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*  ACTC1
... troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human ...
*  Troponin C type 1
Chemical compounds can bind to troponin C to act as troponin activators (calcium sensitizers) or troponin inhibitors (calcium ... and cardiac troponin T (cTnT), whereas cTnC binds to slow skeletal troponin I (ssTnI) and troponin T (ssTnT) in slow-twitch ... Troponin C, also known as TN-C or TnC, is a protein that resides in the troponin complex on actin thin filaments of striated ... Troponin C is encoded by the TNNC1 gene in humans for both cardiac and slow skeletal muscle. Cardiac troponin C (cTnC) is a 161 ...
*  TNNI3
It is a tissue-specific subtype of troponin I, which in turn is a part of the troponin complex. The TNNI3 gene encoding cardiac ... Vassylyev DG, Takeda S, Wakatsuki S, Maeda K, Maéda Y (Apr 1998). "Crystal structure of troponin C in complex with troponin I ... Noland TA, Raynor RL, Kuo JF (Dec 1989). "Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by ... Martin AF (Jan 1981). "Turnover of cardiac troponin subunits. Kinetic evidence for a precursor pool of troponin-I". The Journal ...
*  Tropomyosin
Calcium ions then bind to troponin, which is associated with tropomyosin. Binding causes changes in the shape of troponin and ... The thin filament is made of actin, tropomyosin, and troponin. The contraction of skeletal muscle is triggered by nerve ... Structural and biochemical studies suggest that the position of tropomyosin and troponin on the thin filament regulates the ... Causative mutations have been detected in skeletal α-actinin, tropomyosin, nebulin, and troponin. Within humans, mutations in ...
*  Troponin I
Troponin Troponin T Troponin C Troponin I at the US National Library of Medicine Medical Subject Headings (MeSH) https:// ... Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin- ... Troponin I is not entirely specific for myocardial damage secondary to infarction. Other causes of raised Troponin I include ... When calcium binds to the troponin C it causes conformational changes which lead to dislocation of troponin I and finally ...
*  Cardiac marker
For example, in formal usage, troponin would not be listed as a cardiac enzyme. Measuring cardiac biomarkers can be a step ... "Cardiac troponin I and cardiac enzymes after electrophysiologic studies, ablations, and defibrillator implantations". Am. J. ...
*  TNNI1
It is a tissue-specific subtype of troponin I, which in turn is a part of the troponin complex. Gene TNNI1, troponin I type 1 ( ... troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast". Biochemical and Biophysical Research Communications. 230 ... "Entrez Gene: TNNI1 troponin I type 1 (skeletal, slow)". Perry SV (Jan 1999). "Troponin I: inhibitor or facilitator". Molecular ... results in binding to the N-terminal domain of troponin C and induces conformational changes in troponin C and the troponin ...
*  Actin, alpha 1
A novel troponin T-like protein". Hypertension. 11 (6 Pt 2): 620-6. doi:10.1161/01.hyp.11.6.620. PMID 2455687. Taylor A, Erba ... 1991). "Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from ...
*  Troponin
... , or the troponin complex, is a complex of three regulatory proteins (troponin C, troponin I, and troponin T) that is ... Troponin T Troponin I Troponin C Calcium-binding protein PDB: 1J1E​; Takeda S, Yamashita A, Maeda K, Maeda Y (2003). "Structure ... interlocking them to form a troponin-tropomyosin complex Troponin I binds to actin in thin myofilaments to hold the troponin- ... Troponin is found in both skeletal muscle and cardiac muscle, but the specific versions of troponin differ between types of ...
*  Troponin T
Troponin Troponin C Troponin I Calcium-binding protein Troponin T at the US National Library of Medicine Medical Subject ... Troponin T is a part of troponin complex expressed in skeletal and cardiac myocytes. Troponin complex is responsible for ... Cardiac troponin T2, TNNT2 (1q32, 191045) Fast skeletal troponin T3, TNNT3 (11p15.5, 600692) Increased troponin T levels after ... Troponin T is a part of the troponin complex, where it binds to tropomyosin and helps position it on actin, and together with ...
*  Troponin C
Troponin Troponin T Troponin I Calcium-binding protein Troponin C at the US National Library of Medicine Medical Subject ... Troponin C is a part of the troponin complex. It contains four calcium-binding EF hands, although different isoforms may have ... The C lobe serves a structural purpose and binds to the N domain of troponin I (TnI). The C lobe can bind either Ca2+ or Mg2+. ... The N lobe, which binds only Ca2+, is the regulatory lobe and binds to the C domain of troponin I after calcium binding. The ...
