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*  Iron overload
Lu JP, Hayashi K. Transferrin receptor distribution and iron deposition in the hepatic lobule of iron-overloaded rats. Pathol ... ISBN 0-07-470436-2. [page needed] Lu JP, Hayashi K. Transferrin receptor distribution and iron deposition in the hepatic lobule ... Transferrin Last reviewed on October 28, 2009. Pietrangelo, Antonello (2010). "Hereditary Hemochromatosis: Pathogenesis, ...
*  Hepcidin
... transferrin receptor 2, bone morphogenic protein 6 (BMP6), matriptase-2, neogenin, BMP receptors, and transferrin. ...
*  Transferrin
... bound to its receptor. Transferrin receptor complex. The liver is the main site of transferrin synthesis but other ... Beta-2 transferrin Transferrin receptor Total iron-binding capacity Transferrin saturation Ferritin GRCh38: Ensembl release 89 ... Each transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+ ). The gene coding for transferrin in ... Transferrin glycoproteins bind iron tightly, but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of ...
*  Transferrin saturation
Of the transferrin that is available to bind iron, this value tells a clinician how much serum iron is bound. For instance, a ... Transferrin saturation, measured as a percentage, is a medical laboratory value. It is the value of serum iron divided by the ... Normal reference ranges are: Serum iron: 60-170 μg/dL (10-30 μmol/L) Total iron-binding capacity: 240-450 μg/dL Transferrin ... value of 15% means that 15% of iron-binding sites of transferrin are being occupied by iron. For an explanation of some ...
*  Conalbumin
Transferrins, are iron binding proteins and acute phase reactants of animal serum. It has a binding log of 15 at a pH of 7 or ... The primary sequence of ovotransferrin is similar to that of many serum transferrins found in other species. Recently, ... As a member of the transferrin and metalloproteinase family, ovotransferrin has been found to produce heat shock proteins. When ... scientists have discovered a blood serum transferrin in humans, that binds iron like Ovotransferrin and which shows 50% ...
*  Transferrin receptor
Earlier two transferrin receptors in humans, transferrin receptor 1 and transferrin receptor 2 had been characterized and until ... "Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary ... Transferrin receptor (TfR) is a carrier protein for transferrin. It is needed for the import of iron into the cell and is ... Transferrin receptor 1 Transferrin receptor 2 GAPDH Qian ZM, Li H, Sun H, Ho K (December 2002). "Targeted drug delivery via the ...
*  Lactoferrin
Exons of the lactoferrin gene in oxen have a similar size to the exons of other genes of the transferrin family, whereas the ... Lactoferrin is one of the transferrin proteins that transfer iron to the cells and control the level of free iron in the blood ... Lactoferrin forms reddish complex with iron; its affinity for iron is 300 times higher than that of transferrin. The affinity ... Xavier PL, Chaudhari K, Verma PK, Pal SK, Pradeep T (2010). "Luminescent quantum clusters of gold in transferrin family protein ...
*  Iron deficiency
Blood plasma as a result carries iron tightly bound to transferrin, which is taken up by cells by endocytosing transferrin, ... In blood plasma, iron is carried tightly bound to the protein transferrin. There are several mechanisms that control human iron ...
*  Total iron-binding capacity
... which indirectly measures transferrin since transferrin is the most dynamic carrier. TIBC is less expensive than a direct ... The percent transferrin saturation (i.e., the result of the formula of serum iron/TIBC x 100) can also be a useful indicator. ... Total iron-binding capacity (TIBC) or sometimes transferrin iron-binding capacity is a medical laboratory test that measures ... Taken together with serum iron and percent transferrin saturation clinicians usually perform this test when they are concerned ...
*  HAMP
... evidence for a regulation in response to the serum transferrin saturation and to non-transferrin-bound iron". Blood. 102 (1): ...
*  Iron response element
In contrast, binding to multiple IREs in the 3' UTR of the transferrin receptor (involved in iron acquisition) leads to ... "A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA". ...
*  Human iron metabolism
... also acts as a transferrin receptor. Transferrin-bound ferric iron is recognized by these transferrin receptors, triggering a ... "Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary ... Most cell types take up iron primarily through receptor-mediated endocytosis via transferrin receptor 1 (TFR1), transferrin ... TFR1 has a 30-fold higher affinity for transferrin-bound iron than TFR2 and thus is the main player in this process. The higher ...
*  Ferritin
Mizuno S, Mihara T, Miyaoka T, Inagaki T, Horiguchi J (March 2005). "CSF iron, ferritin and transferrin levels in restless legs ... Bacterioferritin DNA-binding protein from starved cells Ferritin light chain Transferrin ; Granier T, Langlois d'Estaintot B, ...
