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*  Tryptophan hydroxylase
The activity of tryptophan hydroxylase (i.e. the rate at which it converts L-tryptophan into the serotonin precursor L-5- ... Tryptophan Hydroxylase at the US National Library of Medicine Medical Subject Headings (MeSH) See also tryptophan hydroxylase ... The pathway for the synthesis of serotonin from tryptophan Metabolic pathway from tryptophan to serotonin Molecular and ... Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the neurotransmitter serotonin. Tyrosine ...
*  Protein metabolism
Glycine Proline Hydrophobic side chains Alanine Valine Isoleucine Leucine Methionine Phenylalanine Tyrosine Tryptophan Mehta, S ...
*  Fenclonine
Tryptophan hydroxylase activity can be detected neither in cell bodies or nerve terminals. After one week 10% of control values ... Fenclonine, also known as para-chlorophenylalanine (PCPA), acts as a selective and irreversible inhibitor of tryptophan ... PMID 2432781 Early induction of rat brain tryptophan hydroxylase (TPH) mRNA following parachlorophenylalanine (PCPA) treatment ...
*  Tryptophan synthase
... or tryptophan synthetase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan ... Tryptophan is one of the twenty standard amino acids and one of nine essential amino acids for humans. As such, tryptophan is a ... The active sites of tryptophan synthase are allosterically coupled. Subunits: Tryptophan synthase typically exists as an α-ββ-α ... generating the corresponding tryptophan analogues. As humans do not have tryptophan synthase, this enzyme has been explored as ...
*  TPH1
Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. TPH1 was ... Tryptophan hydroxylases catalyze the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5-HTP), which is ... TPH1 tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)". Finocchiaro LM, Arzt ES, Fernández-Castelo S, Criscuolo M, ... 2002). "Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's ...
*  Tryptophan
So high levels of tryptophan prevent tryptophan synthesis through a negative feedback loop, and when the cell's tryptophan ... Hopkins recovered tryptophan from hydrolysed casein, recovering 4-8 g of tryptophan from 600 g of crude casein. As an essential ... Tryptophan is also a precursor to the neurotransmitter serotonin and the hormone melatonin. Like other amino acids, tryptophan ... By this reaction, tryptophan gives rise to tryptophol. Tryptophan affects brain serotonin synthesis when given orally in a ...
*  Tryptophan transaminase
L-tryptophan aminotransferase, and L-tryptophan transaminase. This enzyme participates in tryptophan metabolism. It employs one ... In enzymology, a tryptophan transaminase (EC 2.6.1.27) is an enzyme that catalyzes the chemical reaction L-tryptophan + 2- ... The systematic name of this enzyme class is L-tryptophan:2-oxoglutarate aminotransferase. Other names in common use include L- ... O'Neil SR, DeMoss RD (1968). "Tryptophan transaminase from Clostridium sporogenes". Arch. Biochem. Biophys. 127 (1): 361-9. doi ...
*  Tryptophan repressor
... proteins which make more tryptophan. When the cellular levels of tryptophan decline, the tryptophan molecules on the repressor ... The (tryptophan) repressor is a 25 kD protein homodimer which regulates transcription of the tryptophan biosynthetic pathway in ... When the amino acid tryptophan is in plentiful supply in the cell, trpR binds 2 molecules of tryptophan, which alters its ... The trp operon is active only when cellular tryptophan is scarce. If there isn't enough tryptophan, the repressor protein ...
*  Tryptophan dehydrogenase
In enzymology, a tryptophan dehydrogenase (EC 1.4.1.19) is an enzyme that catalyzes the chemical reaction L-tryptophan + NAD(P ... Vackova K, Mehta A, Kutacek M (1985). "Tryptophan aminotransferase and tryptophan dehydrogenase - activities in some cell ... L-tryptophan dehydrogenase, L-tryptophan dehydrogenase, L-Trp-dehydrogenase, and TDH. This enzyme has at least one effector, ... The systematic name of this enzyme class is L-tryptophan:NAD(P)+ oxidoreductase (deaminating). Other names in common use ...
