Tissue Antigens. 51 (6): 649-52. doi:10.1111/j.1399-0039.1998.tb03008.x. PMID 9694358. Steinle A, Groh V, Spies T (Oct 1998). " ... Tissue Antigens. 55 (2): 166-70. doi:10.1034/j.1399-0039.2000.550210.x. PMID 10746790. Cerwenka A, Bakker AB, McClanahan T, ... MHC class I polypeptide-related sequence B (MICB) is a protein that is encoded by the MICB gene located within MHC locus. MICB ...
Björklund B (1978). "Tissue polypeptide antigen (TPA): Biology, biochemistry, improved assay methodology, clinical significance ... Thymidine kinase has been determined in tissue samples after extraction of the tissue and a relation between the results and ... The TK1 levels in fetal tissues during development are higher than those of the corresponding tissues later. Certain non- ... The former was first found in fetal tissue, the second was found to be more abundant in adult tissue, and so initially they ...
January 2003). "Tissue polypeptide-specific antigen (TPS) determinations before and during intermittent maximal androgen ... Collette L, de Reijke TM, Schröder FH (August 2003). "Prostate specific antigen: a prognostic marker of survival in good ...
In normal tissue, MICA is expressed mainly intracellularly with just a small fraction appearing on the surface of some ... MICA plays the role of stress-induced self-antigen and serves as a ligand for the KLRK1/NKG2D killer activation receptor. ... MHC class I polypeptide-related sequence A (MICA) is a highly polymorphic cell surface glycoprotein encoded by the MICA gene ... Universal protein resource accession number Q29983 for "MICA - MHC class I polypeptide-related sequence A precursor - Homo ...
... tissue polypeptide antigen MeSH D23.050.290.249 - epstein-barr virus nuclear antigens MeSH D23.050.290.500 - ki-67 antigen MeSH ... tissue kallikreins MeSH D23.101.840.880 - tissue polypeptide antigen MeSH D23.119.300.300 - factor va MeSH D23.119.325.300 - ... antigens, cd15 MeSH D23.101.100.900.131 - antigens, cd31 MeSH D23.101.100.920 - antigens, ly MeSH D23.101.100.930 - antigens, ... forssman antigen MeSH D23.050.285.018 - antigens, cd24 MeSH D23.050.285.025 - antigens, cd30 MeSH D23.050.285.040 - antigens, ...
WHO Nomenclature Committee for factors of the HLA system". Tissue Antigens. 39 (4): 161-73. doi:10.1111/j.1399-0039.1992. ... low-molecular-mass polypeptides 2 and 7 are hyperexpressed by target cells in autoimmune thyroid disease but not in insulin- ... Tissue Antigens. 50 (2): 153-63. doi:10.1111/j.1399-0039.1997.tb02854.x. PMID 9271825. Madani N, Kabat D (Dec 1998). "An ... During the antigen processing for the major histocompatibility complex (MHC) class-I, the proteasome is the major degradation ...
... and they promote the repair of damaged tissue. A polypeptide called interleukin-5 interacts with eosinophils and causes them to ... These cells also have a limited ability to participate in phagocytosis, they are professional antigen-presenting cells, they ... Mast cells are a type of granulocyte that are present in tissues; they mediate host defense against pathogens (e.g., parasites ... MCs originate from a bone marrow progenitor and subsequently develop different phenotype characteristics locally in tissues. ...
Her career and research on tissue-resident memory T cells have been profiled by Pursuit. She has been interviewed by Science on ... In 2009, she was awarded her PhD, with a thesis entitled "Antigen processing and presentation for CD8+ and CD4+ T cell ... recognition: newly-synthesised polypeptides versus mature proteins". From 2009 to 2016, Mackay was a postdoctoral scientist in ... 27 October 2013). "The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin". Nature Immunology. 14 ( ...
The cleavage pattern of POMC, however, may vary between different tissues, yielding different sets of polypeptide hormones from ... Common names for the polyprotein include gag (group-specific antigen) in retroviruses and ORF1ab in Nidovirales. The latter ... Some proteins and most eukaryotic polypeptide hormones are synthesized as a large precursor polypeptide known as a polyprotein ... This polypeptide is subsequently cleaved into individual polypeptide chains. ...
"Entrez Gene: SNRP70 small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)". Spritz RA, Strunk K, Surowy CS, ... Antibodies towards snRNP70 are associated with mixed connective tissue disease. GRCh38: Ensembl release 89: ENSG00000104852 - ... ribonucleoprotein antigen". Protein Expression and Purification. 6 (6): 748-56. doi:10.1006/prep.1995.0005. PMID 8746626. Zhang ... Mohrenweiser HW (October 1990). "Human U1-70K ribonucleoprotein antigen gene: organization, nucleotide sequence, and mapping to ...
