Tryptophan-tRNA ligase
In enzymology, a tryptophan-tRNA ligase (EC 6.1.1.2) is an enzyme that catalyzes the chemical reaction ATP + L-tryptophan + ... tRNATrp ligase (AMP-forming). Other names in common use include tryptophanyl-tRNA synthetase, L-tryptophan-tRNATrp ligase (AMP- ... tryptophan translase, and TrpRS. This enzyme participates in tryptophan metabolism and aminoacyl-trna biosynthesis. As of late ... This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related ...
List of EC numbers (EC 6)
... tyrosine-tRNA ligase EC 6.1.1.2: tryptophan-tRNA ligase EC 6.1.1.3: threonine-tRNA ligase EC 6.1.1.4: leucine-tRNA ligase EC ... valine-tRNA ligase EC 6.1.1.10: methionine-tRNA ligase EC 6.1.1.11: serine-tRNA ligase EC 6.1.1.12: aspartate-tRNA ligase EC ... glycine-tRNA ligase EC 6.1.1.15: proline-tRNA ligase EC 6.1.1.16: cysteine-tRNA ligase EC 6.1.1.17: glutamate-tRNA ligase EC ... glutamine-tRNA ligase EC 6.1.1.19: arginine-tRNA ligase EC 6.1.1.20: phenylalanine-tRNA ligase EC 6.1.1.21: histidine-tRNA ...
Phenylalanine-tRNA ligase
... tyrosine and tryptophan biosynthesis and aminoacyl-tRNA biosynthesis. Phenylalanine-tRNA synthetase (PheRS) is known to be ... phenylalanyl-tRNA ligase, phenylalanyl-transfer RNA ligase, L-phenylalanyl-tRNA synthetase, and phenylalanine translase. This ... This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related ... In enzymology, a phenylalanine-tRNA ligase (EC 6.1.1.20) is an enzyme that catalyzes the chemical reaction ATP + L- ...
List of MeSH codes (D08)
... serine-trna ligase MeSH D08.811.464.263.200.800 - threonine-tRNA ligase MeSH D08.811.464.263.200.850 - tryptophan-tRNA ligase ... alanine-tRNA ligase MeSH D08.811.464.263.200.100 - arginine-tRNA ligase MeSH D08.811.464.263.200.150 - aspartate-tRNA ligase ... glutamate-trna ligase MeSH D08.811.464.263.200.350 - glycine-trna ligase MeSH D08.811.464.263.200.400 - histidine-trna ligase ... isoleucine-trna ligase MeSH D08.811.464.263.200.500 - leucine-trna ligase MeSH D08.811.464.263.200.550 - lysine-trna ligase ...
Radical SAM
... tryptophan 2-C-methyltransferase (amino acid modification - antibiotic biosynthesis) TYW1 - 4-demethylwyosine synthase (tRNA ... For example, a ligase combines two molecules to form a new bond. Representative enzymes will be mentioned for each class. ... Mutations in human wybutosine-tRNA modifying enzyme Tyw1 promotes retrovirus infection. Alterations in human tRNA-modifying ... tRNA methylthiotransferase (tRNA modification) MoaA - GTP 3',8-cyclase (cofactor biosynthesis - molybdopterin) MqnC - ...
List of biomolecules
... tRNA) Triacsin C Thyroid-stimulating hormone (TSH) Thyrotropin-releasing hormone (TRH) Thyroxine (T4) Tocopherol (Vitamin E) ... Lactase Lactic acid Lactose Lanolin Lauric acid Lectin Leptin Leptomycin B Leucine Leukotriene Ligase Lignin Limonene Linalool ... Topoisomerase Triiodothyronine (T3) Transmembrane receptor Trichostatin A Trophic hormone Trypsin Tryptophan Tubulin ... Dextran Dextrin Dicer Dihydrotestosterone DNA DNA polymerase DNA ligase Dopamine Endonuclease Enzyme Ephedrine Epinephrine - ...