*  Endosome
... iron is released from the transferrin, and then the iron-free transferrin (still bound to the transferrin receptor) returns ... 1983). "Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells". Journal of ... 50 nm diameter). Markers include RAB5A and RAB4, Transferrin and its receptor and EEA1. Late endosomes, also known as MVBs, are ... Transferrin also remains associated with its receptor, but, in the acidic endosome, ...
*  Gallium scan
Gallium (III) (Ga3+) binds to transferrin, leukocyte lactoferrin, bacterial siderophores, inflammatory proteins, and cell- ...
*  Iron-responsive element-binding protein
And more transferrin receptors make it easier for the cell to bring in more iron from transferrin-iron complexes circulating ... The transferrin receptor mRNA is rapidly degraded without the IRE-BP attached to it. The cell stops producing transferrin ... Since iron is tightly bound to transferrin, cells throughout the body have receptors for transferrin-iron complexes on their ... On its own, the IRE-BP binds to the IREs of ferritin and transferrin receptor mRNA. But, when iron binds to the IRE-BP, the IRE ...
*  Carbohydrate deficient transferrin
Carbohydrate-deficient transferrin (CDT) is a laboratory test used to help detect heavy ethanol consumption. Transferrin is a ... These are referred to as carbohydrate-deficient transferrins. These carbohydrate-deficient transferrins can be measured in the ... Carbohydrate-deficient transferrin is elevated in the blood of heavy alcoholism but raised levels can also be found in a number ... Various forms of transferrin exist, with differing levels of sialylation. The most common form is tetrasialotransferrin, with ...
*  Haemochromatosis type 3
... is a type of Iron overload disorder associated with deficiencies in transferrin receptor 2. It exhibits ... 2002). "Hemochromatosis due to mutations in transferrin receptor 2". Blood Cells Mol. Dis. 29 (3): 465-70. doi:10.1006/bcmd. ... May 2001). "New mutations inactivating transferrin receptor 2 in hemochromatosis type 3". Blood. 97 (9): 2555-60. doi:10.1182/ ...
*  Transferrin receptor 1
"Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary ... Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is ... Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. TfR1 as ... TfR1 is required for iron import from transferrin into cells by endocytosis. TfR1 is a transmembrane glycoprotein composed of ...
*  Soluble transferrin receptor
... conventionally refers to the cleaved extracellular portion of transferrin receptor 1 that is ... has been reported as a soluble receptor for transferrin. It has been demonstrated to deliver more transferrin as compared to ... Ferritin Transferrin Total iron binding capacity Cook, J. D.; Skikne, B. S.; Baynes, R. D. (1 February 1993). "Serum ... Blood testing of the soluble transferrin receptor (sTfR) is used as a measure of functional iron staus and the investigation of ...
*  Diferric-transferrin reductase
Other names in common use include diferric transferrin reductase, NADH diferric transferrin reductase, and transferrin ... In enzymology, a diferric-transferrin reductase (EC 1.16.1.2) is an enzyme that catalyzes the chemical reaction transferrin[Fe( ... transferrin[Fe(II)]2]], NAD+, and H+, whereas its two products are [[transferrin[Fe(III)]2]] and NADH. This enzyme belongs to ... The systematic name of this enzyme class is transferrin[Fe(II)]2:NAD+ oxidoreductase. ...
*  Beta-2 transferrin
... is a carbohydrate-free (desialated) isoform of transferrin, which is almost exclusively found in the ... Thus, beta-2 transferrin in otorrhea would be suggestive of either a CSF leak or a perilymph leak. Chan D, Poon W, IP C, Chiu P ... Beta-2 transferrin would also be positive in patients with perilymph fluid leaks, as it is also present in inner ear perilymph ... Skedros DG, Cass SP, Hirsch BE, Kelly RH (Oct 1993). "Beta-2 transferrin assay in clinical management of cerebral spinal fluid ...
*  Transferrin receptor 2
2001). "Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary ... Transferrin receptor 1 Transferrin GRCh38: Ensembl release 89: ENSG00000106327 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... 1999). "Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family". J. Biol. Chem. 274 ... 2003). "Heterotypic interactions between transferrin receptor and transferrin receptor 2". Blood. 101 (5): 2008-14. doi:10.1182 ...
*  Composition of the human body
Transferrins can bind aluminium. Periodic table highlighting dietary elements The composition of the human body is expressed in ...
*  Polymorphism (biology)
Genetic polymorphism of serum transferrins in reindeer is used in population and genetic studies. Gene concentrations of ... Brænd, Mikael (December 1964). "Genetic studies on serum transferrins in reindeer". Hereditas. 52 (2): 181-188. doi:10.1111/j. ... 1601-5223.1964.tb01950.x. Zhurkevich, N.M.; Fomicheva, I. I. (1976). "Genetic polymorphism of the serum transferrins of the ...