Tissue Antigens. 54 (5): 499-507. doi:10.1034/j.1399-0039.1999.540507.x. PMID 10599889. Epperson TK, Patel KD, McEver RP, ... 1998). "Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N-acetylgalactosaminyltransferase that complements ... Fuhlbrigge RC, Kieffer JD, Armerding D, Kupper TS (1997). "Cutaneous lymphocyte antigen is a specialized form of PSGL-1 ... is expressed on all white blood cells and plays an important role in the recruitment of white blood cells into inflamed tissue ...
Fixation of tissue is done for several reasons. One reason is to kill the tissue so that postmortem decay (autolysis and ... and extracts lipids to give superior results to formaldehyde in immunostaining of biogenic and polypeptide hormones However, it ... excellent preservation of protein antigens for immunohistochemistry and enzyme histochemistry, good RNA and DNA yields and ... In order for fixation to be successful, the fixative must diffuse throughout the entire tissue, so tissue size and density, as ...
sIgA has also been shown to potentiate the immune response in intestinal tissue by uptake of antigen together with the bound ... The pentamer also contains a polypeptide J-chain, which links two of the monomers and facilitates secretion at mucosal surfaces ... they are rarely highly mutated and have broad antigen reactivity thus providing an early response to a wide range of antigens ... IgG4 is the least abundant IgG subclass in the serum and is often generated following repeated exposure to the same antigen or ...
These cells bind antigens presented on MHC I complex of virus-infected or tumour cells and kill them. Nearly all nucleated ... Some leucocytes migrate into the tissues of the body to take up a permanent residence at that location rather than remaining in ... or display stress markers such as MHC class I polypeptide-related sequence A (MIC-A). Decreased expression of MHC class I and ... Often these cells have specific names depending upon which tissue they settle in, such as fixed macrophages in the liver, which ...
M2 macrophages resolve inflammation, help tissue healing, tolerate self-antigens and certain neoantigens (for example apoptotic ... nuclear factor of kappa light polypeptide gene enhancer (NF-κB), activator protein (AP-1) and STAT1. This leads to enhanced ... Some macrophages are known to be residing in the tissues and help in maintaining the tissue microenvironment. These came to be ... antigen presentation by MHC II system, and production of IL-10 and TGF-𝛽, leading to tissue regeneration and internalization of ...
AChE is found in many types of conducting tissue: nerve and muscle, central and peripheral tissues, motor and sensory fibers, ... Spring FA, Gardner B, Anstee DJ (1992). "Evidence that the antigens of the Yt blood group system are located on human ... Identification of residues involved in catalytic activity and in polypeptide folding". J. Biol. Chem. 267 (25): 17640-8. doi: ... Alternative exons dictate tissue-specific expression". J. Biol. Chem. 266 (34): 23083-90. doi:10.1016/S0021-9258(18)54466-5. ...
Milland J, Sandrin MS (December 2006). "ABO blood group and related antigens, natural antibodies and transplantation". Tissue ... In humans and most other mammals, an antibody unit consists of four polypeptide chains; two identical heavy chains and two ... Rh factor, also known as Rh D antigen, is an antigen found on red blood cells; individuals that are Rh-positive (Rh+) have this ... This occurs before the antigen can stimulate maternal B cells to "remember" Rh antigen by generating memory B cells. Therefore ...
In secretory lymphoid tissues (e.g., gut-associated lymphoid tissue, or GALT), the share of IgA2 production is larger than in ... Polysaccharide antigens tend to induce more IgA2 than protein antigens. Both IgA1 and IgA2 can be in membrane-bound form. (see ... One of these is the J chain (joining chain), which is a polypeptide of molecular mass 15kD, rich with cysteine and structurally ... Most lymphoid tissues have a predominance of IgA1-producing cells. In IgA2, the heavy and light chains are not linked with ...
When a large polypeptide is used to induce experimental allergic encephalomyelitis (EAE), a model of MS in animals, B cells are ... This process is thought to be similar to the onset of autoimmune disease in humans when a complex protein antigen is the ... Cross later found that DTI could also be used to effectively detect spinal cord tissue injury as well in ms and neuromyelitis ... To determine what the optimal response to rituximab therapy is, Cross looked at the tissue biomarkers of patients with multiple ...
Tissue Antigens. 75 (4): 291-455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336. derived from IMGT/HLA (HLA- ... B35 is one of the largest B serotype groups, it currently has 97 known nucleotide variants and 86 polypeptide isoforms. (For ...
"Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues". International Journal of ... The gene encodes a 180-amino acid polypeptide, expressed from 18 weeks during embryonic development until birth in human fetal ... Cancer/Testis Antigen 1B is a protein belonging to the family of Cancer Testis Antigens (CTA) that are expressed in a variety ... Cancer/testis antigen 1 also known as LAGE2 or LAGE2B is a protein that in humans is encoded by the CTAG1B gene. It is most ...
