"Molecular determinants of the cell-cycle regulated Mcm1p-Fkh2p transcription factor complex". Nucleic Acids Research. 31 (9): ... or cell cycle dependent. 40% of the genes found to be regulated by Bck2 were also targets of regulation by Mcm1. Mcm1 activates ... "Bck2 is a phase-independent activator of cell cycle-regulated genes in yeast". Cell Cycle. 8 (2): 239-52. doi:10.4161/cc.8.2. ... Overexpression of Bck2 in Swi6-null cells resulted in changes in expression of genes known to be regulators of the cell cycle, ...

Myslinski E, Gérard MA, Krol A, Carbon P (2007). "Transcription of the human cell cycle regulated BUB1B gene requires hStaf/ ... SphI postoctamer homology-binding factor/selenocysteine tRNA gene transcription activating factor, stimulates transcription of ... 2007). "ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair ... Gérard MA, Krol A, Carbon P (2007). "Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene". Gene ...

... and cell cycle-regulated transcription factor E2F". Molecular and Cellular Biology. 16 (4): 1659-67. doi:10.1128/mcb.16.4.1659 ... "O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation". Cell. 55 (1): ... "Entrez Gene: Sp1 transcription factor". Li, Lin; He, Shihua; Sun, Jian-Min; Davie, James R (2004-08-01). "Gene regulation by ... Sp1 and GATA factors are necessary for basal transcription in endothelial cells". The Journal of Biological Chemistry. 270 (25 ...

"Role of Polycomb Repressive Complex 2 in Regulation of Human Transcription Factor Gene Expression" (PDF). Brown, Jay C. ( ... "Cell cycle dependent exposure of a high molecular weight protein on the surface of mouse L cells". Biochimica et Biophysica ... of Polycomb Repressive Complex 2 genes of tissue-targeted transcription factor genes in the repression of transcription factor ... Brown's current research revolves around the control of human gene expression and Organization of transcription factor binding ...

Chen D, Ma H, Hong H, Koh SS, Huang SM, Schurter BT, Aswad DW, Stallcup MR (June 1999). "Regulation of transcription by a ... delays cell cycle transition and/or proliferation. In contrast, methylation of histone residues H3K4, H3K36, and H3K79 is ... however they may be a contributing factor. For example, down-regulation of methylation of lysine 9 on histone 3 (H3K9me3) has ... stem cell maturation, cell lineage development, genetic imprinting, DNA methylation, and cell mitosis. The class of lysine- ...

Mitogen Signaling Growth factors (e.g., PDGF, FGF, and EGF) regulate entry of cells into the cell cycle and progression to the ... Sustained mitogen signaling promotes cell cycle entry largely through regulation of the G1 cyclins (cyclin D1-3) and their ... such as the transcription factor serum-response factor (SRF), resulting in expression of immediate early genes-notably the ... is a cell cycle checkpoint in the G1 phase of the animal cell cycle at which the cell becomes "committed" to the cell cycle, ...

Cullin-RING E3 ubiquitin ligases are involved in many cellular processes responsible for cell cycle regulation, stress response ... Furukawa M, Xiong Y (January 2005). "BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the ... "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family". Cell. 85 (6): 829-39. doi:10.1016/ ... This protein is a transcription factor regulating the expression of some detoxification and antioxidant enzymes. Another ...

Ljungman M (September 2007). "The transcription stress response". Cell Cycle. 6 (18): 2252-2257. doi:10.4161/cc.6.18.4751. PMID ... or cancer cells. Example of these growth factors are angiopoietin 1 (ANG1), ANG 2, basic fibroblast growth factor (bFGF), ... and Rho related to cell survival, migration and regulation of the actin cytoskeleton. The mTORC1 signaling cascade is activated ... A G0-G1 cell-cycle blockage can be the consequence of inactivation of mTOR in hypoxia-activated pericytes and endothelial cells ...

"Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm". Cell. 140 (3): 306- ... These proteins take part in RNA transcription and gene regulation in the nucleoplasm. Proteins located in the nucleoplasm are ... Importantly, the nucleoplasm contains co-factors and co-enzymes, including acetyl-CoA, which plays a vital role in the citric ... The cytoplasm is also found in all known cells while nucleoplasm is only found in eukaryotic cells, as prokaryotic cells lack a ...

... putative Rb-binding domains have also been found on HDAC10 which shows it may have roles in the regulation of the cell cycle. ... the myogenic transcription factor MEF2 which an essential role in muscle differentiation as a DNA binding transcription factor ... and transcription factors that process and "read" the modification codes. The outcome can be activation of transcription or ... Structural analysis of transcription factors has shown that highly conserved bromodomains are essential for protein to bind to ...

... which contribute to transcription repression and cell cycle regulation, and which have a role in the cellular response to DNA ... and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor ... and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor ... 1999). "Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA ...

