The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially ... At least two isoforms of mammalian arginase exists (types I and II, this enzyme) which differ in their tissue distribution, ...
The surfactant is responsible for lung elasticity, that is for lung tissue's ability to contract and expand. For example, ... CTL2s occur especially in the mitochondria in the tongue, kidneys, muscles and heart. They are associated with the ... Choline is in high demand during pregnancy as a substrate for building cellular membranes (rapid fetal and mother tissue ... CTL1s have moderate affinity for choline and transport it in almost all tissues, including the intestines, liver, kidneys, ...
Doxorubicin has been shown to be selectively toxic to cardiac tissue, although some toxicity has been seen in other tissues as ... is an uncoupling agent in that it inhibits proper functioning of complex I of the electron transport chain in mitochondria. It ... A very common mechanism is covalent binding of either the drug or its metabolites to specific enzymes or receptor in tissue- ...
... and other tissues enriched in mitochondria. Nonetheless, FASTKD2 has been observed to mediate apoptosis independent of import ... Though ubiquitously expressed in all tissues, FASTKD2 appears more abundantly in skeletal muscle, heart muscle, ... and then this term was replaced by apoptosis to emphasize its role opposite mitosis in tissue kinetics. In later stages of ... The mitochondrial targeting domain directs FASTKD2 to be imported into the mitochondria. Though the functions of the C-terminal ...
... connective tissue, kidney, lungs, parathyroid, pharynx, placenta, testis and trachea. In mouse, the gene expression of C6orf165 ... Less likely possibilities are in the mitochondria (21%) or in the nucleus (17%) or in vacuoles (4%). From the EST file of ...
P450scc is also present at much lower levels in several other tissue types, including the brain. In the adrenal cortex, the ... Hanukoglu I, Rapoport R (1995). "Routes and regulation of NADPH production in steroidogenic mitochondria". Endocrine Research. ... This is the first reaction in the process of steroidogenesis in all mammalian tissues that specialize in the production of ... level of P450scc in the mitochondria) is now more important. Corticotropin (ACTH) is a hormone that is released from the ...
In the cell, action in the cytosol, the mitochondria, and the glycosome are all completing the function of energy metabolism. ... Because the lyoglycosomes are not bound to tissue, it is possible to extract these glycosomes with water that is boiling. ... Desmoglycosomes are not extractable from boiling water as they are bound to tissue through their connection to protein. The ... These structures relate to the other organelles mentioned such as the myofibrils, mitochondria, and endoplasmic reticulum. This ...
A total recovery of 98% was found 72 hours after administration in several tissues and the percentages of reactivity found in ... Recent studies show that the mitochondria respiratory system is another target of citrinin. Citrinin can interfere with the ... Table 1: Distribution of citrinin through tissues Most of the radioactively labeled citrinin (77%) was excreted via urine. ... which shows that there is an accumulation of the citrinin in kidney tissue. It is also shown that citrinin is transported into ...
In the arteries of the brain, high levels of calcium in mitochondria elevates activity of nuclear factor kappa B NF-κB and ... Cell and Tissue Research. 357 (2): 463-76. doi:10.1007/s00441-014-1936-3. PMID 24996399. S2CID 15914718. "Entrez Gene: voltage- ... dependent, L type, alpha 1C subunit". Narayanan D, Xi Q, Pfeffer LM, Jaggar JH (Sep 2010). "Mitochondria control functional ...
The adrenal glands have one of the greatest blood supply rates per gram of tissue of any organ: up to 60 small arteries may ... Cells contain numerous lipid droplets, abundant mitochondria and a complex smooth endoplasmic reticulum. The innermost cortical ... Adrenal cortex tissue is derived from the intermediate mesoderm. It first appears 33 days after fertilisation, shows steroid ... Cells in this layer form oval groups, separated by thin strands of connective tissue from the fibrous capsule of the gland and ...
Hanson's group was the first to utilize GFP technology to label plastids and mitochondria in plants. As a result, Rainer Köhler ... Hanson named these structures "stromules" and demonstrated that proteins flow through them and examined their tissue-specific ... Hanson has also made many contributions to the understanding of C-to-U RNA editing in chloroplasts and plant mitochondria. ... Lu, B.; Hanson, M. R. (1994-12-01). "A single homogeneous form of ATP6 protein accumulates in petunia mitochondria despite the ...
