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*  Tricarboxylic acid
Citric acid, a type of tricarboxylic acid, is used in the citric acid cycle - also known as tricarboxylic acid (TCA) cycle or ... Citric acid cycle (tricarboxylic acid cycle) Dicarboxylic acid Mellitic acid Ryan J. Mailloux, Robin Bériault, Joseph Lemire, ... A tricarboxylic acid is an organic carboxylic acid whose chemical structure contains three carboxyl functional groups (-COOH). ... The best-known example of a tricarboxylic acid is citric acid. ... "The Tricarboxylic Acid Cycle, an Ancient Metabolic Network with ...
*  Propane-1,2,3-tricarboxylic acid
3-tricarboxylic acid, also known as tricarballylic acid, carballylic acid, and β-carboxyglutaric acid, is a tricarboxylic acid ... Propane-1,2,3-tricarboxylic acid can be synthesized in two steps from fumaric acid. Citric acid Aconitic acid Isocitric acid ... the interconversion of citric acid into isocitric acid (see figure above). Propane-1,2,3-tricarboxylic acid is well suited to ... 3-tricarboxylic acid. Russell, James B.; Forsberg, Neil (2007). "Production of tricarballylic acid by rumen microorganisms and ...
*  Metabolon
doi:10.1016/0303-2647(89)90038-5. Lyubarev A. E., Kurganov B. I. Supramolecular organisation of Tricarboxylic Acids Cycle's ... Lyubarev, A. E.; Kurganov, B. I. (1989). "Supramolecular organization of tricarboxylic acid cycle enzymes". Biosystems. 22 (2 ... "Protein-protein interactions and metabolite channelling in the plant tricarboxylic acid cycle". Nature Communications. 8: 15212 ... The citric acid cycle is an example of a metabolon that facilitates substrate channeling. Another example is the dhurrin ...
*  Defense in insects
Hence, 3-NPA inhibits the tricarboxylic acid cycle. This inhibition leads to neurodegeneration with symptoms similar to those ... The degradation of such essential amino acids provides propanoyl-CoA. This compound is further transformed into propanoic acid ... Essential amino acids as valine serve as precursors for the production of the hemolymph toxins of Chrysomelina leaf beetles. ... The amino group in β-alanine is then oxidized to yield either an oxime or the nitro-toxin 3-nitropropanoic acid (3-NPA). The ...
*  Metal-organic framework
BDC or teraphthalic acid, biphenyl-4,4'-dicarboxylic acid (BPDC), and the tricarboxylic acid trimesic acid. The study of MOFs ... and tricarboxylic acids. These ligands typically have rigid backbones. Examples are benzene-1,4-dicarboxylic acid ( ... Thus, the framework-incorporated amino acid can exist in a form that is not accessible for the free amino acid. While the ... The anhydrous version of HKUST-1 is an acid catalyst. Compared to Brønsted vs. Lewis acid-catalyzed pathways, the product ...
*  Timeline of biology and organic chemistry
1937 - Hans Adolf Krebs discovered the tricarboxylic acid cycle. 1937 - In Genetics and the Origin of Species, Theodosius ... 1907 - Hermann Emil Fischer artificially synthesized peptide amino acid chains and thereby shows that amino acids in proteins ... 1869 - Friedrich Miescher discovered nucleic acids in the nuclei of cells. 1874 - Jacobus van 't Hoff and Joseph-Achille Le Bel ... 1961 - J. Heinrich Matthaei cracked the first codon of the genetic code (the codon for the amino acid phenylalanine) using ...
*  Oxalomalate lyase
"Glutamate biosynthesis in an organism lacking a Krebs tricarboxylic acid cycle. V. Isolation of alpha-hydroxy-gamma- ... This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic ...