N-end rule
This study revealed that Phenylalanine and Tryptophan bind specifically to ClpS1, making them prime candidates for N-degrons in ... In eukaryotic cells, these N-terminal residues are recognized and targeted by ubiquitin ligases, mediating ubiquitination ... destabilising residues are modified by the attachment of a Primary destabilising residue by the enzyme leucyl/phenylalanyl-tRNA ... and tryptophan, have short half-lives of around 2-minutes and are rapidly degraded. These residues (when located at the N- ...
RNA editing
Transfer RNA or tRNA is the most abundantly modified type of RNA. Modifications in tRNA play crucial roles in maintaining ... After editing has made mRNA complementary to gRNA, an RNA ligase rejoins the ends of the edited mRNA transcript. As a ... The latter changes were also later seen alongside non-classic U-to-C alterations in brain cell TPH2 (tryptophan hydroxylase 2) ... Reichle VF, Weber V, Kellner S (December 2018). "NAIL-MS in E. coli Determines the Source and Fate of Methylation in tRNA". ...
Chromosome 21
... ligase) HMGN1: encoding non-histone chromosomal protein HMG-14 HSPA13: encoding heat shock 70 kDa protein 13 ICOSLG: encoding ... encoding tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 ZBTB21: encoding zinc finger and BTB domain- ... encoding periodic tryptophan protein 2 homolog RBM11: encoding protein splicing regulator RBM11 RIPK4: encoding enzyme receptor ... "genetype trna"[Properties] OR "genetype scrna"[Properties] OR "genetype snrna"[Properties] OR "genetype snorna"[Properties]) ...
Mitochondrion
Mitochondrial tRNA genes have different sequences from the nuclear tRNAs, but lookalikes of mitochondrial tRNAs have been found ... In higher plants, it was thought that CGG encoded for tryptophan and not arginine; however, the codon in the processed RNA was ... kynurenine hydroxylase and fatty acid Co-A ligase. Disruption of the outer membrane permits proteins in the intermembrane space ... It encodes 37 genes: 13 for subunits of respiratory complexes I, III, IV and V, 22 for mitochondrial tRNA (for the 20 standard ...
List of EC numbers (EC 4)
... tryptophan synthase EC 4.2.1.21: Now EC 4.2.1.22 cystathionine β-synthase EC 4.2.1.22: cystathionine β-synthase EC 4.2.1.23: ... tRNA-intron lyase EC 4.6.1.17: cyclic pyranopterin monophosphate synthase * EC 4.6.1.18: pancreatic ribonuclease * EC 4.6.1.19 ... heme ligase EC 4.99.1.9:: coproporphyrin ferrochelatase * EC 4.99.1.10: magnesium dechelatase * EC 4.99.1.11: sirohydrochlorin ... L-tryptophan ammonia lyase * EC 4.3.1.32: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase * *No Wikipedia article EC 4.3. ...
Karelsulcia muelleri
... the phenylalanine-tRNA ligase beta-subunit, VARS, elongation factor Tu, the RNA polymerase beta-subunit, and the ribosomal ... and tryptophan. Some strains of "Ca. K. muelleri" are incapable of making the amino acid, tryptophan. It receives its other two ... K. muelleri" lacks a full set of Aminoacyl tRNA synthetases; surprisingly, however, it possesses all of the genes necessary to ... The proteins used were the DNA polymerase III beta-subunit, initiation factor IF-2, leucyl-tRNA synthetase, ...
Aminoacyl tRNA synthetase
An aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase, is an enzyme that attaches the appropriate amino acid onto ... In particular, tryptophanyl-tRNA synthetase (WARS1) will incorporate phenylalanine during tryptophan depletion, essentially ... If the incorrect tRNA is added (aka. the tRNA is found to be improperly charged), the aminoacyl-tRNA bond is hydrolyzed. This ... tRNA + ATP → Aminoacyl-tRNA + AMP + PPi Some synthetases also mediate an editing reaction to ensure high fidelity of tRNA ...