The filtration of serum proteins and fluid from the vessel causes the tissue to become oedematous. The tissue pressure ... and degeneration of mitochondria. It is unknown by which process (apoptosis or necrosis) the odontoblasts die. Lymphocytes, ... It is the result of various connective tissue disease progressions which occur in stages; normal healthy tissue becomes ... the increased pressure cannot be displaced to other tissues, resulting in pressure on the nerve of said tooth and tissues ...
This is because fatty acids can only be metabolized in the mitochondria. Red blood cells do not contain mitochondria and are ... In all other tissues, the fatty acids that enter the metabolizing cells are combined with coenzyme A to form acyl-CoA chains. ... All cells with mitochondria can take ketone bodies up from the blood and reconvert them into acetyl-CoA, which can then be used ... Fats stored in adipose tissue are released from the fat cells into the blood as free fatty acids and glycerol when insulin ...
Degeneration of nerve tissue in the spinal cord causes the ataxia; particularly affected are the sensory neurons essential for ... It also regulates iron transfer in the mitochondria by providing a proper amount of reactive oxygen species (ROS) to maintain ... Degeneration of nerve tissue in the spinal cord causes ataxia. The sensory neurons essential for directing muscle movement of ... Without frataxin, the energy in the mitochondria falls, and excess iron creates extra ROS, leading to further cell damage. Low ...
Basophilic chromidia and mitochondria in normal and in tumor tissue. The Journal of Histochemistry and Cytochemistry, 3(3), 212 ...
... and other tissues enriched in mitochondria. FASTKD1 has been validated as an RNA-binding protein. FASTKD1 is an important ... As a member of the FASTKD family, FASTKD1 localizes to the mitochondria to modulate their energy balance, especially under ... Kerr JF, Wyllie AH, Currie AR (Aug 1972). "Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue ... Though ubiquitously expressed in all tissues, FASTKD1 appears more abundantly in skeletal muscle, heart muscle, ...
The brown tissue revealed elevated levels of mitochondria respiration and another respiration not coupled to ATP synthesis, ... Mitochondria respiration is coupled to ATP synthesis (ADP phosphorylation), but is regulated by UCPs. UCPs belong to the ... These brown adipose tissues are essential to maintaining the body temperature of small rodents, and studies with (UCP1)- ... Mitochondria are a major site of calcium storage in neurons, and the storage capacity increases with potential across ...
... and other tissues enriched in mitochondria. FASTKD3 has been proposed to regulate energy production by serving as a scaffold ... As a member of the FASTKD family, FASTKD3 localizes to the mitochondria to modulate their energy balance, especially under ... Though ubiquitously expressed in all tissues, FASTKD3 appears more abundantly in skeletal muscle, heart muscle, ... The mitochondrial targeting domain directs FASTKD3 to be imported into the mitochondria. Though the functions of the C-terminal ...
Ants have high diets in animal tissue which is correlated to a faster release of nutrients and they trim encroaching vegetation ... The cells lining the nest show layers enriched with endoplasmic reticulum, dictyosomes, mitochondria and higher levels of ... Rickson, Fred R. (January 1979). "ABSORPTION OF ANIMAL TISSUE BREAKDOWN PRODUCTS INTO A PLANT STEM-THE FEEDING OF A PLANT BY ... and vascular tissues of the stem, showing translocation of materials by the plant. Ultimately, there was a positive and direct ...
This conversion is the rate-limiting step of steroid synthesis, which occurs inside the mitochondrion of the respective tissue ... Rossier MF (August 2006). "T channels and steroid biosynthesis: in search of a link with mitochondria". Cell Calcium. 40 (2): ... in biological tissue or fluid). The amount isolated depends on the analytical method, but is generally less than one microgram ... and all human tissues which produce steroids must first convert cholesterol to pregnenolone. ...
... has high levels of expression in the testis and lower levels in the brain and connective tissues. Through the ... The protein is predicted to be localized in the Mitochondria, with little indication of extracellular activity. Expanded ...
