The ST staple is a common four- or five-amino acid residue motif in proteins and polypeptides with serine or threonine as the C ... It is characterized by a single hydrogen bond between the hydroxyl group of the serine or threonine (at residue i + 3 or i + 4 ... Ballesteros, JA; Deupi X (2000). "Serine and threonine residues bend alpha-helices in the chi(1) 5 g(-) conformation". ... Gray, TM; Matthews BW (1984). "Intrahelical hydrogen bonding of serine, threonine and cysteine residues within α-helices. ...

This can occur at serine, threonine, or tyrosine residues present in euchromatin. Since the phosphate groups added to the ...

This includes serine and threonine phosphorylation, lysine acetylation, lysine methylation and ubiquitination. These PTMs serve ...

Serine/Threonine kinases are also known to reduce the activity of insulin. The structure of the insulin-insulin receptor ...

"The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity". Biochem. J. 451 (1): 45-53. doi:10.1042/ ...

This enzyme participates in glycine, serine and threonine metabolism and glycerophospholipid metabolism. Larson TJ, Dowhan W ( ...

Serine/threonine-protein kinase 12, AIK2, AIM1, ARK2, STK12) Aurora-C (Serine/threonine-protein kinase 13, AIE2, AIK3, STK13) ... Graham M. T. et al., Crystal Structure of Aurora-2, an Oncogenic Serine/Threonine Kinase J. Biol. Chem., (2002) 277: pp.42419- ... 22 Aurora-A (Serine/threonine-protein kinase 6, AIK, ARK1, AURA, BTAK, STK15, STK6) Aurora-B ( ...

"Organization of threonine biosynthesis genes from the obligate methylotroph Methylobacillus flagellatus" Microbiology. 1999. ...

Giet R, Prigent C. Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases. Journal of Cell ... Aurora kinases are serine/threonine kinases that are essential for cell proliferation. They are phosphotransferase enzymes that ...

Spontaneous cleavage of proteins may also involve catalysis by zinc on serine and threonine. Strong mineral acids can readily ... Cysteine protease Serine protease Threonine protease Aspartic protease Glutamic protease Metalloprotease Asparagine peptide ... and threonine (the so-called PEST proteins) have short half-life. Other factors suspected to affect degradation rate include ... "Spontaneous cleavage of proteins at serine and threonine is facilitated by zinc". Aging Cell. 15 (2): 237-244. doi:10.1111/acel ...

There are 32 predicted serine phosphorylation sites, 5 threonine, and 3 tyrosine. CCDC82 is known to interact with two proteins ...

It has much less activity (IC50s > 1 μM) against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. In vivo ...

"TAOK3 - Serine/threonine-protein kinase TAO3 - Homo sapiens (Human) - TAOK3 gene & protein". www.uniprot.org. Retrieved 2022-01 ... Since MAPKKK are activated through the addition of a phosphates group on a serine/threonine residue, they are deactivated by a ... Mitogen Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein ...

These threonine-insensitive forms of HSD are used in genetically engineered plants to increase both threonine and methionine ... However, some threonine-resistant HSD forms exist that require concentrations of threonine much greater than physiologically ... mainly threonine. Threonine acts as a competitive inhibitor for both HSD and aspartate kinase. In AK-HSD expressing organisms, ... As lysine, threonine, methionine, and isoleucine are made in this pathway, they are considered essential amino acids for ...

This enzyme participates in glycine, serine and threonine metabolism and glycerophospholipid metabolism. Hirata F, Viveros OH, ...

Waskiewicz AJ, Flynn A, Proud CG, Cooper JA (April 1997). "Mitogen-activated protein kinases activate the serine/threonine ... "Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a ...

2004). "Activin isoforms signal through type I receptor serine/threonine kinase ALK7". Mol. Cell. Endocrinol. 220 (1-2): 59-65 ... expression studies and chromosome mapping of human type I serine/threonine kinase receptor ALK7 (ACVR1C)". Cytogenet. Cell ...

O-linked glycosylation is the attachment of a sugar molecule to the oxygen atom of serine (Ser) or threonine (Thr) residues in ... One of the first and only examples of O-glycosylation on tyrosine, rather than on serine or threonine residues, is the addition ... Several different sugars can be added to the serine or threonine, and they affect the protein in different ways by changing ... Addition of fucose sugars to serine and threonine residues is an unusual form of O-glycosylation that occurs in the endoplasmic ...

They are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, and histidine. There has been ...

"Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action". Neuropsychopharmacology. 31 (3): 555-62. doi: ...

Serine/threonine-protein kinase PLK4 also known as polo-like kinase 4 is an enzyme that in humans is encoded by the PLK4 gene. ... PLK4 encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles-complex ... Overview of all the structural information available in the PDB for UniProt: O00444 (Human Serine/threonine-protein kinase PLK4 ... Overview of all the structural information available in the PDB for UniProt: Q64702 (Mouse Serine/threonine-protein kinase PLK4 ...

This enzyme participates in glycine, serine and threonine metabolism, and glycerophospholipid metabolism. It has two cofactors ...

Asparagine and aspartic acid are both larger than threonine, and both asparagine and aspartic acid like to be in a turn while ... Asparagine and aspartic acid are both hydrophilic, while threonine has intermediate hydrophilicity. ... threonine prefers a beta strand. Aspartic acid and asparagine carry a formal charge. This charge however is negative for ...

2001). "A serine/threonine kinase p90rsk1 phosphorylates the anti-proliferative protein Tob". Genes Cells. 6 (2): 131-8. doi: ...

... the threonine permease (TC# 2.A.42.2.2), of E. coli. Thus[clarification needed], FhuA (TC# 1.B.14.1.4) transports phage T5 DNA ...

"Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin". Nature Communications. 13 (1): 4202. Bibcode:2022NatCo.. ...

Multiple nutrients fuel one-carbon metabolism, including glucose, serine, glycine, and threonine. High levels of the methyl ...

The results revealed that a diet containing 18.69% protein and 0.73% threonine may lead to producing optimal weight gain, ... Ahmadi, H.; Golian, A. (2010-11-01). "The integration of broiler chicken threonine responses data into neural network models". ... whereas the optimal feed efficiency may be achieved with a diet containing 18.71% protein and 0.75% threonine. There are a few ... feed efficiency from a compiled data set suggested that the dietary protein concentration was more important than the threonine ...

Changeux J.-P. (1961). The feedback control mechanism of biosynthetic L-threonine deaminase by L-isoleucine. Cold Spring Harbor ...

A similar attenuation mechanism regulates the synthesis of histidine, phenylalanine and threonine. The arrangement of the trp ...