Fujita M, Yamada C, Goto H, Yokoyama N, Kuzushima K, Inagaki M, Tsurumi T (1999). "Cell cycle regulation of human CDC6 protein ... assembly/targeting factor interacts physically with the MCM7 DNA licensing factor". FEBS Lett. 484 (1): 17-21. doi:10.1016/ ... "Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation ... Fujita M, Yamada C, Goto H, Yokoyama N, Kuzushima K, Inagaki M, Tsurumi T (September 1999). "Cell cycle regulation of human ...

... needed in cell cycle regulation, and this can cause a cell to become cancerous (He et al., 2005). MicroRNAs and genes involved ... It was reported that luciferase expression, which was driven by the 3'UTRs of integrin alpha 3 (ITGA3) or transcription factor ... which normally stop cell growth in the G1 phase of cell division. When this happens, there is no regulation in the cell and it ... This silencing of genes can be dangerous to cells, especially when the genes silenced are active in maintaining the cell cycle ...

Casein kinase 2 can play a role in cell cycle regulation, DNA repair, and necessary for cell survival; down-regulation of ... The below selected transcription factors were chosen based on conservation among species first, and then further parsed for ... Genes in this cytogenetic region, including SMIM19 gene, are also prone to down regulation in common breast tumors and cell ... Dendritic Cells- Specific Transmembrane Protein (DC-STAMP) is a seven- pass transmembrane protein specifically found in ...

Zhao RY, Elder RT (2005). "Viral infections and cell cycle G2/M regulation". Cell Res. 15 (3): 143-9. doi:10.1038/sj.cr.7290279 ... and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation". Mol ... "Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production". ... cell cycle arrest: Vpr interferes with cell cycle signaling cascades by interacting with the B subunit of serine/threonine ...

Bosu DR, Kipreos ET (2008). "Cullin-RING ubiquitin ligases: global regulation and activation cycles". Cell Division. 3: 7. doi: ... Recent reports show that IMiDs bind to CRL4CRBN and promote the degradation of IKZF1 and IKZF3 transcription factors, which are ... "HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase". Cell Cycle. 6 (2): ... accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1". ...

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone ... This protein possesses histone deacetylase activity and represses transcription. It retracts the cilium of the cell, which is ... Gao YS, Hubbert CC, Lu J, Lee YS, Lee JY, Yao TP (December 2007). "Histone deacetylase 6 regulates growth factor-induced actin ... As a result the enzyme encourages cancer cell metastasis. HDAC6 affects transcription and translation by regulating heat-shock ...

Regulation of p16 is complex and involves the interaction of several transcription factors, as well as several proteins ... is a protein that slows cell division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby ... methylation can lead to the recruitment of transcription factors that repress transcription. Both mechanisms cause the same end ... p16 is an inhibitor of cyclin-dependent kinases (CDK). It slows down the cell cycle by prohibiting progression from G1 phase to ...

... and cell cycle-regulated transcription factor E2F". Mol. Cell. Biol. 16 (4): 1659-67. doi:10.1128/mcb.16.4.1659. PMC 231152. ... Crowley TE, Kaine EM, Yoshida M, Nandi A, Wolgemuth DJ (2003). "Reproductive cycle regulation of nuclear import, euchromatic ... E2F2 E2F transcription factor 2". Crowley TE, Kaine EM, Yoshida M, Nandi A, Wolgemuth DJ (August 2002). "Reproductive cycle ... a novel protein with the biochemical properties of transcription factor E2F". Mol Cell Biol. 13 (12): 7802-12. doi:10.1128/MCB. ...

... and cell cycle-regulated transcription factor E2F". Mol. Cell. Biol. 16 (4): 1659-67. doi:10.1128/mcb.16.4.1659. PMC 231152. ... "Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". J. Mol. ... "Functions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins". ... This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell ...

The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... It also regulates the cell cycle and arrests cell growth by activating a regulator of the cell cycle, p21. Under severe DNA ... Protein N-terminal acetylation has also been proved to relate with cell cycle regulation and apoptosis with protein knockdown ... Ectopic expression of hNaa10p increased cell proliferation and up regulation of gene involved in cell survival proliferation ...

Joaquin M, Watson RJ (Nov 2003). "The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase ... The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is ... In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. ... Verona R, Moberg K, Estes S, Starz M, Vernon JP, Lees JA (Dec 1997). "E2F activity is regulated by cell cycle-dependent changes ...

Originally identified as a RNA-binding protein involved in cell cycle regulation, CHTOP contains two UBMs like those in ALYREF ... During transcription elongation, the THO complex follows RNA polymerase II and interacts with transcription factors along the ... end processing factors/transcription termination factors, which load DEAD-box RNA helicase UAP56 and RNA export adapter ALYREF ... At the end of transcription, after the 3'-end of mRNA is formed and the mRNA is released from transcription site, the mRNA is ...