*  CALS Table Model
N-(2-hydroxyethyl)iminodiacetic acid. Carboxyglutamate 3-Aminopropane-1,1,3-tricarboxylic acid. OASIS is the Organization for ... 2-carboxymethoxy-aniline-N,N-diacetic acid. BAPTA 1,2-bis(-2-aminophenoxy)ethane- N,N,N',N'-tetraacetic acid. HIDA ... 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid (ethylenediamine tetraacetic acid). AATA 2,2'-(2-(2-(2-(bis( ... 2,2',2'',2'''-(2,2'-(1,2-phenylene bis(oxy))bis(ethane-2,1-diyl)) bis(azanetriyl)tetraacetic acid. EGTA ethylene glycol-bis(2- ...
*  Pyruvate cycling
November 2004). "Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase ... and hepatic tricarboxylic acid cycle fluxes measured by nuclear magnetic resonance analysis of a single glucose derivative". ... and Pyruvate Cycling but a Decreased γ-Aminobutyric Acid Shunt". The Journal of Biological Chemistry. 283 (25): 17238-49. doi: ...
*  Green sulfur bacteria
They are autotrophs that utilize the reverse tricarboxylic acid cycle to fix carbon dioxide. Green sulfur bacteria are often ... The reactions of reversal of the osixative tricarboxylic acid cycle are catalyzed by four enzymes: pyruvate:ferredoxin (Fd) ... These autotrophs fix carbon dioxide using the reverse tricarboxylic acid (RTCA) cycle. Energy is consumed to incorporate carbon ...
*  Acetyl-CoA carboxylase
Martin DB, Vagelos PR (June 1962). "The Mechanism of Tricarboxylic Acid Cycle Regulation of Fatty Acid Synthesis". J Biol Chem ... When the enzyme is active, the product, malonyl-CoA, is produced which is a building block for new fatty acids and can inhibit ... L Abu-Elheiga; M M Matzuk; K A Abo-Hashema; S J Wakil (March 2001). "Continuous Fatty Acid Oxidation and Reduced Fat Storage in ... The most important function of ACC is to provide the malonyl-CoA substrate for the biosynthesis of fatty acids. The activity of ...
*  Hans Kornberg
Kornberg, H. L.; Krebs, H. A. (1957). "Synthesis of cell constituents from C2-units by a modified tricarboxylic acid cycle". ...
*  3-Carboxy-cis,cis-muconic acid
1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylic acid - Compound Summary". PubChem Compound. USA: National Center for Biotechnology ... 3-Carboxy-cis,cis-muconic acid is a metabolite of the catechin degradation by Bradyrhizobium japonicum. The enzyme 3-carboxy- ...
*  Aldol condensation
4-tricarboxylic Acid, "Isoprenetricarboxylic Acid"". Journal of Organic Chemistry. 70 (18): 7429-7431. doi:10.1021/jo0507892. ... Then campholenic aldehyde (1) is added and the mixture refluxed for 15 h. Then 2N hydrochloric acid is added and the mixture ... The first step is formation of the Transition metal carbene complex 2. Acetic acid adds to this intermediate in a nucleophilic ... The combined organic layers are washed with 2N hydrochloric acid, saturated sodium bicarbonate and brine. The organic phase is ...
*  Anabaena variabilis
Pearce, J.; Leach, C. K.; Carr, N. G. (1969). "The Incomplete Tricarboxylic Acid Cycle in the Blue-green Alga Anabaena ...
*  Oxalosuccinic acid
... /oxalosuccinate is an unstable 6-carbon intermediate in the tricarboxylic acid cycle. It's an alpha-keto ... Oxalosuccinic acid is a substrate of the citric acid cycle. It is acted upon by isocitrate dehydrogenase. Salts and esters of ...
*  Metabolism
Kornberg H, Krebs H (1957). "Synthesis of cell constituents from C2-units by a modified tricarboxylic acid cycle". Nature. 179 ... lack all amino acid synthesis and take their amino acids directly from their hosts. All amino acids are synthesized from ... Fatty acids are made by fatty acid synthases that polymerize and then reduce acetyl-CoA units. The acyl chains in the fatty ... Amino acid synthesis depends on the formation of the appropriate alpha-keto acid, which is then transaminated to form an amino ...
