Tacrolimus
"Tacrolimus Injection". MedlinePlus. "Tacrolimus Topical". MedlinePlus. Tacrolimus at the U.S. National Library of Medicine ... "Prograf- tacrolimus capsule, gelatin coated Prograf- tacrolimus injection, solution Prograf- tacrolimus granule, for suspension ... Generic versions of tacrolimus were approved in the US in 2017. Tacrolimus was approved for medical use in the European Union ... "Tacrolimus for Dogs and Cats". Baldo A, Cafiero M, Di Caterino P, Di Costanzo L (January 2009). "Tacrolimus ointment in the ...
Calcineurin
"Tacrolimus". New Zealand Formulary v81. 1 March 2019. Fuentes JJ, Genescà L, Kingsbury TJ, Cunningham KW, Pérez-Riba M, ... Thus tacrolimus contributes to the frequent development of new diabetes following renal transplantation. Calcineurin/NFAT ... "Pharmacology and side effects of cyclosporine and tacrolimus". UpToDate. 2014-04-10. Bannai H, Lévi S, Schweizer C, Inoue T, ... Calcineurin inhibitors such as tacrolimus are used to suppress the immune system in organ allotransplant recipients to prevent ...
Pyoderma gangrenosum
Topical application of clobetasol, mupirocin, and gentamicin alternated with tacrolimus can be effective. Pyoderma gangrenosum ... tacrolimus; thalidomide; infliximab; or plasmapheresis. Superficial granulomatous pyoderma Brown recluse spider bite Jackson JM ...
Khellin
Plettenberg, Heidi; Assmann, Till; Ruzicka, Thomas (2003). "Childhood vitiligo and tacrolimus". Arch. Dermatol. 139 (5): 651- ...
Streptomyces tacrolimicus
... produces tacrolimus. List of Streptomyces species LPSN bacterio.net Straininfo of Streptomyces ... nov., a low producer of the immunosuppressant tacrolimus (FK506)". International Journal of Systematic and Evolutionary ... nov., a low producer of the immunosuppressant tacrolimus (FK506)". International Journal of Systematic and Evolutionary ...
Ascomycin
Tacrolimus, Pimecrolimus Andexer, Jennifer; Kendrew, Steven; Nur-e-Alam, Mohammad; Wilkinson, Barrie (March 7, 2011). " ... Ascomycin, also called Immunomycin, FR-900520, FK520, is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant ...
Atopic dermatitis
Both tacrolimus and pimecrolimus are effective and safe to use in AD. Crisaborole, an inhibitor of PDE-4, is also effective and ... Cury Martins J, Martins C, Aoki V, Gois AF, Ishii HA, da Silva EM (July 2015). "Topical tacrolimus for atopic dermatitis". The ... Creams based on calcineurin inhibitors (tacrolimus or pimecrolimus) may also be used to control flares if other measures are ... If topical corticosteroids and moisturisers fail, short-term treatment with topical calcineurin inhibitors such as tacrolimus ...
Pimecrolimus
... short-term treatment with topical calcineurin inhibitors such as tacrolimus or pimecrolimus may be tried. Both tacrolimus and ... Cury Martins J, Martins C, Aoki V, Gois AF, Ishii HA, da Silva EM (July 2015). "Topical tacrolimus for atopic dermatitis". The ... Pimecrolimus has a similar mode of action to that of tacrolimus but is more selective, with no effect on dendritic (Langerhans ... Tacrolimus and pimecrolimus are both calcineurin inhibitors and function as immunosuppressants. If topical corticosteroids and ...
Cradle cap
"Tacrolimus Topical: MedlinePlus Drug Information". medlineplus.gov. "Pimecrolimus Topical: MedlinePlus Drug Information". ... The immunomodulators tacrolimus/Protopic and pimecrolimus/Elidel have not been approved for children under two years. ...
Graft-versus-host disease
Methotrexate, cyclosporin and tacrolimus are common drugs used for GvHD prophylaxis. Further research is necessary to evaluate ... Cyclosporine binds to the cytosolic protein Peptidyl-prolyl cis-trans isomerase A (known as cyclophilin), while tacrolimus ... November 2016). "A prospective randomized trial comparing cyclosporine/methotrexate and tacrolimus/sirolimus as graft-versus- ... Cyclosporine and tacrolimus are calcineurin inhibitors. The substances are structurally different but have the same mechanism ...
Inhaled ciclosporin
"Systemic ciclosporin and tacrolimus in dermatology. Dermatol Ther. 2007 Jul-Aug;20(4):239-50. Kitahara K, Kawai S. " ... "Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis. Curr Opin Rheumatol. 2007 May;19(3):238-45. Review. ...