*  Tryptophan tryptophylquinone
... (TTQ) is an enzyme cofactor, generated by posttranslational modification of amino acids within the ... Amicyanin Davidson VL, Liu A: Uncovering novel biochemistry in the mechanism of tryptophan tryptophylquinone cofactor ...
*  Tryptophan dimethylallyltransferase
L-tryptophan Thus, the two substrates of this enzyme are dimethylallyl diphosphate and L-tryptophan, whereas its two products ... tryptophan dimethylallyl transferase, DMAT synthetase, and 4-(gamma,gamma-dimethylallyl)tryptophan synthase. Lee SL, Floss HG, ... In enzymology, a tryptophan dimethylallyltransferase (EC 2.5.1.34) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase. Other names in ...
*  Tryptophan 2-monooxygenase
In enzymology, a tryptophan 2-monooxygenase (EC 1.13.12.3) is an enzyme that catalyzes the chemical reaction L-tryptophan + O2 ... I. The conversion of L-tryptophan to indole-3-acetamide by an enzyme system from Pseudomonas savastanoi". J. Biol. Chem. 241 ( ... the two substrates of this enzyme are L-tryptophan and O2, and its 3 products are (indol-3-yl)acetamide, CO2, and H2O. This ... The systematic name of this enzyme class is L-tryptophan:oxygen 2-oxidoreductase (decarboxylating). This enzyme participates in ...
*  Tryptophan operon leader
The Tryptophan operon leader is an RNA element found at the 5' of some bacterial tryptophan operons. The leader sequence can ... Tryptophan RNA-binding attenuator protein inhibitory protein (Anti-TRAP protein or AT) is a short protein encoded by the rtpA ... TRAP protein forms an oligomer of 11 subunits, in the presence of tryptophan this binds to section of RNA containing 11 (G/U)AG ... The leader also codes for very short peptide sequence that is rich in tryptophan. The terminator structure is recognised as a ...
*  Tryptophan-phenylpyruvate transaminase
In enzymology, a tryptophan-phenylpyruvate transaminase (EC 2.6.1.28) is an enzyme that catalyzes the chemical reaction L- ... Transamination between tryptophan and phenylpyruvate". Biochem. J. 92 (3): 594-8. PMC 1206107 . PMID 5837443. Molecular and ... The systematic name of this enzyme class is L-tryptophan:phenylpyruvate aminotransferase. This enzyme is also called L- ... tryptophan-alpha-ketoisocaproate aminotransferase. Koide Y, Honma M, Shimomura T (1980). "L-Tryptophan-alpha-ketoisocaproate ...
*  Tryptophan-tRNA ligase
In enzymology, a tryptophan-tRNA ligase (EC 6.1.1.2) is an enzyme that catalyzes the chemical reaction ATP + L-tryptophan + ... tryptophan translase, and TrpRS. This enzyme participates in tryptophan metabolism and aminoacyl-trna biosynthesis. As of late ... The systematic name of this enzyme class is L-tryptophan:tRNATrp ligase (AMP-forming). Other names in common use include ... DAVIE EW, KONINGSBERGER VV, LIPMANN F (1956). "The isolation of a tryptophan-activating enzyme from pancreas". Arch. Biochem. ...
*  Tryptophan 2'-dioxygenase
... tryptophan side chain oxidase type I, TSO I, TSO II, and tryptophan side chain oxidase. This enzyme participates in tryptophan ... tryptophan side-chain alpha,beta-oxidase, tryptophan side chain oxidase II, tryptophan side-chain oxidase, TSO, indolyl-3-alkan ... In enzymology, a tryptophan 2'-dioxygenase (EC 1.13.99.3) is an enzyme that catalyzes the chemical reaction L-tryptophan + O 2 ... A novel tryptophan-metabolizing enzyme". J. Biol. Chem. 252 (8): 2640-7. PMID 15994. Takai K, Ushiro H, Noda Y, Narumiya S, ...
*  Histidine-tryptophan-ketoglutarate
... , or Servator HTK solution is a high-flow, low-potassium preservation solution used for organ ... 4. Pokorny H., et al.: Histidine-tryptophan-ketoglutarate solution for organ preservation in human liver transplantation - a ... 7. Hatano E., et al.: Hepatic preservation with histidine-tryptophan-ketoglutarate solution in living related and cadaveric ... Follow-up experience using histidine-tryptophan-ketoglutarate solution in clinical pancreas transplantation Transplant Proc. ...