... it is expected for cell cycle-regulatory proteins to be under tight regulation. The level of cyclins, as the name suggests, is ... VHL complex targets a member of the hypoxia-inducible transcription factor family (HIF) for degradation by interacting with the ... forming a family of cell cycle regulators which control cell cycle progression through the G1 phase. Low level of p27Kip-1 ... Ubiquitination, or ubiquitin conjugation to proteins, is a crucial process for cell cycle progression and cell proliferation ...

JDP2 induces cell cycle arrest through cyclin D, p53, and cyclin A transcription, by increasing JUNB, JUND, and Fra2, and by ... April 2006). "Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2". Nature Structural & ... "Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in ... July 2018). "JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia". The Journal of Experimental ...

... and regulation of Ace2p (transcription factor) and cellular morphogenesis (RAM) signalling networks. Overall, the integration ... regulatory networks allows for the cell wall degrading chitinase to function dependent on the cell's stage in the cell cycle ... As these types of chitinases are important in cell division, there must be tight regulation and activation. Specifically, Cts1 ... In Saccharomyces cerevisiae and the regulation of ScCts1p (S. cerevisiae chitinase 1), one of the chitinases involved in cell ...

"Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of ... "Transcription factor MIZ-1 is regulated via microtubule association". Molecular Cell. 8 (2): 339-49. doi:10.1016/S1097-2765(01) ... "Negative regulation of the mammalian UV response by Myc through association with Miz-1". Molecular Cell. 10 (3): 509-21. doi: ... "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of ...

Ohtani K, DeGregori J, Nevins JR (1996). "Regulation of the cyclin E gene by transcription factor E2F1". Proc. Natl. Acad. Sci ... which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle ... This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S ... Mayer C, Zhao J, Yuan X, Grummt I (February 2004). "mTOR-dependent activation of the transcription factor TIF-IA links rRNA ...

... the cell cycle has a complex circuitry of regulation and the role of CDK6 might be more important in certain cell types than in ... like mitogens and growth factors. CDK6 is involved in a positive feedback loop that activates transcription factors through a ... Kozar K, Sicinski P (March 2005). "Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes". Cell Cycle. ... Grossel MJ, Hinds PW (February 2006). "From cell cycle to differentiation: an expanding role for cdk6". Cell Cycle. Informa UK ...

It is not yet clear what advantage this has on the cancer cells, but given FADDs roles in cell cycle regulation and cell ... Activation of nuclear factor kappa B (NFκB) signalling leads to transcription of various proinflammatory cytokines as well as ... "Emerging roles for the death adaptor FADD in death receptor avidity and cell cycle regulation". Cell Cycle. 5 (20): 2332-2338. ... which leads to cell cycle arrest. FADD phosphorylated at Ser194 makes cells more sensitive to cell cycle arrest induced by ...

"The steady state levels and structure of the U7 snRNP are constant during the human cell cycle: lack of cell cycle regulation ... "U7 snRNA acts as a transcriptional regulator interacting with an inverted CCAAT sequence-binding transcription factor NF-Y". ... Hoffmann I, Birnstiel ML (1990). "Cell cycle-dependent regulation of histone precursor mRNA processing by modulation of U7 ... and U12 small nuclear RNA genes in interphase HeLa cells but not with U6 and U7 genes". Mol Biol Cell. 10 (5): 1653-63. doi: ...

Hirao A, Arai F, Suda T (December 2004). "Regulation of cell cycle in hematopoietic stem cells by the niche". Cell Cycle. 3 (12 ... "Transcription factor Stat5 is an early marker of differentiation of murine embryonic stem cells". Differentiation. 62 (5): 213- ... Stem cell markers are genes and their protein products used by scientists to isolate and identify stem cells. Stem cells can ... 2005). "Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors". Stem Cells. 23 (6 ...

Lam EW, Bennett JD, Watson RJ (July 1995). "Cell-cycle regulation of human B-myb transcription". Gene. 160 (2): 277-81. doi: ... Saville MK, Watson RJ (November 1998). "The cell-cycle regulated transcription factor B-Myb is phosphorylated by cyclin A/Cdk2 ... Joaquin M, Watson RJ (November 2003). "The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase ... a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded ...

Satyanarayana A, Kaldis P (August 2009). "Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse ... This allows E2F transcription factors to express genes that promote entry into S phase where DNA is replicated prior to ... This suggests that Cdk2 is non-essential for the cell cycle of healthy cells, but essential for meiosis and reproduction. Cells ... Kaldis P, Aleem E (November 2005). "Cell cycle sibling rivalry: Cdc2 vs. Cdk2". Cell Cycle. 4 (11): 1491-4. doi:10.4161/cc.4.11 ...

"Transcription factor binding sites for GXP_149843". "miRDB - MicroRNA Target Prediction Database". www.mirdb.org. Retrieved May ... While the function of TMEM128 is poorly understood, it interacts with several proteins associated with the cell cycle, signal ... In terms of protein regulation, TMEM128 contains many different post-translational domains including glycation, phosphorylation ... TMEM128 sequence also contains many binding sites for various transcription factors, including TATA box, CCAAT binding protein ...