*  Hans Adolf Krebs
Kornberg, HL; Krebs, HA (1957). "Synthesis of cell constituents from C2-units by a modified tricarboxylic acid cycle.\". Nature ... Krebs, HA; Johnson, WA (1937). "Acetopyruvic acid (alphagamma-diketovaleric acid) as an intermediate metabolite in animal ... Krebs continued to add more details to his citric acid cycle. The discovery of acetyl-CoA in 1947 by Fritz Albert Lipmann was ... These two reactions did not follow the normal citric acid cycle, and hence the pathway was named the glyoxylate bypass of the ...
*  Isocitrate lyase
Together with malate synthase, it bypasses the two decarboxylation steps of the tricarboxylic acid cycle (TCA cycle) and is ... Kornberg, HL; Krebs HA (18 May 1957). "Synthesis of cell constituents from C2-units by a modified tricarboxylic acid cycle". ... These additional amino acids account for the difference in molecular mass: the prokaryotic ICL is 48kDa, while the eukaryotic ... I. Preparation, amino acid composition and molecular weight". Biochim. Biophys. Acta. 96: 114-22. doi:10.1016/0005-2787(65) ...
*  Malate oxidase
Hebeler, B. H.; Morse, S. A. (1976-10-01). "Physiology and metabolism of pathogenic neisseria: tricarboxylic acid cycle ... Cohn, D. V. (1958-08-01). "The enzymatic formation of oxalacetic acid by nonpyridine nucleotide malic dehydrogenase of ... "The enzymatic formation of oxalacetic acid by nonpyridine nucleotide malic dehydrogenase of Micrococcus lysodeikticus". J. Biol ...
*  Citric acid
... aconitic acid, and propane-1,2,3-tricarboxylic acid (tricarballylic acid, carballylic acid) Acids in wine "citric acid". ... Citric acid is a weak organic tricarboxylic acid having the chemical formula C6H8O7. It occurs naturally in citrus fruits. In ... Citric acid can be used as an alternative to nitric acid in passivation of stainless steel. Citric acid can be used as a lower- ... Citric acid is an alpha hydroxy acid and used as an active ingredient in chemical peels. Citric acid is commonly used as a ...
*  GOT2
GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. Also, GOT2 is a major participant in the ... Zhou SL, Gordon RE, Bradbury M, Stump D, Kiang CL, Berk PD (Apr 1998). "Ethanol up-regulates fatty acid uptake and plasma ... Another function of GOT2 is that it is believed to transaminate kynurenine into kynurenic acid (KYNA) in the brain. The KYNA ... Virtually ubiquitous in eukaryotic cells, GOT2 nucleic acid and protein sequences are highly conserved, and its 5'regulatory ...
*  Desulfobacter hydrogenophilus
A modified tricarboxylic acid (TCA) cycle is employed for acetate metabolism and autotrophic growth. When D. hydrogenophilus is ... Cis-9,10-methylenehexadecanoic acid and 10-methylhexadecanoic acid have been considered biomarkers for D. hydrogenophilus. ... The fatty acid methyl esters (FAME) detected in D. hydrogenophilus consist of a wide variety of structures, including normal, ... Fatty acid δ13C values were more depleted relative to biomass under heterotrophic (−13.3‰) than under autotrophic (−11.8‰) ...
*  IDH3A
NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid ... Alignment of their amino acid sequences reveals ~40% identity between IDH3α and IDH3β, ~42% identity between IDH3α and IDH3γ, ...
*  GOT1
GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show ... Doyle JM, Schininà ME, Bossa F, Doonan S (1990). "The amino acid sequence of cytosolic aspartate aminotransferase from human ...
*  Sulfolobus
... tricarboxylic/Krebs/citric acid) cycle. This indicates that Sulfolobus has a TCA cycle system similar to that found in ... The tetraethers help Sulfolobus species survive extreme acid as well as high temperature. S. solfataricus has been found in ...