Streptomyces tsukubensis
... produces the immunosuppressant tacrolimus. List of Streptomyces species LPSN bacterio.net Straininfo ... the producer of the clinically important immunosuppressant tacrolimus (FK506)". Journal of Bacteriology. 194 (14): 3756-7. doi: ...
Kimura's disease
A patient with refractory Kimura's disease after surgery and treatment with prednisone was treated with tacrolimus. Tacrolimus ... Tacrolimus may be an effective treatment for patients with Kimura's disease, but more research is needed to determine its long- ... Da-Long S, Wei R, Bing G, Yun-Yan Z, Xiang-Zhen L, Xin L (February 2014). "Tacrolimus on Kimura's disease: a case report". Oral ... FK-506 blood concentration was controlled within 5 to 15 μg/L. After 6 months, the dosage of tacrolimus was reduced to 0.5 mg ...
Canine discoid lupus erythematosus
Topical therapy includes corticosteroid and tacrolimus use. Oral vitamin E or omega-3 and omega-6 fatty acids are also used. ... Griffies J, Mendelsohn C, Rosenkrantz W, Muse R, Boord M, Griffin C (2004). "Topical 0.1% tacrolimus for the treatment of ... tacrolimus for the treatment of discoid lupus erythematosus and pemphigus erythematosus in dogs". Veterinary Dermatology. 13 (4 ...
Pityriasis alba
Tacrolimus has been reported as speeding resolution. In exceptionally severe cases PUVA therapy may be considered. The patches ... Rigopoulos D, Gregoriou S, Charissi C, Kontochristopoulos G, Kalogeromitros D, Georgala S (July 2006). "Tacrolimus ointment 0.1 ...
Eosinophilic folliculitis
Other therapies include PUVA, topical tacrolimus, and isotretinoin. Eosinophilic folliculitis associated with HIV infection ...
Thygeson's superficial punctate keratopathy
Tacrolimus (Protopic 0.03% ointment) is also an experimental treatment. Laser eye treatment. Amniotic membrane (Case Study) PRK ...
Efonidipine
Tacrolimus: Efonidipine inhibits metabolic enzymes involved in Tacrolimus metabolism and reduces its clearance. So, increase in ... blood concentration of Tacrolimus can occur. The common side effects are hot flushes, facial flushing and headache. In addition ...
Vitamin K reaction
Kang SY, Sohn KH, Lee JO, Kim SH, Cho SH, Chang YS (July 2015). "Intravenous tacrolimus and cyclosporine induced anaphylaxis: ...
C12orf40
Wong VW, You F, Januszyk M, Kuang AA (September 2013). "Tacrolimus fails to regulate collagen expression in dermal fibroblasts ... In the fibroblasts of hypertrophic scars, exposure to the immunosuppressant Tacrolimus causes C12orf40 up-regulation. In pigs, ...
Kidney transplantation
Tacrolimus, which is a similar drug, also causes nephrotoxicity. Blood levels of both must be monitored closely and if the ... The most common medication regimen today is a mixture of tacrolimus, mycophenolate, and prednisolone. Some recipients may ... These food products are known to interact with the transplant medications, specifically tacrolimus, cyclosporin and sirolimus; ... These include: azathioprine and mycophenolate, and ciclosporin and tacrolimus. The indication for kidney transplantation is end ...
Cirrhosis
Transplantation necessitates the use of immune suppressants (ciclosporin or tacrolimus). Manifestations of decompensation in ...
Jochen H.H. Ehrich
Randomized trial of tacrolimus versus cyclosporin microemulsion in renal transplantation. Pediatr Nephrol. 2002;17:141-9 Ehrich ...
Cheilitis
There have also been reports of using topical tacrolimus ointment. Chelitis glandularis is a rare inflammatory condition of the ...
Hives
Calcineurin inhibitors, such as cyclosporine and tacrolimus, inhibit cell responsiveness to mast cell products and inhibit T ... Immunosuppressants used for CU include cyclosporine, tacrolimus, sirolimus, and mycophenolate. ...
Mark G. Lebwohl
2004). "Tacrolimus ointment is effective for facial and intertriginous psoriasis". J Am Acad Dermatol. 51 (5): 723-30. doi: ...
Discoid lupus erythematosus
Other topical treatments, tacrolimus or pimecrolimus can also be used. If this does not help the patient, his or her physician ... Kouvelas, Dimitrios; Tzellos, Thrasivoulos George (2008-04-01). "Topical tacrolimus and pimecrolimus in the treatment of ...
Actinic prurigo
Prescribed treatments include: topical creams such as Tacrolimus and Betamethasone. systemic immunosuppressants such as ...
Sean P. Pinney
June 2006). "Long-term results of tacrolimus monotherapy in cardiac transplant recipients". J. Heart Lung Transplant. 25 (6): ...
Mefenamic acid
It can increase the kidney toxicity of ciclosporin and tacrolimus. Combination with antihypertensive drugs such as ACE ...