tumor necrosis factor - alpha) that stop the growth of the tumor by ... Evidence for partial involvement of tumor necrosis factor alpha in the formation of sunburn cells". The Society for ... "An endotoxin-induced serum factor that causes necrosis of tumors". Proc Natl Acad Sci USA. 72 (9): 3666-3670. Bibcode:1975PNAS ... Kinetic of "fast" erythema is much faster by the time of development of UV erythema caused by necrosis of UV damaged ...
... is one of two membrane receptors that binds tumor necrosis factor-alpha (TNFα). Like its counterpart, tumor necrosis factor ... Tumor necrosis factor receptor 2 (TNFR2), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) and ... tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B ... Sheng Y, Li F, Qin Z (2018). "TNF Receptor 2 Makes Tumor Necrosis Factor a Friend of Tumors". Frontiers in Immunology. 9: 1170 ...
... regulation by interleukin-1beta and tumour necrosis factor-alpha". Inflamm. Res. 55 (11): 483-90. doi:10.1007/s00011-006-6036-8 ... 2005). "NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into ...
Abnormal production of the tumor necrosis factor alpha and clinical efficacy of the TNF Inhibitor Etanercept in a patient with ... Treatments directed at tumor necrosis factor (TNF) (infliximab, etanercept) and interleukin-1 (anakinra) have shown a good ...
After TCR binding and activation, MAIT cells secrete several cytokines, including tumor necrosis factor alpha (TNF-α), IFN-γ, ... alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain". The Journal of ... MAIT cells constitute a subset of αβ T lymphocytes characterized by a semi-invariant T cell receptor alpha (TCRα) chain. The ... growth factors (GM-CSF, M-CSF, PDGFB, LIF) as well as angiogenic genes (HIF1A, VEGFB). This expression profile was first shown ...
... such as tumor necrosis factor-alpha (TNFα), interleukins 1 and 6 and corticotropin-releasing hormone (CRH) influence appetite ... Other factors also have been shown to effect long-term hunger and food intake regulation including insulin. In addition, the ... Lowe, M. R. (1993). "The effects of dieting on eating and behavior: A three-factor model" (PDF). Psychological Bulletin. 114 (1 ... and psychological factors. One method that the brain uses to evaluate the contents of the gut is through vagal nerve fibers ...
This in turn activates the transcription of pro-inflammatory cytokines and tumor necrosis factor-alpha (TNFα), with concurrent ... Development of mature Kupffer cells is regulated by numerous growth factors, with macrophage colony-stimulating factor (CSF1) ... M1-polarized Kupffer cells produce a large amount of pro-inflammatory cytokines like TNF-alpha. On the other hand, M2-polarized ... The macrophages in the liver activate and release both IL-1 and TNF-alpha. In turn, this activates leukocytes and sinusoidal ...
... a high affinity for phosphatidic acid and cardiolipin and can be induced by interferon gamma and tumor necrosis factor alpha. ... These trypanolytic factors have been identified as two serum complexes designated trypanolytic factors (TLF-1 and −2) both of ... Other factors involved in resistance appear to be a change in the cysteine protease activity and TbHpHbR inactivation due to a ... T. b. brucei is not infective to humans due to its susceptibility to lysis by trypanosome lytic factor-1 (TLF-1). However, it ...
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for ... 2002). "Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis ... a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated ... The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha ...
... interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to ... "Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein ... OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection. Model organisms have been used in the study ... and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein ...
"Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating ...
The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha-induced ... "Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death". J. ... MAPK8 has been shown to interact with: Activating transcription factor 2, C-jun, CRK, DUSP10, DUSP1, DUSP22, GSTP1, IRS1, ITCH ... This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early ...
The IAPP promoter is also activated by stimuli which do not affect insulin, such as tumor necrosis factor alpha and fatty acids ... In particular, the impaired processing of proIAPP that occurs at the N-terminal cleavage site is a key factor in the initiation ... In summary, impaired N-terminal processing of proIAPP is an important factor initiating amyloid formation and β-cell death. ... The terminal glycine amino acid that results from this cleavage allows the enzyme peptidylglycine alpha-amidating monooxygenase ...
"Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B ... a partial transcript map and 15 new repeat polymorphisms in a tumour-suppressor region". Eur. J. Hum. Genet. 9 (2): 121-9. doi: ... "Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked ...
... tumor necrosis factor-alpha and receptor activator of nuclear factor kappa ligand are elevated in hypertrophic gastric mucosa ... Wang, Wei; Li, Ning; Speaker, Stan (2010-08-05), "External Factors Affecting Protein Aggregation", Aggregation of Therapeutic ... by targeting the CD4 receptor on T cells and stimulating the production of cytokines and chemokines that can promote tumor cell ...
... tumor necrosis factor alpha, and C-reactive protein. Plants store starch in tightly packed granules, consisting of layers of ... Muir, J. G.; O'Dea, K. (1992). "Measurement of resistant starch: factors affecting the amount of starch escaping digestion in ... was found to increase the amount of resistant starch by a factor of 2.8. High amylose varieties of corn, wheat, barley, potato ...
Endothelial cells do not express TF except when they are exposed to inflammatory molecules such as tumor necrosis factor-alpha ... the interface between factor Xa and tissue factor in the quaternary complex tissue factor-factor VIIa-factor Xa-tissue factor ... Tissue factor has been shown to interact with Factor VII. Tissue factor Blood plasma after the addition of tissue factor ... Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in ...
"Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine ... as a single signal or by tumor necrosis factor (TNF) along with a second signal. On the other hand, transforming growth factor- ... the L-arginine-dependent killing mechanism in IFN-gamma-stimulated macrophages by induction of tumor necrosis factor-alpha". ... The research emerged in 1980 when NO was first known as the 'endothelium-derived relaxing factor' (EDRF). The identity of EDRF ...
"Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine ... as a single signal or by tumor necrosis factor (TNF) along with a second signal. On the other hand, transforming growth factor- ... the L-arginine-dependent killing mechanism in IFN-gamma-stimulated macrophages by induction of tumor necrosis factor-alpha". ... "Abiotic factor" Archived June 8, 2013, at the Wayback Machine. Encyclopedia of Earth. eds Emily Monosson and C. Cleveland. ...
... tumor necrosis factor alpha, and parathyroid hormone. Bishop, M.L.; Fody, E.P.; Schoeff, L.E. (2010). Clinical Chemistry: ... These include acute and chronic kidney failure, acute and chronic glomerulonephritis, tubular necrosis, and other kidney ...