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*  Histone deacetylase
This decreased binding allows chromatin expansion, permitting genetic transcription to take place. Histone deacetylases remove ... NF-κB is a key transcription factor and effector molecule involved in responses to cell stress, consisting of a p50/p65 ... HDIs have been shown to alter the activity of many transcription factors, including ACTR, cMyb, E2F1, EKLF, FEN 1, GATA, HNF-4 ... It is a mistake to regard HDACs solely in the context of regulating gene transcription by modifying histones and chromatin ...
*  Biochemical cascade
Self-renewal process is highly regulated from cell cycle and genetic transcription control. There are some signaling pathways, ... Given the genetic makeup of an organism, the complete set of possible reactions constitutes its reactome. Reactome, located at ... This response is slower than the first because it involves more steps, like transcription of genes and then the effect of newly ... The WNT pathway allows β-catenin function in gene transcription, once the interaction between WNT ligand and G protein-coupled ...
*  R-loop
"Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability". Mol. Cell. 67 (4): 608-621.e6. doi: ... Drolet, M; Bi, X; Liu, LF (1994). "Hypernegative supercoiling of the DNA template during transcription elongation in vitro". J ... This discovery of endogenous R-loops, in conjunction with rapid advances in genetic sequencing technologies, inspired a ... 2017) speculated that the function of introns in maintaining genetic stability may explain their evolutionary maintenance at ...
*  Intron
"Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability". Mol. Cell. 67 (4): 608-621.e6. doi: ... Lynch M (April 2002). "Intron evolution as a population-genetic process". Proceedings of the National Academy of Sciences. 99 ( ... 2017) speculated that the function of introns in maintaining genetic stability may explain their evolutionary maintenance at ... together with genetic and biochemical analysis of RNA splicing reactions. At least four distinct classes of introns have been ...
*  Primary transcript
"Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability". Mol. Cell. 67 (4): 608-621.e6. doi: ... Transcription factors, proteins that bind to DNA elements to either activate or repress transcription, bind to enhancers and ... Activation of transcription depends on whether or not the transcription elongation complex, itself consisting of a variety of ... Histone modification by transcription factors is another key regulatory factor for transcription by RNA polymerase. In general ...
*  HHV Latency Associated Transcript
The LAT RNA is produced by genetic transcription from a certain region of the viral DNA. LAT regulates the viral genome and ... Genetic studies of the LAT-DNA have identified a portion known as a chromatin insulator which forms a boundary between ... Acetylation of Histone promotes transcription of DNA to RNA, and then to protein products. A March 2006 University of Florida ... CTCF binding to DNA may result in formation of transcription-ready euchromatin through the Histone H3-acetylating activity ...
*  Cycle (gene)
Cycle is primarily known for its role in the genetic transcription-translation feedback loop that generates circadian rhythms ... The cyc gene is located on the left arm of chromosome 3 and codes for a transcription factor containing a basic helix-loop- ... Assaying PER and TIM transcription levels in the cyc mutant showed reduced mRNA levels of both proteins. Cloning of the cyc ... Cyc is involved with the genetic basis of other behaviors that relate to circadian processes, such as sleep, which is important ...
*  Casein kinase 1
CK1ε and CK1δ are essential in the genetic transcription-translation (and post-translation) feedback loops that generate ... CK1ε may also have a role in positive feedback; the transcription factor BMAL1 is a CK1ε substrate in vitro, and increased CK1ε ... Phosphorylation of the PER proteins also leaves them unable to enter the nucleus, where they suppress transcription of clock ... CK1 isoforms are involved in Wnt signaling, circadian rhythms, nucleo-cytoplasmic shuttling of transcription factors, DNA ...
*  Acetyl group
... allowing for genetic transcription to occur. However, removal of the acetyl group by histone deacetylases (HDACs) condenses DNA ... and this is another common way to block DNA acetylation and inhibit gene transcription.[citation needed] Acetylation can be ... structure, thereby preventing transcription. In addition to HDACs, Methyl group additions are able to bind DNA resulting in DNA ...
*  DSCR1
... by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways of genetic transcription, ...
*  Avian sarcoma leukosis virus
... an enzyme that allows for the reversal of genetic transcription. As with all retroviruses, the virus is transcribed from RNA to ...
*  Tetracycline-controlled transcriptional activation
Thus the introduction of doxycycline to the system initiates the transcription of the genetic product. The Tet-On system is ... However, the Tet system, which depends on transcription and subsequent translation of a target gene, is not as fast-acting as ... Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly ...
*  Nanorobotics
They go through a process called reverse transcription to deliver genetic packaging in a vector. Usually, these devices are Pol ...
*  Genesee Scientific
May 2009). "Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication". PLoS Genetics. 5: e1000474. doi: ...
