Computational Biology of Transcription Factor Binding. Methods in Molecular Biology. Vol. 674. pp. 57-83. doi:10.1007/978-1- ...
DBD database of predicted transcription factors Kummerfeld SK, Teichmann SA (January 2006). "DBD: a transcription factor ... For example, proteins that regulate transcription by binding DNA are called transcription factors. The final output of most ... In transcription factors these domains are often found in arrays (usually separated by short linker sequences) and adjacent ... Uses a curated set of DNA-binding domains to predict transcription factors in all completely sequenced genomes Table of DNA- ...
... helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription". The ... Transcription factor 21 (TCF21), also known as pod-1, capsuling, or epicardin, is a protein that in humans is encoded by the ... TCF21 encodes a transcription factor of the basic helix-loop-helix (bHLH) family, which manages cell-fate specification, ... "Entrez Gene: TCF21 transcription factor 21". "BioGPS - your Gene Portal System". biogps.org. Retrieved 11 October 2016. Acharya ...
... is a transcription elongation factor. It was first identified during a search for RNA polymerase II-associated elongation ... Liu Z, Zhou Z, Chen G, Bao S (Feb 2007). "A putative transcriptional elongation factor hIws1 is essential for mammalian cell ... Liu Z, Zhou Z, Chen G, Bao S (Feb 2007). "A putative transcriptional elongation factor hIws1 is essential for mammalian cell ... to RNAPII during transcription elongation and is required for H3K36 trimethylation. GRCh38: Ensembl release 89: ENSG00000163166 ...
Elongin B is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It ... Li XY, Green MR (1998). "The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor". Genes Dev. ... Bradsher JN, Jackson KW, Conaway RC, Conaway JW (1994). "RNA polymerase II transcription factor SIII. I. Identification, ... "Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog". Proc Natl Acad Sci U S A. 92 (16): ...
bHLH transcription factors are often important in development or cell activity. For one, BMAL1-Clock (also called ARNTL) is a ... In general, transcription factors (including this type) are dimeric, each with one helix containing basic amino acid residues ... The word "basic" does not refer to complexity but to the chemistry of the motif because transcription factors in general ... Neurogenins MAX C-Myc, N-Myc TCF4 (Transcription Factor 4) These proteins contain two additional PAS domains after the bHLH ...
"Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production". Journal of ... "Entrez Gene: YY1 YY1 transcription factor". Weintraub AS, Li CH, Zamudio AV, Sigova AA, Hannett NM, Day DS, et al. (December ... Becker KG, Swergold GD, Ozato K, Thayer RE (October 1993). "Binding of the ubiquitous nuclear transcription factor YY1 to a cis ... Zhu W, Lossie AC, Camper SA, Gumucio DL (April 1994). "Chromosomal localization of the transcription factor YY1 in the mouse ...
Some transcription factors bind as dimers. Therefore, their binding sites may consist of two conserved regions, separated by a ... These transcription factor binding sites (TFBS), or regulatory motifs, have proven hard to identify, primarily because they are ... Phylogenetic footprinting is a technique used to identify transcription factor binding sites (TFBS) within a non-coding region ... Phylogenetic footprinting relies upon two major concepts: The function and DNA binding preferences of transcription factors are ...
... transcription factor genes MN1 and PER1; d) homeobox protein transcription factor CDX2; e) Protein tyrosine phosphatase ... The human ETV6 protein is a member of the ETS transcription factor family; however, it more often acts to inhibit than ... It binds to and thereby inhibits FLI1, another member of the ETS transcription factor family, which is active in promoting the ... ETV6 (i.e. translocation-Ets-leukemia virus) protein is a transcription factor that in humans is encoded by the ETV6 ( ...
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF ... Sharrocks AD, Brown AL, Ling Y, Yates PR (1998). "The ETS-domain transcription factor family". Int. J. Biochem. Cell Biol. 29 ( ... 1994). "Net, a new ets transcription factor that is activated by Ras". Genes Dev. 8 (13): 1502-13. doi:10.1101/gad.8.13.1502. ... Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. ...
Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific for the thyroid, lung, and ... G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcription". The Journal of ... containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription ... NK2 homeobox 1 (NKX2-1), also known as thyroid transcription factor 1 (TTF-1), is a protein which in humans is encoded by the ...
In the transcription factor ETS wHTH folds into a helix-turn-helix motif on a four-stranded anti-parallel beta-sheet scaffold ... These include the LuxR-type DNA-binding HTH domain found in bacterial transcription factors and the helix-turn-helix motif ... Sharrocks AD, Brown AL, Ling Y, Yates PR (December 1997). "The ETS-domain transcription factor family". The International ... "A phylogenomic analysis of bacterial helix-turn-helix transcription factors". FEMS Microbiology Reviews. 33 (2): 411-29. doi: ...
BOB1 is a transcriptional coactivator (i.e. a protein that controls the activity of transcription factors) which is expressed ... POU domain POU domain class 2 transcription factors: POU2F1, POU2F2, POU2F3 GRCh38: Ensembl release 89: ENSG00000110777 - ... "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Mol. Cell. Biol. 18 ( ... "New transcription factors in diagnostic hematopathology". Advances in Anatomic Pathology. 14 (1): 25-35. doi:10.1097/PAP. ...
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of ... Janknecht R, Hunter T (1997). "Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen- ... Sharrocks AD, Brown AL, Ling Y, Yates PR (1998). "The ETS-domain transcription factor family". Int. J. Biochem. Cell Biol. 29 ( ... Wasylyk B, Hagman J, Gutierrez-Hartmann A (1998). "Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling ...
... and repressors are transcription factors composed of a zinc finger protein domain and any of a variety of transcription-factor ... Artificial transcription factors with engineered zinc finger arrays have been used in numerous scientific studies, and an ... The majority of engineered zinc finger arrays are based on the zinc finger domain of the murine transcription factor Zif268, ... Gene therapy Zinc finger nuclease Zinc finger protein Zinc finger protein transcription factor Gommans WM, Haisma HJ, Rots MG ( ...
Grummt I (Apr 2006). "Actin and myosin as transcription factors". Current Opinion in Genetics & Development. 16 (2): 191-196. ... Transcription - Actin is involved in chromatin reorganization, transcription initiation and interaction with the transcription ... In Pol I transcription, actin and myosin (MYO1C, which binds DNA) act as a molecular motor. For Pol II transcription, β-actin ... Nucleation promoting factors bind two free G-actin molecules, then recruit and activate the Arp2/3 complex. The activated Arp2/ ...
... acts as a transcriptional coregulator and has no effect on transcription alone. When in complex with transcription factor ... such as the four members of the TEAD transcription factor family, Paired box gene 3 (PAX3), and Runt related transcription ... Dai C, Chen X, Li J, Comish P, Kang R, Tang D (September 2020). "Transcription factors in ferroptotic cell death". Cancer Gene ... YAP and TAZ cooperate with transcription factors to promote tissue formation. WWTR1 (TAZ) interacts with a variety of ...
Transcription factor EB is a protein that in humans is encoded by the TFEB gene. TFEB is a master gene for lysosomal biogenesis ... "Entrez Gene: TFEB transcription factor EB". Sardiello M, Palmieri M, di Ronza A, Medina DL, Valenza M, Gennarino VA, Di Malta C ... It encodes a transcription factor that coordinates expression of lysosomal hydrolases, membrane proteins and genes involved in ... Verastegui C, Bertolotto C, Bille K, Abbe P, Ortonne JP, Ballotti R (Mar 2000). "TFE3, a transcription factor homologous to ...
Nuclear factor 1, a transcription factor. NF-1, a variant of the AA-12 machine gun rechambered for 7.62 NATO ammunition. NF1 ( ...
