There is no clear first-line tocolytic agent. Current evidence suggests that first line treatment with β2 agonists, calcium ... The future direction of the development of tocolytics agents should be directed toward better efficacy in intentionally ... Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm ... Depending on the tocolytic used, the pregnant woman or fetus may require monitoring (e.g., blood pressure monitoring when ...
Tsatsaris, Vassilis; Cabrol, Dominique; Carbonne, Bruno (2004). "Pharmacokinetics of tocolytic agents". Clinical ... Tocolytics delay labour by inhibiting contractions of the uterine muscles that progress labour. The most widely used tocolytics ... The goal of administering tocolytics is not to delay delivery to the point that the child can be delivered at term, but instead ... The WHO does not recommend the use of antispasmodic agents for prevention of delay in labour. For years an episiotomy was ...
In the past, alcohol was used as a common tocolytic agent. Tocolytic agents are drugs that are used to prevent preterm labor ( ... Not only is ethanol worse than other beta-mimetic drugs (type of tocolytic agents) at postponing birth, it also leads to a ...
Giorgino FL, Egan CG (2010). "Use of isoxsuprine hydrochloride as a tocolytic agent in the treatment of preterm labour: a ... Falkay G, Kovács L (1986). "Affinity of tocolytic agents on human placental and myometrial beta-adrenergic receptors". Journal ... Isoxsuprine is used in humans for treatment of premature labor, i.e. a tocolytic, and as a vasodilator for the treatment of ...
The tocolytic agent atosiban (Tractocile) acts as an antagonist of oxytocin receptors. It is registered in many countries for ... It has largely replaced ergometrine as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is ...
... has been used frequently as a tocolytic (agent that delays premature labor). A Cochrane review has concluded that it ...
There is no need for chronic administration of tocolytic agents since postoperative uterine contractions are barely ever ...
... is also used in some countries (such as Russia and Switzerland) as a tocolytic agent (i.e., labor suppressant), ... When used as a tocolytic, hexoprenaline is contraindicated in: Hyperthyroidism Cardiovascular diseases, e.g. cardiac ... Tocolytics, Phenylethanolamines, All stub articles, Respiratory system drug stubs). ...
... is an effective tocolytic agent, able to delay premature labor by reducing uterine contractions through inhibition ... Hart FD, Boardman PL (October 1963). "Indomethacin: A New Non-steroid Anti-inflammatory Agent". British Medical Journal. 2 ( ... 550-. ISBN 978-3-88763-075-1. Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties ... Antigout agents, Carboxamides, Chloroarenes, Hepatotoxins, Indole ethers at the benzene ring, Nonsteroidal anti-inflammatory ...
While the use of tocolytic agents or the development of preeclampsia (toxemia of pregnancy) and pregnancy-induced hypertension ... the majority of women have developed PPCM who neither received tocolytics nor had preeclampsia nor PIH. When looking at the ...
Niebyl specializes in high risk obstetrics, focusing on medical drug use in pregnancy, tocolytic agents for preterm labor, ... Drugs and Environmental Agents in Pregnancy and Lactation: Embryology, Teratology, Epidemiology (2012, Obstetrics: Normal and ...
... but has been shown to be an ineffective tocolytic agent. More common side effects from magnesium include upset stomach and ... As a bronchodilator after beta-agonist and anticholinergic agents have been tried, e.g. in severe exacerbations of asthma. ...
... a tocolytic agent, and as an anticonvulsant. It also may be used as laxative. In agriculture, magnesium sulfate is used to ...
... Agents and Tocolytics", Clinical Pharmacology During Pregnancy, Academic Press, pp. 307-330, ISBN 978-0-12- ...
It is classified by the World Anti-Doping Agency as an anabolic agent, not as a β2 agonist. Clenbuterol is prescribed for ... It is commonly used for smooth muscle-relaxant properties as a bronchodilator and tocolytic. ... As of 2011, the World Anti-Doping Agency (WADA) listed Clenbuterol as an anabolic agent, despite the fact there is no evidence ... Likewise, Duchaine erred in promoting the drug Gamma-hydroxybutyric acid (GHB) as an anabolic agent, and served time for the ...