*  Circadian clock
In these cells, there was no transcription or genetic circuits, and therefore no feedback loop. Similar observations were made ... While RORs activate transcription of Bmal1, REV-ERBs repress the same transcription process. Hence, the circadian oscillation ... Evidence for a genetic basis of circadian rhythms in higher eukaryotes began with the discovery of the period (per) locus in ... In flies, CLK-CYC binds to the promoters of circadian-regulated genes only at the time of transcription. A stabilizing loop ...
*  Cell nucleus
The nucleus provides a site for genetic transcription that is segregated from the location of translation in the cytoplasm, ... They are transcription dependent and in the absence of RNA Pol II transcription, the paraspeckle disappears and all of its ... Transcription of the rDNA occurs either in the FC or at the FC-DFC boundary, and, therefore, when rDNA transcription in the ... The transcription, post-transcriptional processing, and assembly of rRNA occurs in the nucleolus, aided by small nucleolar RNA ...
*  NFE2L1
... an NF-E2-related transcription factor, by genetic selection in yeast". Proceedings of the National Academy of Sciences of the ... Zhang Y, Lucocq JM, Hayes JD (Mar 2009). "The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is ... Wang W, Kwok AM, Chan JY (Aug 2007). "The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription". ... Marini MG, Chan K, Casula L, Kan YW, Cao A, Moi P (Jun 1997). "hMAF, a small human transcription factor that heterodimerizes ...
*  Biocomplexity
Classical examples of biocomplexity include the behavior of molecular motors during DNA transcription, genetic and metabolic ...
*  Noise (spectral phenomenon)
... errors in genetic transcription Noise in computer graphics refers to various pseudo-random functions used to create textures, ...
*  Abortive initiation
... , also known as abortive transcription, is an early process of genetic transcription in which RNA polymerase ... Oligonucleotide Eukaryotic transcription Bacterial transcription Revyakin A, Liu C, Ebright RH, Strick TR (2006). "Abortive ... During this early stage of transcription, RNA polymerase enters a phase during which dissociation of the transcription complex ... When RNA polymerase undergoes abortive transcription in the presence of ATP, UTP, and GTP, a complex is formed that has a much ...
*  Initiation (disambiguation)
... an early process of genetic transcription Chain initiation, the beginning of chain-growth polymerization Initiation (neurology ... the process of beginning gene transcription Initiation as beginning of gene translation Initiation factor, proteins that bind ...
*  Human mitochondrial molecular clock
"Ancient mtDNA genetic variants modulate mtDNA transcription and replication", PLoS Genet., 5 (5): e1000474, doi:10.1371/journal ... Random genetic drift may also cause the loss of mutations. For these reasons, the actual mutation rate will not be equivalent ... A major assumption of the molecular clock theory is that mutations within a particular genetic system occur at a statistically ... 2003 suggests that selection, saturation, parallel mutations and genetic drift are responsible for the differences observed ...
*  Mitochondrial Eve
"Ancient mtDNA genetic variants modulate mtDNA transcription and replication", PLoS Genet., 5 (5): e1000474, doi:10.1371/journal ... Without a DNA sample, it is not possible to reconstruct the complete genetic makeup (genome) of any individual who died very ... Better defined is the genetic separation among Neanderthals, Flores hobbit, Java man, and Peking man. In 1999 Krings et al. ... Of all the non-African hominids, European archaics most closely resembled humans, indicating a wider genetic divide with other ...
*  Transcription factor II F
"Genetic characterization of general transcription factors TFIIF and TFIIB of Homo sapiens sapiens". Cytogenet. Cell Genet. 69 ( ... Transcription factor IIF (TFIIF) is one of several general transcription factors that make up the RNA polymerase II ... Transcription factor IIF is encoded by the GTF2F1, GTF2F2, and GTF2F2L genes. TFIIF binds to RNA Pol II when the enzyme is ... Transcription Factor TFIIF at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Heritability of autism
A genetic variant that disrupts MET transcription is associated with autism. Proc Natl Acad Sci USA. 2006;103(45):16834-9. doi: ... The Autism Genome Project database contains genetic linkage and CNV data that connect autism to genetic loci and suggest that ... then the condition is considered to be primarily genetic. Autism has a strong genetic basis, although the genetics of autism is ... spontaneous alterations in the genetic material during meiosis that delete or duplicate genetic material. Sporadic (non- ...
*  Phage display
Many genetic sequences are expressed in a bacteriophage library in the form of fusions with the bacteriophage coat protein, so ... Gommans WM, Haisma HJ, Rots MG (December 2005). "Engineering zinc finger protein transcription factors: the therapeutic ... The protein displayed corresponds to the genetic sequence within the phage. This phage-display library is added to the dish and ... Danner S, Belasco JG (November 2001). "T7 phage display: a novel genetic selection system for cloning RNA-binding proteins from ...