Elongin C is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It ... "Entrez Gene: TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)". Rual JF, Venkatesan K, Hao T, ... Bradsher JN, Jackson KW, Conaway RC, Conaway JW (1994). "RNA polymerase II transcription factor SIII. I. Identification, ... "A human cDNA encoding the small subunit of RNA polymerase II transcription factor SIII". Gene. 150 (2): 413-4. doi:10.1016/0378 ...
Transcription factor Riva, Alberto (Jan 2012). "The MAPPER2 Database: a multi-genome catalog of putative transcription factor ... Mapper(2) is a database of transcription factor binding sites in multiple genomes. ...
These factors include: The transcription factor p63, which prevents epidermal stem cells from differentiating into ... Cathepsin E. TALE homeodomain transcription factors. Hydrocortisone. Since keratinocyte differentiation inhibits keratinocyte ... Epidermal growth factor. Transforming growth factor alpha. Cholera toxin. Within the epidermis keratinocytes are associated ... The roles of transforming growth factor-alpha and epidermal growth factor". Cell. 50 (7): 1131-7. doi:10.1016/0092-8674(87) ...
Nishida, K.; Frith, M. C.; Nakai, K. (23 December 2008). "Pseudocounts for transcription factor binding sites". Nucleic Acids ... 2003). "MATCHTM: a tool for searching transcription factor binding sites in DNA sequences". Nucleic Acids Research. 31 (13): ...
Beerli RR, Barbas CF (2002). "Engineering polydactyl zinc-finger transcription factors". Nat. Biotechnol. 20 (2): 135-41. doi: ... family DNA sequences and their use in the construction of artificial transcription factors". J. Biol. Chem. 280 (42): 35588-97 ...
... primary transcription factors, i.e., transcription factors that are present in cells in an inactive state and do not require ... Escárcega RO, Fuentes-Alexandro S, García-Carrasco M, Gatica A, Zamora A (March 2007). "The transcription factor nuclear factor ... Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a protein complex that controls transcription of DNA ... This is either due to mutations in genes encoding the NF-κB transcription factors themselves or in genes that control NF-κB ...
E74-like factor 5 (ets domain transcription factor), is a gene found in both mice and humans. In humans it is also called ESE2 ... "Entrez Gene: ELF5 E74-like factor 5 (ets domain transcription factor)". Piggin CL, Roden DL, Gallego-Ortega D, Lee HJ, Oakes SR ... Zhou J, Ng AY, Tymms MJ, Jermiin LS, Seth AK, Thomas RS, Kola I (Nov 1998). "A novel transcription factor, ELF5, belongs to the ... The protein encoded by this gene is a member of an epithelium-specific subclass of the ETS transcription factor family. In ...
"Transcription factors" table according to the Transfac database. Database of Arabidopsis Transcription Factors B3 Archived 2019 ... there are three main families of transcription factors that contain B3 domain: ARF (Auxin Response Factors) ABI3 (ABscisic acid ... The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors (≥40 species) (Pfam ... Tiwari SB, Hagen G, Guilfoyle TJ (2003). "The Roles of Auxin Response Factor Domains in Auxin-Responsive Transcription". Plant ...
2002). "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to ... "Entrez Gene: TFEC transcription factor EC". Zhao GQ, Zhao Q, Zhou X, et al. (1993). "TFEC, a basic helix-loop-helix protein, ... Transcription factor EC is a protein that in humans is encoded by the TFEC gene. GRCh38: Ensembl release 89: ENSG00000105967 - ... 1999). "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization". Development. 125 (23): 4607-16. doi ...
One important transcription factor is AbPf2. It regulates 6 of the 139 genes encoding small secretion proteins and may have a ... Currently, research is being done to identify the gene(s) responsible for encoding a transcription factor, Bdtf1, important for ... Pathogenesis is affected by factors such as: temperature, humidity, pH, reactive oxidation species, host defense molecules. Out ...
Grunert M, Dorn C, Rickert-Sperling S (2016). "Cardiac Transcription Factors and Regulatory Networks". Congenital Heart ...