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*  Nav1.7
The Nav1.7 channel produces a rapidly activating and inactivating current which is sensitive to the level of tetrodotoxin. ... "Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from ... can be differentiated by their voltage dependence and by sensitivity to the voltage-gated sodium-channel blocker tetrodotoxin. ...
*  SCN7A
Its sequence identity is 48, and it is the only sodium channel known to be completely un-blockable by TTX (tetrodotoxin). ...
*  Tetrodotoxin
... has been used clinically to relieve the headache associated with heroin withdrawal. In the U.S., tetrodotoxin ... "Tetrodotoxin". Guide to Pharmacology. IUPHAR/BPS. Kao, C.Y. (1966). "Tetrodotoxin, saxitoxin and their significance in the ... Tetrodotoxin at the US National Library of Medicine Medical Subject Headings (MeSH) Tetrodotoxin: essential data (1999) ... This is the first reported case in which tetrodotoxin has been found to occur in a venom. "Tetrodotoxin". PubChem. National ...
*  Vibrionaceae
Members of this family also synthesize tetrodotoxin (TTX), an ancient marine alkaloid and powerful neurotoxin (Na+ pump ... Johnson J (2002-01-05). "Tetrodotoxin". Molecule of the Month. Retrieved 2008-10-07. Edwards N (1998-08-18). "Saxitoxin". ...
*  Neosaxitoxin
Toxins such as neosaxitoxin and tetrodotoxin have less affinity for most cardiac Nav channels than for most Nav channels in ... How CK, Chern CH, Huang YC, Wang LM, Lee CH (January 2003). "Tetrodotoxin poisoning". The American Journal of Emergency ... Vornanen M, Hassinen M, Haverinen J (2011). "Tetrodotoxin sensitivity of the vertebrate cardiac Na+ current". Marine Drugs. 9 ( ... Schwartz DM, Duncan KG, Fields HL, Jones MR (October 1998). "Tetrodotoxin: anesthetic activity in the de-epithelialized cornea ...
*  Fugu
Researchers have surmised that fugu's tetrodotoxin comes from eating other animals infested with tetrodotoxin-laden bacteria, ... Tetrodotoxin (TTX) is a natural product that has, as of 2015, been isolated from puffer fish, but also from octopuses, from ... Fugu can be lethally poisonous due to its tetrodotoxin; therefore, it must be carefully prepared to remove toxic parts and to ... Fugu contains lethal amounts of the poison tetrodotoxin in its inner organs, especially the liver, the ovaries, eyes, and skin ...
*  Neurotoxin
Tetrodotoxin (TTX) is a poison produced by organisms belonging to the Tetradontidae order, which includes the puffer fish, ... How, C (2003). "Tetrodotoxin Poisoning". The American Journal of Emergency Medicine. 21 (1): 51-54. doi:10.1053/ajem.2003.50008 ... Chowdhury, F. R.; Ahasan, H A M. Nazmul; Rashid, A K M. Mamunur; Mamun, A. Al; Khaliduzzaman, S. M. (2007). "Tetrodotoxin ... Kiernan, Matthew C.; Isbister, Geoffrey K.; Cindy; Lin, S.-Y.; Burke, David; Bostock, Hugh (2005). "Acute Tetrodotoxin-induced ...
*  Wade Davis (anthropologist)
Benedek, C. and L. Rivier (1989), "Evidence for the presence of tetrodotoxin in a powder used in Haiti for zombification", ... They reported that only "insignificant traces of tetrodotoxin [were found] in the samples of 'zombie powder' which were ... In 1983, Davis first advanced his hypothesis that tetrodotoxin (TTX) poisoning could explain the existence of Haitian zombies. ... Anderson, W.H. (1988). "Tetrodotoxin and the Zombie Phenomenon". Journal of Ethnopharmacology. 23: 121-126. Kao, C.Y.; Yasumoto ...
*  Tetrahedral carbonyl addition compound
Woodward, R. B.; Gougoutas, J. Z. (1964). "The Structure of Tetrodotoxin". J. Am. Chem. Soc. 86 (22): 5030. doi:10.1021/ ... e.g.tetrodotoxin) compounds with a strong electron-withdrawing group attached to the acyl carbon (e.g.N,N- ...
*  Nav1.9
Though most sodium channels are blocked by tetrodotoxin, Nav1.9 is tetrodotoxin-resistant due to the presence of serine on an ... Qiu F, Jiang Y, Zhang H, Liu Y, Mi W (March 2012). "Increased expression of tetrodotoxin-resistant sodium channels Nav1.8 and ... Dib-Hajj SD, Tyrrell L, Cummins TR, Black JA, Wood PM, Waxman SG (November 1999). "Two tetrodotoxin-resistant sodium channels ... Baker MD, Chandra SY, Ding Y, Waxman SG, Wood JN (April 2003). "GTP-induced tetrodotoxin-resistant Na+ current regulates ...