Antiarrhythmic agents, Antidepressants, Diuretics, Sedatives, Food additives, Hypnotics, Antispasmodics, Tocolytics, ... Magnesium citrate is used as a laxative agent. It is not recommended for use in children and infants two years of age or less. ...
While preferred over agents such as atosiban and ritodrine, its role has largely been replaced by the calcium channel blocker ... Intravenous salbutamol can be used as a tocolytic to relax the uterine smooth muscle to delay premature labor. ...
Oxytocin, a uterotonic agent, can be administered to augment labor. Cesarean section is also commonly considered when the ... If the abnormal fetal heart rate persists, and uterine tachysystole continues, tocolytic remedies, such as terbutaline, may be ... oxytocin as a labor augmenting agent may be resumed. The persistence of an abnormal fetal heart rate may also indicate that a ...
It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. It was developed by Ferring ... to nifedipine did not deliver and did not require an alternate agent at 48 hours, respectively (p=.03). Atosiban has fewer ... de Heus R, Mulder EJ, Derks JB, Visser GH (June 2009). "The effects of the tocolytics atosiban and nifedipine on fetal ... ritodrine in 128 women shows a significantly better tocolytic efficacy after 7 days in the atosiban group than in the ritodrine ...
... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tocolytic agents MeSH D27.505.954.796 - respiratory system agents MeSH D27.505.954.796.050 - anti-asthmatic agents MeSH D27.505 ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Magnesium sulfate was once used as a tocolytic, but meta-analyses have failed to support it as an anti-contraction medication. ... Magnesium sulfate may be used as an antiarrhythmic agent for torsades de pointes in cardiac arrest under the ECC guidelines and ... Magnesium sulfate may be used as bronchodilator after beta-agonist and anticholinergic agents have been tried, e.g. in severe ... Lewis DF (September 2005). "Magnesium sulfate: the first-line tocolytic". Obstetrics and Gynecology Clinics of North America. ...
... is used as a cardioprotective agent in people with high blood potassium levels, with one alternative being ... other tocolytics are now used instead due to better efficacy and side effect profiles).[citation needed] Excess magnesium ...
From the 1960s to the 1980s, alcohol was commonly used as a tocolytic, a method to stop preterm labor. The method originated ... Smith named FAS after the causal agent of the symptoms. He reasoned that doing so would encourage prevention, believing that if ... he suggested the causal agent to be alcohol use. This contradicted the predominating belief at the time that heredity caused ...
Geller J, Fruchtman B, Newman H, Roberts T, Silva R (February 1967). "Effect of progestational agents on carcinoma of the ... and tocolytic efficacy". Reproductive Sciences. 16 (11): 1052-61. doi:10.1177/1933719109340926. PMID 19602723. S2CID 6856556. ... Hall NR (June 2011). "What agent should be used to prevent recurrent preterm birth: 17-P or natural progesterone?". Obstetrics ... In the group of new parenteral progestational agents, three substances developed by Karl Junkmann1,2 are the most outstanding ...
In functional expression studies, TAS2R14 responds to (−)-α-thujone, the primary neurotoxic agent in absinthe, and picrotoxin, ... September 2017). "Bitter taste receptors as targets for tocolytics in preterm labor therapy". FASEB Journal. 31 (9): 4037-4052 ...
Even if agents such as calcium or antioxidants were able to reduce preeclampsia, a resulting decrease in preterm birth was not ... Haas DM, Caldwell DM, Kirkpatrick P, McIntosh JJ, Welton NJ (October 2012). "Tocolytic therapy for preterm delivery: systematic ... A number of agents have been studied for the secondary prevention of indicated preterm birth. Trials using low-dose aspirin, ... presumably as these agents inhibit production of proinflammatory cytokines. A randomized trial showed a significant decline in ...