... the use of the antibody-antigen relationship in tissues). This technique primarily makes use of fluorophores to visualise the ... It is important to realize that this division is artificial and in reality the antibody molecule is four polypeptide chains: ... Likewise, an antigen can also be conjugated to the antibody with a fluorescent probe in a technique called fluorescent antigen ... Staining procedures can apply to both fixed antigen in the cytoplasm or to cell surface antigens on living cells, called " ...
... polypeptide 1 CYP11B2: cytochrome P450, family 11, subfamily B, polypeptide 2 DCSTAMP: dendrocyte expressed seven transmembrane ... sperm-associated antigen 11B STAU2: staufen double-stranded RNA binding protein 2 SYBU: Syntabulin TG: thyroglobulin THAP1: ... tissue plasminogen activator TRMT12: tRNA methyltransferase 12 homolog TRPS1: trichorhinophalangeal syndrome I TSPYL5 (gene): ... light polypeptide 68kDa ODF1: outer dense fiber protein 1 OTUD6B: OTU domain containing 6B PDP1: pyruvate dehydrogenase ...
... desloughing and debriding of necrotic and fibrotic tissue Tissue engineering scaffolds. When used as scaffolds, hydrogels may ... Biosensors: Hydrogels that are responsive to specific molecules, such as glucose or antigens, can be used as biosensors, as ... Materials include agarose, methylcellulose, hyaluronan, elastin-like polypeptides, and other naturally derived polymers. ... This technique has seen considerable use in cell and tissue engineering applications due to the ability to inject or mold a ...
V(D)J recombination is necessary for recognition of a diverse range of antigens from bacteria, viruses, and parasites. It is ... They have been extensively used as hosts for normal and malignant tissue transplants. In addition, they are useful for testing ... catalytic polypeptide"). Because V(D)J recombination does not occur, the humoral and cellular immune systems fail to mature. As ...
Genetic mapping of the loci controlling the class I and class II antigens of the mouse showed them to be part of a cluster, ... The name referred to the fact that the genes were part of a set that controlled tissue compatibility and in this set one ... locus influencing the level of antibody production against the synthetic polypeptide (T,G)-L-A into the Mhc. Klein and his ... The class I genes were discovered in 1936 (the year Jan Klein was born) as coding for blood group (red blood cell) antigens, ...
For many years Lisowska worked on the M and N antigens. She identified that these antigens were carried by the glycosylated ... She became head of Laboratory of Tissue Immunochemistry (later Laboratory of Glycoconjugate Immunochemistry) at the Hirszfeld ... but later it emerged that there were differences in amino acid sequence of polypeptide chain. Lisowska was the first to show ... which is the cause of NOR polyagglutination and a member of the human P1PK antigen system. and showed that the NOR antigen is ...
17: 568-572, 1999 Chang, K., Pai, L.H., Batra, J.K., Pastan, I., and Willingham, M.C.: Characterization of the antigen (CAK1) ... Review-lead article). Science 169: 339-344, 1970 Pastan, I., Roth, J., and Macchia, V.: Binding of hormone to tissue: The first ... He then proceeded to study hormone interactions with living cells using fluorescence photo-bleaching to visualize polypeptide ... 50: 373-381, 1992 Chang, K. and Pastan, I.: Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, ...
This antigen is also known as the Rs(a) antigen. The Ahonen (Ana) antigen was first reported in 1972. The antigen is found on ... Glycophorin C (GPC) is a single polypeptide chain of 128 amino acids and is encoded by a gene on the long arm of chromosome 2 ( ... Two isoforms are known and the gene is expressed in a wide variety of tissues including kidney, thymus, stomach, breast, adult ... The antigen was discovered in 1960 when three women who lacked the antigen made anti-Gea in response to pregnancy. The antigen ...
Neuropilin (A5 antigen), a calcium-independent cell adhesion molecule that functions during the formation of certain neuronal ... The porcine spermadhesin polypeptides are coded by five closely linked genes. Bovine spermadhesin relies on a significantly ... tissue repair, axon guidance and angiogenesis, cell signalling, fertilisation, haemostasis, inflammation, neurotransmission, ... Spermadhesins are 110-133 amino acid polypeptides. The binding activity of spermadhesins, e.g. heparin and carbohydrate binding ...
Since the gold nanoparticles are taken up by the tumors more than the nearby healthy tissue, the dose is selectively enhanced. ... Colloidal gold and various derivatives have long been among the most widely used labels for antigens in biological electron ... colocalization of simian virus 40 Vp1 polypeptide and actin in TC7 cells". Proceedings of the National Academy of Sciences of ... Since near-infrared light transmits readily through human skin and tissue, these nanorods can be used as ablation components ...