*  Tryptophan 7-halogenase
Other flavin-dependent tryptophan halogenases include tryptophan 5-halogenase and tryptophan 6-halogenase. Tryptophan 7- ... Tryptophan 7-halogenase (EC 1.14.19.9, PrnA, RebH) is an enzyme with systematic name L-tryptophan:FADH2 oxidoreductase (7- ... Tryptophan is bound by a number of interactions: other aromatic amino acid residues such as tryptophan, phenylalanine, and ... 7-chloro-L-tryptophan + FAD + 2 H2O The enzyme can use bromide ions (Br−) in place of chloride (Cl−). Tryptophan 7-halogenase ...
*  Tryptophan N-monooxygenase
... (EC 1.14.13.125, tryptophan N-hydroxylase, CYP79B1, CYP79B2, CYP79B3) is an enzyme with systematic ... N-hydroxy-L-tryptophan + NADP+ + H2O (1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ ⇌ {\displaystyle \rightleftharpoons } N,N- ... dihydroxy-L-tryptophan + NADP+ + H2O (1c) N,N-dihydroxy-L-tryptophan ⇌ {\displaystyle \rightleftharpoons } (E)-indol-3- ... Tryptophan N-monooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ...
*  C-glycosyl tryptophan
C-glycosyltryptophan is a sugar-loaded amino acid that strongly correlates with age. "Blood test to estimate your age and predict health". Https:. Retrieved September 9, 2015 ...
*  Tryptophan alpha,beta-oxidase
In enzymology, a tryptophan alpha,beta-oxidase (EC 1.3.3.10) is an enzyme that catalyzes the chemical reaction L-tryptophan + ... Other names in common use include L-tryptophan 2',3'-oxidase, and L-tryptophan alpha,beta-dehydrogenase. It employs one ... Genet R, Benetti PH, Hammadi A, Menez A (1995). "L-tryptophan 2',3'-oxidase from Chromobacterium violaceum. Substrate ... The systematic name of this enzyme class is L-tryptophan:oxygen alpha,beta-oxidoreductase. ...
*  D-tryptophan N-malonyltransferase
N2-malonyl-D-tryptophan Thus, the two substrates of this enzyme are malonyl-CoA and D-tryptophan, whereas its two products are ... The systematic name of this enzyme class is malonyl-CoA:D-tryptophan N-malonyltransferase. Matern U, Feser C, Heller W (1984 ... In enzymology, a D-tryptophan N-malonyltransferase (EC 2.3.1.112) is an enzyme that catalyzes the chemical reaction malonyl-CoA ... CoA and N2-malonyl-D-tryptophan. This enzyme belongs to the family of transferases, specifically those acyltransferases ...
*  Tryptophan 2-C-methyltransferase
Other names in common use include tryptophan 2-methyltransferase, and S-adenosylmethionine:tryptophan 2-methyltransferase. ... In enzymology, a tryptophan 2-C-methyltransferase (EC 2.1.1.106) is an enzyme that catalyzes the chemical reaction S-adenosyl-L ... The systematic name of this enzyme class is S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase. ... L-tryptophan ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + L-2-methyltryptophan Thus, the two substrates of ...
*  Tryptophan-rich sensory protein
... s (TspO) are a family of proteins that are involved in transmembrane signalling. In either ... Davey ME, de Bruijn FJ (December 2000). "A homologue of the tryptophan-rich sensory protein TspO and FixL regulate a novel ...
*  D-tryptophan N-acetyltransferase
Other names in common use include D-tryptophan acetyltransferase, and acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase. Zenk ... N-acetyl-D-tryptophan Thus, the two substrates of this enzyme are acetyl-CoA and D-tryptophan, whereas its two products are CoA ... In enzymology, a D-tryptophan N-acetyltransferase (EC 2.3.1.34) is an enzyme that catalyzes the chemical reaction acetyl-CoA + ... The systematic name of this enzyme class is acetyl-CoA:D-tryptophan N-acetyltransferase. ...