List of enzymes
Glutarate-CoA ligase EC 6.2.1.7: Cholate-CoA ligase EC 6.2.1.8: Oxalate-CoA ligase EC 6.2.1.9: Malate-CoA ligase EC 6.2.1.10: ... L-seryl-tRNA(Sec) selenium transferase EC 2.9.1.2: O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase Hydrolytic ... Tryptophan synthase (EC 4.2.1.20) Category:EC 4.3.1 Phenylalanine ammonia-lyase (EC 4.3.1.24) Category:EC 4.4.1 Cystathionine ... ligase EC 6.2.1.23: Dicarboxylate-CoA ligase EC 6.2.1.24: Phytanate-CoA ligase EC 6.2.1.25: Benzoate-CoA ligase EC 6.2.1.26: o- ...
Biosynthesis
... tRNA ↽ − − ⇀ aminoacyl − tRNA + AMP {\displaystyle {\ce {{Aminoacyl-AMP}+ tRNA <=> {aminoacyl-tRNA}+ AMP}}} The combination of ... Okazaki fragments are covalently joined by DNA ligase to form a continuous strand. Then, to complete DNA replication, RNA ... The other amino acids, valine, methionine, leucine, isoleucine, phenylalanine, lysine, threonine and tryptophan for adults and ... This reaction, called tRNA charging, is catalyzed by aminoacyl tRNA synthetase. A specific tRNA synthetase is responsible for ...
Housekeeping gene
002884 arginyl-tRNA synthetase RARS2 NM_020320 arginyl-tRNA synthetase 2, mitochondrial SARS NM_006513 Homo sapiens seryl-tRNA ... 021178 E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression ... beta polypeptide YWHAH Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, h polypeptide YWHAQ Tyrosine 3- ... 001261434 alanyl-tRNA synthetase domain containing 1 CARS NM_001751 cysteinyl-tRNA synthetase CARS2 NM_024537 cysteinyl-tRNA ...
List of EC numbers (EC 2)
... glutamate-tRNA ligase, EC 1.2.1.70, glutamyl-tRNA reductase and EC 5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase EC 2.7.2.14 ... tryptophan transaminase EC 2.6.1.28: tryptophan-phenylpyruvate transaminase EC 2.6.1.29: diamine transaminase EC 2.6.1.30: ... tRNA (guanine46-N7)-methyltransferase EC 2.1.1.34: tRNA (guanosine18-2′-O)-methyltransferase EC 2.1.1.35: tRNA (uracil54-C5)- ... tRNA (guanine110-N2)-dimethyltransferase EC 2.1.1.214: tRNA (guanine10-N2)-methyltransferase EC 2.1.1.215: tRNA (guanine26-N2/ ...
Ribosomal RNA
... site contains an aminoacyl-tRNA (a tRNA esterified to an amino acid on the 3' end). The P (peptidyl) site contains a tRNA ... Mms1p and Rtt101p are found to bind together and Rtt101p is believed to recruit a ubiquitin E3 ligase complex, allowing for the ... tyrosine and tryptophan) allowing them to form chemical interactions with their associated RNA regions, such as stacking ... In the SSU, the mRNA interacts with the anticodons of the tRNA. In the LSU, the amino acid acceptor stem of the tRNA interacts ...
Glossary of genetics (0-L)
charged tRNA A transfer RNA to which an amino acid has been attached; i.e. an aminoacylated tRNA. Uncharged tRNAs lack amino ... leucine zipper ligase A class of enzymes which catalyze the joining of large molecules such as nucleic acids by forming one or ... Five amino acids (phenylalanine, isoleucine, threonine, tryptophan, and tyrosine) are both glucogenic and ketogenic. ... and most synthetases are cognate to several different tRNAs according to their specific anticodons. aminoacyl-tRNA (aa-tRNA) A ...