... having numerous fast voltage-gated sodium channels and mitochondria, and fewer myofibrils, than the surrounding muscle tissue ... This causes the muscle tissue of the ventricles to contract. This generates force to eject blood out of the heart, either to ... They are larger than cardiomyocytes with fewer myofibrils and many mitochondria. They conduct cardiac action potentials more ... The Purkinje fibers (English: /pɜːrˈkɪndʒi/ pur-KIN-jee; Czech: [ˈpurkɪɲɛ] ; Purkinje tissue or subendocardial branches) are ...
... despite physiologically normal delivery of oxygen to such cells and tissues. Histotoxic hypoxia results from tissue poisoning, ... This causes the mitochondria to produce ATP again and stop histotoxic hypoxia. Histotoxic hypoxia can be a consequence of ... There is a profound drop in tissue oxygen consumption since the reaction of oxygen with cytochrome oxidase is blocked by the ... This completely stops oxidative phosphorylation and prevents the mitochondria from producing ATP. There are other chemicals ...
The AK2 protein is found in the intermembrane space of the mitochondrion. Adenylate kinases are involved in regulating the ... 1998). "cDNA cloning and tissue-specific expression of the gene encoding human adenylate kinase isozyme 2". Biochim. Biophys. ... 1982). "Adenosine triphosphate-adenosine-5'-monophosphate phosphotransferase from normal human liver mitochondria. Isolation, ... differential expression of adenylate kinase 1 and 2 in human muscle tissues". J. Biochem. 123 (1): 47-54. doi:10.1093/ ...
"Mitochondria (and other cytoplamic structures) in tissue cultures" (PDF). American Journal of Anatomy. 17 (3): 339-401. doi: ... Because of the danger of having damaged mitochondria in the cell, the timely elimination of damaged and aged mitochondria is ... It is localized to the mitochondria. Once mitophagy is initiated, Atg32 binds to Atg11 and the Atg32-associated mitochondria ... Because of their role in metabolism, mitochondria are very susceptible to ROS damage. Damaged mitochondria cause a depletion in ...
During flight and hovering, oxygen consumption per gram of muscle tissue in a hummingbird is about 10 times higher than that ... this extraordinary capacity for oxygen consumption by an exceptional density and proximity of capillaries and mitochondria in ...
In this way, the ECM of a particular tissue may help coordinate the behavior of all the cells within that tissue. Direct ... In the mitochondrion, the matrix contains soluble enzymes that catalyze the oxidation of pyruvate and other small organic ... It is found in various connective tissues. It serves as a jelly-like structure instead of cytoplasm in connective tissue. The ... Cartilage is another form of connective tissue found in the body, providing a smooth surface for joints and a mechanism for ...
The activity of PRDM16 in white adipose tissue leads to the production of brown fat-like adipocytes within white adipose tissue ... Brown adipocytes consist of densely packed mitochondria that contain uncoupling protein 1 (UCP-1). UCP-1 plays a key role in ... Brown adipose tissue (BAT) oxidizes chemical energy to produce heat. This heat energy can act as a defense against hypothermia ... White adipose tissue (WAT) primarily stores excess energy in the form of triglycerides. Recent research has shown that PRDM16 ...
... early-stage research of in vivo pro-longevity nanotechnology Tissue engineering: of tissues and organs (see also: ... such as MOTS-c released by mitochondria Mitochondria modulation: early-stage research indicates mitochondrial interventions ... A review suggests mitochondria have a hormetic response to ROS, whereby low oxidative damage can be beneficial. As of 2021, ... SENS proposes that rejuvenation may be obtained by removing aging damage via the use of stem cells and tissue engineering, ...
SK2 is located mainly in the mitochondria, nucleus and the endoplasmic reticulum whereas SK1 is mainly located in cytoplasm and ... These two enzymes have different tissue distribution. SK1 is highly expressed in spleen, lung and leukocytes, while SK2 is ... S1P has protected ovarian tissue xenografts in SCID mouse models from radiation induced atresia. In animal models these ... It is less abundant in tissue fluids. This is referred to as the S1P gradient, which seems to have biological significance in ...