*  Breast cancer classification
Carcinoma in situ is proliferation of cancer cells within the epithelial tissue without invasion of the surrounding tissue. In ... Lower-grade tumors, with a more favorable prognosis, can be treated less aggressively, and have a better survival rate. Higher- ... The test is run on formalin fixed, paraffin-embedded tissue. MammaPrint traditionally used rapidly frozen tissue but a room ... to form tissues such as ducts, so the tissue structures become less orderly. Note: The overall appearance of the tumor has to ...
*  Metastatic breast cancer
Cancer cells can then use the proteinase to facilitate tissue invasion, which requires the degradation of connective tissue ... Mean survival from diagnosis of a brain metastasis varies between studies, ranging from 2 to 16 months (depending on ... Extravasation to a distant site : The cell then invades into the BM of the target tissue. Proliferation of the cancer cell at ... Whole-brain radiation may provide a median survival of 4 to 5 months, which can be further extended by months with stereotactic ...
*  Breast cancer management
Additional surgery may be necessary if the removed tissue does not have clear margins, sometimes requiring removal of part of ... resulting in fewer side effects while achieving the same 10-year survival as its predecessor. The sentinel lymph node is the ... Standard practice requires the surgeon to establish that the tissue removed in the operation has margins clear of cancer, ... tumor is large relative to the size of the breast The patient has had scleroderma or another disease of the connective tissue, ...
*  Frostbite
The effect of hyperbaric oxygenation on tissue survival". Cryobiology. 7 (1): 1-8. doi:10.1016/0011-2240(70)90038-6. PMID ... The faster tissue is thawed, the less tissue damage occurs. According the Handford and colleagues, "The Wilderness Medical ... Scar tissue forms when fibroblasts replace the dead cells. Rewarming causes tissue damage through reperfusion injury, which ... C are required to form ice crystals in the tissues. The process of freezing causes ice crystals to form in the tissue, which in ...
*  Magnetic resonance angiography
BOLD can also be used in stroke imaging in order to assess the viability of tissue survival. MRA techniques in general are ... Static tissues such as muscle or bone will subtract out, however moving tissues such as blood will acquire a different phase ... Differences in tissue signals, can also be used for MRA. This method is based on the different signal properties of blood ... These methods are based on the differences of T1, T2 and chemical shift of the different tissues of the voxel. A notable ...
*  Cells Alive System
They also are claimed to increase tissue survival without having its water replaced by cryogenically compatible fluids; whether ...
*  Remote ischemic conditioning
RIC increased tissue survival after one month and reduced the risk of infarction in high-risk tissue. Two randomized trials of ... in the tissue. This "conditioning" activates the body's natural protective physiology against reperfusion injury and the tissue ... The RIC stimulus can be applied to different tissues in the body. Either the upper limb (arm) or the lower limb (leg) may be ... Gerd Heusch's lab showed that propofol abolishes the phosphorylation of STAT5, a key survival molecule that is activated by RIC ...
*  Laminin
... maintenance of tissue phenotype, and promotion of tissue survival. Some of these biological functions of laminin have been ... Laminin is vital for the maintenance and survival of tissues. Defective laminins can cause muscles to form improperly, leading ... 2002). Connective tissue and its heritable disorders: molecular, genetic, and medical aspects (2nd ed.). New York: Wiley-Liss. ... The long arm is capable of binding to cells, which helps anchor organized tissue cells to the membrane. The laminin family of ...
*  Necroptosis
... improves tissue survival primarily by inhibiting necrotic cell death, rather than its additional function as an ... In solid-organ transplantation, ischemia-reperfusion injury can occur when blood returns to tissue for the first time in the ... Necroptosis has been implicated in the pathology of many types of acute tissue damage, including myocardinal infarction, stroke ... A major contributor to tissue damage results from activation of regulated necroptosis, which could include contributions from ...
*  International Journal of Surgery
"Preoperative shock wave treatment enhances ischemic tissue survival, blood flow and angiogenesis in a rat skin flap model" 2011 ...
*  Actinomyces radicidentis
Nair, P.N.R.; Brundin, Malin; Sundqvist, Göran; Sjögren, Ulf (2008). "Building biofilms in vital host tissues: a survival ... held together by embedding in an extracellular matrix in host tissues. Like other pathogenic Actinomyces, by collectively ...
*  Siderophore
Pathogenic bacteria and fungi have developed the means of survival in animal tissue. They may invade the gastro-intestinal ... There are four major ecological habitats: soil and surface water, marine water, plant tissue (pathogens) and animal tissue ( ... Bacteria frequently infect plants by gaining entry to the tissue via the stomata. Having entered the plant they spread and ...
*  TNFSF18
It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in ... 2006). "Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates ...
*  Cardiomyoplasty
... impact of mechanical forces onto cell survival and tissue hypoxia. Furthermore, lack of cellular electrochemical coupling can ... and improve biological tissues. Research efforts in tissue engineering have been ongoing and it is emerging as one of the key ... cell signaling agents to induce the regeneration of an organ or damaged tissue. In an ideal scenario, regenerated tissue would ... Subcutaneous adipose tissue is also a source of mesenchymal stem cells and have demonstrated positive outcomes in terms of ...
*  Ibrutinib
"The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro ... Additionally, ibrutinib inhibited proliferation of CLL cells in vitro, effectively blocking survival signals provided ... and also prevent CLL cells from responding to survival stimuli provided by the microenvironment. This also leads to a reduction ... suggesting that the drug might have direct effects on cell homing or migration to factors in tissue microenvironments. Both ...