*  Takifugu
The fish contains lethal amounts of the poison tetrodotoxin in the internal organs, especially the liver and the ovaries, but ... Pufferfish that are born and grown in captivity do not produce tetrodotoxin until they receive some of the poison-producing ... The toxin is called tetrodotoxin, or more precisely anhydrotetrodotoxin 4-epitetrodotoxin and is about 1200 times deadlier than ... 1 July 1987). "Marine Bacteria Which Produce Tetrodotoxin". AEM. ASM. 53 (7): 1714-5. PMC 203940 . PMID 3310884. Matsuura, ...
*  Black-blotched porcupinefish
Tetrodotoxin is a powerful neurotoxin. This defensive system constitutes an additional device to dissuade the potential ... The porcupinefish concentrates a poison, called tetrodotoxin, in certain parts of its body such as the liver, skin, gonads and ...
*  Blue-ringed octopus
Tetrodotoxin is 1,200 times more toxic than cyanide. Tetrodotoxin blocks sodium channels, causing motor paralysis, and ... Tetrodotoxin causes severe and often total body paralysis. Tetrodotoxin envenomation can result in victims being fully aware of ... The tetrodotoxin is produced by bacteria in the salivary glands of the octopus. A person must be in contact with the octopus to ... "Tetrodotoxin and the Life Tree". Retrieved 2011-04-22. Roy Caldwell. "What makes blue-rings so deadly?". Retrieved 2007-03-19. ...
*  Pseudoalteromonas tetraodonis
It secretes the neurotoxin, tetrodotoxin. It was originally described in 1990 as Alteromonas tetraodonia but was reclassified ...
*  Octopus
It contains tetrodotoxin, which causes paralysis by blocking the transmission of nerve impulses to the muscles. This causes ... "What makes blue-rings so deadly? Blue-ringed octopus have tetrodotoxin". The Cephalopod Page. Retrieved 12 April 2017. Wells ( ...
*  Channel blocker
Tetrodotoxin (TTX), a toxin found in pufferfish, completely blocks sodium ion transportation by blocking the selectivity filter ... Moore JW, Blaustein MP, Anderson NC, Narahashi T (May 1967). "Basis of tetrodotoxin's selectivity in blockage of squid axons". ... Evans MH (September 1969). "Mechanism of saxitoxin and tetrodotoxin poisoning". British Medical Bulletin. 25 (3): 263-7. doi: ...
*  Atelopus chiriquiensis
... they produce tetrodotoxin, a potent neurotoxin. This once locally abundant species has not been seen in Costa Rica after 1996 ...
*  Chuck Versus the Predator
Before they can question Vincent, he ingests tetrodotoxin. Casey dumps Vincent's body in Castle. Beckman stops Chuck from ... having been trained to survive tetrodotoxin's near-death state. Meanwhile, Sarah and Casey realize that Chuck has left his ...
*  Purkinje cell
"Tetrodotoxin-resistant dendritic spikes in avian Purkinje cells". Proc. Natl. Acad. Sci. U.S.A. 73 (7): 2520-3. doi:10.1073/ ...
*  Red Sea species hazardous to humans
Boxfish also accumulate tetrodotoxin and are poisonous to eat. This is the Yellow boxfish, Ostracion cubicus which is ... Pufferfish, including this masked puffer accumulate a neurotoxin called tetrodotoxin in their skin and internal organs. This ...
*  Alteromonas
"Taxonomy of Four Marine Bacterial Strains That Produce Tetrodotoxin". International Journal of Systematic Bacteriology. 40 (4 ...
*  Shewanella algae
They produce the toxin tetrodotoxin and can infected humans. S. algae is a facultative anaerobe with the ability to reduce iron ...
*  Action potential
Tetrodotoxin from the pufferfish and saxitoxin from the Gonyaulax (the dinoflagellate genus responsible for "red tides") block ... Nakamura Y, Nakajima S, Grundfest H (1965). "The effect of tetrodotoxin on electrogenic components of squid giant axons". J. ... Ritchie JM, Rogart RB (1977). "The binding of saxitoxin and tetrodotoxin to excitable tissue". Rev. Physiol. Biochem. Pharmacol ...
*  CgNa toxin
CgNa has an effect on tetrodotoxin-sensitive sodium channels. More specifically, in mammals it affects isoforms rNav1.3/β1, ... It causes an increased action potential duration by slowing down the inactivation of tetrodotoxin-sensitive sodium channels. " ... CgNa slows the inactivation of tetrodotoxin-sensitive sodium currents and thereby increases the action potential duration. It ...
*  Starfish
Some starfish such as Astropecten polyacanthus also include powerful toxins such as tetrodotoxin among their chemical armoury, ... Lin SJ, Hwang DF; Hwang (April 2001). "Possible source of tetrodotoxin in the starfish Astropecten scoparius". Toxicon. 39 (4 ... and others contain tetrodotoxins which are poisonous. Some species that prey on bivalve molluscs can transmit paralytic ...