*  TNNT2
Cardiac TnT is the largest of the three troponin subunits (cTnT, troponin I (TnI), troponin C (TnC)) on the actin thin filament ... "Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T". ... He X, Liu Y, Sharma V, Dirksen RT, Waugh R, Sheu SS, Min W (Jul 2003). "ASK1 associates with troponin T and induces troponin T ... Noland TA, Raynor RL, Kuo JF (Dec 1989). "Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by ...
*  Reference ranges for blood tests
"Troponins". medscape. Retrieved 2017-07-24. Updated: Jan 14, 2015 Brenden CK, Hollander JE, Guss D, et al. (May 2006). "Gray ... In addition, some values, including troponin I and brain natriuretic peptide, are given as the estimated appropriate cutoffs to ...
*  Tropomyosin 3
A novel troponin T-like protein". Hypertension. 11 (6 Pt 2): 620-6. doi:10.1161/01.hyp.11.6.620. PMID 2455687. Coulier F, ...
*  Fetal protein
Fetal Troponin T and Troponin I isoforms.. ...
*  C-Raf
Pfleiderer P, Sumandea MP, Rybin VO, Wang C, Steinberg SF (2009). "Raf-1: a novel cardiac troponin T kinase". J. Muscle Res. ... cardiac muscle troponin T (TnTc), etc. The retinoblastoma protein (pRb) and Cdc25 phosphatase were also suggested as possible ...
*  Smooth muscle tissue
Smooth muscle does not contain the protein troponin; instead calmodulin (which takes on the regulatory role in smooth muscle), ... Contraction is initiated by a calcium-regulated phosphorylation of myosin, rather than a calcium-activated troponin system. ... smooth muscle does not contain the calcium-binding protein troponin. ...
*  Polycystin 2
Li, Qiang; Shen Patrick Y; Wu Guanqing; Chen Xing-Zhen (Jan 2003). "Polycystin-2 interacts with troponin I, an angiogenesis ...
*  Myocardial contractility
3. Sensitizing troponin-C to the effects of calcium. 4. Phosphorylating L-type calcium channels. This will increase their ... More calcium available for Troponin to use will increase the force developed. Decreasing contractility is done primarily ...
*  Heart
Calcium ions also combine with the regulatory protein troponin C in the troponin complex to enable contraction of the cardiac ... Two tests of troponin are often taken - one at the time of initial presentation, and another within 3-6 hours, with either a ... Troponin is a sensitive biomarker for a heart with insufficient blood supply. It is released 4-6 hours after injury, and ... These are mostly associated with muscle contraction, and bind with actin, myosin, tropomyosin, and troponin. They include MYH6 ...
*  TPM1
Tanokura M, Ohtsuki I (1984). "Interactions among chymotryptic troponin T subfragments, tropomyosin, troponin I and troponin C ... Pearlstone JR, Smillie LB (1983). "Effects of troponin-I plus-C on the binding of troponin-T and its fragments to alpha- ... In human cardiac muscle the ratio of α-Tm to β-Tm is roughly 5:1. Tm functions in association with the troponin complex to ... In addition to actin, Tm binds troponin T (TnT). TnT tethers the region of head-to-tail overlap of subsequent Tm molecules to ...
*  Heart-type fatty acid binding protein
H-FABP measured with troponin shows increased sensitivity of 20.6% over troponin at 3-6 hours following chest pain onset. This ... The effectiveness of using the combination of H-FABP with troponin to diagnose MI within 6 hours is well reported. In addition ... FABP3 is known to interact with TNNI3K in the context of interacting with cardiac troponin I. The protein also interacts with, ... Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically ...
*  Acute pericarditis
Troponin levels increase in 35-50% of people with pericarditis. Electrocardiogram (ECG) changes in acute pericarditis mainly ... Acute pericarditis is associated with a modest increase in serum creatine kinase MB (CK-MB). and cardiac troponin I (cTnI), ...
*  Calcium-binding protein 1
Tsalkova TN, Privalov PL (1985). "Thermodynamic study of domain organization in troponin C and calmodulin". Journal of ...
*  Calponin 1
"Isoform diversity, regulation, and functional adaptation of troponin and calponin". Critical Reviews in Eukaryotic Gene ... "A novel troponin T-like protein (calponin) in vascular smooth muscle: interaction with tropomyosin paracrystals". Journal of ...