*  Testicular immunology
... survival of tissue transplanted into the testis, or testicular tissue transplanted elsewhere. Evidence includes the tolerance ... Oatley JM, de Avila DM, Reeves JJ, McLean DJ (2004). "Testis tissue explant culture supports survival and proliferation of ... Niemi M, Sharpe RM, Brown WR (1986). "Macrophages in the interstitial tissue of the rat testis". Cell Tissue Res. 243 (2): 337- ... primate testes fail to support grafts of monkey thyroid tissue. Human testis tissue transplanted into the mouse elicited an ...
*  StemRad
The human tissue endowed with the most regenerative potential is bone marrow. This tissue is critical for human survival, yet ... For further weight reduction, StemRad's product brings into account the natural shielding properties of human tissue, by being ... the life-limiting factor is damage sustained by the bone marrow tissue. The radiation exposure levels in a nuclear catastrophe ... life of an individual even at very high doses of gamma radiation based on the unique regenerative potential of marrow tissue. ...
*  Cryonics
... freezing in tissues that do not successfully vitrify, and reversing the cause of death. In many cases extensive tissue ... A theory for injury and survival". Crybiology. 2 (3): 99-108. doi:10.1016/s0011-2240(65)80094-3. "Patients who are frozen in ... In tissues and organs, ice crystals can also disrupt connections between cells that are necessary for organs to function. The ... Large vitrified organs tend to develop fractures during cooling, a problem worsened by the large tissue masses and very low ...
*  Osteopontin
... tissue remodeling, and cell survival". J. Clin. Invest. 107 (9): 1055-61. doi:10.1172/JCI12980. PMC 209291 . PMID 11342566. ... The prefix osteo- indicates that the protein is expressed in bone, although it is also expressed in other tissues. The suffix - ... Tissue Res. 44 Suppl 1: 33-40. doi:10.1080/03008200390152061. PMID 12952171. Christensen B, Nielsen MS, Haselmann KF, Petersen ... Singh M, Dalal S, Singh K (2014). "Osteopontin: At the cross-roads of myocyte survival and myocardial function". Life Sci. 118 ...
*  DUT (gene)
... "dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5- ... "dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5- ... could also serve as a prognostic marker for overall survival and response to chemotherapy. Similarly, DUT is significantly ...
*  Heslington Brain
... "jogged my memory of a university lecture on the rare survival of ancient brain tissue ... we gave the skull special ... First, the waterlogged, anoxic soil in which the head was buried (even though only the brain, and not the rest of the tissue, ... It had survived despite the rest of the tissue on the skull having disappeared long ago. After being extracted at York Hospital ... survived burial; only scanty traces of other tissue remain on the rest of the skull). Second, the brain had undergone unusual ...
*  Rhabdomyosarcoma
"Disease patterns and survival rate in children with metastatic soft-tissue sarcoma. A report from the Intergroup ... Rhabdomyosarcoma is the most common soft-tissue sarcoma in children as well as the third most common solid tumor in children. ... RMS can occur in almost any soft-tissue site in the body; the most common primary sites are genitourinary (24%), parameningeal ... Despite being a relatively rare cancer, it accounts for approximately 40% of all recorded soft tissue sarcomas. RMS can occur ...
*  PDGFC
Platelet-derived growth factors are important in connective tissue growth, survival and function, and consist of disulphide- ... "Nuclear localisation of endogenous SUMO-1-modified PDGF-C in human thyroid tissue and cell lines". Exp. Cell Res. 312 (6): 782- ... "Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator". J. Biol. ... of the PDGFR-α signaling pathway and has a specific role in palatogenesis and the morphogenesis of the integumentary tissue. ...
*  Eremophila resinosa
Survival rates are high for both the tissue cultured and seed-raised plants. To date, over 4,000 plants are growing and 2 ... Five clones of the species were grown by tissue culture and planted at Westonia in 2004. Seed was also collected and grown at ...
*  Ovarian follicle activation
Additionally, in vitro addition of GDF9 to human ovarian cortical tissue causes enhanced activation and follicular survival. ... GDF9 promotes follicular survival and growth as a result of dampened granulosa apoptosis and follicular atresia. As discussed ... After cryopreservation, the ovarian tissue must be placed back into the patient, in order to allow the ovary to function ... Reddy, Pradeep; Zheng, Wenjing; Liu, Kui (February 2010). "Mechanisms maintaining the dormancy and survival of mammalian ...
*  Cervical cancer
Survival rates decrease to 30-40% for women with stage III cancer and 15% or fewer of those with stage IV cancer five years ... It was not until the 1980s that HPV was identified in cervical cancer tissue. It has since been demonstrated that HPV is ... Five year survival in the United States for White women is 69% and for Black women is 57%. Regular screening has meant that ... Five-year survival rates in the United States are 68%. Outcomes, however, depend very much on how early the cancer is detected ...
*  BCL2L2
2001). "Tissue expression and subcellular localization of the pro-survival molecule Bcl-w". Cell Death Differ. 8 (5): 486-94. ... Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout ... Located on chromosome 14q11 it appears to be redundant in most tissues apart from specific examples. BCL2L2 has been shown to ... Holmgreen SP, Huang DC, Adams JM, Cory S (June 1999). "Survival activity of Bcl-2 homologs Bcl-w and A1 only partially ...